HUP0004806A3 - Benzo[5,6]cyclohepta[1,2-b]pyridine derivatives useful for inhibition of farnesyl protein transferase and medicaments containing the compounds - Google Patents
Benzo[5,6]cyclohepta[1,2-b]pyridine derivatives useful for inhibition of farnesyl protein transferase and medicaments containing the compoundsInfo
- Publication number
- HUP0004806A3 HUP0004806A3 HU0004806A HUP0004806A HUP0004806A3 HU P0004806 A3 HUP0004806 A3 HU P0004806A3 HU 0004806 A HU0004806 A HU 0004806A HU P0004806 A HUP0004806 A HU P0004806A HU P0004806 A3 HUP0004806 A3 HU P0004806A3
- Authority
- HU
- Hungary
- Prior art keywords
- cyclohepta
- benzo
- inhibition
- compounds
- protein transferase
- Prior art date
Links
- VVJQGUSMDLABEG-UHFFFAOYSA-N 11h-benzo[1,2]cyclohepta[3,4-b]pyridine Chemical class C1=CC2=CC=CN=C2CC2=CC=CC=C21 VVJQGUSMDLABEG-UHFFFAOYSA-N 0.000 title 1
- 102000004357 Transferases Human genes 0.000 title 1
- 108090000992 Transferases Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87767397A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011498 WO1998057962A1 (en) | 1997-06-17 | 1998-06-15 | Benzo(5,6)cyclohepta(1,2b)pyridine derivatives useful for inhibition of farnesyl protein transferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0004806A2 HUP0004806A2 (hu) | 2001-10-28 |
| HUP0004806A3 true HUP0004806A3 (en) | 2002-11-28 |
Family
ID=25370476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0004806A HUP0004806A3 (en) | 1997-06-17 | 1998-06-15 | Benzo[5,6]cyclohepta[1,2-b]pyridine derivatives useful for inhibition of farnesyl protein transferase and medicaments containing the compounds |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0993460B1 (hu) |
| JP (1) | JP2002504147A (hu) |
| KR (1) | KR20010013828A (hu) |
| CN (1) | CN1172932C (hu) |
| AT (1) | ATE276247T1 (hu) |
| AU (1) | AU753533B2 (hu) |
| CA (1) | CA2293372C (hu) |
| DE (1) | DE69826281T2 (hu) |
| ES (1) | ES2226142T3 (hu) |
| HK (1) | HK1028238A1 (hu) |
| HU (1) | HUP0004806A3 (hu) |
| IL (1) | IL133390A0 (hu) |
| NZ (1) | NZ501615A (hu) |
| WO (1) | WO1998057962A1 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05006354A (es) * | 2002-12-13 | 2005-08-26 | Smithkline Beecham Corp | Antagonistas ccr5 como agentes terapeuticos. |
| DE10334493B4 (de) * | 2003-07-29 | 2006-01-05 | Klingelnberg Gmbh | Verfahren zum Fräsen von Spiralkegelrädern |
| EP3741745B1 (en) | 2018-01-19 | 2023-04-26 | Yuki Gosei Kogyo Co., Ltd. | Method for producing n-alkoxycarbonylpiperidine derivative, and intermediate therefor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| ES2056214T3 (es) * | 1988-04-28 | 1994-10-01 | Schering Corp | Compuestos de benzopirido-piperidina, -piperidilideno y -piperazina, composiciones, metodos de preparacion y metodos de uso. |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1998
- 1998-06-15 HU HU0004806A patent/HUP0004806A3/hu unknown
- 1998-06-15 ES ES98926278T patent/ES2226142T3/es not_active Expired - Lifetime
- 1998-06-15 CN CNB988082055A patent/CN1172932C/zh not_active Expired - Fee Related
- 1998-06-15 EP EP98926278A patent/EP0993460B1/en not_active Expired - Lifetime
- 1998-06-15 DE DE69826281T patent/DE69826281T2/de not_active Expired - Lifetime
- 1998-06-15 JP JP50449399A patent/JP2002504147A/ja not_active Ceased
- 1998-06-15 AT AT98926278T patent/ATE276247T1/de not_active IP Right Cessation
- 1998-06-15 WO PCT/US1998/011498 patent/WO1998057962A1/en not_active Application Discontinuation
- 1998-06-15 NZ NZ501615A patent/NZ501615A/en unknown
- 1998-06-15 AU AU78153/98A patent/AU753533B2/en not_active Ceased
- 1998-06-15 CA CA002293372A patent/CA2293372C/en not_active Expired - Fee Related
- 1998-06-15 IL IL13339098A patent/IL133390A0/xx unknown
- 1998-06-15 KR KR1019997011848A patent/KR20010013828A/ko not_active Application Discontinuation
-
2000
- 2000-10-12 HK HK00106503A patent/HK1028238A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1028238A1 (en) | 2001-02-09 |
| CN1267298A (zh) | 2000-09-20 |
| ES2226142T3 (es) | 2005-03-16 |
| NZ501615A (en) | 2002-02-01 |
| JP2002504147A (ja) | 2002-02-05 |
| HUP0004806A2 (hu) | 2001-10-28 |
| KR20010013828A (ko) | 2001-02-26 |
| DE69826281D1 (de) | 2004-10-21 |
| CN1172932C (zh) | 2004-10-27 |
| DE69826281T2 (de) | 2005-11-17 |
| WO1998057962A1 (en) | 1998-12-23 |
| CA2293372C (en) | 2009-01-13 |
| EP0993460B1 (en) | 2004-09-15 |
| EP0993460A1 (en) | 2000-04-19 |
| AU7815398A (en) | 1999-01-04 |
| ATE276247T1 (de) | 2004-10-15 |
| IL133390A0 (en) | 2001-04-30 |
| CA2293372A1 (en) | 1998-12-23 |
| AU753533B2 (en) | 2002-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |