IL130605A0 - 3-aryl-2- (1-substituted-4-piperidinyl)-1 (1-DI)oxo-3H-benzo¬D¾-isothiazole derivatives their preparation and their use as modulators of neurotransmitter function - Google Patents

3-aryl-2- (1-substituted-4-piperidinyl)-1 (1-DI)oxo-3H-benzo¬D¾-isothiazole derivatives their preparation and their use as modulators of neurotransmitter function

Info

Publication number
IL130605A0
IL130605A0 IL13060597A IL13060597A IL130605A0 IL 130605 A0 IL130605 A0 IL 130605A0 IL 13060597 A IL13060597 A IL 13060597A IL 13060597 A IL13060597 A IL 13060597A IL 130605 A0 IL130605 A0 IL 130605A0
Authority
IL
Israel
Prior art keywords
piperidinyl
benzo
modulators
oxo
aryl
Prior art date
Application number
IL13060597A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL130605A0 publication Critical patent/IL130605A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13060597A 1996-12-23 1997-11-13 3-aryl-2- (1-substituted-4-piperidinyl)-1 (1-DI)oxo-3H-benzo¬D¾-isothiazole derivatives their preparation and their use as modulators of neurotransmitter function IL130605A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77486696A 1996-12-23 1996-12-23
PCT/US1997/021178 WO1998028295A1 (en) 1996-12-23 1997-11-13 3-aryl-2-(1-substituted-4-piperidinyl)-1(1-di)oxo-3h-benzo[d]-isothiazole derivatives, their preparation and their use as modulators of neurotransmitter function

Publications (1)

Publication Number Publication Date
IL130605A0 true IL130605A0 (en) 2000-06-01

Family

ID=25102528

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13060597A IL130605A0 (en) 1996-12-23 1997-11-13 3-aryl-2- (1-substituted-4-piperidinyl)-1 (1-DI)oxo-3H-benzo¬D¾-isothiazole derivatives their preparation and their use as modulators of neurotransmitter function

Country Status (17)

Country Link
EP (1) EP0956287B1 (ja)
JP (1) JP3282827B2 (ja)
KR (1) KR20000062283A (ja)
AR (1) AR009440A1 (ja)
AT (1) ATE247111T1 (ja)
AU (1) AU716689B2 (ja)
BR (1) BR9714432A (ja)
CA (1) CA2273181C (ja)
DE (1) DE69724148T2 (ja)
DK (1) DK0956287T3 (ja)
ES (1) ES2200205T3 (ja)
HU (1) HUP9904071A3 (ja)
IL (1) IL130605A0 (ja)
NO (1) NO993085L (ja)
PT (1) PT956287E (ja)
WO (1) WO1998028295A1 (ja)
ZA (1) ZA9711337B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1393351B1 (it) * 2009-03-16 2012-04-20 Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2509797C2 (de) * 1975-03-06 1985-07-18 Dr. Karl Thomae Gmbh, 7950 Biberach Phthalimidine, deren physiologisch verträgliche Säureadditionssalze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
AT345806B (de) * 1975-03-06 1978-10-10 Thomae Gmbh Dr K Verfahren zur herstellung neuer substituierter arylalkylamine und deren salze
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors

Also Published As

Publication number Publication date
ES2200205T3 (es) 2004-03-01
AR009440A1 (es) 2000-04-12
AU716689B2 (en) 2000-03-02
DE69724148D1 (de) 2003-09-18
HUP9904071A2 (hu) 2000-05-28
ATE247111T1 (de) 2003-08-15
JP3282827B2 (ja) 2002-05-20
KR20000062283A (ko) 2000-10-25
DE69724148T2 (de) 2004-06-09
NO993085D0 (no) 1999-06-22
CA2273181A1 (en) 1998-07-02
CA2273181C (en) 2004-01-20
BR9714432A (pt) 2000-05-02
ZA9711337B (en) 1998-06-23
NO993085L (no) 1999-08-20
AU5358898A (en) 1998-07-17
DK0956287T3 (da) 2003-11-24
JP2001520641A (ja) 2001-10-30
EP0956287B1 (en) 2003-08-13
HUP9904071A3 (en) 2000-07-28
WO1998028295A1 (en) 1998-07-02
EP0956287A1 (en) 1999-11-17
PT956287E (pt) 2003-11-28

Similar Documents

Publication Publication Date Title
EP1066053B8 (en) Hib/dtpa vaccine composition and methods of preparation
PL340589A1 (en) Derivatives of thienepyrimidine and thienepyridine useful as anticarcinogenic agents
AU4540697A (en) Photo-stable cosmetic and pharmaceutical formulations containing UV-filters
AU5708398A (en) Printable adhesive composition and methods of preparation
IL116066A0 (en) Controlled release caffeine composition and its preparation
EP0925175A4 (en) FORMULATIONS CONTAINING MALEIMIDE AND USES THEREOF
AU2091499A (en) Permeable compositions and methods for their preparation
HUP9904121A3 (en) Oral delayed immediate release formulation and method of preparation therefor
AU6681198A (en) Abrasion-resistant ink compositions and methods of use
AU4108097A (en) Microballoons-containing composition of polydimethylsiloxane
PL338614A1 (en) O-substituted derivatives of hydroxyenmarone as anticarcinogenic and antinetastic agents
EP0950081A4 (en) ESTERIFIED COLOPHANES WITH RESISTANT COLORS AND THEIR PREPARATION
AU2578997A (en) Use of anthocyanidin and anthocyanidin derivatives
AU3191397A (en) Oxazolone derivatives and their use as anti-(helicobacter pylori) agent
AP9600866A0 (en) Benzamine derivative compositions containing said derivative and use thereof
AU9622998A (en) Isoxindigos useful as colorants and preparation thereof
ZA9811795B (en) New n-phenylamide and n-pyridyamide derivatives methods of preparing them and pharmaceutical compositions containing them
IL121691A0 (en) N-benzylazolium derivatives their preparation and compositions containing them
IL130605A0 (en) 3-aryl-2- (1-substituted-4-piperidinyl)-1 (1-DI)oxo-3H-benzo¬D¾-isothiazole derivatives their preparation and their use as modulators of neurotransmitter function
AU4106196A (en) Methods for use of novel lyoprotectants and instant kit formulations for radiopharmaceuticals using the same
AU7377298A (en) Methods and compositions for use of (iso)eugenol methyltransferase
ZA9811762B (en) Fully and partially saturated benzo¬c¾quinolizine derivatives their preparations and use as 5alpha-reductases inhibitors
AUPO982097A0 (en) Methods and compositions for use therein
AU1724697A (en) Novel aminophenol derivatives and their use
AU1268099A (en) Sanitary bag holder and combination of bag and holder