PT2204187E - Vacina contra a gripe humana contendo quatro péptidos de influenza - Google Patents
Vacina contra a gripe humana contendo quatro péptidos de influenza Download PDFInfo
- Publication number
- PT2204187E PT2204187E PT10003160T PT10003160T PT2204187E PT 2204187 E PT2204187 E PT 2204187E PT 10003160 T PT10003160 T PT 10003160T PT 10003160 T PT10003160 T PT 10003160T PT 2204187 E PT2204187 E PT 2204187E
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- Prior art keywords
- human
- influenza
- epitope
- epitopes
- mice
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
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- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
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- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12733198A IL127331A0 (en) | 1998-11-30 | 1998-11-30 | Peptide-based vaccine for influenza |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2204187E true PT2204187E (pt) | 2012-08-10 |
Family
ID=11072200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT10003160T PT2204187E (pt) | 1998-11-30 | 1999-11-28 | Vacina contra a gripe humana contendo quatro péptidos de influenza |
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| EP (2) | EP1135159A2 (enExample) |
| JP (1) | JP2002531415A (enExample) |
| KR (1) | KR100703571B1 (enExample) |
| AT (1) | ATE556719T1 (enExample) |
| AU (1) | AU766883B2 (enExample) |
| BR (1) | BR9915811A (enExample) |
| CA (1) | CA2352454C (enExample) |
| DK (1) | DK2204187T3 (enExample) |
| ES (1) | ES2389611T3 (enExample) |
| HK (1) | HK1040620A1 (enExample) |
| IL (3) | IL127331A0 (enExample) |
| NZ (1) | NZ511918A (enExample) |
| PT (1) | PT2204187E (enExample) |
| WO (1) | WO2000032228A2 (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL127331A0 (en) * | 1998-11-30 | 1999-09-22 | Yeda Res & Dev | Peptide-based vaccine for influenza |
| AU2002223398A1 (en) * | 2000-08-10 | 2002-04-08 | Tsinghua University | A vaccine for influenza virus and its preparation |
| FI20031536A0 (fi) * | 2003-10-20 | 2003-10-20 | Biotie Therapies Oyj | Korkean affiniteetin ligandit influenssavirukselle ja menetelmät niiden valmistamiseen |
| DK1692265T3 (da) | 2003-11-04 | 2011-11-21 | Univ Tulane | Fremgangsmåde til hindring af en virus-celle-fusion ved hæmning af fusionsinitieringsområdets funktion i RNA-vira med klasse 1-membranfusogene envelopeproteiner |
| GB0716992D0 (en) * | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
| WO2006074303A2 (en) * | 2005-01-05 | 2006-07-13 | Philadelphia Health And Education Corporation | Delivery vehicles, bioactive substances and viral vaccines |
| MY157941A (en) | 2005-01-19 | 2016-08-15 | Vaxinnate Corp | Compositions of pathogen-associated molecular patterns and methods of use |
| FI20060200A0 (fi) * | 2005-04-20 | 2006-02-27 | Glykos Finland Oy | Menetelmä ihmisen influenssaviruksen sialihahappositoumisspesifisyyden analysoimiseksi |
| MX2007015105A (es) * | 2005-06-01 | 2008-03-18 | Variation Biotechnologies Inc | Formulacion de vacuna de influenza a base de peptido. |
| US7871626B2 (en) * | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| US7468187B2 (en) * | 2005-10-18 | 2008-12-23 | Iowa State University Research Foundation, Inc. | Canine influenza virus and related compositions and methods of use |
| WO2007051036A2 (en) * | 2005-10-26 | 2007-05-03 | Protelix, Inc. | Influenza combinatorial antigen vaccine |
| US9533036B2 (en) * | 2005-11-07 | 2017-01-03 | Microvax, Llc | Methods for generating immune responses to influenza antigens with a secretable CD40L fusion protein |
| AU2006322907B2 (en) * | 2005-12-06 | 2012-08-02 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Improved influenza vaccine |
| HUE049580T2 (hu) * | 2006-01-27 | 2020-09-28 | Seqirus Uk Ltd | Hemagglutinint és mátrixfehérjéket tartalmazó, influenza elleni oltóanyagok |
| GB0613977D0 (en) | 2006-02-07 | 2006-08-23 | Peptcell Ltd | Peptide sequences and compositions |
| ES2534332T3 (es) * | 2006-03-07 | 2015-04-21 | Vaxinnate Corporation | Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas |
| US20080208486A1 (en) * | 2006-03-23 | 2008-08-28 | Jari Natunen | Integrated System, Device and Use Thereof |
| US8222204B2 (en) | 2006-05-03 | 2012-07-17 | The Administrators of the Tulane Educational Fund and Autoimmune Technologies, LLC | Influenza inhibiting compositions and methods |
| WO2008002663A2 (en) * | 2006-06-28 | 2008-01-03 | The Board Of Trustees Of The Leland Stanford Junior University | Immunogenic protein constructs |
| FI20060946A0 (fi) * | 2006-10-26 | 2006-10-26 | Glykos Finland Oy | Influenssaviruksen nukleiinihappoja ja peptidejä |
| EP2139908A4 (en) | 2007-03-12 | 2011-02-16 | Antigen Express Inc | REMOVAL OF PROTEIN Li INVOLVED IN Li-RNAi CONSTRUCTIONS IN ANTICANCER IMMUNOTHERAPY |
| JP5654345B2 (ja) | 2007-08-02 | 2015-01-14 | ビオンドヴァックス ファーマシューティカルズ リミテッド | 多量体マルチエピトープインフルエンザワクチン |
| CA2721246A1 (en) | 2008-04-18 | 2009-10-22 | Vaxinnate Corporation | Deletion mutants of flagellin and methods of use |
| CA2721800A1 (en) | 2008-04-21 | 2009-10-29 | Nanobio Corporation | Nanoemulsion influenza vaccine |
| JP2011519834A (ja) * | 2008-04-25 | 2011-07-14 | インスティチュート フォー システムズ バイオロジー | フラジェリンポリペプチドワクチン |
| WO2009135152A2 (en) | 2008-05-02 | 2009-11-05 | University Of Rochester | Arrayed detector system for measurement of influenza immune response |
| WO2010144797A2 (en) | 2009-06-12 | 2010-12-16 | Vaccine Technologies, Incorporated | Influenza vaccines with enhanced immunogenicity and uses thereof |
| WO2011005772A1 (en) | 2009-07-06 | 2011-01-13 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| ES2573427T3 (es) | 2009-07-06 | 2016-06-07 | Variation Biotechnologies Inc. | Procedimientos para preparar vesículas y formulaciones producidas a partir de las mismas |
| CA2840079C (en) | 2010-07-06 | 2018-07-03 | Variation Biotechnologies Inc. | Compositions and methods for treating influenza |
| WO2012097346A1 (en) | 2011-01-13 | 2012-07-19 | Variation Biotechnologies, Inc. | Compositions and methods for treating viral infections |
| CN107296792B (zh) | 2011-01-13 | 2021-07-27 | 变异生物技术公司 | 囊泡及由其产生之制剂的制备方法 |
| WO2012114323A1 (en) | 2011-02-22 | 2012-08-30 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
| CA2840982C (en) | 2011-07-06 | 2022-06-07 | Vira BITKO | Human respiratory syncytial virus vaccine |
| WO2013028738A1 (en) | 2011-08-22 | 2013-02-28 | Nanobio Corporation | Herpes simplex virus nanoemulsion vaccine |
| EP2780350B1 (en) | 2011-11-18 | 2019-03-06 | Variation Biotechnologies Inc. | Synthetic derivatives of mpl and uses thereof |
| CA2894442C (en) | 2012-01-12 | 2020-01-21 | Variation Biotechnologies Inc. | Compositions and methods for treating viral infections |
| US20150079077A1 (en) | 2012-01-27 | 2015-03-19 | Variation Biotechnologies, Inc. | Methods and compositions for therapeutic agents |
| US8932598B2 (en) | 2012-08-28 | 2015-01-13 | Vaxinnate Corporation | Fusion proteins and methods of use |
| KR20140099828A (ko) | 2013-02-05 | 2014-08-13 | 닛토덴코 가부시키가이샤 | 점막 투여용 백신 조성물 |
| EP2762152A1 (en) | 2013-02-05 | 2014-08-06 | Nitto Denko Corporation | WT1 peptide cancer vaccine composition for transdermal administration |
| CN103961306A (zh) | 2013-02-05 | 2014-08-06 | 日东电工株式会社 | 经皮给予用疫苗组合物 |
| EP3662927A3 (en) | 2013-02-05 | 2020-10-21 | Nitto Denko Corporation | Vaccine composition |
| RU2697443C2 (ru) | 2013-02-05 | 2019-08-14 | Нитто Денко Корпорейшн | Препарат противораковой вакцины, содержащий пептид wt1, в форме ленты трансдермального введения |
| US10206985B2 (en) | 2013-02-05 | 2019-02-19 | Nitto Denko Corporation | WT1 peptide cancer vaccine composition for mucosal administration |
| RU2014102948A (ru) * | 2013-02-05 | 2015-08-10 | Нитто Денко Корпорейшн | Вакцинная композиция для мукозального введения |
| CN103961698A (zh) | 2013-02-05 | 2014-08-06 | 日东电工株式会社 | 经皮或粘膜给予用疫苗组合物 |
| CA2841016A1 (en) | 2013-02-05 | 2014-08-05 | Nitto Denko Corporation | Wt1 peptide cancer vaccine composition for transdermal administration |
| US20140220100A1 (en) | 2013-02-05 | 2014-08-07 | Nitto Denko Corporation | Vaccine composition for transdermal administration |
| RU2531235C2 (ru) | 2013-02-15 | 2014-10-20 | Общество с ограниченной ответственностью "Универсальные БиоСистемы" (ООО "УБС") | Поливалентная вакцина против гриппа на основе гибридного белка |
| CN103901202B (zh) * | 2014-04-04 | 2015-08-12 | 中国人民解放军成都军区疾病预防控制中心 | 基于共有表位甲型流感病毒抗体通用型竞争性elisa检测方法 |
| US10925936B2 (en) | 2014-09-03 | 2021-02-23 | Nitto Denko Corporation | Vaccine pharmaceutical composition for cell-mediated immunity containing bisphosphonates |
| EP3189852B1 (en) | 2014-09-03 | 2021-04-07 | Nitto Denko Corporation | Bisphosphonate-containing pharmaceutical vaccine composition for humoral immunity |
| US11278616B2 (en) | 2015-08-06 | 2022-03-22 | Nitto Denko Corporation | Immunity induction promoting composition, and vaccine pharmaceutical composition |
| WO2018126060A1 (en) * | 2016-12-28 | 2018-07-05 | Invvax, Inc. | Influenza vaccines |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| IL101639A0 (en) | 1992-04-17 | 1992-12-30 | Yeda Res & Dev | Recombinant influenza vaccines |
| AU3036597A (en) * | 1996-05-21 | 1997-12-09 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for using peptide complexes/major histocompatibility complex to obtain or purify antigen-specific t cells and to stimulate t cells |
| IL127331A0 (en) * | 1998-11-30 | 1999-09-22 | Yeda Res & Dev | Peptide-based vaccine for influenza |
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1998
- 1998-11-30 IL IL12733198A patent/IL127331A0/xx unknown
-
1999
- 1999-11-28 DK DK10003160.8T patent/DK2204187T3/da active
- 1999-11-28 AT AT10003160T patent/ATE556719T1/de active
- 1999-11-28 BR BR9915811-6A patent/BR9915811A/pt not_active IP Right Cessation
- 1999-11-28 PT PT10003160T patent/PT2204187E/pt unknown
- 1999-11-28 ES ES10003160T patent/ES2389611T3/es not_active Expired - Lifetime
- 1999-11-28 US US09/856,920 patent/US6740325B1/en not_active Expired - Lifetime
- 1999-11-28 CA CA2352454A patent/CA2352454C/en not_active Expired - Lifetime
- 1999-11-28 AU AU14066/00A patent/AU766883B2/en not_active Expired
- 1999-11-28 KR KR1020017006639A patent/KR100703571B1/ko not_active Expired - Lifetime
- 1999-11-28 IL IL14336799A patent/IL143367A0/xx active IP Right Grant
- 1999-11-28 EP EP99972929A patent/EP1135159A2/en not_active Withdrawn
- 1999-11-28 EP EP10003160A patent/EP2204187B1/en not_active Expired - Lifetime
- 1999-11-28 JP JP2000584919A patent/JP2002531415A/ja active Pending
- 1999-11-28 HK HK02102105.6A patent/HK1040620A1/zh unknown
- 1999-11-28 WO PCT/IL1999/000640 patent/WO2000032228A2/en not_active Ceased
- 1999-11-28 NZ NZ511918A patent/NZ511918A/en not_active IP Right Cessation
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2001
- 2001-05-24 IL IL143367A patent/IL143367A/en not_active IP Right Cessation
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2004
- 2004-05-17 US US10/846,548 patent/US7192595B2/en not_active Expired - Lifetime
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2007
- 2007-02-07 US US11/672,429 patent/US7514086B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1135159A2 (en) | 2001-09-26 |
| KR100703571B1 (ko) | 2007-04-05 |
| EP2204187A1 (en) | 2010-07-07 |
| IL143367A0 (en) | 2002-04-21 |
| US6740325B1 (en) | 2004-05-25 |
| US20050002954A1 (en) | 2005-01-06 |
| CA2352454A1 (en) | 2000-06-08 |
| HK1040620A1 (zh) | 2002-06-21 |
| WO2000032228A3 (en) | 2000-10-05 |
| DK2204187T3 (da) | 2012-08-20 |
| JP2002531415A (ja) | 2002-09-24 |
| CA2352454C (en) | 2013-02-05 |
| IL127331A0 (en) | 1999-09-22 |
| US7192595B2 (en) | 2007-03-20 |
| BR9915811A (pt) | 2001-08-21 |
| US20070122424A1 (en) | 2007-05-31 |
| NZ511918A (en) | 2003-08-29 |
| AU766883B2 (en) | 2003-10-23 |
| EP2204187B1 (en) | 2012-05-09 |
| AU1406600A (en) | 2000-06-19 |
| IL143367A (en) | 2006-09-05 |
| US7514086B2 (en) | 2009-04-07 |
| HK1145448A1 (en) | 2011-04-21 |
| ES2389611T3 (es) | 2012-10-29 |
| KR20010089512A (ko) | 2001-10-06 |
| ATE556719T1 (de) | 2012-05-15 |
| WO2000032228A2 (en) | 2000-06-08 |
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