EP1023270A4 - Inhibiteurs de farnesyl-proteine transferase - Google Patents

Inhibiteurs de farnesyl-proteine transferase

Info

Publication number
EP1023270A4
EP1023270A4 EP98951061A EP98951061A EP1023270A4 EP 1023270 A4 EP1023270 A4 EP 1023270A4 EP 98951061 A EP98951061 A EP 98951061A EP 98951061 A EP98951061 A EP 98951061A EP 1023270 A4 EP1023270 A4 EP 1023270A4
Authority
EP
European Patent Office
Prior art keywords
farnesyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98951061A
Other languages
German (de)
English (en)
Other versions
EP1023270A1 (fr
Inventor
Jeffrey M Bergman
Christopher Dinsmore
Samuel L Graham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9806432.2A external-priority patent/GB9806432D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1023270A1 publication Critical patent/EP1023270A1/fr
Publication of EP1023270A4 publication Critical patent/EP1023270A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP98951061A 1997-10-17 1998-10-13 Inhibiteurs de farnesyl-proteine transferase Withdrawn EP1023270A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6434297P 1997-10-17 1997-10-17
US64342P 1997-10-17
GB9806432 1998-03-25
GBGB9806432.2A GB9806432D0 (en) 1998-03-25 1998-03-25 Inhibitors of farnesyl-protein transferase
PCT/US1998/021599 WO1999020609A1 (fr) 1997-10-17 1998-10-13 Inhibiteurs de farnesyl-proteine transferase

Publications (2)

Publication Number Publication Date
EP1023270A1 EP1023270A1 (fr) 2000-08-02
EP1023270A4 true EP1023270A4 (fr) 2001-04-18

Family

ID=26313359

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98951061A Withdrawn EP1023270A4 (fr) 1997-10-17 1998-10-13 Inhibiteurs de farnesyl-proteine transferase

Country Status (4)

Country Link
EP (1) EP1023270A4 (fr)
AU (1) AU9695198A (fr)
CA (1) CA2306312A1 (fr)
WO (1) WO1999020609A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1090012A4 (fr) 1998-07-02 2005-04-06 Merck & Co Inc Inhibiteurs de prenyl-proteine transferase
AU2001227755A1 (en) 2000-01-12 2001-07-24 Merck And Co., Inc. Inhibitors of prenyl-protein transferase
US6534506B2 (en) 2000-04-10 2003-03-18 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US7211595B2 (en) 2000-11-30 2007-05-01 Abbott Laboratories Farnesyltransferase inhibitors
SG10201802911RA (en) 2013-03-15 2018-05-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997036879A1 (fr) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibiteurs de transferase de farnesyl-proteine
WO1997036889A1 (fr) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibiteurs de farnesyle-proteine transferase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997036879A1 (fr) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibiteurs de transferase de farnesyl-proteine
WO1997036889A1 (fr) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibiteurs de farnesyle-proteine transferase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9920609A1 *

Also Published As

Publication number Publication date
WO1999020609A1 (fr) 1999-04-29
EP1023270A1 (fr) 2000-08-02
CA2306312A1 (fr) 1999-04-29
AU9695198A (en) 1999-05-10

Similar Documents

Publication Publication Date Title
EP0891350A4 (fr) Inhibiteurs de farnesyle-proteine transferase
EP1011669A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
GB9604311D0 (en) Inhibitors of farnesyl-protein transferase
EP1045844A4 (fr) Inhibiteurs de farnesyl-proteine transferase
EP0891360A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
EP0904080A4 (fr) Inhibiteurs de farnesyle-proteine transferase
EP0880320A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
EP0891349A4 (fr) Inhibiteurs de farnesyl-proteine transferase
EP0891352A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
EP1035852A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
EP1035850A4 (fr) Inhibiteurs de la transferase de la farnesyl-proteine
EP0891335A4 (fr) Inhibiteurs de transferase de farnesyl-proteine
EP0891353A4 (fr) Inhibiteurs de farnesyle-proteine transferase
EP1035849A4 (fr) Inhibiteurs de la transferase de la farnesyl-proteine
EP0959883A4 (fr) Inhibiteurs de la farnesyle-proteine transferase
EP1023270A4 (fr) Inhibiteurs de farnesyl-proteine transferase
EP0877610A4 (fr) Inhibiteurs de farnesyl-proteine transferase
EP0900081A4 (fr) Inhibiteurs de farnesyl-proteine transferase
GB9703014D0 (en) Inhibitors of farnesyl-protein transferase
GB9702212D0 (en) Inhibitors of farnesyl-protein transferase
GB9702211D0 (en) Inhibitors of farnesyl-protein transferase
GB9701624D0 (en) Inhibitors of farnesyl-protein transferase
GB9701589D0 (en) Inhibitors of farnesyl-protein transferase
EP1045843A4 (fr) Inhibiteurs de la farnesyl-proteine transferase
GB9605157D0 (en) Inhibitors of farnesyl-protein transferase

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000517

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

AX Request for extension of the european patent

Free format text: AL PAYMENT 20000517;LT PAYMENT 20000517;LV PAYMENT 20000517;MK PAYMENT 20000517;RO PAYMENT 20000517;SI PAYMENT 20000517

A4 Supplementary search report drawn up and despatched

Effective date: 20010302

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7C 07D 223/10 A, 7C 07D 267/22 B, 7C 07D 281/18 B, 7C 07D 291/00 B, 7C 07D 337/16 B, 7C 07D 487/00 B, 7C 07D 513/00 B, 7C 07D 491/00 B, 7A 61K 31/55 B, 7A 61K 31/495 B, 7A 61P 35/00 B

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20010518