IL133393A0 - Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase - Google Patents
Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferaseInfo
- Publication number
- IL133393A0 IL133393A0 IL13339398A IL13339398A IL133393A0 IL 133393 A0 IL133393 A0 IL 133393A0 IL 13339398 A IL13339398 A IL 13339398A IL 13339398 A IL13339398 A IL 13339398A IL 133393 A0 IL133393 A0 IL 133393A0
- Authority
- IL
- Israel
- Prior art keywords
- farnesyl
- protein transferase
- novel tricyclic
- sulfonamide inhibitors
- tricyclic sulfonamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87705097A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011508 WO1998057949A1 (en) | 1997-06-17 | 1998-06-15 | Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL133393A0 true IL133393A0 (en) | 2001-04-30 |
Family
ID=25369146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13339398A IL133393A0 (en) | 1997-06-17 | 1998-06-15 | Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0989980A1 (en) |
| JP (1) | JP2002507192A (en) |
| KR (1) | KR20010013826A (en) |
| CN (1) | CN1267290A (en) |
| AR (1) | AR012989A1 (en) |
| AU (1) | AU8253698A (en) |
| CA (1) | CA2293358C (en) |
| CO (1) | CO4940475A1 (en) |
| HU (1) | HUP0004627A2 (en) |
| IL (1) | IL133393A0 (en) |
| NZ (1) | NZ501619A (en) |
| PE (1) | PE86199A1 (en) |
| WO (1) | WO1998057949A1 (en) |
| ZA (1) | ZA985218B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6689789B2 (en) | 1997-06-17 | 2004-02-10 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US7517884B2 (en) | 1998-03-30 | 2009-04-14 | Kalypsys Inc. | Sulfonyl-substituted bicyclic compounds as modulators of PPAR |
| US7342016B2 (en) | 2000-08-30 | 2008-03-11 | Schering Corporation | Farnesyl protein transferase inhibitors as antitumor agents |
| HUP0302104A2 (en) * | 2000-11-29 | 2003-09-29 | Schering Corp. | Novel farnesyl protein transferase inhibitors |
| MX2007005205A (en) | 2004-10-29 | 2007-05-11 | Kalypsys Inc | Sulfonyl-substituted bicyclic compounds as modulators of ppar. |
| US7863276B2 (en) | 2005-10-25 | 2011-01-04 | Kalypsys, Inc | Salts of modulators of PPAR and methods of treating metabolic disorders |
| WO2008091863A1 (en) | 2007-01-23 | 2008-07-31 | Kalypsys, Inc. | Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis |
| JP2016508521A (en) * | 2013-02-19 | 2016-03-22 | アイカーン スクール オブ メディスン アット マウント サイナイＩｃａｈｎ Ｓｃｈｏｏｌ ｏｆ Ｍｅｄｉｃｉｎｅ ａｔ Ｍｔ． Ｓｉｎａｉ | Tricyclic heterocycles as antitumor agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU698960B2 (en) * | 1993-10-15 | 1998-11-12 | Schering Corporation | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL117797A0 (en) * | 1995-04-07 | 1996-08-04 | Pharmacopeia Inc | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases and pharmaceutical compositions comprising them |
-
1998
- 1998-06-15 ZA ZA985218A patent/ZA985218B/en unknown
- 1998-06-15 AU AU82536/98A patent/AU8253698A/en not_active Abandoned
- 1998-06-15 WO PCT/US1998/011508 patent/WO1998057949A1/en not_active Application Discontinuation
- 1998-06-15 PE PE1998000508A patent/PE86199A1/en not_active Application Discontinuation
- 1998-06-15 JP JP54752198A patent/JP2002507192A/en active Pending
- 1998-06-15 NZ NZ501619A patent/NZ501619A/en unknown
- 1998-06-15 CA CA002293358A patent/CA2293358C/en not_active Expired - Fee Related
- 1998-06-15 EP EP98932718A patent/EP0989980A1/en not_active Withdrawn
- 1998-06-15 IL IL13339398A patent/IL133393A0/en unknown
- 1998-06-15 KR KR1019997011846A patent/KR20010013826A/en not_active Application Discontinuation
- 1998-06-15 HU HU0004627A patent/HUP0004627A2/en unknown
- 1998-06-15 CN CN98808186A patent/CN1267290A/en active Pending
- 1998-06-16 AR ARP980102859A patent/AR012989A1/en unknown
- 1998-06-16 CO CO98034142A patent/CO4940475A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0004627A2 (en) | 2001-10-28 |
| PE86199A1 (en) | 1999-09-24 |
| NZ501619A (en) | 2002-02-01 |
| JP2002507192A (en) | 2002-03-05 |
| AR012989A1 (en) | 2000-11-22 |
| EP0989980A1 (en) | 2000-04-05 |
| CN1267290A (en) | 2000-09-20 |
| KR20010013826A (en) | 2001-02-26 |
| ZA985218B (en) | 1998-12-15 |
| CA2293358A1 (en) | 1998-12-23 |
| CO4940475A1 (en) | 2000-07-24 |
| WO1998057949A1 (en) | 1998-12-23 |
| CA2293358C (en) | 2008-08-05 |
| AU8253698A (en) | 1999-01-04 |
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