PE20000250A1 - Composiciones farmaceuticas para representar trombos en imagenes y tratarlos - Google Patents
Composiciones farmaceuticas para representar trombos en imagenes y tratarlosInfo
- Publication number
- PE20000250A1 PE20000250A1 PE1999000094A PE00009499A PE20000250A1 PE 20000250 A1 PE20000250 A1 PE 20000250A1 PE 1999000094 A PE1999000094 A PE 1999000094A PE 00009499 A PE00009499 A PE 00009499A PE 20000250 A1 PE20000250 A1 PE 20000250A1
- Authority
- PE
- Peru
- Prior art keywords
- apcitida
- bibapcitida
- thrombs
- treat
- images
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIERE A DIMEROS DE APCITIDA TAL COMO MONOCARBOXILATO DE BIBAPCITIDA Y BICARBOXILATO DE BIBAPCITIDA, QUE ESTAN PRESENTES EN SOLUCIONES ACUOSAS EN UN pH MAYOR DE 5. EL DIMERO DE BIBAPCITIDA SE FORMA A TRAVES DE UN ENLACE BISMALEIMIDA DE LAS CISTEINAS TERMINADAS EN CARBOXI DE LOS DOS MONOMEROS DE APCITIDA. LOS DIMEROS DE APCITIDA SE EMPLEAN COMO PRECURSORES PARA LA PRODUCCION DE APCITIDA RADIOMARCADA CON TECNECIO 99m (99m Tc), QUE SE UNEN AL RECEPTOR GPHb/IIIa DE LAS PLAQUETAS (UN COMPONENTE DE LOS TROMBOS) LOS QUE SE UTILIZAN PARA LA LOCALIZACION, LA CAPTACION Y EL DIAGNOSTICO DE TROMBOS IN VIVO POR LO QUE PUEDEN SER UTILES PARA EL TRATAMIENTO DE TROMBOSIS Y TROMBOEMBOLIA, EN PARTICULAR TROMBOSIS VENOSA PROFUNDA, EMBOLIA PULMONAR
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/020,086 US6028056A (en) | 1998-02-06 | 1998-02-06 | Pharmaceutical compositions for imaging and treating thrombi |
| GB9802681A GB9802681D0 (en) | 1998-02-06 | 1998-02-06 | Pharmaceutical compoations for imaging and treating thrombi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000250A1 true PE20000250A1 (es) | 2000-06-02 |
Family
ID=26313082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000094A PE20000250A1 (es) | 1998-02-06 | 1999-02-05 | Composiciones farmaceuticas para representar trombos en imagenes y tratarlos |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6028056A (es) |
| EP (1) | EP1053027B1 (es) |
| JP (1) | JP2003532617A (es) |
| KR (1) | KR100452390B1 (es) |
| CN (1) | CN1103606C (es) |
| AR (1) | AR018546A1 (es) |
| AT (1) | ATE279214T1 (es) |
| AU (1) | AU761778B2 (es) |
| BR (1) | BR9908352A (es) |
| CA (1) | CA2319544C (es) |
| DE (1) | DE69921096T2 (es) |
| DK (1) | DK1053027T3 (es) |
| EA (1) | EA005406B1 (es) |
| ES (1) | ES2229681T3 (es) |
| HK (1) | HK1032198A1 (es) |
| HU (1) | HUP0100887A3 (es) |
| IL (1) | IL137076A (es) |
| NO (1) | NO20003881L (es) |
| NZ (1) | NZ505085A (es) |
| PE (1) | PE20000250A1 (es) |
| PL (1) | PL342253A1 (es) |
| PT (1) | PT1053027E (es) |
| SI (1) | SI1053027T1 (es) |
| SK (1) | SK284463B6 (es) |
| TW (1) | TWI246425B (es) |
| WO (1) | WO1999039747A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2744802T (pt) | 2011-08-17 | 2017-03-15 | Piramal Imaging Sa | Compostos para ligação às glicoproteínas iib/iiia específicas de plaquetas e a sua utilização em imagiologia de trombos |
| JP2016508507A (ja) | 2013-02-12 | 2016-03-22 | バイエル・ファルマ・アクティエンゲゼルシャフト | 血小板特異的糖タンパク質ＩＩｂ／ＩＩＩａに結合するための金属キレート化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5645815A (en) * | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
| US5830856A (en) * | 1991-02-08 | 1998-11-03 | Diatide, Inc. | Radiolabeled compounds for thrombus imaging |
| US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
| DK0641222T3 (da) * | 1992-05-21 | 2000-12-11 | Diatide Inc | Peptider mærket med technetium-99m til trombeafbildning |
-
1998
- 1998-02-06 US US09/020,086 patent/US6028056A/en not_active Expired - Fee Related
-
1999
- 1999-02-04 AR ARP990100462A patent/AR018546A1/es unknown
- 1999-02-05 BR BR9908352-3A patent/BR9908352A/pt not_active IP Right Cessation
- 1999-02-05 SK SK1139-2000A patent/SK284463B6/sk unknown
- 1999-02-05 DE DE69921096T patent/DE69921096T2/de not_active Expired - Fee Related
- 1999-02-05 WO PCT/US1999/002583 patent/WO1999039747A1/en active IP Right Grant
- 1999-02-05 JP JP2000530244A patent/JP2003532617A/ja not_active Withdrawn
- 1999-02-05 EP EP99906771A patent/EP1053027B1/en not_active Expired - Lifetime
- 1999-02-05 CN CN99802698A patent/CN1103606C/zh not_active Expired - Fee Related
- 1999-02-05 AU AU26604/99A patent/AU761778B2/en not_active Ceased
- 1999-02-05 PL PL99342253A patent/PL342253A1/xx not_active IP Right Cessation
- 1999-02-05 AT AT99906771T patent/ATE279214T1/de not_active IP Right Cessation
- 1999-02-05 SI SI9930708T patent/SI1053027T1/xx unknown
- 1999-02-05 ES ES99906771T patent/ES2229681T3/es not_active Expired - Lifetime
- 1999-02-05 HU HU0100887A patent/HUP0100887A3/hu unknown
- 1999-02-05 PT PT99906771T patent/PT1053027E/pt unknown
- 1999-02-05 EA EA200000820A patent/EA005406B1/ru not_active IP Right Cessation
- 1999-02-05 CA CA002319544A patent/CA2319544C/en not_active Expired - Fee Related
- 1999-02-05 PE PE1999000094A patent/PE20000250A1/es not_active Application Discontinuation
- 1999-02-05 IL IL13707699A patent/IL137076A/en active IP Right Grant
- 1999-02-05 NZ NZ505085A patent/NZ505085A/xx unknown
- 1999-02-05 KR KR10-2000-7008551A patent/KR100452390B1/ko not_active IP Right Cessation
- 1999-02-05 DK DK99906771T patent/DK1053027T3/da active
- 1999-02-06 TW TW088101826A patent/TWI246425B/zh not_active IP Right Cessation
-
2000
- 2000-07-28 NO NO20003881A patent/NO20003881L/no not_active Application Discontinuation
-
2001
- 2001-02-23 HK HK01101351A patent/HK1032198A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |