DK0991415T3 - Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse - Google Patents

Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse

Info

Publication number
DK0991415T3
DK0991415T3 DK98965983T DK98965983T DK0991415T3 DK 0991415 T3 DK0991415 T3 DK 0991415T3 DK 98965983 T DK98965983 T DK 98965983T DK 98965983 T DK98965983 T DK 98965983T DK 0991415 T3 DK0991415 T3 DK 0991415T3
Authority
DK
Denmark
Prior art keywords
ribavirin
preparation
dosage forms
oral dosage
solid oral
Prior art date
Application number
DK98965983T
Other languages
Danish (da)
English (en)
Inventor
Stephen M Liebowitz
Elliot I Stupak
Imtiaz A Chaudry
Winston A Vadino
Frank E Bowen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0991415(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/997,172 external-priority patent/US5914128A/en
Priority claimed from US08/997,169 external-priority patent/US5916594A/en
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0991415T3 publication Critical patent/DK0991415T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK98965983T 1997-12-22 1998-12-21 Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse DK0991415T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/997,172 US5914128A (en) 1997-12-22 1997-12-22 Orally administrable solid dosage form
US08/997,169 US5916594A (en) 1997-12-22 1997-12-22 Process of making solid ribavirin dosage forms
PCT/US1998/026222 WO1999032128A1 (fr) 1997-12-22 1998-12-21 Forme posologique solide et orale, comprenant de la ribavirine, et son procede de fabrication

Publications (1)

Publication Number Publication Date
DK0991415T3 true DK0991415T3 (da) 2003-06-16

Family

ID=27130673

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98965983T DK0991415T3 (da) 1997-12-22 1998-12-21 Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse

Country Status (27)

Country Link
US (3) US6337090B1 (fr)
EP (2) EP0991415B1 (fr)
JP (2) JP2001526234A (fr)
KR (1) KR100575389B1 (fr)
CN (1) CN1155388C (fr)
AR (1) AR008977A1 (fr)
AT (1) ATE234103T1 (fr)
AU (1) AU762826B2 (fr)
BR (1) BR9814367A (fr)
CA (4) CA2323849C (fr)
CO (1) CO4970774A1 (fr)
DE (1) DE69812094T2 (fr)
DK (1) DK0991415T3 (fr)
ES (1) ES2191987T3 (fr)
HK (1) HK1034674A1 (fr)
HU (1) HUP0100433A3 (fr)
IL (1) IL136549A (fr)
MY (1) MY119656A (fr)
NO (1) NO20003234L (fr)
NZ (1) NZ504994A (fr)
PE (1) PE20000066A1 (fr)
PL (1) PL190267B1 (fr)
PT (1) PT991415E (fr)
SK (1) SK284520B6 (fr)
TW (1) TW575436B (fr)
WO (1) WO1999032128A1 (fr)
ZA (1) ZA9811726B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2323849C (fr) * 1997-12-22 2002-06-11 Schering Corporation Forme posologique solide et orale, comprenant de la ribavirine, et son procede de fabrication
US6793934B1 (en) * 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
AU2001239987A1 (en) * 2000-03-06 2001-09-17 Tissuelink Medical, Inc. Fluid delivery system and controller for electrosurgical devices
US6720000B2 (en) * 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
KR20030020137A (ko) * 2001-09-03 2003-03-08 진양제약주식회사 리바비린 건조시럽제
HUP0402364A2 (hu) * 2001-11-02 2005-02-28 Sandoz Ag Gyorsan oldódó, nagy koncentrációjú ribavirinkészítmények
DE10227148A1 (de) * 2002-06-18 2004-01-08 Biopartners Gmbh Verwendung von Ribavirin zur Herstellung einer pharmazeutischen Zusammensetzung gegen Bunyaviridae
US7538094B2 (en) * 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
US20040142903A1 (en) * 2003-01-16 2004-07-22 Par Pharmaceutical Inc. Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
RU2005133093A (ru) * 2003-03-28 2006-07-27 Фармассет, Инк. (Us) Соединения для лечения флавивирусных инфекций
MX2007002784A (es) * 2004-09-09 2009-02-12 Bayer Animal Health Gmbh Composición farmacéutica en forma de dosificación sólida soluble en agua.
US7723310B2 (en) * 2004-10-18 2010-05-25 Three Rivers Pharmaceuticals, Llc Large dose ribavirin formulations
WO2007019229A1 (fr) * 2005-08-05 2007-02-15 3M Innovative Properties Company Compositions présentant une aptitude à l’écoulement améliorée
WO2008063727A2 (fr) * 2006-08-21 2008-05-29 United Therapeutics Corporation Polytherapie destinée a traiter des infections virales
WO2009142852A2 (fr) * 2008-05-22 2009-11-26 3M Innovative Properties Company Procédé de fabrication de compositions médicamenteuses pulvérulentes coulables
US9956170B2 (en) * 2008-06-26 2018-05-01 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
WO2010002613A2 (fr) * 2008-07-02 2010-01-07 3M Innovative Properties Company Procédé de fabrication d’une composition pharmaceutique en poudre sèche
EP2295037A1 (fr) 2009-09-11 2011-03-16 Ratiopharm GmbH Formule pharmaceutique contenant de la ribavirine
US10363453B2 (en) 2011-02-07 2019-07-30 New Balance Athletics, Inc. Systems and methods for monitoring athletic and physiological performance
CA2752008A1 (fr) 2011-09-13 2013-03-13 Universite De Montreal Therapie combinee utilisant de la ribavirine a titre d'inhibiteur de l'elf4e
CN106389363A (zh) * 2016-10-18 2017-02-15 广东肇庆星湖生物科技股份有限公司 一种利巴韦林口服固体制剂及其制备方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
US4211771A (en) * 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
DE2735600A1 (de) * 1977-08-06 1979-02-15 Dynamit Nobel Ag Verfahren zur herstellung von phthalid
JPS57146593A (en) * 1981-03-09 1982-09-10 Ajinomoto Co Inc Preparation of ribofuranosyltriazole derivative
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
JPS63216820A (ja) * 1987-03-05 1988-09-09 Chugai Pharmaceut Co Ltd 抗ウイルス剤
GB8800276D0 (en) * 1988-01-07 1988-02-10 Univ Liverpool Medical treatment
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5122517A (en) * 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
JP2908844B2 (ja) * 1990-06-29 1999-06-21 ヤマサ醤油株式会社 抗ウイルス剤
DK0625158T3 (da) * 1992-01-06 1999-10-11 Wellcome Found Terapeutiske nucleosider af 2',3'-dideoxy-3'-fluorpurinrækken
US5869097A (en) * 1992-11-02 1999-02-09 Alza Corporation Method of therapy comprising an osmotic caplet
US5358721A (en) * 1992-12-04 1994-10-25 Alza Corporation Antiviral therapy
JPH06298665A (ja) * 1993-04-14 1994-10-25 Toray Ind Inc 抗ウイルス剤
US5506248A (en) * 1993-08-02 1996-04-09 Bristol-Myers Squibb Company Pharmaceutical compositions having good dissolution properties
US5492692A (en) * 1993-08-17 1996-02-20 University Of Kentucky Research Foundation Coated products with potent anti-HIV and antimicrobial properties
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
CA2135669A1 (fr) 1994-11-10 1996-05-11 Nils O. Johannesson Ribavirine servant d'agent protecteur hepatique
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
EP0812195B1 (fr) * 1995-02-28 2002-10-30 Aventis Pharmaceuticals Inc. Composition pharmaceutique pour composes de piperidinoalcanol
US6387365B1 (en) * 1995-05-19 2002-05-14 Schering Corporation Combination therapy for chronic hepatitis C infection
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5723589A (en) * 1995-12-21 1998-03-03 Icn Pharmaceuticals Carbohydrate conjugated bio-active compounds
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US6172046B1 (en) * 1997-09-21 2001-01-09 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
US5916594A (en) * 1997-12-22 1999-06-29 Schering Corporation Process of making solid ribavirin dosage forms
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
CA2323849C (fr) * 1997-12-22 2002-06-11 Schering Corporation Forme posologique solide et orale, comprenant de la ribavirine, et son procede de fabrication

Also Published As

Publication number Publication date
JP2006083189A (ja) 2006-03-30
TW575436B (en) 2004-02-11
WO1999032128A1 (fr) 1999-07-01
CA2365412C (fr) 2002-09-17
CO4970774A1 (es) 2000-11-07
PL190267B1 (pl) 2005-11-30
AU2199199A (en) 1999-07-12
DE69812094T2 (de) 2003-12-24
KR100575389B1 (ko) 2006-05-03
IL136549A0 (en) 2001-06-14
NO20003234L (no) 2000-08-21
EP0991415A1 (fr) 2000-04-12
SK8942000A3 (en) 2001-04-09
CN1155388C (zh) 2004-06-30
HUP0100433A3 (en) 2003-01-28
EP1321147A1 (fr) 2003-06-25
CA2300452C (fr) 2000-11-28
NO20003234D0 (no) 2000-06-21
HK1034674A1 (en) 2001-11-02
CA2323849A1 (fr) 1999-07-01
KR20010033441A (ko) 2001-04-25
CN1283117A (zh) 2001-02-07
BR9814367A (pt) 2000-10-17
NZ504994A (en) 2002-10-25
AR008977A1 (es) 2000-03-08
MY119656A (en) 2005-06-30
CA2323849C (fr) 2002-06-11
ES2191987T3 (es) 2003-09-16
CA2300452A1 (fr) 1999-07-01
US6335032B1 (en) 2002-01-01
SK284520B6 (sk) 2005-05-05
IL136549A (en) 2005-05-17
ATE234103T1 (de) 2003-03-15
ZA9811726B (en) 1999-06-21
HUP0100433A2 (hu) 2001-12-28
US6051252A (en) 2000-04-18
PT991415E (pt) 2003-06-30
EP0991415B1 (fr) 2003-03-12
CA2365412A1 (fr) 1999-07-01
DE69812094D1 (de) 2003-04-17
CA2287056C (fr) 2000-08-15
JP2001526234A (ja) 2001-12-18
PE20000066A1 (es) 2000-02-09
US6337090B1 (en) 2002-01-08
CA2287056A1 (fr) 1999-07-01
AU762826B2 (en) 2003-07-03
PL341230A1 (en) 2001-03-26

Similar Documents

Publication Publication Date Title
DK0991415T3 (da) Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse
NO20011084L (no) Presisjonstidsstyrende generatorsystem og fremgangsmåte.
DK1066049T3 (da) Farmaceutiske præparater, der er beregnet til langvarig frigivelse af peptider og fremgangsmåde til fremstilling af disse
DK1112251T3 (da) Azetidinderivater, deres fremstilling og medikamenter indeholdende disse derivater
DK1156049T3 (da) Substituerede heterocykliske forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK0817780T3 (da) Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser
DK1767206T3 (da) Faste orale doseringsformer indeholdende valsartan og hydrochlorhiazid
NO308738B1 (no) Bicyklisk kondenserte pyridiner, legemidler inneholdende disse og anvendelse av forbindelsene for fremstilling av legemidler
IS2321B (is) Aðferðir og blöndur til að fyrirbyggja þol gegn berkjuvíkkandi lyfjum
NO20031152D0 (no) Befruktningshindrende fremgangsmåte og administrasjonsform for det samme
NO984406D0 (no) Gulvdel, fremgangsmÕte til fremstilling av en slik gulvdel og innretning til dette bruk
NO20032332L (no) Benzodiazepinderivatforbindelser, fremgangsmåte til fremstilling og anvendelse derav
DK1140824T3 (da) Fremgangsmåde til fremstilling af 3-alkanoyl- og 3-alkylindoler
DK0981377T3 (da) Komplekser af LHRH-antagonisten Cetrorelix med polyaminosyrer og fremgangsmåder til deres fremstilling
NO20000853L (no) Polysiloksanbaserte blokk-kopolymerer og fremgangsmÕte for fremstilling av disse
MXPA03003682A (es) Metodo para determinar la coagulabilidad y el potencial hemostatico globales.
NO20015659L (no) Purinderivater, fremstillingsmetode og farmasöytiske preparater inneholdende disse
NO20026212D0 (no) Forbindelse for medikamentavleveringssystem og fremgangsmåte for fremstilling av forbindelsen
DK1049721T3 (da) Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse
DK0994706T3 (da) Præparater til oral indgivelse af taxaner og anvendelse deraf
ID23187A (id) Bentuk bentuk dosis sertralina lepas tunda
DK1015433T3 (da) Substituerede 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-oler, fremgangsmåder til fremstilling af disse og deres anvendelse som lægemidler
DK1178799T3 (da) Gastrobeskyttede mikrogranula, fremgangsmåde til opnåelse af samme og farmaceutiske præparater
DK0864564T3 (da) Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater
NO20000023D0 (no) Gjoedselpreparater med kontrollert frigivelse og fremgangsmåte for fremstilling av disse