HK1137742A1 - Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof - Google Patents

Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof

Info

Publication number
HK1137742A1
HK1137742A1 HK10101357.3A HK10101357A HK1137742A1 HK 1137742 A1 HK1137742 A1 HK 1137742A1 HK 10101357 A HK10101357 A HK 10101357A HK 1137742 A1 HK1137742 A1 HK 1137742A1
Authority
HK
Hong Kong
Prior art keywords
polymorphs
processes
pseudormophs
antihstaminic
piperidine derivatives
Prior art date
Application number
HK10101357.3A
Inventor
Daniel R Henton
Frederick J Mccarty
Susan I Tripp
Jill E Dewitt
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1137742(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of HK1137742A1 publication Critical patent/HK1137742A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas which are useful as antihistamines, antiallergic agents and bronchodilators.
HK10101357.3A 1994-05-18 2010-02-05 Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof HK1137742A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11

Publications (1)

Publication Number Publication Date
HK1137742A1 true HK1137742A1 (en) 2010-08-06

Family

ID=26937420

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07104744.4A HK1098467A1 (en) 1994-05-18 2007-05-04 Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof
HK10101357.3A HK1137742A1 (en) 1994-05-18 2010-02-05 Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07104744.4A HK1098467A1 (en) 1994-05-18 2007-05-04 Processes for preparing anhydrous and hydrate forms of antihstaminic piperidine derivatives, polymorphs and pseudormophs thereof

Country Status (18)

Country Link
US (12) US20010012896A1 (en)
EP (3) EP0766668B1 (en)
JP (7) JPH10500134A (en)
CN (3) CN1148849A (en)
AT (1) ATE220667T1 (en)
AU (1) AU693892B2 (en)
CA (3) CA2449419C (en)
DE (1) DE69527429T2 (en)
DK (1) DK0766668T3 (en)
ES (1) ES2176329T3 (en)
FI (1) FI964565A0 (en)
HK (2) HK1098467A1 (en)
HU (1) HU227676B1 (en)
IL (3) IL113747A (en)
MX (1) MX9605613A (en)
NO (1) NO315319B1 (en)
PT (1) PT766668E (en)
WO (1) WO1995031437A1 (en)

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US20050054616A1 (en) * 2003-07-03 2005-03-10 Judith Aronhime Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
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MXPA06012281A (en) * 2004-04-26 2007-07-18 Teva Pharma Crystalline forms of fexofenadine hydrochloride and processes for their preparation.
ITMI20041143A1 (en) 2004-06-08 2004-09-08 Dipharma Spa FEXOFENADINA POLYMORPHS AND PROCEDURE FOR THEIR PREPARATION
EP1616861A3 (en) * 2004-06-15 2006-02-08 Dipharma S.p.A. A process for the preparation of keto compounds
ITMI20041568A1 (en) * 2004-07-30 2004-10-30 Dipharma Spa "BASE FEXOFENADINA POLYMORPHS"
US20060148851A1 (en) * 2004-09-28 2006-07-06 Shlomit Wizel Fexofenadine crystal form and processes for its preparation thereof
DOP2006000274A (en) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc FEXOFENADINE SUSPENSION FORMULATION
KR20090037930A (en) * 2006-07-11 2009-04-16 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. Controlled-release formulations
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
EP2105134A1 (en) 2008-03-24 2009-09-30 Ranbaxy Laboratories Limited Stable amorphous fexofenadine hydrochloride
US20100183717A1 (en) * 2009-01-16 2010-07-22 Kristin Arnold Controlled-release formulations
KR20120115492A (en) 2009-11-06 2012-10-18 바스프 에스이 Crystalline complexes of 4-hydroxy benzoic acid and selected pesticides
ES2403130B1 (en) 2010-06-15 2014-09-29 Chemelectiva S.R.L. POLYMORPHIC FORM OF FEXOFENADINE CHLORHYDRATE, INTERMEDIATE COMPOUNDS AND PROCEDURE FOR PREPARATION
IT1400965B1 (en) * 2010-06-15 2013-07-05 Dipharma Francis Srl POLYMORFI OF FEXOFENADINA
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Also Published As

Publication number Publication date
US20080167469A1 (en) 2008-07-10
CA2585705A1 (en) 1995-11-23
CA2449419A1 (en) 1995-11-23
US20010025106A1 (en) 2001-09-27
US20070021461A1 (en) 2007-01-25
FI964565A (en) 1996-11-14
DE69527429T2 (en) 2003-03-20
JP4503908B2 (en) 2010-07-14
EP2354125A1 (en) 2011-08-10
ES2176329T3 (en) 2002-12-01
IL113747A0 (en) 1995-08-31
JP2002316978A (en) 2002-10-31
IL134917A0 (en) 2001-05-20
US7662835B2 (en) 2010-02-16
IL134917A (en) 2001-07-24
US20020193603A1 (en) 2002-12-19
AU693892B2 (en) 1998-07-09
US20010012896A1 (en) 2001-08-09
JP4503907B2 (en) 2010-07-14
US20030045721A1 (en) 2003-03-06
US20080167471A1 (en) 2008-07-10
CN1148849A (en) 1997-04-30
US20020193601A1 (en) 2002-12-19
MX9605613A (en) 1998-05-31
CA2189007A1 (en) 1995-11-23
WO1995031437A1 (en) 1995-11-23
JP4503909B2 (en) 2010-07-14
JP2002255935A (en) 2002-09-11
AU2426595A (en) 1995-12-05
US20020193600A1 (en) 2002-12-19
HUT76134A (en) 1997-06-30
CN1907967B (en) 2012-07-04
NO964859L (en) 1996-11-15
US20010014741A1 (en) 2001-08-16
JPH10500134A (en) 1998-01-06
EP1178041A1 (en) 2002-02-06
US7135571B2 (en) 2006-11-14
HK1098467A1 (en) 2007-07-20
CA2449419C (en) 2011-09-06
US7138524B2 (en) 2006-11-21
DK0766668T3 (en) 2002-10-28
NO964859D0 (en) 1996-11-15
US20040014976A1 (en) 2004-01-22
EP0766668A1 (en) 1997-04-09
CN1907967A (en) 2007-02-07
CN1623985A (en) 2005-06-08
NO315319B1 (en) 2003-08-18
US7666881B2 (en) 2010-02-23
HU9603167D0 (en) 1997-01-28
JP2002308849A (en) 2002-10-23
EP0766668B1 (en) 2002-07-17
JP2002255936A (en) 2002-09-11
US20070021462A1 (en) 2007-01-25
ATE220667T1 (en) 2002-08-15
DE69527429D1 (en) 2002-08-22
JP2002308850A (en) 2002-10-23
CA2585705C (en) 2012-04-17
FI964565A0 (en) 1996-11-14
IL113747A (en) 2001-05-20
PT766668E (en) 2002-11-29
HU227676B1 (en) 2011-11-28
JP2010120969A (en) 2010-06-03
CA2189007C (en) 2004-03-02

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