FR2822462B1 - Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene - Google Patents

Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene

Info

Publication number
FR2822462B1
FR2822462B1 FR0103979A FR0103979A FR2822462B1 FR 2822462 B1 FR2822462 B1 FR 2822462B1 FR 0103979 A FR0103979 A FR 0103979A FR 0103979 A FR0103979 A FR 0103979A FR 2822462 B1 FR2822462 B1 FR 2822462B1
Authority
FR
France
Prior art keywords
endogeneous
coagulation
exploring
activator compounds
activator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0103979A
Other languages
English (en)
Other versions
FR2822462A1 (fr
Inventor
Jean Paul Roisin
Stephane Steurs
Gerard Quentin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diagnostica Stago SAS
Original Assignee
Diagnostica Stago SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0103979A priority Critical patent/FR2822462B1/fr
Application filed by Diagnostica Stago SAS filed Critical Diagnostica Stago SAS
Priority to JP2002576184A priority patent/JP4563648B2/ja
Priority to CA002407779A priority patent/CA2407779A1/fr
Priority to CNB028007956A priority patent/CN100432046C/zh
Priority to PL02357449A priority patent/PL357449A1/xx
Priority to KR1020027015528A priority patent/KR20030005359A/ko
Priority to PCT/FR2002/001020 priority patent/WO2002076921A1/fr
Priority to BR0204494-3A priority patent/BR0204494A/pt
Priority to EP02722368A priority patent/EP1280758A1/fr
Priority to ARP020101046A priority patent/AR034221A1/es
Priority to MXPA02011565A priority patent/MXPA02011565A/es
Priority to HU0302136A priority patent/HUP0302136A3/hu
Priority to RU2002131457/04A priority patent/RU2002131457A/ru
Publication of FR2822462A1 publication Critical patent/FR2822462A1/fr
Priority to US10/302,649 priority patent/US7208266B2/en
Priority to HK03105405.5A priority patent/HK1054737A1/zh
Application granted granted Critical
Publication of FR2822462B1 publication Critical patent/FR2822462B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
FR0103979A 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene Expired - Fee Related FR2822462B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0103979A FR2822462B1 (fr) 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene
MXPA02011565A MXPA02011565A (es) 2001-03-23 2002-03-22 Compuestos activadores para coagulacion endogena - uso en la exploracion de coagulacion endogena.
CNB028007956A CN100432046C (zh) 2001-03-23 2002-03-22 内源性凝血激活化合物－在探查内源性凝血中的用途
PL02357449A PL357449A1 (en) 2001-03-23 2002-03-22 Gallic acid derivatives and use for exploring endogenetic coagulation
KR1020027015528A KR20030005359A (ko) 2001-03-23 2002-03-22 갈산 유도체 및 이의 내인성 응고의 검사를 위한 용도
PCT/FR2002/001020 WO2002076921A1 (fr) 2001-03-23 2002-03-22 Derives de l'acide gallique et utilisation pour l'exploration de la coagulation endogene
BR0204494-3A BR0204494A (pt) 2001-03-23 2002-03-22 Composto, composição, sistema de reativos, utilização de um composto, processo de preparação do mesmo, e, método de medida do tempo de tromboplastina parcialmente ativada
EP02722368A EP1280758A1 (fr) 2001-03-23 2002-03-22 Derives de l'acide gallique et utilisation pour l'exploration de la coagulation endogene
JP2002576184A JP4563648B2 (ja) 2001-03-23 2002-03-22 内因系凝固アクチベーター化合物−内因系凝固の診査における使用
CA002407779A CA2407779A1 (fr) 2001-03-23 2002-03-22 Derives de l'acide gallique et utilisation pour l'exploration de la coagulation endogene
HU0302136A HUP0302136A3 (en) 2001-03-23 2002-03-22 Gallic acid derivatives and use for exploring endogenetic coagulation
RU2002131457/04A RU2002131457A (ru) 2001-03-23 2002-03-22 Активаторы эндогенной коагуляции и их применение для исследования эндогенной коагуляции
ARP020101046A AR034221A1 (es) 2001-03-23 2002-03-22 Derivados de acido galico, un proceso para su preparacion, composicion farmaceutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulacion endogena, su utilizacion en la exploracion de la coagulacion endogena, y un metodo para medir el
US10/302,649 US7208266B2 (en) 2001-03-23 2002-11-22 Endogenous coagulation activator compounds —use in exploring endogenous coagulation
HK03105405.5A HK1054737A1 (zh) 2001-03-23 2003-07-25 五倍子酸衍生物及其探測內源性凝血的用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0103979A FR2822462B1 (fr) 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene

Publications (2)

Publication Number Publication Date
FR2822462A1 FR2822462A1 (fr) 2002-09-27
FR2822462B1 true FR2822462B1 (fr) 2005-07-15

Family

ID=8861494

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0103979A Expired - Fee Related FR2822462B1 (fr) 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene

Country Status (15)

Country Link
US (1) US7208266B2 (fr)
EP (1) EP1280758A1 (fr)
JP (1) JP4563648B2 (fr)
KR (1) KR20030005359A (fr)
CN (1) CN100432046C (fr)
AR (1) AR034221A1 (fr)
BR (1) BR0204494A (fr)
CA (1) CA2407779A1 (fr)
FR (1) FR2822462B1 (fr)
HK (1) HK1054737A1 (fr)
HU (1) HUP0302136A3 (fr)
MX (1) MXPA02011565A (fr)
PL (1) PL357449A1 (fr)
RU (1) RU2002131457A (fr)
WO (1) WO2002076921A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060406A2 (fr) * 2002-12-31 2004-07-22 Nektar Therapeutics Al, Corporation Reactifs polymeres comprenant une cetone ou un groupe fonctionnel apparente
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
JP6577778B2 (ja) * 2015-07-30 2019-09-18 シスメックス株式会社 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット
CN105424945B (zh) * 2015-11-20 2018-05-18 重庆贝羿生物科技有限公司 一种凝血激活检测试剂及其制备方法与用途
KR101651605B1 (ko) * 2015-12-10 2016-08-26 대봉엘에스 주식회사 신규 페놀산류 유도체 화합물, 및 이의 용도
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途
US20210405072A1 (en) * 2018-09-25 2021-12-30 Sekisui Medical Co., Ltd. Method for measuring blood coagulation time
CN110824154A (zh) * 2019-10-15 2020-02-21 常熟常江生物技术有限公司 用于血栓弹力图仪的激活剂
CN113679039B (zh) * 2021-05-12 2023-05-09 浙江大学 一种没食子酸聚乙二醇酯蛋白载体增效剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565823A (en) * 1976-11-11 1980-04-23 Pilkington Brothers Ltd Coating of glass fibres
JPS60199850A (ja) * 1984-03-26 1985-10-09 Eisai Co Ltd 新規な没食子酸誘導体
DE3544338A1 (de) * 1985-12-14 1987-06-19 Hoechst Ag Peptid-derivate mit inhibitorischer wirkung auf hydroxylierende enzyme, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
CA1313997C (fr) * 1986-04-11 1993-03-02 Hideo Anraku Accelerateur de l'activite de l'hydrolase
US4994192A (en) * 1990-01-16 1991-02-19 Eastman Kodak Company Amine polymers as coagulator accelerators in blood phase separation
US4979471A (en) * 1990-04-09 1990-12-25 Larry Hartshorn Animal confinement chute
JPH05506309A (ja) * 1990-04-17 1993-09-16 アナリティカル・コントロール・システムズ・インコーポレーテッド 凝固アッセイおよび試薬

Also Published As

Publication number Publication date
KR20030005359A (ko) 2003-01-17
CA2407779A1 (fr) 2002-10-03
CN1460098A (zh) 2003-12-03
RU2002131457A (ru) 2004-04-10
JP4563648B2 (ja) 2010-10-13
AR034221A1 (es) 2004-02-04
WO2002076921A1 (fr) 2002-10-03
CN100432046C (zh) 2008-11-12
US7208266B2 (en) 2007-04-24
US20030157582A1 (en) 2003-08-21
JP2004519507A (ja) 2004-07-02
HUP0302136A3 (en) 2005-12-28
HUP0302136A2 (hu) 2003-09-29
HK1054737A1 (zh) 2003-12-12
PL357449A1 (en) 2004-07-26
FR2822462A1 (fr) 2002-09-27
EP1280758A1 (fr) 2003-02-05
MXPA02011565A (es) 2004-09-06
BR0204494A (pt) 2003-04-08

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20061130

D3 Ip right revived
ST Notification of lapse

Effective date: 20141128