IL127417A0 - Indoline derivatives useful as 5-HT-2C receptor antagonists - Google Patents
Indoline derivatives useful as 5-HT-2C receptor antagonistsInfo
- Publication number
- IL127417A0 IL127417A0 IL12741797A IL12741797A IL127417A0 IL 127417 A0 IL127417 A0 IL 127417A0 IL 12741797 A IL12741797 A IL 12741797A IL 12741797 A IL12741797 A IL 12741797A IL 127417 A0 IL127417 A0 IL 127417A0
- Authority
- IL
- Israel
- Prior art keywords
- receptor antagonists
- derivatives useful
- indoline derivatives
- indoline
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
| PCT/EP1997/003156 WO1997048699A1 (en) | 1996-06-20 | 1997-06-16 | Indoline derivatives useful as 5-ht-2c receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL127417A0 true IL127417A0 (en) | 1999-10-28 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12741797A IL127417A0 (en) | 1996-06-20 | 1997-06-16 | Indoline derivatives useful as 5-HT-2C receptor antagonists |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (de) |
| EP (1) | EP0912554B1 (de) |
| JP (1) | JP2000512306A (de) |
| KR (1) | KR20000022045A (de) |
| CN (1) | CN1229408A (de) |
| AP (2) | AP9801410A0 (de) |
| AR (1) | AR008243A1 (de) |
| AT (1) | ATE228514T1 (de) |
| AU (1) | AU718597B2 (de) |
| BG (1) | BG103089A (de) |
| BR (1) | BR9709911A (de) |
| CA (1) | CA2258240A1 (de) |
| CO (1) | CO4890847A1 (de) |
| CZ (1) | CZ420598A3 (de) |
| DE (1) | DE69717449T2 (de) |
| DZ (1) | DZ2250A1 (de) |
| EA (1) | EA001780B1 (de) |
| ES (1) | ES2187783T3 (de) |
| GB (1) | GB9612883D0 (de) |
| HU (1) | HUP9903439A3 (de) |
| ID (1) | ID19433A (de) |
| IL (1) | IL127417A0 (de) |
| MA (1) | MA24214A1 (de) |
| NO (1) | NO985972L (de) |
| NZ (1) | NZ333229A (de) |
| OA (1) | OA10944A (de) |
| PE (1) | PE86698A1 (de) |
| PL (1) | PL330796A1 (de) |
| SK (1) | SK282706B6 (de) |
| TR (1) | TR199802661T2 (de) |
| TW (1) | TW382015B (de) |
| WO (1) | WO1997048699A1 (de) |
| ZA (1) | ZA975415B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3030899A (en) * | 1998-02-25 | 1999-09-15 | Smithkline Beecham Plc | Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| MXPA04005151A (es) | 2001-11-28 | 2004-08-11 | Upjohn Co | Compuestos terapeuticos. |
| AU2003217817A1 (en) * | 2002-03-04 | 2003-09-22 | Pharmacia And Upjohn Company | Pyridinyloxy derivatives as 5-ht receptor ligands |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| CA2749783A1 (en) | 2009-01-16 | 2010-07-22 | Massachusetts Institute Of Technology | Diagnosis and treatment of autism spectrum disorders |
| WO2012080497A2 (en) | 2010-12-17 | 2012-06-21 | Glaxo Group Limited | Methods of treatment and prevention of eye diseases |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (en) | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| AU4704693A (en) * | 1992-08-20 | 1994-03-15 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT-2C and 5HT-2B antagonists |
| GB9313913D0 (en) * | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| BR9607016A (pt) * | 1995-02-02 | 1997-10-28 | Smithkline Beecham Plc | Derivados de indol como antagonísta de receptor 5-ht |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/en not_active Application Discontinuation
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Application Discontinuation
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 EP EP97928224A patent/EP0912554B1/de not_active Expired - Lifetime
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-16 CA CA002258240A patent/CA2258240A1/en not_active Abandoned
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
-
1998
- 1998-12-18 NO NO985972A patent/NO985972L/no unknown
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
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