IL128564A0 - Lentiviral vectors - Google Patents
Lentiviral vectorsInfo
- Publication number
- IL128564A0 IL128564A0 IL12856497A IL12856497A IL128564A0 IL 128564 A0 IL128564 A0 IL 128564A0 IL 12856497 A IL12856497 A IL 12856497A IL 12856497 A IL12856497 A IL 12856497A IL 128564 A0 IL128564 A0 IL 128564A0
- Authority
- IL
- Israel
- Prior art keywords
- lentiviral vectors
- vector particles
- provirus
- letiviruses
- ltr
- Prior art date
Links
- 239000013598 vector Substances 0.000 title abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 1
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
- 230000001177 retroviral effect Effects 0.000 abstract 1
- 230000002463 transducing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
- C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Mushroom Cultivation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9621680.9A GB9621680D0 (en) | 1996-10-17 | 1996-10-17 | Lentiviral vectors |
| PCT/GB1997/002858 WO1998017816A1 (en) | 1996-10-17 | 1997-10-17 | Lentiviral vectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL128564A0 true IL128564A0 (en) | 2000-01-31 |
Family
ID=10801598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12856497A IL128564A0 (en) | 1996-10-17 | 1997-10-17 | Lentiviral vectors |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6235522B1 (xx) |
| EP (1) | EP0939827B1 (xx) |
| JP (1) | JP2001502903A (xx) |
| KR (1) | KR20000049250A (xx) |
| CN (1) | CN1195864C (xx) |
| AT (1) | ATE520783T1 (xx) |
| AU (1) | AU737801B2 (xx) |
| BG (1) | BG103334A (xx) |
| CA (1) | CA2268271A1 (xx) |
| CZ (1) | CZ137299A3 (xx) |
| GB (2) | GB9621680D0 (xx) |
| HU (1) | HUP0000442A3 (xx) |
| IL (1) | IL128564A0 (xx) |
| NO (1) | NO991742D0 (xx) |
| NZ (1) | NZ334522A (xx) |
| PL (1) | PL332876A1 (xx) |
| WO (1) | WO1998017816A1 (xx) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6924123B2 (en) * | 1996-10-29 | 2005-08-02 | Oxford Biomedica (Uk) Limited | Lentiviral LTR-deleted vector |
| KR100556864B1 (ko) | 1997-05-13 | 2006-03-10 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 렌티바이러스-기원 유전자 전달 벡터 |
| FI112580B (fi) | 1997-06-27 | 2003-12-15 | Nokia Corp | Kutsunsiirron reititys peruspalvelukohtaisesti |
| WO1999015641A1 (en) | 1997-09-24 | 1999-04-01 | The Regents Of The University Of California | Non-primate lentiviral vectors and packaging systems |
| US5994136A (en) * | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| GB9803351D0 (en) | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| EP1088086A4 (en) | 1998-06-24 | 2003-01-08 | Musc Found For Res Dev | TISSUE-SPECIFIC AND TARGET RNA-SPECIFIC RIBOZYMS |
| US6958226B1 (en) | 1998-09-11 | 2005-10-25 | The Children's Medical Center Corp. | Packaging cells comprising codon-optimized gagpol sequences and lacking lentiviral accessory proteins |
| EP1169480A4 (en) | 1999-04-14 | 2005-02-02 | Musc Found For Res Dev | TOXIC AGENTS AND RIBOZYMES SPECIFIC TO TISSUE AND SPECIFIC PATHOGENS |
| US6271359B1 (en) | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| US7250299B1 (en) | 1999-04-29 | 2007-07-31 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| EP1083230A1 (en) * | 1999-09-10 | 2001-03-14 | Academisch Medisch Centrum Amsterdam | Viral replicons and viruses dependent on inducing agents |
| ES2306670T3 (es) | 1999-10-22 | 2008-11-16 | Sanofi Pasteur Limited | Procedimiento de induccion y/o intensificacion de la respuesta inmunitaria frente a antigenos tumorales. |
| US6656706B2 (en) | 1999-12-23 | 2003-12-02 | The United States Of America As Represented By The Department Of Health And Human Services | Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes |
| EP1702983A3 (en) | 2000-04-13 | 2007-01-10 | Medical University of South Carolina | Tissue-specific and pathogen-specific toxic agents, ribozymes, DNAzymes and antisense oligonucleotides and methods of use thereof |
| ATE346925T1 (de) | 2000-05-10 | 2006-12-15 | Sanofi Pasteur Ltd | Durch mage minigene kodierte immunogene polypeptide und ihre verwendungen |
| WO2001090391A2 (en) | 2000-05-19 | 2001-11-29 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution |
| CA2426647A1 (en) * | 2000-10-20 | 2002-05-02 | Whitehead Institute For Biomedical Research | Expression vectors and uses thereof |
| US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
| US6712612B1 (en) | 2000-12-12 | 2004-03-30 | Genecure Llc | Safe and stable retroviral helper cell line and related compositions and methods |
| US20040235169A1 (en) * | 2001-04-20 | 2004-11-25 | Evans Ronald M. | Inducible expression of transfected genes |
| US20030039636A1 (en) * | 2001-05-01 | 2003-02-27 | Genetix Pharmaceuticals, Inc. | Novel self-inactivating (SIN) lentiviral vectors |
| ATE527347T1 (de) | 2001-08-02 | 2011-10-15 | Inst Clayton De La Rech | Verfahren und zusammensetzungen im zusammenhang mit verbesserten lentivirusvektor- produktionssystemen |
| AU2002343458B2 (en) | 2001-10-02 | 2008-03-20 | Institut Clayton De La Recherche | Methods and compositions relating to restricted expression lentiviral vectors and their applications |
| EP2348119B1 (en) | 2002-02-01 | 2017-04-26 | Oxford BioMedica (UK) Limited | Multicistronic lentiviral vector |
| AU2003223527B2 (en) | 2002-04-09 | 2009-01-15 | Sanofi Pasteur Limited | Modified CEA nucleic acid and expression vectors |
| KR101002955B1 (ko) * | 2002-04-26 | 2010-12-21 | 인스티튜트 클레이톤 드 라 리쎄르셰 | 개선된 키메라 당단백질 및 슈도타입 렌티바이러스 벡터 |
| US20050014166A1 (en) * | 2002-11-22 | 2005-01-20 | Institut Clayton De La Recherche | Compositions and systems for the regulation of genes |
| WO2005030927A2 (en) * | 2003-09-23 | 2005-04-07 | Uab Research Foundation | Methods and compositions for in vivo inflammation monitoring |
| US8562970B2 (en) * | 2003-10-08 | 2013-10-22 | Sanofi Pasteur Limited | Modified CEA/B7 vector |
| CN1980955A (zh) * | 2004-04-29 | 2007-06-13 | 北卡罗来纳-查佩尔山大学 | 增强细胞粘连特性的方法和组合物 |
| US20060292159A1 (en) * | 2005-06-08 | 2006-12-28 | Ranscht Barbara E | Methods for the inhibition of neovascularization and cancer metastasis |
| GB201202516D0 (en) | 2012-02-13 | 2012-03-28 | Ucl Business Plc | Materials and methods relating to packaging cell lines |
| WO2013184209A1 (en) | 2012-06-04 | 2013-12-12 | Ludwig Institute For Cancer Research Ltd. | Mif for use in methods of treating subjects with a neurodegenerative disorder |
| KR101554678B1 (ko) | 2012-10-19 | 2015-09-21 | 영남대학교 산학협력단 | 식물 바이러스를 이용한 식물체 형질전환을 위한 유전자 전달 시스템 및 이의 용도 |
| DK3889173T5 (da) | 2013-02-15 | 2024-08-05 | Bioverativ Therapeutics Inc | Optimeret faktor viii-gen |
| KR102156290B1 (ko) * | 2013-03-13 | 2020-09-15 | 쫑 리 | 미세소포 및 이를 생산하는 방법 |
| EP3160478A4 (en) | 2014-06-30 | 2018-05-16 | Bioverativ Therapeutics Inc. | Optimized factor ix gene |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| EP3411478B1 (en) | 2016-02-01 | 2022-06-08 | Bioverativ Therapeutics Inc. | Optimized factor viii genes |
| WO2017180587A2 (en) | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| PE20191031A1 (es) | 2016-10-12 | 2019-08-05 | Bioverativ Usa Inc | ANTICUERPOS ANTI-C1s Y METODOS DE USO DE LOS MISMOS |
| KR102431830B1 (ko) | 2016-11-07 | 2022-08-16 | 주식회사 뉴라클사이언스 | 서열 유사성을 가진 항-패밀리 19, 멤버 a5 항체 및 그것의 사용 방법 |
| EP3645563A4 (en) | 2017-06-27 | 2021-03-17 | Neuracle Science Co., Ltd | ANTI-FAM19A5 ANTIBODIES AND USES THEREOF |
| US11746149B2 (en) | 2017-06-27 | 2023-09-05 | Neuracle Science Co., Ltd. | Use of anti-family with sequence similarity 19, member A5 antibodies for the treatment of glaucoma |
| KR20220031738A (ko) | 2017-06-27 | 2022-03-11 | 주식회사 뉴라클사이언스 | 암 치료를 위한 항-fam19a5 항체의 용도 |
| WO2019003159A1 (en) | 2017-06-27 | 2019-01-03 | Neuracle Science Co., Ltd. | USE OF ANTI-FAM19A5 ANTIBODIES FOR THE TREATMENT OF FIBROSIS |
| EP3648776A4 (en) | 2017-07-06 | 2021-04-07 | The Medical College of Wisconsin, Inc. | NEW IN-VITRO AND IN-VIVO ENRICHMENT STRATEGY AGAINST LYMPHOCYTE FROM VECTOR-TRANSDUCED HSC FOR THE TREATMENT OF DISEASES |
| CN111527105B (zh) | 2017-10-11 | 2024-10-25 | 美国比奥维拉迪维股份有限公司 | 诱导补体活性的方法 |
| JP2021512126A (ja) | 2018-02-01 | 2021-05-13 | バイオベラティブ セラピューティクス インコーポレイテッド | 第ｖｉｉｉ因子を発現するレンチウイルスベクターの使用 |
| AU2019259798A1 (en) | 2018-04-24 | 2020-11-12 | Neuracle Science Co., Ltd. | Use of anti-family with sequence similarity 19, member A5 antibodies for the treatment of neuropathic pain |
| EP3784695B1 (en) | 2018-04-27 | 2023-08-09 | The Medical College of Wisconsin, Inc. | Use of lentivector-transduced t-rapa cells for amelioration of lysosomal storage disorders |
| CN112119091B (zh) | 2018-05-10 | 2025-01-03 | 纽洛可科学有限公司 | 抗序列相似家族19成员a5的抗体及其使用方法 |
| US11884729B2 (en) | 2018-06-29 | 2024-01-30 | ApitBio, Inc | Anti-L1CAM antibodies and uses thereof |
| CN119185536A (zh) | 2018-10-16 | 2024-12-27 | 纽洛可科学有限公司 | 抗fam19a5抗体的用途 |
| AU2019379325B2 (en) | 2018-11-16 | 2025-04-24 | Genexine, Inc. | Method of treating a tumor with a combination of IL-7 protein and an immune checkpoint inhibitor |
| CN113396223A (zh) | 2018-12-06 | 2021-09-14 | 比奥维拉迪维治疗股份有限公司 | 表达因子ix的慢病毒载体的用途 |
| KR20200071198A (ko) | 2018-12-10 | 2020-06-19 | 네오이뮨텍, 인코퍼레이티드 | Nrf2 발현 조절 기반 T 세포 항암면역치료법 |
| AU2018454784A1 (en) * | 2018-12-25 | 2021-08-05 | National Center Of Neurology And Psychiatry | Method for inducing muscular cells using cells in spot urine |
| US12247070B2 (en) | 2018-12-27 | 2025-03-11 | Neuracle Science Co., Ltd. | Use of anti-FAM19A5 antibodies for treating atherosclerosis |
| EP3906260A4 (en) | 2019-01-02 | 2022-08-31 | Neuracle Science Co., Ltd | SEQUENCE-LIKE ANTI-FAMILY ANTIBODIES 19, MEMBER A5 AND METHOD OF USE THEREOF |
| CN115279896A (zh) | 2019-09-30 | 2022-11-01 | 比奥维拉迪维治疗股份有限公司 | 慢病毒载体配制品 |
| KR20220150274A (ko) | 2020-01-13 | 2022-11-10 | 네오이뮨텍, 인코퍼레이티드 | Il-7 단백질과 이중특이적 항체의 조합물을 사용한 종양의 치료 방법 |
| WO2021151001A1 (en) | 2020-01-22 | 2021-07-29 | Outpace Bio, Inc. | Chimeric polypeptides |
| EP4093752A2 (en) | 2020-01-22 | 2022-11-30 | Outpace Bio, Inc. | Chimeric polypeptides |
| AU2021217373A1 (en) | 2020-02-05 | 2022-08-04 | Neoimmunetech, Inc. | Method of treating a solid tumor with a combination of an IL-7 protein and CAR-bearing immune cells |
| KR20230074703A (ko) | 2020-06-24 | 2023-05-31 | 바이오버라티브 테라퓨틱스 인크. | 유리 인자 viii을 상기 단백질이 발현되도록 변형된 렌티바이러스 벡터의 제제로부터 제거하는 방법 |
| EP4232566A1 (en) | 2020-10-22 | 2023-08-30 | Lyell Immunopharma, Inc. | Chimeric activation receptors |
| US20230398184A1 (en) | 2020-10-26 | 2023-12-14 | Neoimmunetech, Inc. | Methods of inducing stem cell mobilization |
| WO2022094475A1 (en) | 2020-11-02 | 2022-05-05 | Neoimmunetech, Inc. | Use of interleukin-7 for the treatment of coronavirus |
| JP2023549112A (ja) | 2020-11-05 | 2023-11-22 | ネオイミューンテック， インコーポレイテッド | Ｉｌ－７タンパク質とヌクレオチドワクチンの組み合わせで腫瘍を治療する方法 |
| WO2022251644A1 (en) | 2021-05-28 | 2022-12-01 | Lyell Immunopharma, Inc. | Nr4a3-deficient immune cells and uses thereof |
| US20230052243A1 (en) | 2021-06-02 | 2023-02-16 | Lyell Immunopharma, Inc. | Nr4a-deficient cells expressing c-jun and uses thereof |
| IL311725A (en) | 2021-09-30 | 2024-05-01 | Bioverativ Therapeutics Inc | Nucleic acids encoding factor VIII polypeptides with reduced immunogenicity |
| JP2024540411A (ja) | 2021-11-08 | 2024-10-31 | プロジェントス・セラピューティクス・インコーポレイテッド | 血小板由来成長因子受容体（ｐｄｇｆｒ）アルファ阻害剤及びその使用 |
| US20250099542A1 (en) | 2021-12-30 | 2025-03-27 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of il-7 protein and vegf antagonist |
| CN119866224A (zh) | 2022-07-28 | 2025-04-22 | 加拿大干细胞技术公司 | 编码连接抗原的多核苷酸以及其用途 |
| WO2024102722A1 (en) | 2022-11-07 | 2024-05-16 | Neoimmunetech, Inc. | Methods of treating a tumor with an unmethylated mgmt promoter |
| WO2025010272A1 (en) | 2023-07-03 | 2025-01-09 | Neoimmunetech, Inc. | Heterodimeric fc molecules and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5604114A (en) * | 1986-05-20 | 1997-02-18 | Dana-Farber Cancer Institute | Cis-acting repression sequences, cis-acting antirepression sequences, vectors, methods of preparation and use |
| EP0588914A1 (en) * | 1991-05-29 | 1994-03-30 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Eukaryotic expression vectors with regulation of rna processing |
| WO1995030755A1 (en) | 1994-05-10 | 1995-11-16 | Hisamitsu Pharmaceutical Co., Inc. | Recombinant human immunodeficiency virus vector and process for producing the same |
| WO1995032300A1 (en) | 1994-05-23 | 1995-11-30 | University Of Medicine & Dentistry Of New Jersey | Selective biological destruction of tumor cells |
| US5693508A (en) * | 1994-11-08 | 1997-12-02 | Chang; Lung-Ji | Retroviral expression vectors containing MoMLV/CMV-IE/HIV-TAR chimeric long terminal repeats |
| AU5103996A (en) * | 1995-03-09 | 1996-10-02 | Bavarian Nordic Research Institute A/S | Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy |
| GB9510272D0 (en) * | 1995-05-22 | 1995-07-19 | Isis Innovation | Retroviral vectors |
| WO1997048277A1 (en) * | 1996-06-20 | 1997-12-24 | The Salk Institute For Biological Studies | Modular assembly retroviral vectors and uses thereof |
-
1996
- 1996-10-17 GB GBGB9621680.9A patent/GB9621680D0/en active Pending
-
1997
- 1997-10-17 NZ NZ334522A patent/NZ334522A/en not_active IP Right Cessation
- 1997-10-17 EP EP97909437A patent/EP0939827B1/en not_active Expired - Lifetime
- 1997-10-17 WO PCT/GB1997/002858 patent/WO1998017816A1/en not_active Ceased
- 1997-10-17 IL IL12856497A patent/IL128564A0/xx unknown
- 1997-10-17 US US09/284,011 patent/US6235522B1/en not_active Expired - Lifetime
- 1997-10-17 AU AU47123/97A patent/AU737801B2/en not_active Expired
- 1997-10-17 AT AT97909437T patent/ATE520783T1/de not_active IP Right Cessation
- 1997-10-17 HU HU0000442A patent/HUP0000442A3/hu unknown
- 1997-10-17 PL PL97332876A patent/PL332876A1/xx unknown
- 1997-10-17 CA CA002268271A patent/CA2268271A1/en not_active Abandoned
- 1997-10-17 CN CNB971988838A patent/CN1195864C/zh not_active Expired - Lifetime
- 1997-10-17 JP JP10519087A patent/JP2001502903A/ja not_active Ceased
- 1997-10-17 CZ CZ991372A patent/CZ137299A3/cs unknown
- 1997-10-17 KR KR1019990703355A patent/KR20000049250A/ko not_active Ceased
- 1997-10-17 GB GB9903117A patent/GB2331522B/en not_active Expired - Lifetime
-
1999
- 1999-04-13 NO NO991742A patent/NO991742D0/no not_active Application Discontinuation
- 1999-04-14 BG BG103334A patent/BG103334A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU737801B2 (en) | 2001-08-30 |
| KR20000049250A (ko) | 2000-07-25 |
| BG103334A (en) | 2000-06-30 |
| CA2268271A1 (en) | 1998-04-30 |
| PL332876A1 (en) | 1999-10-25 |
| AU4712397A (en) | 1998-05-15 |
| JP2001502903A (ja) | 2001-03-06 |
| NO991742L (no) | 1999-04-13 |
| EP0939827A1 (en) | 1999-09-08 |
| US6235522B1 (en) | 2001-05-22 |
| GB2331522A (en) | 1999-05-26 |
| HUP0000442A2 (hu) | 2000-06-28 |
| GB9903117D0 (en) | 1999-04-07 |
| CZ137299A3 (cs) | 1999-07-14 |
| GB2331522B (en) | 2001-05-23 |
| ATE520783T1 (de) | 2011-09-15 |
| CN1234075A (zh) | 1999-11-03 |
| WO1998017816A1 (en) | 1998-04-30 |
| HUP0000442A3 (en) | 2001-09-28 |
| EP0939827B1 (en) | 2011-08-17 |
| NZ334522A (en) | 2001-11-30 |
| NO991742D0 (no) | 1999-04-13 |
| HK1018481A1 (en) | 1999-12-24 |
| CN1195864C (zh) | 2005-04-06 |
| GB9621680D0 (en) | 1996-12-11 |
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