IL136937A0 - τ-GLUTAMYL AND β-ASPARTYL CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - Google Patents

τ-GLUTAMYL AND β-ASPARTYL CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Info

Publication number
IL136937A0
IL136937A0 IL13693798A IL13693798A IL136937A0 IL 136937 A0 IL136937 A0 IL 136937A0 IL 13693798 A IL13693798 A IL 13693798A IL 13693798 A IL13693798 A IL 13693798A IL 136937 A0 IL136937 A0 IL 136937A0
Authority
IL
Israel
Prior art keywords
glutamyl
same
pharmaceutical compositions
aspartyl
compositions containing
Prior art date
Application number
IL13693798A
Other languages
English (en)
Original Assignee
Wei Edward
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26653944&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL136937(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from RU97120940/04A external-priority patent/RU2142958C1/ru
Application filed by Wei Edward filed Critical Wei Edward
Publication of IL136937A0 publication Critical patent/IL136937A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/305—Mercury compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13693798A 1997-12-25 1998-12-22 τ-GLUTAMYL AND β-ASPARTYL CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME IL136937A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU97120940/04A RU2142958C1 (ru) 1997-12-25 1997-12-25 Пептид, обладающий иммуномодулирующей активностью, и препарат на его основе
US09/031,842 US5916878A (en) 1995-11-28 1998-02-27 γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith
PCT/US1998/027291 WO1999033799A1 (en) 1997-12-25 1998-12-22 Gamma-glutamyl and beta-aspartyl containing immunomodulator compounds and methods therewith

Publications (1)

Publication Number Publication Date
IL136937A0 true IL136937A0 (en) 2001-06-14

Family

ID=26653944

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13693798A IL136937A0 (en) 1997-12-25 1998-12-22 τ-GLUTAMYL AND β-ASPARTYL CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Country Status (14)

Country Link
US (1) US5916878A (ja)
EP (1) EP1042286B1 (ja)
JP (1) JP4536918B2 (ja)
KR (2) KR100623104B1 (ja)
CN (1) CN1155571C (ja)
AU (1) AU754876B2 (ja)
BR (1) BR9814472A (ja)
CA (1) CA2316310C (ja)
CY (1) CY1111236T1 (ja)
IL (1) IL136937A0 (ja)
MX (1) MXPA00006369A (ja)
NO (1) NO317256B1 (ja)
NZ (1) NZ505489A (ja)
WO (1) WO1999033799A1 (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2089179C1 (ru) * 1995-12-14 1997-09-10 Закрытое акционерное общество "ВАМ" Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования
US6251857B1 (en) 1995-12-14 2001-06-26 Novelos Therapeutics, Inc. Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof
RU2144374C1 (ru) 1998-11-23 2000-01-20 Закрытое акционерное общество "ВАМ" Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток
US20070142267A1 (en) * 1998-11-23 2007-06-21 Novelos Therapeutics, Inc. Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
WO2000063238A1 (en) * 1999-04-15 2000-10-26 Thymon, L.L.C. Nonextractive method of assaying thymopoietin
JP2004503604A (ja) * 2000-07-24 2004-02-05 ザ・ユニバーシティ・オブ・クイーンズランド 化合物およびホスホリパーゼ阻害剤
AU7223401A (en) * 2000-07-24 2002-02-05 Univ Queensland Compounds and inhibitors of phospholipases
RU2229892C2 (ru) 2001-06-08 2004-06-10 Государственное учреждение "Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии" Способ лечения туберкулеза легких
US7173013B2 (en) * 2001-06-08 2007-02-06 Sciclone Pharmaceuticals, Inc. Treatment of tuberculosis using immunomodulator compounds
GB0500020D0 (en) 2005-01-04 2005-02-09 Novartis Ag Organic compounds
CN1964731A (zh) * 2004-05-14 2007-05-16 希克龙制药公司 用免疫调节剂化合物治疗或预防呼吸道病素性感染
US8193152B2 (en) * 2004-10-27 2012-06-05 The Board Of Regents Of The University Of Texas System Treatment or prevention of hemorrhagic viral infections with immunomodulator compounds
WO2006116053A1 (en) * 2005-04-22 2006-11-02 Sciclone Pharmaceuticals, Inc. Immunomodulator compounds as vaccine enhancers
BRPI0711567A2 (pt) * 2006-04-20 2011-11-08 Sciclone Pharmaceuticals Inc uso de um composto imunomodulador para tratamento de melanoma
RU2301074C1 (ru) * 2006-05-30 2007-06-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Пептид, обладающий иммуногеропротекторным действием, фармацевтическая композиция на его основе и способ ее применения
CA2569204A1 (en) 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
UA96980C2 (ru) * 2007-02-13 2011-12-26 Сайклон Фармасютикалс, Инк. Способ уменьшения степени ухудшения состояния, поражения или повреждения слизистой оболочки
CA2579119C (en) * 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
RU2007118237A (ru) * 2007-05-17 2008-11-27 ООО "Научно-производственна фирма Верта" (RU) Способ лечения аллергических заболеваний
JP2010536854A (ja) * 2007-08-23 2010-12-02 サイクローン・ファーマシューティカルズ・インコーポレイテッド 肺ガンの治療
WO2010073870A1 (ja) * 2008-12-24 2010-07-01 学校法人 慶應義塾 肝臓疾患マーカー、その測定方法、装置及び医薬品の検定方法
US20110064828A1 (en) * 2009-09-11 2011-03-17 Novelos Therapeutics, Incorporated Treatment of metastatic tumors and other conditions
WO2012040656A2 (en) * 2010-09-24 2012-03-29 Sciclone Pharmaceuticals, Inc. Biomarkers to track response to scv-07
CN102417474B (zh) * 2011-09-26 2014-07-02 深圳翰宇药业股份有限公司 D-异谷氨酰基-d-色氨酸制备的新方法
WO2013155595A1 (en) * 2012-04-18 2013-10-24 Apotex Technologies Inc. Process for the preparation of a monosodium salt of h-d-glu-(l-trp-oh)-oh and a crystalline form thereof
WO2013155592A1 (en) * 2012-04-18 2013-10-24 Apotex Technologies Inc. Crystal forms of golotimod and process for its manufacturing
RU2635968C1 (ru) * 2016-11-17 2017-11-17 Аллан Герович Бениашвили Способ лечения и профилактики состояний аллергического спектра

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125626A (en) * 1977-01-17 1978-11-14 Mt. Sinai School Of Medicine Of The City University Of New York Synthesis and use of L-γ-glutamyl-DOPA
US4568489A (en) * 1984-06-29 1986-02-04 E. R. Squibb & Sons, Inc. N-Acyl-γ-glutamyl imino and amino acids and esters
US4758551A (en) * 1986-07-08 1988-07-19 Cornell Research Foundation, Inc. Methods for combatting renal toxicity due to metals or nephrotoxic drugs and for selectively modulating in vivo formation of leukotriene types
US5206220A (en) * 1990-04-23 1993-04-27 Research Corporation Technologies, Inc. Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition
CA2107460A1 (en) * 1991-04-01 1992-10-02 Vladimir K. Khavinson Pharmaceutical dipeptide compositions and methods of use thereof
GB9113219D0 (en) * 1991-06-19 1991-08-07 Fujisawa Pharmaceutical Co Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
AU2905092A (en) * 1991-10-28 1993-06-07 Cytoven Pharmaceutical dipeptide compositions and methods of use thereof
WO1994020063A2 (en) * 1993-03-04 1994-09-15 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
RU2107692C1 (ru) * 1995-06-07 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
WO1997019691A1 (en) * 1995-11-28 1997-06-05 Wei, Edward, T. Gamma-l-glutamyl containing immunomodulator compounds and methods therewith
US5744452A (en) * 1995-11-28 1998-04-28 Edward T. Wei γ-L-glutamyl containing immunomodulator compounds and methods therewith

Also Published As

Publication number Publication date
KR20060057027A (ko) 2006-05-25
NZ505489A (en) 2003-02-28
US5916878A (en) 1999-06-29
EP1042286A1 (en) 2000-10-11
CN1155571C (zh) 2004-06-30
KR100602529B1 (ko) 2006-07-19
EP1042286B1 (en) 2010-08-25
CA2316310C (en) 2008-02-19
CY1111236T1 (el) 2015-06-11
CN1284943A (zh) 2001-02-21
AU2090999A (en) 1999-07-19
JP2001527065A (ja) 2001-12-25
JP4536918B2 (ja) 2010-09-01
KR100623104B1 (ko) 2006-09-15
AU754876B2 (en) 2002-11-28
KR20010033617A (ko) 2001-04-25
BR9814472A (pt) 2001-10-23
NO20003312L (no) 2000-08-21
NO317256B1 (no) 2004-09-27
MXPA00006369A (es) 2002-08-06
NO20003312D0 (no) 2000-06-23
CA2316310A1 (en) 1999-07-08
WO1999033799A1 (en) 1999-07-08

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees