IL133098A - Composition comprising finely divided crystalline particles of budesonide - Google Patents

Composition comprising finely divided crystalline particles of budesonide

Info

Publication number
IL133098A
IL133098A IL13309898A IL13309898A IL133098A IL 133098 A IL133098 A IL 133098A IL 13309898 A IL13309898 A IL 13309898A IL 13309898 A IL13309898 A IL 13309898A IL 133098 A IL133098 A IL 133098A
Authority
IL
Israel
Prior art keywords
budesonide
composition
finely divided
crystalline particles
divided crystalline
Prior art date
Application number
IL13309898A
Other languages
English (en)
Other versions
IL133098A0 (en
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL133098A0 publication Critical patent/IL133098A0/xx
Publication of IL133098A publication Critical patent/IL133098A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL13309898A 1997-05-23 1998-05-15 Composition comprising finely divided crystalline particles of budesonide IL133098A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701956A SE9701956D0 (sv) 1997-05-23 1997-05-23 New composition of matter
PCT/SE1998/000908 WO1998052544A1 (en) 1997-05-23 1998-05-15 Composition comprising finely divided, crystalline particles of budesonide

Publications (2)

Publication Number Publication Date
IL133098A0 IL133098A0 (en) 2001-03-19
IL133098A true IL133098A (en) 2005-03-20

Family

ID=20407079

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13309898A IL133098A (en) 1997-05-23 1998-05-15 Composition comprising finely divided crystalline particles of budesonide

Country Status (28)

Country Link
US (2) US6346523B1 (id)
EP (1) EP1005328B1 (id)
JP (1) JP2001525850A (id)
KR (1) KR100514971B1 (id)
CN (1) CN1146406C (id)
AR (1) AR015820A1 (id)
AT (1) ATE246492T1 (id)
AU (1) AU734763B2 (id)
BR (1) BR9808812A (id)
CA (1) CA2290538C (id)
DE (1) DE69816997T2 (id)
DK (1) DK1005328T3 (id)
EE (1) EE03850B1 (id)
ES (1) ES2205496T3 (id)
HU (1) HUP0002212A3 (id)
ID (1) ID24332A (id)
IL (1) IL133098A (id)
IS (1) IS5254A (id)
NO (1) NO995540D0 (id)
NZ (1) NZ500852A (id)
PL (1) PL336902A1 (id)
PT (1) PT1005328E (id)
SE (1) SE9701956D0 (id)
SK (1) SK158799A3 (id)
TR (1) TR199902880T2 (id)
TW (1) TW518236B (id)
WO (1) WO1998052544A1 (id)
ZA (1) ZA984127B (id)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69633222T2 (de) * 1995-02-24 2005-09-08 Elan Pharma International Ltd. Nanopartikel-dispersionen enthaltende aerosole
EP1263516A1 (en) * 2000-03-03 2002-12-11 Boehringer Ingelheim Pharmaceuticals Inc. Material processing by repeated solvent expansion-contraction
WO2002051381A1 (fr) * 2000-12-26 2002-07-04 Takeda Chemical Industries, Ltd. Substance poreuse et son procede de fabrication
GB0106403D0 (en) * 2001-03-15 2001-05-02 Pharmaceutical Profiles Labelling of dry powder formulations for inhalation
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
EP1423175B1 (en) 2001-08-08 2013-10-02 Brown University Research Foundation Methods for micronization of hydrophobic drugs
DE60211004T2 (de) 2001-10-10 2006-08-31 Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield Pulververarbeitung mit unter druck stehenden gasförmigen fluids
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
JP2007501683A (ja) 2003-05-22 2007-02-01 エラン ファーマ インターナショナル リミテッド γ線照射によるナノ粒子活性物質分散体の滅菌法
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20070020196A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid prepared from a unit dose suspension
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
WO2005088655A1 (en) * 2004-03-12 2005-09-22 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin A magnetoresistive medium
WO2006096906A1 (en) * 2005-03-18 2006-09-21 Nanomaterials Technology Pte Ltd Inhalable drug
US8475845B2 (en) 2005-07-15 2013-07-02 Map Pharmaceuticals, Inc. Method of particle formation
EP1782839A1 (en) 2005-11-03 2007-05-09 Genetic S.p.A. Sterilization process of Glucocorticosteroid by supercritical CO2
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070178051A1 (en) * 2006-01-27 2007-08-02 Elan Pharma International, Ltd. Sterilized nanoparticulate glucocorticosteroid formulations
CA2642579A1 (en) * 2006-02-15 2007-08-23 Tika Lakemedel Ab Sterilization of corticosteroids with reduced mass loss
KR20150041804A (ko) 2007-02-11 2015-04-17 맵 파마슈티컬스, 인코포레이티드 부작용 프로파일을 최소화하면서 편두통의 빠른 완화를 가능하게 하는 ｄｈｅ의 치료적 투여 방법
US20100294986A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Supercritical fluid facilitated particle formation in microfluidic systems
US20100298602A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Systems and methods for microfluidic crystallization
US8574630B2 (en) * 2010-09-22 2013-11-05 Map Pharmaceuticals, Inc. Corticosteroid particles and method of production
CN102975731B (zh) * 2012-04-24 2015-08-12 南车南京浦镇车辆有限公司 轨道车辆司机室骨架与车体的安装结构
WO2021219230A1 (en) 2020-04-30 2021-11-04 Paolo Fiorina Antiviral treatment
KR102567655B1 (ko) 2020-11-13 2023-08-17 주식회사 비츠로이엠 진공커패시터 및 진공커패시터 제조 방법
KR20230072023A (ko) 2021-11-17 2023-05-24 주식회사 비츠로이엠 가변형 진공 커패시터의 나선형 전극 위치 결정구조
KR20230072022A (ko) 2021-11-17 2023-05-24 주식회사 비츠로이엠 가변형 진공 커패시터

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282405C (en) 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
JP2843857B2 (ja) 1988-10-05 1999-01-06 ファルマシア・アンド・アップジョン・カンパニー 反溶剤への沈澱を介する微細分化固体結晶性粉末
GB9001635D0 (en) 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
ES2078447T3 (es) 1990-06-15 1995-12-16 Merck & Co Inc Un procedimiento de cristalizacion para mejorar la estructura y el tamaño de los cristales.
SE9302777D0 (sv) 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
HU0004452D0 (id) * 1991-12-18 2001-01-29 Astra Ab
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles

Also Published As

Publication number Publication date
PT1005328E (pt) 2003-11-28
SE9701956D0 (sv) 1997-05-23
PL336902A1 (en) 2000-07-17
ES2205496T3 (es) 2004-05-01
EE03850B1 (et) 2002-10-15
CA2290538A1 (en) 1998-11-26
ZA984127B (en) 1998-11-23
IS5254A (is) 1999-11-18
KR20010012821A (ko) 2001-02-26
EP1005328B1 (en) 2003-08-06
CN1146406C (zh) 2004-04-21
ATE246492T1 (de) 2003-08-15
EE9900533A (et) 2000-06-15
US20020037257A1 (en) 2002-03-28
KR100514971B1 (ko) 2005-09-15
TR199902880T2 (xx) 2000-02-21
DE69816997T2 (de) 2004-07-22
WO1998052544A1 (en) 1998-11-26
NO995540L (no) 1999-11-12
AU734763B2 (en) 2001-06-21
NO995540D0 (no) 1999-11-12
HUP0002212A3 (en) 2001-04-28
NZ500852A (en) 2001-07-27
JP2001525850A (ja) 2001-12-11
US6346523B1 (en) 2002-02-12
DE69816997D1 (de) 2003-09-11
HUP0002212A2 (hu) 2000-12-28
BR9808812A (pt) 2000-07-18
CN1257424A (zh) 2000-06-21
AU7680098A (en) 1998-12-11
CA2290538C (en) 2007-01-02
EP1005328A1 (en) 2000-06-07
ID24332A (id) 2000-07-13
SK158799A3 (en) 2000-05-16
IL133098A0 (en) 2001-03-19
TW518236B (en) 2003-01-21
AR015820A1 (es) 2001-05-30
US6468994B2 (en) 2002-10-22
DK1005328T3 (da) 2003-11-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees