IL132012A - Transformed benzamides and their use in the preparation of immune modulators - Google Patents
Transformed benzamides and their use in the preparation of immune modulatorsInfo
- Publication number
- IL132012A IL132012A IL13201299A IL13201299A IL132012A IL 132012 A IL132012 A IL 132012A IL 13201299 A IL13201299 A IL 13201299A IL 13201299 A IL13201299 A IL 13201299A IL 132012 A IL132012 A IL 132012A
- Authority
- IL
- Israel
- Prior art keywords
- group
- formula
- atoms
- chain
- denotes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843793A DE19843793C2 (de) | 1998-09-24 | 1998-09-24 | Substituierte Benzamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL132012A0 IL132012A0 (en) | 2001-03-19 |
| IL132012A true IL132012A (en) | 2004-02-19 |
Family
ID=7882078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13201299A IL132012A (en) | 1998-09-24 | 1999-09-23 | Transformed benzamides and their use in the preparation of immune modulators |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6080742A (ko) |
| EP (1) | EP0989121B1 (ko) |
| JP (1) | JP2000095761A (ko) |
| KR (1) | KR20000023339A (ko) |
| CN (1) | CN1126741C (ko) |
| AR (1) | AR021814A1 (ko) |
| AT (1) | ATE309987T1 (ko) |
| AU (1) | AU750919B2 (ko) |
| BR (1) | BR9906070A (ko) |
| CA (1) | CA2283021A1 (ko) |
| CO (1) | CO5160263A1 (ko) |
| CZ (1) | CZ295496B6 (ko) |
| DE (2) | DE19843793C2 (ko) |
| DK (1) | DK0989121T3 (ko) |
| ES (1) | ES2251143T3 (ko) |
| HK (1) | HK1026211A1 (ko) |
| HU (1) | HUP9903216A3 (ko) |
| IL (1) | IL132012A (ko) |
| NO (1) | NO312671B1 (ko) |
| NZ (1) | NZ337531A (ko) |
| PE (1) | PE20001050A1 (ko) |
| PL (1) | PL194897B1 (ko) |
| RU (1) | RU2221783C2 (ko) |
| SI (1) | SI0989121T1 (ko) |
| SK (1) | SK283316B6 (ko) |
| UY (1) | UY25712A1 (ko) |
| ZA (1) | ZA996133B (ko) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10002509A1 (de) * | 2000-01-21 | 2001-07-26 | Gruenenthal Gmbh | Substituierte Glutarimide |
| WO2001070688A2 (de) * | 2000-03-20 | 2001-09-27 | Grünenthal GmbH | N-(2,6-dioxo-piperidin-3-yl) benzamide und ihre verwendung als immunomodulatoren |
| US20050118137A1 (en) * | 2000-07-19 | 2005-06-02 | Chih-Ping Liu | Method of treatment using interferon-tau |
| US20050118138A1 (en) * | 2000-07-19 | 2005-06-02 | Chih-Ping Liu | Method of treatment using interferon-tau |
| US7431920B2 (en) * | 2000-07-19 | 2008-10-07 | Pepgen Corporation | Method of treating IL-10 deficiency |
| US20050226845A1 (en) * | 2004-03-10 | 2005-10-13 | Chih-Ping Liu | Method of treatment using interferon-tau |
| US20050201981A1 (en) * | 2004-03-10 | 2005-09-15 | Chih-Ping Liu | Method of optimizing treatment with interferon-tau |
| US20040247565A1 (en) * | 2000-07-19 | 2004-12-09 | Chih-Ping Liu | Method of treatment using interferon-tau |
| US20050084478A1 (en) * | 2000-10-17 | 2005-04-21 | Chih-Ping Liu | Combination therapy using interferon-tau |
| EP1199074A1 (en) * | 2000-09-15 | 2002-04-24 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production |
| EP1188438A1 (en) * | 2000-09-15 | 2002-03-20 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production |
| CA2439410C (en) * | 2001-02-27 | 2011-09-06 | William D. Figg | Analogs of thalidomide as potential angiogenesis inhibitors |
| US6479493B1 (en) | 2001-08-23 | 2002-11-12 | Cell Pathways, Inc. | Methods for treatment of type I diabetes |
| WO2003037365A1 (en) * | 2001-11-01 | 2003-05-08 | The Johns Hopkins University | Methods and compositions for treating vascular leak using hepatocyte growth factor |
| DE10163595A1 (de) * | 2001-12-21 | 2003-08-07 | Gruenenthal Gmbh | In 3-Position heterocyclisch substituierte Piperidin-2,6-dione |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| US7973057B2 (en) | 2003-09-17 | 2011-07-05 | The United States Of America As Represented By The Department Of Health And Human Services | Thalidomide analogs |
| US20080025948A1 (en) * | 2004-03-10 | 2008-01-31 | Chih-Ping Liu | Methods of Treatment Using Interferon-Tau |
| US20060078942A1 (en) * | 2004-03-10 | 2006-04-13 | Pepgen Corporation | Method of treatment using interferon-tau |
| DE102004026703A1 (de) * | 2004-05-28 | 2005-12-29 | Grünenthal GmbH | Verfahren zur Herstellung von in 3-Position heterocyclisch substituierten Piperidin-2,6-dionen |
| CA2648216C (en) * | 2006-04-13 | 2016-06-07 | Michael Gutschow | Tetrahalogenated compounds useful as inhibitors of angiogenesis |
| JP5658138B2 (ja) | 2008-04-23 | 2015-01-21 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 代謝障害の処置のためのカルボキサミド化合物 |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| KR102316961B1 (ko) * | 2020-01-29 | 2021-10-26 | 프라비바이오 주식회사 | 면역억제제로서의 벤젠 유도체의 면역억제용 약학적 조성물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1545672B2 (de) * | 1965-05-08 | 1974-11-07 | Chemie Gruenenthal Gmbh, 5190 Stolberg | Dikarbonsäureimidderivate und Verfahren zu ihrer Herstellung |
-
1998
- 1998-09-24 DE DE19843793A patent/DE19843793C2/de not_active Expired - Fee Related
-
1999
- 1999-08-27 NZ NZ337531A patent/NZ337531A/xx not_active IP Right Cessation
- 1999-09-03 EP EP99117319A patent/EP0989121B1/de not_active Expired - Lifetime
- 1999-09-03 ES ES99117319T patent/ES2251143T3/es not_active Expired - Lifetime
- 1999-09-03 AT AT99117319T patent/ATE309987T1/de active
- 1999-09-03 DK DK99117319T patent/DK0989121T3/da active
- 1999-09-03 DE DE59912795T patent/DE59912795D1/de not_active Expired - Lifetime
- 1999-09-03 SI SI9930863T patent/SI0989121T1/sl unknown
- 1999-09-15 UY UY25712A patent/UY25712A1/es unknown
- 1999-09-17 AR ARP990104701A patent/AR021814A1/es unknown
- 1999-09-17 PE PE1999000942A patent/PE20001050A1/es not_active Application Discontinuation
- 1999-09-21 KR KR1019990040635A patent/KR20000023339A/ko not_active Application Discontinuation
- 1999-09-21 CO CO99059817A patent/CO5160263A1/es unknown
- 1999-09-22 JP JP11269084A patent/JP2000095761A/ja not_active Withdrawn
- 1999-09-22 AU AU48861/99A patent/AU750919B2/en not_active Ceased
- 1999-09-22 CA CA002283021A patent/CA2283021A1/en not_active Abandoned
- 1999-09-22 HU HU9903216A patent/HUP9903216A3/hu unknown
- 1999-09-23 CZ CZ19993386A patent/CZ295496B6/cs not_active IP Right Cessation
- 1999-09-23 SK SK1308-99A patent/SK283316B6/sk not_active IP Right Cessation
- 1999-09-23 IL IL13201299A patent/IL132012A/en not_active IP Right Cessation
- 1999-09-23 ZA ZA9906133A patent/ZA996133B/xx unknown
- 1999-09-23 RU RU99120663/04A patent/RU2221783C2/ru not_active IP Right Cessation
- 1999-09-23 CN CN99120232A patent/CN1126741C/zh not_active Expired - Fee Related
- 1999-09-23 NO NO19994626A patent/NO312671B1/no not_active IP Right Cessation
- 1999-09-23 PL PL335555A patent/PL194897B1/pl not_active IP Right Cessation
- 1999-09-23 BR BR9906070-1A patent/BR9906070A/pt not_active IP Right Cessation
- 1999-09-24 US US09/405,180 patent/US6080742A/en not_active Expired - Lifetime
-
2000
- 2000-09-01 HK HK00105496A patent/HK1026211A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |