IL133390A0 - Benzo (5, 6) cyclohepta (1, 2b) pyridine derivatives useful for inhibition of farnesyl protein transferase - Google Patents

Benzo (5, 6) cyclohepta (1, 2b) pyridine derivatives useful for inhibition of farnesyl protein transferase

Info

Publication number
IL133390A0
IL133390A0 IL13339098A IL13339098A IL133390A0 IL 133390 A0 IL133390 A0 IL 133390A0 IL 13339098 A IL13339098 A IL 13339098A IL 13339098 A IL13339098 A IL 13339098A IL 133390 A0 IL133390 A0 IL 133390A0
Authority
IL
Israel
Prior art keywords
aryl
alkyl
aralkyl
heteroaryl
protein transferase
Prior art date
Application number
IL13339098A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL133390A0 publication Critical patent/IL133390A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13339098A 1997-06-17 1998-06-15 Benzo (5, 6) cyclohepta (1, 2b) pyridine derivatives useful for inhibition of farnesyl protein transferase IL133390A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87767397A 1997-06-17 1997-06-17
PCT/US1998/011498 WO1998057962A1 (en) 1997-06-17 1998-06-15 Benzo(5,6)cyclohepta(1,2b)pyridine derivatives useful for inhibition of farnesyl protein transferase

Publications (1)

Publication Number Publication Date
IL133390A0 true IL133390A0 (en) 2001-04-30

Family

ID=25370476

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13339098A IL133390A0 (en) 1997-06-17 1998-06-15 Benzo (5, 6) cyclohepta (1, 2b) pyridine derivatives useful for inhibition of farnesyl protein transferase

Country Status (14)

Country Link
EP (1) EP0993460B1 (xx)
JP (1) JP2002504147A (xx)
KR (1) KR20010013828A (xx)
CN (1) CN1172932C (xx)
AT (1) ATE276247T1 (xx)
AU (1) AU753533B2 (xx)
CA (1) CA2293372C (xx)
DE (1) DE69826281T2 (xx)
ES (1) ES2226142T3 (xx)
HK (1) HK1028238A1 (xx)
HU (1) HUP0004806A3 (xx)
IL (1) IL133390A0 (xx)
NZ (1) NZ501615A (xx)
WO (1) WO1998057962A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7645771B2 (en) * 2002-12-13 2010-01-12 Smithkline Beecham Corp. CCR5 antagonists as therapeutic agents
DE10334493B4 (de) * 2003-07-29 2006-01-05 Klingelnberg Gmbh Verfahren zum Fräsen von Spiralkegelrädern
CN111868031B (zh) * 2018-01-19 2023-10-03 有机合成药品工业株式会社 N-烷氧基羰基哌啶衍生物的制备方法及其中间体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
EP0411048A1 (en) * 1988-04-28 1991-02-06 Schering Corporation Novel benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
AU7815398A (en) 1999-01-04
ES2226142T3 (es) 2005-03-16
DE69826281D1 (de) 2004-10-21
ATE276247T1 (de) 2004-10-15
CA2293372C (en) 2009-01-13
KR20010013828A (ko) 2001-02-26
EP0993460A1 (en) 2000-04-19
DE69826281T2 (de) 2005-11-17
CN1267298A (zh) 2000-09-20
HUP0004806A3 (en) 2002-11-28
EP0993460B1 (en) 2004-09-15
HK1028238A1 (en) 2001-02-09
WO1998057962A1 (en) 1998-12-23
CA2293372A1 (en) 1998-12-23
JP2002504147A (ja) 2002-02-05
NZ501615A (en) 2002-02-01
AU753533B2 (en) 2002-10-17
HUP0004806A2 (hu) 2001-10-28
CN1172932C (zh) 2004-10-27

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