EP1023270A4 - Inhibitoren der farnesyl-protein-transferase - Google Patents

Inhibitoren der farnesyl-protein-transferase

Info

Publication number
EP1023270A4
EP1023270A4 EP98951061A EP98951061A EP1023270A4 EP 1023270 A4 EP1023270 A4 EP 1023270A4 EP 98951061 A EP98951061 A EP 98951061A EP 98951061 A EP98951061 A EP 98951061A EP 1023270 A4 EP1023270 A4 EP 1023270A4
Authority
EP
European Patent Office
Prior art keywords
farnesyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98951061A
Other languages
English (en)
French (fr)
Other versions
EP1023270A1 (de
Inventor
Jeffrey M Bergman
Christopher Dinsmore
Samuel L Graham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9806432.2A external-priority patent/GB9806432D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1023270A1 publication Critical patent/EP1023270A1/de
Publication of EP1023270A4 publication Critical patent/EP1023270A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP98951061A 1997-10-17 1998-10-13 Inhibitoren der farnesyl-protein-transferase Withdrawn EP1023270A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6434297P 1997-10-17 1997-10-17
US64342P 1997-10-17
GBGB9806432.2A GB9806432D0 (en) 1998-03-25 1998-03-25 Inhibitors of farnesyl-protein transferase
GB9806432 1998-03-25
PCT/US1998/021599 WO1999020609A1 (en) 1997-10-17 1998-10-13 Inhibitors of farnesyl-protein transferase

Publications (2)

Publication Number Publication Date
EP1023270A1 EP1023270A1 (de) 2000-08-02
EP1023270A4 true EP1023270A4 (de) 2001-04-18

Family

ID=26313359

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98951061A Withdrawn EP1023270A4 (de) 1997-10-17 1998-10-13 Inhibitoren der farnesyl-protein-transferase

Country Status (4)

Country Link
EP (1) EP1023270A4 (de)
AU (1) AU9695198A (de)
CA (1) CA2306312A1 (de)
WO (1) WO1999020609A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562823B1 (en) 1998-07-02 2003-05-13 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
AU2001227755A1 (en) 2000-01-12 2001-07-24 Merck And Co., Inc. Inhibitors of prenyl-protein transferase
US6534506B2 (en) 2000-04-10 2003-03-18 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US7211595B2 (en) 2000-11-30 2007-05-01 Abbott Laboratories Farnesyltransferase inhibitors
PE20161035A1 (es) 2013-03-15 2016-11-13 Global Blood Therapeutics Inc Compuestos y usos de estos para la modulacion de la hemoglobina
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997036879A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036889A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997036879A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036889A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9920609A1 *

Also Published As

Publication number Publication date
CA2306312A1 (en) 1999-04-29
AU9695198A (en) 1999-05-10
WO1999020609A1 (en) 1999-04-29
EP1023270A1 (de) 2000-08-02

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