IL128999A0 - Hedgehog interacting proteins and uses related thereto - Google Patents

Hedgehog interacting proteins and uses related thereto

Info

Publication number
IL128999A0
IL128999A0 IL12899997A IL12899997A IL128999A0 IL 128999 A0 IL128999 A0 IL 128999A0 IL 12899997 A IL12899997 A IL 12899997A IL 12899997 A IL12899997 A IL 12899997A IL 128999 A0 IL128999 A0 IL 128999A0
Authority
IL
Israel
Prior art keywords
hedgehog
interacting proteins
proteins
uses related
hedgehog interacting
Prior art date
Application number
IL12899997A
Other languages
English (en)
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of IL128999A0 publication Critical patent/IL128999A0/xx

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
    • G06F13/38—Information transfer, e.g. on bus
    • G06F13/42—Bus transfer protocol, e.g. handshake; Synchronisation
    • G06F13/4204—Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus
    • G06F13/4234—Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus being a memory bus
    • G06F13/4243—Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus being a memory bus with synchronous protocol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL12899997A 1996-09-20 1997-09-19 Hedgehog interacting proteins and uses related thereto IL128999A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2615596P 1996-09-20 1996-09-20
PCT/US1997/016741 WO1998012326A1 (en) 1996-09-20 1997-09-19 Hedgehog interacting proteins and uses related thereto

Publications (1)

Publication Number Publication Date
IL128999A0 true IL128999A0 (en) 2000-02-17

Family

ID=21830211

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12899997A IL128999A0 (en) 1996-09-20 1997-09-19 Hedgehog interacting proteins and uses related thereto
IL128999A IL128999A (en) 1996-09-20 1999-03-15 Proteins that interact with the HEDGEHOG gene and its uses
IL181578A IL181578A (en) 1996-09-20 2007-02-26 Antibodies which are specifically immunoreactive with hedgehog interacting proteins and a hybridoma producing such antibodies

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL128999A IL128999A (en) 1996-09-20 1999-03-15 Proteins that interact with the HEDGEHOG gene and its uses
IL181578A IL181578A (en) 1996-09-20 2007-02-26 Antibodies which are specifically immunoreactive with hedgehog interacting proteins and a hybridoma producing such antibodies

Country Status (11)

Country Link
US (3) US6514724B1 (de)
EP (1) EP0935656B1 (de)
JP (1) JP4083810B2 (de)
AT (1) ATE335819T1 (de)
AU (1) AU742972B2 (de)
CA (1) CA2266429C (de)
DE (1) DE69736484T2 (de)
DK (1) DK0935656T3 (de)
ES (1) ES2278396T3 (de)
IL (3) IL128999A0 (de)
WO (1) WO1998012326A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999000117A2 (en) 1997-06-27 1999-01-07 Ontogeny, Inc. Neuroprotective methods and reagents
US7144997B2 (en) 1997-07-24 2006-12-05 Curis, Inc. Vertebrate embryonic patterning-inducing proteins, compositions and uses related therto
US6639051B2 (en) 1997-10-20 2003-10-28 Curis, Inc. Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
WO1999029854A1 (en) 1997-12-08 1999-06-17 Ontogeny, Inc. Human patched genes and proteins, and uses related thereto
US20030166132A1 (en) * 1998-08-26 2003-09-04 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
ATE404583T1 (de) 1998-11-02 2008-08-15 Curis Inc Funktionelle antagonisten von hedgehog-aktivität
US6884770B1 (en) 1998-11-06 2005-04-26 Curis, Inc. Methods and compositions for treating or preventing peripheral neuropathies
WO2000074706A1 (en) * 1999-06-08 2000-12-14 Lorantis Limited Therapeutic use of an inhibitor of a hedgehog or a hedgehog-related signalling pathway
US7517870B2 (en) * 2004-12-03 2009-04-14 Fondazione Telethon Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization
CA2650338C (en) * 2006-04-27 2013-04-16 Illinois Tool Works Inc. Pan chiller system with single state coolant
KR101771714B1 (ko) * 2008-05-30 2017-08-25 제넨테크, 인크. 변이체 ｈｈｉｐ1 단백질 및 방법 및 그의 용도
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
AU2016323806A1 (en) * 2015-09-16 2018-05-10 La Jolla Nanomedical A cellular activity targeted nanoparticle system and methods of producing the nanoparticle system
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2023211805A1 (en) * 2022-04-26 2023-11-02 The Regents Of The University Of California Hhip-fc fusion proteins and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US5789543A (en) * 1993-12-30 1998-08-04 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins and uses related thereto
WO1995018856A1 (en) * 1993-12-30 1995-07-13 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing hedgehog-like proteins
CA2201887C (en) * 1994-10-07 2009-04-14 Matthew P. Scott Patched genes and their use
US6281332B1 (en) * 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides

Also Published As

Publication number Publication date
DK0935656T3 (da) 2006-12-11
DE69736484T2 (de) 2007-03-29
US6514724B1 (en) 2003-02-04
US20070054290A1 (en) 2007-03-08
EP0935656B1 (de) 2006-08-09
JP2001501468A (ja) 2001-02-06
WO1998012326A1 (en) 1998-03-26
AU4489297A (en) 1998-04-14
IL181578A (en) 2010-12-30
US7585671B2 (en) 2009-09-08
AU742972B2 (en) 2002-01-17
DE69736484D1 (de) 2006-09-21
ATE335819T1 (de) 2006-09-15
IL181578A0 (en) 2007-07-04
ES2278396T3 (es) 2007-08-01
JP4083810B2 (ja) 2008-04-30
IL128999A (en) 2008-03-20
CA2266429C (en) 2010-05-18
CA2266429A1 (en) 1998-03-26
EP0935656A1 (de) 1999-08-18
US7115394B2 (en) 2006-10-03
US20030143595A1 (en) 2003-07-31

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