IL133446A0 - Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase - Google Patents
Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferaseInfo
- Publication number
- IL133446A0 IL133446A0 IL13344698A IL13344698A IL133446A0 IL 133446 A0 IL133446 A0 IL 133446A0 IL 13344698 A IL13344698 A IL 13344698A IL 13344698 A IL13344698 A IL 13344698A IL 133446 A0 IL133446 A0 IL 133446A0
- Authority
- IL
- Israel
- Prior art keywords
- farnesyl
- protein transferase
- substituted tricyclic
- novel phenyl
- tricyclic inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87705297A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011509 WO1998057950A1 (en) | 1997-06-17 | 1998-06-15 | Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL133446A0 true IL133446A0 (en) | 2001-04-30 |
Family
ID=25369151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13344698A IL133446A0 (en) | 1997-06-17 | 1998-06-15 | Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0989981A1 (de) |
| JP (1) | JP2002504150A (de) |
| KR (1) | KR20010013945A (de) |
| CN (1) | CN1267292A (de) |
| AU (1) | AU8253798A (de) |
| CA (1) | CA2293549C (de) |
| HU (1) | HUP0003215A2 (de) |
| IL (1) | IL133446A0 (de) |
| NZ (1) | NZ501613A (de) |
| WO (1) | WO1998057950A1 (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA947969B (en) * | 1993-10-15 | 1996-07-12 | Schering Corp | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| ATE210652T1 (de) * | 1993-10-15 | 2001-12-15 | Schering Corp | Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| JP3193725B2 (ja) * | 1995-12-22 | 2001-07-30 | シェーリング コーポレイション | Ｇ―タンパク質機能の阻害および増殖性疾患の処置に有用な三環式アミド |
-
1998
- 1998-06-15 IL IL13344698A patent/IL133446A0/xx unknown
- 1998-06-15 WO PCT/US1998/011509 patent/WO1998057950A1/en not_active Application Discontinuation
- 1998-06-15 KR KR1019997011970A patent/KR20010013945A/ko not_active Application Discontinuation
- 1998-06-15 CN CN98808215A patent/CN1267292A/zh active Pending
- 1998-06-15 CA CA002293549A patent/CA2293549C/en not_active Expired - Fee Related
- 1998-06-15 HU HU0003215A patent/HUP0003215A2/hu unknown
- 1998-06-15 EP EP98932719A patent/EP0989981A1/de not_active Withdrawn
- 1998-06-15 NZ NZ501613A patent/NZ501613A/en unknown
- 1998-06-15 JP JP50450399A patent/JP2002504150A/ja not_active Ceased
- 1998-06-15 AU AU82537/98A patent/AU8253798A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ501613A (en) | 2001-11-30 |
| CA2293549C (en) | 2008-08-05 |
| WO1998057950A1 (en) | 1998-12-23 |
| HUP0003215A2 (hu) | 2001-06-28 |
| KR20010013945A (ko) | 2001-02-26 |
| CN1267292A (zh) | 2000-09-20 |
| AU8253798A (en) | 1999-01-04 |
| EP0989981A1 (de) | 2000-04-05 |
| JP2002504150A (ja) | 2002-02-05 |
| CA2293549A1 (en) | 1998-12-23 |
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