IL134917A - Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof - Google Patents

Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Info

Publication number
IL134917A
IL134917A IL13491795A IL13491795A IL134917A IL 134917 A IL134917 A IL 134917A IL 13491795 A IL13491795 A IL 13491795A IL 13491795 A IL13491795 A IL 13491795A IL 134917 A IL134917 A IL 134917A
Authority
IL
Israel
Prior art keywords
hydroxydiphenylmethyl
water
piperidinyl
hydroxybutyl
minutes
Prior art date
Application number
IL13491795A
Other languages
English (en)
Original Assignee
Marion Merrell Dow Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL134917(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc
Publication of IL134917A publication Critical patent/IL134917A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
IL13491795A 1994-05-18 1995-05-16 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof IL134917A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11
IL11374795A IL113747A (en) 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof

Publications (1)

Publication Number Publication Date
IL134917A true IL134917A (en) 2001-07-24

Family

ID=26937420

Family Applications (3)

Application Number Title Priority Date Filing Date
IL11374795A IL113747A (en) 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof
IL13491795A IL134917A (en) 1994-05-18 1995-05-16 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en) 1994-05-18 2000-03-07 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL11374795A IL113747A (en) 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13491700A IL134917A0 (en) 1994-05-18 2000-03-07 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Country Status (18)

Country Link
US (12) US20010012896A1 (fi)
EP (3) EP0766668B1 (fi)
JP (7) JPH10500134A (fi)
CN (3) CN1907967B (fi)
AT (1) ATE220667T1 (fi)
AU (1) AU693892B2 (fi)
CA (3) CA2585705C (fi)
DE (1) DE69527429T2 (fi)
DK (1) DK0766668T3 (fi)
ES (1) ES2176329T3 (fi)
FI (1) FI964565A0 (fi)
HK (2) HK1098467A1 (fi)
HU (1) HU227676B1 (fi)
IL (3) IL113747A (fi)
MX (1) MX9605613A (fi)
NO (1) NO315319B1 (fi)
PT (1) PT766668E (fi)
WO (1) WO1995031437A1 (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135571B2 (en) 1994-05-18 2006-11-14 Aventis Pharmaceuticals, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

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GB9400555D0 (en) * 1994-01-13 1994-03-09 Short Brothers Plc Boundery layer control in aerodynamic low drag structures
HUP9802086A3 (en) 1995-02-28 2001-02-28 Aventis Pharmaceuticals Inc Br Pharmaceutical composition for piperidinoalkanol compounds
CZ295461B6 (cs) * 1997-08-26 2005-08-17 Aventis Pharmaceuticals Inc. Farmaceutický prostředek ve formě dvouvrstvé tablety
IN191492B (fi) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) * 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
CH695216A5 (de) 2001-02-23 2006-01-31 Cilag Ag Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
EP1392303A4 (en) * 2001-04-09 2005-01-26 Teva Pharma FEXOFENADINE HYDROCHLORIDE POLYMORPHS
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
CN100390145C (zh) * 2001-06-18 2008-05-28 雷迪实验室有限公司 4-[4-[4-(羟基二苯基甲基)-1-哌啶基]-1-羟基丁基]-α,α-二甲基苯乙酸和其盐酸盐的结晶形式
US7700779B2 (en) * 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
ATE389405T1 (de) * 2001-07-31 2008-04-15 Texcontor Ets Fexofenadine hydrochlorid polymorph
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
JP2005532356A (ja) * 2002-06-10 2005-10-27 テバ ファーマシューティカル インダストリーズ リミティド 塩酸フェキソフェナジンの多型体ｘｖｉ
JP3910907B2 (ja) * 2002-10-29 2007-04-25 新光電気工業株式会社 キャパシタ素子及びこの製造方法、半導体装置用基板、並びに半導体装置
CA2530193A1 (en) * 2003-07-03 2005-01-20 Teva Pharmaceutical Industries Ltd. Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
WO2005102999A2 (en) * 2004-04-26 2005-11-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of fexofenadine hydrochloride and processes for their preparation
ITMI20041143A1 (it) * 2004-06-08 2004-09-08 Dipharma Spa Polimorfi di fexofenadina e procedimento per la loro preparazione
EP1616861A3 (en) * 2004-06-15 2006-02-08 Dipharma S.p.A. A process for the preparation of keto compounds
ITMI20041568A1 (it) * 2004-07-30 2004-10-30 Dipharma Spa "polimorfi di fexofenadina base"
EP1685106A2 (en) * 2004-09-28 2006-08-02 Teva Pharmaceutical Industries, Inc. Fexofendadine crystal form and processes for its preparation thereof
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
KR20090037930A (ko) * 2006-07-11 2009-04-16 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. 조절 방출 제형
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
US20090306135A1 (en) 2008-03-24 2009-12-10 Mukesh Kumar Sharma Stable amorphous fexofenadine hydrochloride
WO2010083360A2 (en) * 2009-01-16 2010-07-22 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
BR112012010597B8 (pt) 2009-11-06 2022-07-19 Basf Se Complexo cristalino, processo para preparar o complexo cristalino, formulação agrícola, método para controlar fungos fitopatogênicos, método para melhorar a saúde de plantas, método para a proteção de material de propagação de planta contra pragas, método para regular o crescimento de plantas e material de propagação de planta revestido
WO2011158262A1 (en) 2010-06-15 2011-12-22 Chemelectiva S.R.L. Polymorphic form of fexofenadine hydrochloride, intermediates and process for its preparation
IT1400965B1 (it) * 2010-06-15 2013-07-05 Dipharma Francis Srl Polimorfi di fexofenadina
US9420872B2 (en) * 2010-08-23 2016-08-23 Jason Bird Apparatus and system for holding game-calling devices
JP2012087100A (ja) * 2010-10-21 2012-05-10 Sumitomo Chemical Co Ltd 形態ｉのフェキソフェナジン一塩酸塩の製造方法
CN104072402B (zh) * 2014-07-16 2016-08-17 昆山龙灯瑞迪制药有限公司 一种新结晶形式的盐酸非索非那定化合物及其制备方法

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US7700779B2 (en) * 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
US20090211514A1 (en) * 2008-02-26 2009-08-27 Lehigh University Single crystal conversion process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135571B2 (en) 1994-05-18 2006-11-14 Aventis Pharmaceuticals, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US7666881B2 (en) 1994-05-18 2010-02-23 Aventis Holdings, Inc. Methods of treating allergic reactions using hydrated forms of antihistaminic piperidine derivatives

Also Published As

Publication number Publication date
US20010012896A1 (en) 2001-08-09
CN1907967A (zh) 2007-02-07
JP2002308850A (ja) 2002-10-23
US20010014741A1 (en) 2001-08-16
FI964565A (fi) 1996-11-14
NO315319B1 (no) 2003-08-18
HU227676B1 (en) 2011-11-28
EP0766668A1 (en) 1997-04-09
ES2176329T3 (es) 2002-12-01
JP4503908B2 (ja) 2010-07-14
US20010025106A1 (en) 2001-09-27
JP2002316978A (ja) 2002-10-31
US20020193600A1 (en) 2002-12-19
EP2354125A1 (en) 2011-08-10
NO964859L (no) 1996-11-15
FI964565A0 (fi) 1996-11-14
DE69527429T2 (de) 2003-03-20
US7662835B2 (en) 2010-02-16
US20070021461A1 (en) 2007-01-25
WO1995031437A1 (en) 1995-11-23
CN1907967B (zh) 2012-07-04
JP4503909B2 (ja) 2010-07-14
CA2189007C (en) 2004-03-02
CN1148849A (zh) 1997-04-30
DK0766668T3 (da) 2002-10-28
CA2449419A1 (en) 1995-11-23
EP0766668B1 (en) 2002-07-17
PT766668E (pt) 2002-11-29
HK1098467A1 (en) 2007-07-20
IL134917A0 (en) 2001-05-20
JP2002255936A (ja) 2002-09-11
US20020193603A1 (en) 2002-12-19
IL113747A0 (en) 1995-08-31
HUT76134A (en) 1997-06-30
JPH10500134A (ja) 1998-01-06
US20080167471A1 (en) 2008-07-10
US20030045721A1 (en) 2003-03-06
JP2002308849A (ja) 2002-10-23
CA2189007A1 (en) 1995-11-23
AU2426595A (en) 1995-12-05
CA2585705A1 (en) 1995-11-23
JP2002255935A (ja) 2002-09-11
HK1137742A1 (en) 2010-08-06
US7135571B2 (en) 2006-11-14
MX9605613A (es) 1998-05-31
US20020193601A1 (en) 2002-12-19
US20080167469A1 (en) 2008-07-10
IL113747A (en) 2001-05-20
AU693892B2 (en) 1998-07-09
CA2449419C (en) 2011-09-06
CN1623985A (zh) 2005-06-08
NO964859D0 (no) 1996-11-15
US20040014976A1 (en) 2004-01-22
HU9603167D0 (en) 1997-01-28
ATE220667T1 (de) 2002-08-15
US7666881B2 (en) 2010-02-23
DE69527429D1 (de) 2002-08-22
EP1178041A1 (en) 2002-02-06
JP2010120969A (ja) 2010-06-03
US20070021462A1 (en) 2007-01-25
US7138524B2 (en) 2006-11-21
JP4503907B2 (ja) 2010-07-14
CA2585705C (en) 2012-04-17

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