IL127331A0 - Peptide-based vaccine for influenza - Google Patents

Peptide-based vaccine for influenza

Info

Publication number
IL127331A0
IL127331A0 IL12733198A IL12733198A IL127331A0 IL 127331 A0 IL127331 A0 IL 127331A0 IL 12733198 A IL12733198 A IL 12733198A IL 12733198 A IL12733198 A IL 12733198A IL 127331 A0 IL127331 A0 IL 127331A0
Authority
IL
Israel
Prior art keywords
epitopes
influenza
epitope
influenza virus
hla molecules
Prior art date
Application number
IL12733198A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL12733198A priority Critical patent/IL127331A0/xx
Publication of IL127331A0 publication Critical patent/IL127331A0/xx
Priority to EP10003160A priority patent/EP2204187B1/en
Priority to AU14066/00A priority patent/AU766883B2/en
Priority to ES10003160T priority patent/ES2389611T3/es
Priority to JP2000584919A priority patent/JP2002531415A/ja
Priority to BR9915811-6A priority patent/BR9915811A/pt
Priority to NZ511918A priority patent/NZ511918A/en
Priority to CA2352454A priority patent/CA2352454C/en
Priority to EP99972929A priority patent/EP1135159A2/en
Priority to AT10003160T priority patent/ATE556719T1/de
Priority to PCT/IL1999/000640 priority patent/WO2000032228A2/en
Priority to US09/856,920 priority patent/US6740325B1/en
Priority to KR1020017006639A priority patent/KR100703571B1/ko
Priority to DK10003160.8T priority patent/DK2204187T3/da
Priority to HK02102105.6A priority patent/HK1040620A1/zh
Priority to PT10003160T priority patent/PT2204187E/pt
Priority to IL14336799A priority patent/IL143367A0/xx
Priority to IL143367A priority patent/IL143367A/en
Priority to US10/846,548 priority patent/US7192595B2/en
Priority to US11/672,429 priority patent/US7514086B2/en
Priority to HK10111907.7A priority patent/HK1145448B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
IL12733198A 1998-11-30 1998-11-30 Peptide-based vaccine for influenza IL127331A0 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IL12733198A IL127331A0 (en) 1998-11-30 1998-11-30 Peptide-based vaccine for influenza
IL14336799A IL143367A0 (en) 1998-11-30 1999-11-28 Peptide based vaccine for influenza
EP99972929A EP1135159A2 (en) 1998-11-30 1999-11-28 Peptide-based vaccine for influenza
PCT/IL1999/000640 WO2000032228A2 (en) 1998-11-30 1999-11-28 Peptide-based vaccine for influenza
ES10003160T ES2389611T3 (es) 1998-11-30 1999-11-28 Vacuna contra la gripe humana que contiene cuatro péptidos de influenza
JP2000584919A JP2002531415A (ja) 1998-11-30 1999-11-28 ペプチドベースのインフルエンザ用ワクチン
BR9915811-6A BR9915811A (pt) 1998-11-30 1999-11-28 Vacina a base de peptìdeo para influenza
NZ511918A NZ511918A (en) 1998-11-30 1999-11-28 Flu vaccine comprising four synthetic peptide epitopes
CA2352454A CA2352454C (en) 1998-11-30 1999-11-28 Peptide-based vaccine for influenza
EP10003160A EP2204187B1 (en) 1998-11-30 1999-11-28 Human flu vaccine containing four influenza peptides
AT10003160T ATE556719T1 (de) 1998-11-30 1999-11-28 Impfstoff gegen menschliche influenza, der vier peptide aus influenza enthält
AU14066/00A AU766883B2 (en) 1998-11-30 1999-11-28 Peptide-based vaccine for influenza
US09/856,920 US6740325B1 (en) 1998-11-30 1999-11-28 Peptide-based vaccine for influenza
KR1020017006639A KR100703571B1 (ko) 1998-11-30 1999-11-28 인플루엔자에 대한 펩티드-기초 백신
DK10003160.8T DK2204187T3 (da) 1998-11-30 1999-11-28 Human influenzavaccine indeholdende fire influenzapeptider
HK02102105.6A HK1040620A1 (zh) 1998-11-30 1999-11-28 治疗流感的肽基疫苗
PT10003160T PT2204187E (pt) 1998-11-30 1999-11-28 Vacina contra a gripe humana contendo quatro péptidos de influenza
IL143367A IL143367A (en) 1998-11-30 2001-05-24 Influenza vaccine based on peptides
US10/846,548 US7192595B2 (en) 1998-11-30 2004-05-17 Peptide-based vaccine for influenza
US11/672,429 US7514086B2 (en) 1998-11-30 2007-02-07 Peptide-based vaccine for influenza
HK10111907.7A HK1145448B (en) 1998-11-30 2010-12-21 Human flu vaccine containing four influenza peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12733198A IL127331A0 (en) 1998-11-30 1998-11-30 Peptide-based vaccine for influenza

Publications (1)

Publication Number Publication Date
IL127331A0 true IL127331A0 (en) 1999-09-22

Family

ID=11072200

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12733198A IL127331A0 (en) 1998-11-30 1998-11-30 Peptide-based vaccine for influenza
IL14336799A IL143367A0 (en) 1998-11-30 1999-11-28 Peptide based vaccine for influenza
IL143367A IL143367A (en) 1998-11-30 2001-05-24 Influenza vaccine based on peptides

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL14336799A IL143367A0 (en) 1998-11-30 1999-11-28 Peptide based vaccine for influenza
IL143367A IL143367A (en) 1998-11-30 2001-05-24 Influenza vaccine based on peptides

Country Status (15)

Country Link
US (3) US6740325B1 (enExample)
EP (2) EP1135159A2 (enExample)
JP (1) JP2002531415A (enExample)
KR (1) KR100703571B1 (enExample)
AT (1) ATE556719T1 (enExample)
AU (1) AU766883B2 (enExample)
BR (1) BR9915811A (enExample)
CA (1) CA2352454C (enExample)
DK (1) DK2204187T3 (enExample)
ES (1) ES2389611T3 (enExample)
HK (1) HK1040620A1 (enExample)
IL (3) IL127331A0 (enExample)
NZ (1) NZ511918A (enExample)
PT (1) PT2204187E (enExample)
WO (1) WO2000032228A2 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL127331A0 (en) * 1998-11-30 1999-09-22 Yeda Res & Dev Peptide-based vaccine for influenza
AU2002223398A1 (en) * 2000-08-10 2002-04-08 Tsinghua University A vaccine for influenza virus and its preparation
FI20031536A0 (fi) * 2003-10-20 2003-10-20 Biotie Therapies Oyj Korkean affiniteetin ligandit influenssavirukselle ja menetelmät niiden valmistamiseen
DK1692265T3 (da) 2003-11-04 2011-11-21 Univ Tulane Fremgangsmåde til hindring af en virus-celle-fusion ved hæmning af fusionsinitieringsområdets funktion i RNA-vira med klasse 1-membranfusogene envelopeproteiner
GB0716992D0 (en) * 2007-08-31 2007-10-10 Immune Targeting Systems Its L Influenza antigen delivery vectors and constructs
WO2006074303A2 (en) * 2005-01-05 2006-07-13 Philadelphia Health And Education Corporation Delivery vehicles, bioactive substances and viral vaccines
MY157941A (en) 2005-01-19 2016-08-15 Vaxinnate Corp Compositions of pathogen-associated molecular patterns and methods of use
FI20060200A0 (fi) * 2005-04-20 2006-02-27 Glykos Finland Oy Menetelmä ihmisen influenssaviruksen sialihahappositoumisspesifisyyden analysoimiseksi
MX2007015105A (es) * 2005-06-01 2008-03-18 Variation Biotechnologies Inc Formulacion de vacuna de influenza a base de peptido.
US7871626B2 (en) * 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
US7468187B2 (en) * 2005-10-18 2008-12-23 Iowa State University Research Foundation, Inc. Canine influenza virus and related compositions and methods of use
WO2007051036A2 (en) * 2005-10-26 2007-05-03 Protelix, Inc. Influenza combinatorial antigen vaccine
US9533036B2 (en) * 2005-11-07 2017-01-03 Microvax, Llc Methods for generating immune responses to influenza antigens with a secretable CD40L fusion protein
AU2006322907B2 (en) * 2005-12-06 2012-08-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Improved influenza vaccine
HUE049580T2 (hu) * 2006-01-27 2020-09-28 Seqirus Uk Ltd Hemagglutinint és mátrixfehérjéket tartalmazó, influenza elleni oltóanyagok
GB0613977D0 (en) 2006-02-07 2006-08-23 Peptcell Ltd Peptide sequences and compositions
ES2534332T3 (es) * 2006-03-07 2015-04-21 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
US20080208486A1 (en) * 2006-03-23 2008-08-28 Jari Natunen Integrated System, Device and Use Thereof
US8222204B2 (en) 2006-05-03 2012-07-17 The Administrators of the Tulane Educational Fund and Autoimmune Technologies, LLC Influenza inhibiting compositions and methods
WO2008002663A2 (en) * 2006-06-28 2008-01-03 The Board Of Trustees Of The Leland Stanford Junior University Immunogenic protein constructs
FI20060946A0 (fi) * 2006-10-26 2006-10-26 Glykos Finland Oy Influenssaviruksen nukleiinihappoja ja peptidejä
EP2139908A4 (en) 2007-03-12 2011-02-16 Antigen Express Inc REMOVAL OF PROTEIN Li INVOLVED IN Li-RNAi CONSTRUCTIONS IN ANTICANCER IMMUNOTHERAPY
JP5654345B2 (ja) 2007-08-02 2015-01-14 ビオンドヴァックス ファーマシューティカルズ リミテッド 多量体マルチエピトープインフルエンザワクチン
CA2721246A1 (en) 2008-04-18 2009-10-22 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
CA2721800A1 (en) 2008-04-21 2009-10-29 Nanobio Corporation Nanoemulsion influenza vaccine
JP2011519834A (ja) * 2008-04-25 2011-07-14 インスティチュート フォー システムズ バイオロジー フラジェリンポリペプチドワクチン
WO2009135152A2 (en) 2008-05-02 2009-11-05 University Of Rochester Arrayed detector system for measurement of influenza immune response
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
WO2011005772A1 (en) 2009-07-06 2011-01-13 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
ES2573427T3 (es) 2009-07-06 2016-06-07 Variation Biotechnologies Inc. Procedimientos para preparar vesículas y formulaciones producidas a partir de las mismas
CA2840079C (en) 2010-07-06 2018-07-03 Variation Biotechnologies Inc. Compositions and methods for treating influenza
WO2012097346A1 (en) 2011-01-13 2012-07-19 Variation Biotechnologies, Inc. Compositions and methods for treating viral infections
CN107296792B (zh) 2011-01-13 2021-07-27 变异生物技术公司 囊泡及由其产生之制剂的制备方法
WO2012114323A1 (en) 2011-02-22 2012-08-30 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
CA2840982C (en) 2011-07-06 2022-06-07 Vira BITKO Human respiratory syncytial virus vaccine
WO2013028738A1 (en) 2011-08-22 2013-02-28 Nanobio Corporation Herpes simplex virus nanoemulsion vaccine
EP2780350B1 (en) 2011-11-18 2019-03-06 Variation Biotechnologies Inc. Synthetic derivatives of mpl and uses thereof
CA2894442C (en) 2012-01-12 2020-01-21 Variation Biotechnologies Inc. Compositions and methods for treating viral infections
US20150079077A1 (en) 2012-01-27 2015-03-19 Variation Biotechnologies, Inc. Methods and compositions for therapeutic agents
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
KR20140099828A (ko) 2013-02-05 2014-08-13 닛토덴코 가부시키가이샤 점막 투여용 백신 조성물
EP2762152A1 (en) 2013-02-05 2014-08-06 Nitto Denko Corporation WT1 peptide cancer vaccine composition for transdermal administration
CN103961306A (zh) 2013-02-05 2014-08-06 日东电工株式会社 经皮给予用疫苗组合物
EP3662927A3 (en) 2013-02-05 2020-10-21 Nitto Denko Corporation Vaccine composition
RU2697443C2 (ru) 2013-02-05 2019-08-14 Нитто Денко Корпорейшн Препарат противораковой вакцины, содержащий пептид wt1, в форме ленты трансдермального введения
US10206985B2 (en) 2013-02-05 2019-02-19 Nitto Denko Corporation WT1 peptide cancer vaccine composition for mucosal administration
RU2014102948A (ru) * 2013-02-05 2015-08-10 Нитто Денко Корпорейшн Вакцинная композиция для мукозального введения
CN103961698A (zh) 2013-02-05 2014-08-06 日东电工株式会社 经皮或粘膜给予用疫苗组合物
CA2841016A1 (en) 2013-02-05 2014-08-05 Nitto Denko Corporation Wt1 peptide cancer vaccine composition for transdermal administration
US20140220100A1 (en) 2013-02-05 2014-08-07 Nitto Denko Corporation Vaccine composition for transdermal administration
RU2531235C2 (ru) 2013-02-15 2014-10-20 Общество с ограниченной ответственностью "Универсальные БиоСистемы" (ООО "УБС") Поливалентная вакцина против гриппа на основе гибридного белка
CN103901202B (zh) * 2014-04-04 2015-08-12 中国人民解放军成都军区疾病预防控制中心 基于共有表位甲型流感病毒抗体通用型竞争性elisa检测方法
US10925936B2 (en) 2014-09-03 2021-02-23 Nitto Denko Corporation Vaccine pharmaceutical composition for cell-mediated immunity containing bisphosphonates
EP3189852B1 (en) 2014-09-03 2021-04-07 Nitto Denko Corporation Bisphosphonate-containing pharmaceutical vaccine composition for humoral immunity
US11278616B2 (en) 2015-08-06 2022-03-22 Nitto Denko Corporation Immunity induction promoting composition, and vaccine pharmaceutical composition
WO2018126060A1 (en) * 2016-12-28 2018-07-05 Invvax, Inc. Influenza vaccines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61904A (en) 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
IL101639A0 (en) 1992-04-17 1992-12-30 Yeda Res & Dev Recombinant influenza vaccines
AU3036597A (en) * 1996-05-21 1997-12-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for using peptide complexes/major histocompatibility complex to obtain or purify antigen-specific t cells and to stimulate t cells
IL127331A0 (en) * 1998-11-30 1999-09-22 Yeda Res & Dev Peptide-based vaccine for influenza

Also Published As

Publication number Publication date
EP1135159A2 (en) 2001-09-26
KR100703571B1 (ko) 2007-04-05
EP2204187A1 (en) 2010-07-07
IL143367A0 (en) 2002-04-21
US6740325B1 (en) 2004-05-25
US20050002954A1 (en) 2005-01-06
CA2352454A1 (en) 2000-06-08
HK1040620A1 (zh) 2002-06-21
WO2000032228A3 (en) 2000-10-05
DK2204187T3 (da) 2012-08-20
JP2002531415A (ja) 2002-09-24
CA2352454C (en) 2013-02-05
US7192595B2 (en) 2007-03-20
BR9915811A (pt) 2001-08-21
US20070122424A1 (en) 2007-05-31
NZ511918A (en) 2003-08-29
AU766883B2 (en) 2003-10-23
EP2204187B1 (en) 2012-05-09
AU1406600A (en) 2000-06-19
IL143367A (en) 2006-09-05
US7514086B2 (en) 2009-04-07
HK1145448A1 (en) 2011-04-21
ES2389611T3 (es) 2012-10-29
KR20010089512A (ko) 2001-10-06
PT2204187E (pt) 2012-08-10
ATE556719T1 (de) 2012-05-15
WO2000032228A2 (en) 2000-06-08

Similar Documents

Publication Publication Date Title
IL127331A0 (en) Peptide-based vaccine for influenza
JP2002531415A5 (enExample)
Liu et al. High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity
Schild et al. Fine specificity of cytotoxic T lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide.
SE9704545D0 (sv) Novel compounds
DK1036059T3 (da) Adamantanderivater
DK0528859T3 (da) Oral vaccine, som omfatter antigen knyttet til overfladen af røde blodlegemer
ATE277633T1 (de) Präparate und verfahren zum auslösen von ctl- immunität
AU7791887A (en) Use of nucleocapsid protein VP6 in vaccine compositions
ES2619332T3 (es) Fosfatasa alcalina dirigida al hueso, kits y métodos de uso de la misma
NZ503763A (en) Antigenic compositions and vaccines comprising a high molecular weight (HMW) protein of Clamydia for therapeutic and prophylactic use
IL85316A0 (en) Nona-and decapeptide analogs of lhrh,their preparation and pharmaceutical compositions containing them
NO180584C (no) Bisnaftalimider som inneholder aminosyreavledete linkere, for anvendelse som antikreftmidler, samt farmasöytiske preparater
ATE404583T1 (de) Funktionelle antagonisten von hedgehog-aktivität
BR9912176A (pt) Epìtopos de célula auxiliar t artificial como estimuladores imunes para imunógenos de peptìdeo sintéticos incluindo peptìdeos de lhrh imunogênicos
AU4622693A (en) Potentiation of immunogenic response
GB8912651D0 (en) Peptide fragments of hiv
FI964045A0 (fi) CCK:ta tai gastriinia säätelevä 5-heterosykli-1,5-bentsodiatsepiinejä
SE8604991L (sv) Tillvexthemmande peptid fran ormgift
RU94040393A (ru) Синтетические пептиды для вакцины против краснухи
ZA941853B (en) Stimulation of immune response by viral protein
ATE26109T1 (de) Acetylcystein-salze, ihre herstellung und verwendung.
BR9905780A (pt) Antìgenos vacinais de leptospira para prevenção da laptospirose
BR9911388A (pt) Imunógeno de somatostatina sintético para promoção de crescimento em animais de fazenda
ID27162A (id) Peptida antigen tumor yang dibatasi hla-a2 yang berasal dari sart-1