IL133674A0 - Benzimidazole derivatives - Google Patents

Benzimidazole derivatives

Info

Publication number
IL133674A0
IL133674A0 IL13367498A IL13367498A IL133674A0 IL 133674 A0 IL133674 A0 IL 133674A0 IL 13367498 A IL13367498 A IL 13367498A IL 13367498 A IL13367498 A IL 13367498A IL 133674 A0 IL133674 A0 IL 133674A0
Authority
IL
Israel
Prior art keywords
benzimidazole derivatives
benzimidazole
derivatives
Prior art date
Application number
IL13367498A
Other languages
English (en)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL133674A0 publication Critical patent/IL133674A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13367498A 1997-06-27 1998-06-26 Benzimidazole derivatives IL133674A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18769697 1997-06-27
JP7635798 1998-03-25
PCT/JP1998/002885 WO1999000373A1 (fr) 1997-06-27 1998-06-26 Derives de benzimidazole

Publications (1)

Publication Number Publication Date
IL133674A0 true IL133674A0 (en) 2001-04-30

Family

ID=26417500

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13367498A IL133674A0 (en) 1997-06-27 1998-06-26 Benzimidazole derivatives

Country Status (15)

Country Link
US (1) US6420409B1 (fr)
EP (1) EP1020452A4 (fr)
KR (1) KR20010014166A (fr)
CN (1) CN1135224C (fr)
AR (1) AR016108A1 (fr)
AU (1) AU748541B2 (fr)
BR (1) BR9811273A (fr)
CA (1) CA2294505A1 (fr)
HK (1) HK1028246A1 (fr)
HU (1) HUP0002324A3 (fr)
IL (1) IL133674A0 (fr)
RU (1) RU2243968C2 (fr)
TR (1) TR199903277T2 (fr)
TW (1) TW453999B (fr)
WO (1) WO1999000373A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2295239A1 (fr) * 1997-06-27 1999-01-07 Fujisawa Pharmaceutical Co., Ltd. Sulfamides et leur utilisation medicale
WO1999051574A1 (fr) * 1998-04-06 1999-10-14 Fujisawa Pharmaceutical Co., Ltd. Derives d'indole
WO2000028991A1 (fr) * 1998-11-13 2000-05-25 Fujisawa Pharmaceutical Co., Ltd. Remedes contre le syndrome des ovaires polykystiques
WO2000039099A1 (fr) * 1998-12-24 2000-07-06 Fujisawa Pharmaceutical Co., Ltd. Derives de benzimidazole
US6432989B1 (en) 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
US6525067B1 (en) 1999-11-23 2003-02-25 Pfizer Inc Substituted heterocyclic derivatives
EP1149583A3 (fr) * 2000-04-13 2001-11-14 Pfizer Products Inc. Combinaison des antagonistes de la facteur de la liberation de la corticotropin et des secrétagogues de l hormone de croissance
US6821978B2 (en) 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
EP1442042A1 (fr) 2001-11-09 2004-08-04 Schering Corporation Inhibiteurs de la phosphodiesterase v de derives polycycliques de guanine
US20050032854A1 (en) * 2001-12-03 2005-02-10 Kiminori Kawahara Insulin resistance improving agents
US20030181461A1 (en) * 2002-01-25 2003-09-25 Lautt Wilfred Wayne Use of phosphodiesterase antagonists to treat insulin resistance
AU2003223093B2 (en) * 2002-05-03 2010-02-04 Israel Institute For Biological Research Methods and compositions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor
AU2003902860A0 (en) * 2003-06-06 2003-06-26 Daicel Chemical Industries, Ltd Benzimidazole compounds
US20050197376A1 (en) * 2004-03-02 2005-09-08 Fujisawa Pharmaceutical Co. Ltd. Concomitant drugs
EP1983992A4 (fr) * 2006-01-19 2010-08-18 Abbott Lab 2-imino-benzimidazoles
WO2011063339A1 (fr) * 2009-11-23 2011-05-26 Cardioxyl Pharmaceuticals, Inc. Donneurs de nitroxyle destinés au traitement de l'hypertension pulmonaire
CN105919987B (zh) * 2009-12-07 2020-04-03 约翰斯霍普金斯大学 N-酰氧基磺酰胺和n-羟基-n-酰基磺酰胺衍生物及其用途
CA2782248A1 (fr) 2009-12-07 2011-06-16 Cardioxyl Pharmaceuticals, Inc. Derives d'hydroxylamine bis-acylee
JP5990106B2 (ja) * 2011-01-28 2016-09-07 佐藤製薬株式会社 縮環化合物
JP6456520B2 (ja) 2015-12-11 2019-01-23 帝人ファーマ株式会社 アミノアゾール誘導体
WO2017192728A1 (fr) 2016-05-03 2017-11-09 Virginia Commonwealth University Carbones poreux dopés avec des hétéroatomes pour des applications d'énergie propre et leurs procédés de synthèse

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE676196C (de) 1936-08-21 1939-05-30 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von Imidazolverbindungen
US3152142A (en) 1962-05-24 1964-10-06 Dow Chemical Co Benzimidazole compounds
FR2291749A1 (fr) 1974-11-20 1976-06-18 Delalande Sa Nouveaux benzimidazoles acetiques, leur procede de preparation et leur application en therapeutique
JPS51133267A (en) 1975-05-08 1976-11-18 Lilly Co Eli Substituted 11sulphonyl benzimidazole
US4179505A (en) 1977-03-30 1979-12-18 Janssen Pharmaceutica N.V. 5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives
US4243806A (en) 1979-06-13 1981-01-06 Janssen Pharmaceutica N.V. 5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives
GB2053215B (en) 1979-06-25 1983-04-07 May & Baker Ltd Benzimidazole derivatives
JPS625966A (ja) 1985-07-03 1987-01-12 Nippon Shinyaku Co Ltd ベンズイミダゾ−ル誘導体
NZ221729A (en) 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
CA2004911A1 (fr) 1988-12-22 1990-06-22 Mitsuaki Ohta Derives de 4,5,6,7-tetrahydrobenzimidazole
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
WO1991016313A1 (fr) 1990-04-13 1991-10-31 Smithkline Beecham Corporation Benzimidazoles substitues
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5703110A (en) 1990-04-27 1997-12-30 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
RU1836357C (ru) 1990-07-23 1993-08-23 Др.Карл Томэ ГмбХ Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами
DE4023369A1 (de) * 1990-07-23 1992-01-30 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US5602127A (en) 1991-02-06 1997-02-11 Karl Thomae Gmbh (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
SI9210098B (sl) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
US5594003A (en) 1991-02-06 1997-01-14 Dr. Karl Thomae Gmbh Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
DE4224133A1 (de) * 1992-07-22 1994-01-27 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5591762A (en) 1991-02-06 1997-01-07 Dr. Karl Thomae Gmbh Benzimidazoles useful as angiotensin-11 antagonists
US5407835A (en) 1991-07-31 1995-04-18 Abbott Laboratories Reagents and methods for the quantification of amitriptyline or nortriptyline in biological fluids
GB9121776D0 (en) 1991-10-14 1991-11-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives and process for preparation thereof
DE4237557A1 (de) 1992-11-06 1994-05-11 Bayer Ag Substituierte Benzimidazole
JPH0853424A (ja) 1994-08-11 1996-02-27 Kureha Chem Ind Co Ltd ベンズイミダゾールスルホン酸アミド誘導体
GB9423910D0 (en) 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
EP0882718B1 (fr) * 1995-12-28 2005-08-31 Fujisawa Pharmaceutical Co., Ltd. Derives du benzimidazole

Also Published As

Publication number Publication date
CN1135224C (zh) 2004-01-21
HUP0002324A3 (en) 2001-07-30
AU7934698A (en) 1999-01-19
RU2243968C2 (ru) 2005-01-10
CA2294505A1 (fr) 1999-01-07
HK1028246A1 (en) 2001-02-09
HUP0002324A2 (hu) 2001-05-28
EP1020452A4 (fr) 2003-04-02
WO1999000373A1 (fr) 1999-01-07
TW453999B (en) 2001-09-11
US6420409B1 (en) 2002-07-16
WO1999000373A8 (fr) 2000-07-20
AU748541B2 (en) 2002-06-06
AR016108A1 (es) 2001-06-20
BR9811273A (pt) 2000-07-18
CN1268123A (zh) 2000-09-27
KR20010014166A (ko) 2001-02-26
TR199903277T2 (xx) 2000-07-21
EP1020452A1 (fr) 2000-07-19

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