IL136549A - Orally administrable solid ribavirin dosage forms and process for making them - Google Patents

Orally administrable solid ribavirin dosage forms and process for making them

Info

Publication number
IL136549A
IL136549A IL13654998A IL13654998A IL136549A IL 136549 A IL136549 A IL 136549A IL 13654998 A IL13654998 A IL 13654998A IL 13654998 A IL13654998 A IL 13654998A IL 136549 A IL136549 A IL 136549A
Authority
IL
Israel
Prior art keywords
making
dosage forms
orally administrable
administrable solid
ribavirin dosage
Prior art date
Application number
IL13654998A
Other languages
English (en)
Other versions
IL136549A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL136549(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/997,172 external-priority patent/US5914128A/en
Priority claimed from US08/997,169 external-priority patent/US5916594A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL136549A0 publication Critical patent/IL136549A0/xx
Publication of IL136549A publication Critical patent/IL136549A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13654998A 1997-12-22 1998-12-21 Orally administrable solid ribavirin dosage forms and process for making them IL136549A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/997,172 US5914128A (en) 1997-12-22 1997-12-22 Orally administrable solid dosage form
US08/997,169 US5916594A (en) 1997-12-22 1997-12-22 Process of making solid ribavirin dosage forms
PCT/US1998/026222 WO1999032128A1 (fr) 1997-12-22 1998-12-21 Forme posologique solide et orale, comprenant de la ribavirine, et son procede de fabrication

Publications (2)

Publication Number Publication Date
IL136549A0 IL136549A0 (en) 2001-06-14
IL136549A true IL136549A (en) 2005-05-17

Family

ID=27130673

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13654998A IL136549A (en) 1997-12-22 1998-12-21 Orally administrable solid ribavirin dosage forms and process for making them

Country Status (27)

Country Link
US (3) US6337090B1 (fr)
EP (2) EP0991415B1 (fr)
JP (2) JP2001526234A (fr)
KR (1) KR100575389B1 (fr)
CN (1) CN1155388C (fr)
AR (1) AR008977A1 (fr)
AT (1) ATE234103T1 (fr)
AU (1) AU762826B2 (fr)
BR (1) BR9814367A (fr)
CA (4) CA2287056C (fr)
CO (1) CO4970774A1 (fr)
DE (1) DE69812094T2 (fr)
DK (1) DK0991415T3 (fr)
ES (1) ES2191987T3 (fr)
HK (1) HK1034674A1 (fr)
HU (1) HUP0100433A3 (fr)
IL (1) IL136549A (fr)
MY (1) MY119656A (fr)
NO (1) NO20003234L (fr)
NZ (1) NZ504994A (fr)
PE (1) PE20000066A1 (fr)
PL (1) PL190267B1 (fr)
PT (1) PT991415E (fr)
SK (1) SK284520B6 (fr)
TW (1) TW575436B (fr)
WO (1) WO1999032128A1 (fr)
ZA (1) ZA9811726B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL190267B1 (pl) * 1997-12-22 2005-11-30 Schering Corp Stała postać dawkowania do podawania doustnego zawierająca rybawirynę i sposób jej wytwarzania
US6793934B1 (en) * 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
EP1263341B1 (fr) * 2000-03-06 2008-06-11 Salient Surgical Technologies, Inc. Systeme et regulateur de distribution de fluide pour dispositifs d'electrochirurgie
US6720000B2 (en) * 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
KR20030020137A (ko) * 2001-09-03 2003-03-08 진양제약주식회사 리바비린 건조시럽제
MXPA04004181A (es) * 2001-11-02 2005-01-25 Sandoz Ag Procedimiento para preparar composiciones de ribavirina de alta carga, de rapida disolucion.
DE10227148A1 (de) * 2002-06-18 2004-01-08 Biopartners Gmbh Verwendung von Ribavirin zur Herstellung einer pharmazeutischen Zusammensetzung gegen Bunyaviridae
US7538094B2 (en) * 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
US20040142903A1 (en) * 2003-01-16 2004-07-22 Par Pharmaceutical Inc. Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
WO2004084796A2 (fr) * 2003-03-28 2004-10-07 Pharmasset Ltd. Composes permettant de traiter les infections par flavivirus
US20080076830A1 (en) * 2004-09-09 2008-03-27 Bayer Healthcare Ag Pharmaceutical Composition in the Form of a Water Soluble Solid Dosage Form
US7723310B2 (en) * 2004-10-18 2010-05-25 Three Rivers Pharmaceuticals, Llc Large dose ribavirin formulations
US8062670B2 (en) * 2005-08-05 2011-11-22 3M Innovative Properties Company Compositions exhibiting improved flowability
JP2010510171A (ja) * 2006-08-21 2010-04-02 ユナイテッド セラピューティクス コーポレーション ウイルス感染症の治療のための併用療法
US9072664B2 (en) * 2008-05-22 2015-07-07 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
EP2309978B1 (fr) * 2008-06-26 2018-12-26 3M Innovative Properties Company Compositions pharmaceutiques de poudre sèche pour une administration pulmonaire et leurs procédés de fabrication
EP2309984B1 (fr) * 2008-07-02 2018-04-11 3M Innovative Properties Company Procédé de fabrication d'une composition pharmaceutique en poudre sèche
EP2295037A1 (fr) 2009-09-11 2011-03-16 Ratiopharm GmbH Formule pharmaceutique contenant de la ribavirine
US10363453B2 (en) 2011-02-07 2019-07-30 New Balance Athletics, Inc. Systems and methods for monitoring athletic and physiological performance
CA2752008A1 (fr) 2011-09-13 2013-03-13 Universite De Montreal Therapie combinee utilisant de la ribavirine a titre d'inhibiteur de l'elf4e
CN106389363A (zh) * 2016-10-18 2017-02-15 广东肇庆星湖生物科技股份有限公司 一种利巴韦林口服固体制剂及其制备方法

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DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
US4211771A (en) * 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
DE2735600A1 (de) * 1977-08-06 1979-02-15 Dynamit Nobel Ag Verfahren zur herstellung von phthalid
JPS57146593A (en) * 1981-03-09 1982-09-10 Ajinomoto Co Inc Preparation of ribofuranosyltriazole derivative
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
JPS63216820A (ja) * 1987-03-05 1988-09-09 Chugai Pharmaceut Co Ltd 抗ウイルス剤
GB8800276D0 (en) * 1988-01-07 1988-02-10 Univ Liverpool Medical treatment
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
US5122517A (en) * 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
JP2908844B2 (ja) * 1990-06-29 1999-06-21 ヤマサ醤油株式会社 抗ウイルス剤
ATE178335T1 (de) * 1992-01-06 1999-04-15 Wellcome Found Therapeutische nukleoside der 2',3'-dideoxy-3'- fluor -purin reihe
US5869097A (en) * 1992-11-02 1999-02-09 Alza Corporation Method of therapy comprising an osmotic caplet
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JPH06298665A (ja) * 1993-04-14 1994-10-25 Toray Ind Inc 抗ウイルス剤
US5506248A (en) * 1993-08-02 1996-04-09 Bristol-Myers Squibb Company Pharmaceutical compositions having good dissolution properties
US5492692A (en) * 1993-08-17 1996-02-20 University Of Kentucky Research Foundation Coated products with potent anti-HIV and antimicrobial properties
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
CA2135669A1 (fr) * 1994-11-10 1996-05-11 Nils O. Johannesson Ribavirine servant d'agent protecteur hepatique
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
IL139728A (en) * 1995-01-09 2003-06-24 Penwest Pharmaceuticals Compan Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient
DK0812195T3 (da) * 1995-02-28 2003-03-03 Aventis Pharma Inc Farmaceutisk sammensætning til piperidinoalkanolforbindelser
US6387365B1 (en) * 1995-05-19 2002-05-14 Schering Corporation Combination therapy for chronic hepatitis C infection
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5723589A (en) * 1995-12-21 1998-03-03 Icn Pharmaceuticals Carbohydrate conjugated bio-active compounds
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US6172046B1 (en) * 1997-09-21 2001-01-09 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
US5916594A (en) * 1997-12-22 1999-06-29 Schering Corporation Process of making solid ribavirin dosage forms
PL190267B1 (pl) * 1997-12-22 2005-11-30 Schering Corp Stała postać dawkowania do podawania doustnego zawierająca rybawirynę i sposób jej wytwarzania

Also Published As

Publication number Publication date
KR100575389B1 (ko) 2006-05-03
EP1321147A1 (fr) 2003-06-25
CA2287056C (fr) 2000-08-15
HUP0100433A3 (en) 2003-01-28
CA2300452A1 (fr) 1999-07-01
HUP0100433A2 (hu) 2001-12-28
IL136549A0 (en) 2001-06-14
AR008977A1 (es) 2000-03-08
CA2300452C (fr) 2000-11-28
WO1999032128A1 (fr) 1999-07-01
CA2365412C (fr) 2002-09-17
CO4970774A1 (es) 2000-11-07
CN1155388C (zh) 2004-06-30
KR20010033441A (ko) 2001-04-25
PE20000066A1 (es) 2000-02-09
US6051252A (en) 2000-04-18
US6335032B1 (en) 2002-01-01
NO20003234L (no) 2000-08-21
US6337090B1 (en) 2002-01-08
CN1283117A (zh) 2001-02-07
AU762826B2 (en) 2003-07-03
DE69812094D1 (de) 2003-04-17
ATE234103T1 (de) 2003-03-15
MY119656A (en) 2005-06-30
ZA9811726B (en) 1999-06-21
PT991415E (pt) 2003-06-30
PL341230A1 (en) 2001-03-26
JP2001526234A (ja) 2001-12-18
NO20003234D0 (no) 2000-06-21
HK1034674A1 (en) 2001-11-02
ES2191987T3 (es) 2003-09-16
TW575436B (en) 2004-02-11
SK284520B6 (sk) 2005-05-05
DE69812094T2 (de) 2003-12-24
EP0991415A1 (fr) 2000-04-12
JP2006083189A (ja) 2006-03-30
CA2365412A1 (fr) 1999-07-01
CA2323849C (fr) 2002-06-11
PL190267B1 (pl) 2005-11-30
DK0991415T3 (da) 2003-06-16
EP0991415B1 (fr) 2003-03-12
CA2287056A1 (fr) 1999-07-01
NZ504994A (en) 2002-10-25
CA2323849A1 (fr) 1999-07-01
BR9814367A (pt) 2000-10-17
AU2199199A (en) 1999-07-12
SK8942000A3 (en) 2001-04-09

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees