IL127214A0 - Inhibition of serotonin reuptake - Google Patents

Inhibition of serotonin reuptake

Info

Publication number
IL127214A0
IL127214A0 IL12721497A IL12721497A IL127214A0 IL 127214 A0 IL127214 A0 IL 127214A0 IL 12721497 A IL12721497 A IL 12721497A IL 12721497 A IL12721497 A IL 12721497A IL 127214 A0 IL127214 A0 IL 127214A0
Authority
IL
Israel
Prior art keywords
inhibition
serotonin reuptake
reuptake
serotonin
Prior art date
Application number
IL12721497A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL127214A0 publication Critical patent/IL127214A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
IL12721497A 1996-06-14 1997-06-12 Inhibition of serotonin reuptake IL127214A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1975196P 1996-06-14 1996-06-14
PCT/US1997/010243 WO1997047302A1 (en) 1996-06-14 1997-06-12 Inhibition of serotonin reuptake

Publications (1)

Publication Number Publication Date
IL127214A0 true IL127214A0 (en) 1999-09-22

Family

ID=21794846

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12721497A IL127214A0 (en) 1996-06-14 1997-06-12 Inhibition of serotonin reuptake

Country Status (9)

Country Link
US (2) US5846982A (xx)
EP (1) EP0812826A1 (xx)
JP (1) JP2000512296A (xx)
KR (1) KR20000016624A (xx)
AU (1) AU3390797A (xx)
BR (1) BR9709726A (xx)
CA (1) CA2256649A1 (xx)
IL (1) IL127214A0 (xx)
WO (1) WO1997047302A1 (xx)

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US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
EP1068199B1 (en) * 1998-04-08 2002-11-13 Wyeth N-aryloxyethyl-indoly-alkylamines for the treatment of depression
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
CA2330577A1 (en) * 1998-04-29 1999-11-04 American Home Products Corporation Serotonergic agents
US6303627B1 (en) 1998-06-19 2001-10-16 Eli Lilly And Company Inhibitors of serotonin reuptake
US6225324B1 (en) * 1999-01-28 2001-05-01 Bristol-Myers Squibb Company Antidepressant heterocyclic compounds
JP4597386B2 (ja) * 1999-04-21 2010-12-15 エヌピーエス ファーマシューティカルス，インコーポレーテッド ５−ｈｔ６親和性を有するピペリジン−インドール化合物
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
AU779832B2 (en) * 1999-08-12 2005-02-10 Nps Pharmaceuticals, Inc. Azaindoles having serotonin receptor affinity
US6686374B1 (en) 1999-08-12 2004-02-03 Nps Allelix Corp. Azaindoles having serotonin receptor affinity
NZ517038A (en) 1999-09-03 2003-04-29 Lilly Co Eli Use of serotonin reuptake inihibitor in medicaments for treating sexual dysfunction
CN1149212C (zh) * 1999-09-29 2004-05-12 伊莱利利公司 用作再摄入抑制剂的哌啶衍生物
MXPA02001993A (es) 1999-09-29 2002-09-18 Lilly Co Eli Derivados de piperidina como inhibidores de la reabsorcion de serotonina.
AU2251801A (en) * 1999-12-20 2001-07-03 Eli Lilly And Company Piperidine derivatives and their use as serotonin receptor antagonists
WO2001046147A1 (en) * 1999-12-20 2001-06-28 Eli Lilly And Company A process for preparing 4-substituted piperidines
CA2409821A1 (en) * 2000-05-18 2002-11-18 Yoshikazu Ikeda Novel benzothiophene derivatives
WO2002032863A1 (en) 2000-10-20 2002-04-25 Biovitrum Ab 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
US20040198809A1 (en) * 2001-05-01 2004-10-07 Connie Sanchez Use of enantiomeric pure escitalopram
EP2036547A3 (en) * 2001-07-20 2009-12-23 Psychogenics Inc. Treatment for Attention-Deficit Hyperactivity Disorder
DK1539742T3 (da) * 2002-06-24 2006-12-27 Schering Corp Indolderivater, der er nyttige som histamin H3-antagonister
US7282507B2 (en) * 2004-05-03 2007-10-16 Janssen Pharmaceutica N.V. Indole derivatives as selective androgen receptor modulators (SARMS)
AR050253A1 (es) 2004-06-24 2006-10-11 Smithkline Beecham Corp Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento
PE20060748A1 (es) 2004-09-21 2006-10-01 Smithkline Beecham Corp Derivados de indolcarboxamida como inhibidores de quinasa ikk2
KR100678277B1 (ko) * 2004-11-30 2007-02-02 삼성전자주식회사 멀티미디어 데이터 송수신 시스템에서 지연 시간에 대한측정값을 제공하는 지연 시간 측정 장치와 그 방법
EA013123B1 (ru) 2005-04-13 2010-02-26 Ньюрэксон, Инк. Замещенные индолы, обладающие активностью ингибирования nos
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
EP1873144B1 (en) * 2005-04-20 2014-07-23 Takeda Pharmaceutical Company Limited Fused heterocyclic compound
ATE531706T1 (de) * 2005-04-30 2011-11-15 Boehringer Ingelheim Int Neue piperidin-substituierte indole und ihre verwendung als ccr-3-modulatoren
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
WO2007098418A1 (en) 2006-02-17 2007-08-30 Memory Pharmaceuticals Corporation Compounds having 5-ht6 receptor affinity
AU2007240078B2 (en) 2006-04-13 2013-07-25 Neuraxon, Inc. 1,5 and 3,6- substituted indole compounds having NOS inhibitory activity
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
WO2009049030A1 (en) * 2007-10-09 2009-04-16 Triton Biopharma, Llc Method to use compositions having antidepressant anxiolytic and other neurological activity and compositions of matter
SG185991A1 (en) 2007-11-16 2012-12-28 Neuraxon Inc Indole compounds and methods for treating visceral pain
WO2010102968A1 (en) 2009-03-10 2010-09-16 Glaxo Group Limited Indole derivatives as ikk2 inhibitors
TWI429652B (zh) 2011-08-05 2014-03-11 Ind Tech Res Inst 有機金屬化合物及包含其之有機電激發光裝置
IL303467A (en) * 2020-12-07 2023-08-01 Mindset Pharma Inc 3-cyclic amine-indole derivatives as serotonergics for the treatment of central nervous system disorders
WO2023144764A1 (en) 2022-01-29 2023-08-03 Suven Life Sciences Limited Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders

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DK574274A (xx) * 1973-12-06 1975-07-28 Ciba Geigy Ag
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
FR2426465B1 (xx) * 1978-01-16 1983-04-29 Roussel Uclaf
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
FR2486081A2 (fr) * 1979-06-12 1982-01-08 Roussel Uclaf Le (-) 4-(3-piperidinyl) 1h-indole et ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant
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SE8004129L (sv) * 1979-07-13 1981-01-14 Roussel Uclaf Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
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JPH06234633A (ja) * 1993-02-10 1994-08-23 Ajinomoto Co Inc アミン誘導体およびこれを含有する抗血小板剤
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Also Published As

Publication number Publication date
BR9709726A (pt) 1999-08-10
EP0812826A1 (en) 1997-12-17
KR20000016624A (ko) 2000-03-25
JP2000512296A (ja) 2000-09-19
US5846982A (en) 1998-12-08
CA2256649A1 (en) 1997-12-18
WO1997047302A1 (en) 1997-12-18
AU3390797A (en) 1998-01-07
US6046215A (en) 2000-04-04

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