DE3889083D1 - Pyrrolophthalazine. - Google Patents

Pyrrolophthalazine.

Info

Publication number
DE3889083D1
DE3889083D1 DE3889083T DE3889083T DE3889083D1 DE 3889083 D1 DE3889083 D1 DE 3889083D1 DE 3889083 T DE3889083 T DE 3889083T DE 3889083 T DE3889083 T DE 3889083T DE 3889083 D1 DE3889083 D1 DE 3889083D1
Authority
DE
Germany
Prior art keywords
aryl
optionally substituted
substituted alkyl
heteroaryl
alkynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3889083T
Other languages
English (en)
Inventor
Michael John Ashton
Andrew William Bridge
Donald Ian Dron
Garry Fenton
David John Lythgoe
Christopher Gregory Newton
David Riddell
Christopher Smith
Keith Alfred James Stuttle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Application granted granted Critical
Publication of DE3889083D1 publication Critical patent/DE3889083D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE3889083T 1987-12-03 1988-12-02 Pyrrolophthalazine. Expired - Lifetime DE3889083D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878728314A GB8728314D0 (en) 1987-12-03 1987-12-03 New compositions of matter

Publications (1)

Publication Number Publication Date
DE3889083D1 true DE3889083D1 (de) 1994-05-19

Family

ID=10627948

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3889083T Expired - Lifetime DE3889083D1 (de) 1987-12-03 1988-12-02 Pyrrolophthalazine.

Country Status (6)

Country Link
US (1) US4960775A (de)
EP (1) EP0319330B1 (de)
JP (1) JPH01186888A (de)
AT (1) ATE104299T1 (de)
DE (1) DE3889083D1 (de)
GB (1) GB8728314D0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018903A1 (en) * 1990-05-25 1991-12-12 Fujisawa Pharmaceutical Co., Ltd. Pyrrolopyridazine compounds
GB0228894D0 (en) * 2002-12-11 2003-01-15 Avecia Ltd Process
TWI695839B (zh) * 2017-11-17 2020-06-11 中央研究院 雙（羥甲基）吡咯并酞嗪混成物、其之製備方法與用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH544763A (de) * 1970-03-26 1974-01-15 Siegfried Ag Verfahren zur Herstellung von Spiro-Additionsprodukten aus N-haltigen Heterocyclen und Maleinimiden
CH644459A5 (de) * 1978-09-29 1984-07-31 Ciba Geigy Ag Verfahren zur herstellung farbphotographischer bilder nach dem silberfarbbleichverfahren.
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
CA1317945C (en) * 1985-12-13 1993-05-18 Ulf Fischer Tricyclic pyridazopyridone derivatives
NO881411L (no) * 1987-04-14 1988-10-17 Bayer Ag Substituerte pyrroler.
EP0294599A3 (de) * 1987-06-12 1990-05-09 F. Hoffmann-La Roche Ag Tricyclische Pyridonderivate

Also Published As

Publication number Publication date
EP0319330A2 (de) 1989-06-07
GB8728314D0 (en) 1988-01-06
US4960775A (en) 1990-10-02
EP0319330B1 (de) 1994-04-13
ATE104299T1 (de) 1994-04-15
JPH01186888A (ja) 1989-07-26
EP0319330A3 (de) 1991-01-16

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Legal Events

Date Code Title Description
8332 No legal effect for de