IL126347A - Enhancement of nmr and mri in the presence of hyperpolarized noble gases - Google Patents

Enhancement of nmr and mri in the presence of hyperpolarized noble gases

Info

Publication number
IL126347A
IL126347A IL12634797A IL12634797A IL126347A IL 126347 A IL126347 A IL 126347A IL 12634797 A IL12634797 A IL 12634797A IL 12634797 A IL12634797 A IL 12634797A IL 126347 A IL126347 A IL 126347A
Authority
IL
Israel
Prior art keywords
mri
nmr
enhancement
noble gases
hyperpolarized noble
Prior art date
Application number
IL12634797A
Other languages
English (en)
Other versions
IL126347A0 (en
Original Assignee
Lawrence Berkeley National Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lawrence Berkeley National Lab filed Critical Lawrence Berkeley National Lab
Publication of IL126347A0 publication Critical patent/IL126347A0/xx
Priority to IL14649001A priority Critical patent/IL146490A0/xx
Priority to IL14648901A priority patent/IL146489A0/xx
Priority to IL14648801A priority patent/IL146488A0/xx
Publication of IL126347A publication Critical patent/IL126347A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12634797A 1996-03-29 1997-03-28 Enhancement of nmr and mri in the presence of hyperpolarized noble gases IL126347A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL14649001A IL146490A0 (en) 1996-03-29 2001-11-14 Enhancement of nmr and mri in the presence of hyperpolarized noble gases
IL14648901A IL146489A0 (en) 1996-03-29 2001-11-14 Enhancement of nmr and mri in the presence of hyperpolarized noble gases
IL14648801A IL146488A0 (en) 1996-03-29 2001-11-14 Enhancement of nmr and mri in the presence of hyperpolarized noble gases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1432196P 1996-03-29 1996-03-29
PCT/US1997/005166 WO1997037239A1 (en) 1996-03-29 1997-03-28 Enhancement of nmr and mri in the presence of hyperpolarized noble gases

Publications (2)

Publication Number Publication Date
IL126347A0 IL126347A0 (en) 1999-05-09
IL126347A true IL126347A (en) 2003-11-23

Family

ID=21764774

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12634797A IL126347A (en) 1996-03-29 1997-03-28 Enhancement of nmr and mri in the presence of hyperpolarized noble gases

Country Status (11)

Country Link
US (3) US6426058B1 (pt)
EP (1) EP0890114A1 (pt)
JP (1) JP2001503646A (pt)
AU (1) AU2426697A (pt)
BR (1) BR9711082A (pt)
CA (1) CA2250401A1 (pt)
FI (1) FI982069A (pt)
IL (1) IL126347A (pt)
NO (1) NO984510L (pt)
RU (1) RU2186405C2 (pt)
WO (1) WO1997037239A1 (pt)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
IL126347A (en) 1996-03-29 2003-11-23 Lawrence Berkeley National Lab Enhancement of nmr and mri in the presence of hyperpolarized noble gases
US5809801A (en) * 1996-03-29 1998-09-22 The Trustees Of Princeton University Cryogenic accumulator for spin-polarized xenon-129
US8765099B2 (en) * 1996-04-08 2014-07-01 Koninklijke Philips N.V. Magnetic resonance imaging hyperpolarization of liquids or solids by light with orbital angular momentum
AU726115C (en) * 1997-08-12 2001-12-20 Bracco Research S.A. Administrable compositions and methods for magnetic resonance imaging
IL136116A0 (en) 1997-11-14 2001-05-20 Weiler Norbert Apparatus for fluid administration
DE69829231T2 (de) 1997-12-12 2006-04-06 Medi-Physics, Inc. Verfahren zum Sammeln und Auftauen polarisierter Gase, dessen Sammler und Heizmanschette
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
WO1999066255A2 (en) * 1998-06-17 1999-12-23 Medi-Physics, Inc. Resilient containers for hyperpolarized gases
US6423387B1 (en) 1998-06-17 2002-07-23 Medi-Physics, Inc. Resilient containers for hyperpolarized gases and associated methods
US6128918A (en) * 1998-07-30 2000-10-10 Medi-Physics, Inc. Containers for hyperpolarized gases and associated methods
AU747311B2 (en) 1998-06-17 2002-05-16 Medi-Physics, Inc. Hyperpolarized gas transport device and associated transport method
US6523356B2 (en) 1998-09-30 2003-02-25 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6286319B1 (en) 1998-09-30 2001-09-11 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6237363B1 (en) 1998-09-30 2001-05-29 Medi-Physics, Inc. Hyperpolarized noble gas extraction methods masking methods and associated transport containers
US6284222B1 (en) 1998-11-03 2001-09-04 Medi--Physics, Inc. Hyperpolarized helium-3 microbubble gas entrapment methods
GB9828853D0 (en) * 1998-12-30 1999-02-17 Nycomed Amersham Plc Nmr spectroscopy method
JP2002534687A (ja) * 1998-12-30 2002-10-15 アメルシャム・パブリック・リミテッド・カンパニー 過分極を使用したｎｍｒ分光学アッセイ
AU4686899A (en) 1999-02-23 2000-09-14 Medi-Physics, Inc. Portable system for monitoring the polarization level of a hyperpolarized gas during transport
US6295834B1 (en) 1999-06-30 2001-10-02 Medi-Physics, Inc. NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production
US6648130B1 (en) 1999-08-11 2003-11-18 Medi-Physics, Inc. Hyperpolarized gas transport and storage devices and associated transport and storage methods using permanent magnets
DE10000675C2 (de) 2000-01-11 2001-11-15 Otten Ernst Wilhelm Lineardurchführung, Vorrichtung und Verfahren zur hochproduktiven Erzeugung von hoch kernspinpolarisiertem Helium-3 Gas
JP2003526437A (ja) 2000-03-13 2003-09-09 メディ−フィジックス・インコーポレイテッド ガス状過分極１２９Ｘｅの直接注射を使用する診断処置並びに関連するシステムおよび生成物
US6845262B2 (en) * 2000-03-29 2005-01-18 The Brigham And Women's Hospital, Inc. Low-field MRI
US6775568B2 (en) * 2000-04-12 2004-08-10 University Of Virginia Patent Foundation Exchange-based NMR imaging and spectroscopy of hyperpolarized xenon-129
GB0014463D0 (en) * 2000-06-14 2000-08-09 Nycomed Amersham Plc NMR Method
US20030165431A1 (en) * 2000-07-13 2003-09-04 The Regents Of The University Of California Method for detecting macromolecular conformational change and binding information
US7061237B2 (en) * 2000-07-13 2006-06-13 The Regents Of The University Of California Remote NMR/MRI detection of laser polarized gases
US6652833B2 (en) * 2000-07-13 2003-11-25 The Regents Of The University Of California Functionalized active-nucleus complex sensor
CA2414610A1 (en) 2000-07-13 2002-01-24 Medi-Physics, Inc. Diagnostic procedures using 129xe spectroscopy characteristic chemical shift to detect pathology in vivo
GB0022341D0 (en) * 2000-09-12 2000-10-25 Nycomed Imaging As Method
EP2204662A1 (en) * 2000-11-03 2010-07-07 GE Healthcare AS Device for hyperpolarising and dissolving solid material for NMR analyses
US6915151B2 (en) * 2001-02-08 2005-07-05 Trustees Of The University Of Pennsylvania Quantitative pulmonary imaging
FR2823967B1 (fr) * 2001-04-25 2003-08-01 Univ Claude Bernard Lyon Procede et installation pour la production d'images en resonance magnetique
US6519489B2 (en) * 2001-04-27 2003-02-11 Siemens Aktiengesellschaft Clinical method for measuring cerebrospinal fluid perfusion by magnetic resonance tomography
US7126332B2 (en) * 2001-07-20 2006-10-24 Baker Hughes Incorporated Downhole high resolution NMR spectroscopy with polarization enhancement
US7179450B2 (en) 2001-09-20 2007-02-20 Medi-Physics, Inc. Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
US7287390B2 (en) * 2001-10-22 2007-10-30 Medi-Physics, Inc. Optical pumping modules, polarized gas blending and dispensing systems, and automated polarized gas distribution systems and related devices and methods
JP2005515406A (ja) * 2001-10-31 2005-05-26 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア レーザーで分極化されたガスの遠隔ｎｍｒ／ｍｒｉ検出
AP2004003127A0 (en) 2002-02-06 2004-09-30 Univ California Squid detected NMR and MR1 at ultralow fields
NO20023357D0 (no) * 2002-04-19 2002-07-11 Amersham Health As Blanding
US7830881B2 (en) * 2002-07-16 2010-11-09 Panasonic Corporation Content receiver and content transmitter
NO20025124D0 (no) * 2002-10-25 2002-10-25 Amersham Health As Metode
NO20025738D0 (no) * 2002-11-29 2002-11-29 Amersham Health As Metode
DE10259793B4 (de) * 2002-12-19 2009-10-15 Siemens Ag Verfahren zur Bildgebung eines Stoffwechselvorgangs eines Lebewesens
JP3998243B2 (ja) * 2003-01-10 2007-10-24 東横化学株式会社 核スピン偏極キセノンガスの製造方法及び製造装置
US6937020B2 (en) * 2003-02-04 2005-08-30 The University Of Kansas Solid-state nuclear magnetic resonance probe
KR20060008321A (ko) * 2003-05-16 2006-01-26 더 비오씨 그룹 인코포레이티드 샘플 질량을 결정하기 위한 자기공명 방법
US7199581B2 (en) * 2003-05-16 2007-04-03 The Boc Group, Inc. Magnetic resonance measuring system determining the mass of samples in a production line with monitored drift compensation
JP2007502431A (ja) * 2003-05-16 2007-02-08 ザ・ビーオーシー・グループ・インコーポレーテッド 磁気共鳴方法
CN1787885A (zh) 2003-05-16 2006-06-14 波克股份有限公司 Nmr称重核查系统的清洁方法
DE10324353A1 (de) * 2003-05-27 2005-01-13 Forschungszentrum Jülich GmbH Verfahren zum Transport eines hyperpolarisierten Edelgases
NO20035626D0 (no) * 2003-12-17 2003-12-17 Amersham Health As Metode
DE102004002639A1 (de) * 2004-01-19 2005-09-15 Forschungszentrum Jülich GmbH Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens
WO2005086931A2 (en) * 2004-03-10 2005-09-22 University Of Virginia Patent Foundation System and method for improved detection and assessment of changes in lung-tissue structure
WO2005086932A2 (en) * 2004-03-10 2005-09-22 University Of Virginia Patent Foundation Exchange-weighted xenon-129 nuclear magnetic resonance system and related method
US7084627B2 (en) * 2004-04-30 2006-08-01 The Boc Group, Inc. Method for triggering NMR measurement in a NMR check weighing system
US7061239B2 (en) * 2004-04-30 2006-06-13 The Boc Group, Inc. Method for magnetic field tracking in a NMR check weighing system
US7064548B2 (en) * 2004-04-30 2006-06-20 The Boc Group, Inc. RF probe apparatus for NMR check weighing system
US7002346B2 (en) * 2004-05-03 2006-02-21 The Boc Group, Inc. Method for accurate determination of sample temperature in a NMR check weighing system
JP2007536509A (ja) * 2004-05-04 2007-12-13 ザ・ビーオーシー・グループ・インコーポレーテッド Ｎｍｒ重量測定検査システムにおける近接する試料の影響の補償方法。
DE102004032080A1 (de) * 2004-07-02 2006-01-26 Forschungszentrum Jülich GmbH Verfahren und Vorrichtung für hochauflösende NMR-Spektroskopie
US7750633B2 (en) * 2004-07-22 2010-07-06 The Regents Of The University Of California Low field magnetic resonance imaging
FI20045381A0 (fi) * 2004-10-12 2004-10-12 Oulun Yliopisto Huokosominaisuuden määritysmenetelmä, näyteyksikön valmistusmenetelmä ja näyteyksikkö
WO2006104096A1 (ja) * 2005-03-28 2006-10-05 High Energy Accelerator Research Organization 希ガス封入用容器及び当該容器を用いた希ガス原子核の偏極方法
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
DE102005017927A1 (de) * 2005-04-18 2006-10-26 Forschungszentrum Jülich GmbH Hyperpolarisation von Li und weiteren Kernen
US7787930B2 (en) * 2005-04-25 2010-08-31 The United States Of America As Represented By The Department Of Health And Human Services Adiabatic T2 preparation sequence for magnetic resonance imaging with reduced B1 sensitivity
DE102005026604A1 (de) * 2005-06-09 2006-12-14 Membrana Gmbh Verfahren zum Lösen von Gasen mit kurzlebigen physikalischen Eigenschaften in einer Flüssigkeit
US8614575B2 (en) * 2005-06-17 2013-12-24 The Regents Of The University Of California NMR, MRI, and spectroscopic MRI in inhomogeneous fields
JP2007021008A (ja) * 2005-07-20 2007-02-01 Hitachi Ltd Ｄｎｐ過分極手段を備えた磁気共鳴イメージング装置
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
EP1940475A4 (en) * 2005-09-28 2010-05-26 Harvard College HYPERPOLARIZED SOLID MATERIALS WITH LONG SPIN RECOVERY TIMES FOR USE AS IMAGING MEANS IN MAGNETIC RESONANCE TOMOGRAPHY
AU2006326596A1 (en) * 2005-12-10 2007-06-21 The President And Fellows Of Harvard College In situ hyperpolarization of imaging agents
JP2009523172A (ja) * 2006-01-11 2009-06-18 プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ 造影剤のエクスビボ過分極
US8703102B2 (en) * 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
EP1986702A4 (en) * 2006-02-21 2012-12-12 Avrum Belzer METHODS, SYSTEMS AND COMPOSITIONS FOR HYPERPORALIZATION
US9207298B2 (en) 2011-03-23 2015-12-08 Millikelvin Technologies Llc Techniques, systems and machine readable programs for magnetic resonance
US7576538B2 (en) * 2006-03-14 2009-08-18 Thomas Meersmann Nuclear electric quadrupolar properties of hyperpolarized gases to probe surfaces and interfaces
WO2007143401A2 (en) * 2006-06-02 2007-12-13 Koninklijke Philips Electronics, N.V. Multi-modal imaging system and workstation with support for structured hypothesis testing
WO2008027162A2 (en) * 2006-08-28 2008-03-06 The Trustees Of The University Of Pennsylvania 129xe biosensors and their use
CN101553168A (zh) 2006-10-03 2009-10-07 杜克大学 用于使用超极化129xe mri估计肺部的气体传递的系统和方法
US8633693B2 (en) * 2007-04-02 2014-01-21 The Regents Of The University Of California Rotating-frame gradient fields for magnetic resonance imaging and nuclear magnetic resonance in low fields
US7741844B2 (en) * 2007-05-07 2010-06-22 General Electric Company Method and system for magnetic resonance imaging using labeled contrast agents
US20100322864A1 (en) * 2008-01-10 2010-12-23 President And Fellows Of Harvard College Telemetry through remote detection of nmr-active particles
WO2009143368A2 (en) * 2008-05-23 2009-11-26 University Of Utah Non-cryogenic storage cell for hyperpolarized 129xe
US8222022B2 (en) * 2008-07-07 2012-07-17 The Trustees Of The University Of Pennsylvania Tri-functionalized cryptophane biosensors
US9289518B2 (en) * 2008-08-22 2016-03-22 The Brigham And Women's Hospital Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE
US20100092390A1 (en) * 2008-10-09 2010-04-15 President And Fellows Of Harvard College Methods for Making Particles Having Long Spin-Lattice Relaxation Times
CN102238923B (zh) * 2008-12-05 2014-03-05 皇家飞利浦电子股份有限公司 使用具有轨道角动量的光诱发超极化mri的有源装置追踪
US9297866B2 (en) * 2008-12-31 2016-03-29 Koninklijke Philips N.V. General inductive handpiece for active devices
EP2443443A1 (en) * 2009-06-19 2012-04-25 Koninklijke Philips Electronics N.V. Mri with hyperpolarisation device using photons with orbital angular momentum
BRPI1009657A2 (pt) * 2009-06-19 2016-03-15 Koninkl Philips Electronics Nv sistema de exame de resonância magnética, e, conjunto de terapia
CN102473297B (zh) * 2009-06-30 2015-07-15 皇家飞利浦电子股份有限公司 量化灌注分析
IN2012DN02418A (pt) 2009-08-31 2015-08-21 Millikelvin Technologies Llc
US20110068793A1 (en) * 2009-09-21 2011-03-24 The Regents Of The University Of California SOLVATED HYPERPOLARIZED XeNMR AND MRI SIGNAL AMPLIFICATION BY GAS EXTRACTION
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
US8892184B2 (en) 2010-10-18 2014-11-18 Siemens Medical Solutions Usa, Inc. Systems and methods for reducing interference in a dual modality imaging system
US9714995B2 (en) 2011-03-23 2017-07-25 Millikelvin Technologies Llc Techniques, systems and machine readable programs for magnetic resonance
FR2988857B1 (fr) * 2012-03-30 2015-02-20 Commissariat Energie Atomique Procede de determination de la resistance cellulaire aux medicaments.
WO2013186648A2 (en) * 2012-06-11 2013-12-19 Koninklijke Philips N.V. Fluid hyperpolarizer.
US20140037062A1 (en) * 2012-08-01 2014-02-06 Koninklijke Philips Electronics N.V. Image guided radiation therapy
US9329246B2 (en) * 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
US20140285192A1 (en) * 2013-03-15 2014-09-25 Millikelvin Technologies Llc Techniques, systems and machine readable programs for magnetic resonance
US9551768B2 (en) 2013-03-15 2017-01-24 East Carolina University NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease
EP2968126B1 (en) 2013-03-15 2022-04-06 The Board of Regents of The University of Texas System Liquids rich in noble gas and methods of their preparation and use
US10408895B2 (en) * 2013-03-15 2019-09-10 Bruker Biospin Corporation Polarization sample geometry
US10197643B2 (en) 2013-05-03 2019-02-05 Quantum Valley Investment Fund LP Transferring spin polarization
US10197642B2 (en) 2013-05-03 2019-02-05 Quantum Valley Investment Fund LP Using a thermally-isolated cavity to polarize a spin ensemble
KR101903300B1 (ko) 2014-07-22 2018-10-01 어드밴스드 테크놀러지 머티리얼즈, 인코포레이티드 연성 재료를 갖는 성형 플루오로중합체 브레이크 실
US10126438B2 (en) 2014-09-19 2018-11-13 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
EP3258850B1 (en) * 2015-02-20 2020-06-24 Bayer HealthCare LLC Contrast imaging agent with dissolved gas-evolving fluid
US10602957B2 (en) * 2015-06-30 2020-03-31 Varuna Biomedical Corporation Systems and methods for detecting and visualizing biofields with nuclear magnetic resonance imaging and QED quantum coherent fluid immersion
US11229712B2 (en) * 2016-06-03 2022-01-25 Lakehead University In vivo detection of a xenon-binding cage molecule
EP3513222A4 (en) 2016-09-15 2020-05-20 Yuan Zheng POLARIZED NUCLEAR IMAGING AND SPECTROSCOPY SYSTEMS AND METHODS
RU173112U1 (ru) * 2016-12-29 2017-08-14 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" (ТГУ, НИ ТГУ) Компактное устройство для газонасыщения массажного масла ксеноном
US11016152B2 (en) 2017-05-12 2021-05-25 Vanderbilt University Method for creating hyperpolarization at microtesla magnetic fields
US10481222B2 (en) * 2017-07-24 2019-11-19 General Electric Company Fluid path insert for a cryogenic cooling system
WO2019033139A1 (en) * 2017-08-17 2019-02-21 The University Of Melbourne MANUFACTURE OF HYPERPOLARIZED AGENTS
RU2665588C1 (ru) * 2017-11-23 2018-08-31 Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный университет" (СПбГУ) Лазерный спектрометр магнитного резонанса
FR3074302B1 (fr) * 2017-11-28 2019-11-22 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procede et appareil d'hyperpolarisation de spins, notamment electroniques
US10677874B2 (en) * 2018-02-20 2020-06-09 Wisconsin Alumni Research Foundation System and method for control of hyperpolarized gas-phase contamination in spectroscopic magnetic resonance imaging
US10775458B2 (en) 2018-03-05 2020-09-15 Texas Tech University System Method and system for non-invasive measurement of metabolic health
WO2020175695A1 (ja) * 2019-02-28 2020-09-03 国立大学法人九州大学 組成物および複合体
CN112268920B (zh) * 2020-10-13 2021-12-31 大连理工大学 应用mri原位测量储层温压下co2-盐水对流混合的装置及方法
WO2022115339A1 (en) * 2020-11-24 2022-06-02 The Johns Hopkins University Magnetic resonance imaging of glycogen and other polysaccharides by magnetic coupling with water
CN114487959B (zh) * 2022-01-26 2024-05-31 中国科学院精密测量科学与技术创新研究院 一种超低场核磁共振测量装置与方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4586511A (en) * 1983-03-04 1986-05-06 Children's Hospital Medical Center Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5773024A (en) 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
GB9203037D0 (en) 1992-02-11 1992-03-25 Salutar Inc Contrast agents
US5357959A (en) 1993-04-16 1994-10-25 Praxair Technology, Inc. Altered dipole moment magnetic resonance imaging method
US5545396A (en) 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
US5891643A (en) 1995-11-14 1999-04-06 Abbott Laboratories Use of nuclear magnetic resonance to design ligands to target biomolecules
US5698401A (en) 1995-11-14 1997-12-16 Abbott Laboratories Use of nuclear magnetic resonance to identify ligands to target biomolecules
US5665777A (en) 1995-11-14 1997-09-09 Abbott Laboratories Biphenyl hydroxamate inhibitors of matrix metalloproteinases
US5989827A (en) 1995-11-14 1999-11-23 Abbott Laboratories Use of nuclear magnetic resonance to design ligands to target biomolecules
US5642625A (en) 1996-03-29 1997-07-01 The Trustees Of Princeton University High volume hyperpolarizer for spin-polarized noble gas
US5809801A (en) * 1996-03-29 1998-09-22 The Trustees Of Princeton University Cryogenic accumulator for spin-polarized xenon-129
IL126347A (en) 1996-03-29 2003-11-23 Lawrence Berkeley National Lab Enhancement of nmr and mri in the presence of hyperpolarized noble gases
ES2189974T3 (es) 1996-09-11 2003-07-16 Imarx Pharmaceutical Corp Procedimientos mejorados para la obtencion de imagenes de diagnostico usando un agente de contraste y un vasodilatador.
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
KR20000052830A (ko) 1996-10-28 2000-08-25 조오지 디빈센조, 토브 아스 헬지, 에바 요한손 진단/치료제 또는 그와 관련된 개선
WO1998030918A1 (en) * 1997-01-08 1998-07-16 Nycomed Imaging As Method of magnetic resonance imaging
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6043024A (en) 1997-04-18 2000-03-28 Abbott Laboratories Use of one-dimensional nuclear magnetic resonance to identify ligands to target biomolecules
AU726115C (en) 1997-08-12 2001-12-20 Bracco Research S.A. Administrable compositions and methods for magnetic resonance imaging
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
AU3386799A (en) 1998-04-13 1999-11-01 Duke University (in vivo) magnetic resonance vascular imaging using laser-polarized gas microbubbles
US6023162A (en) 1998-07-23 2000-02-08 Duke University Three-dimensional morphology by magnetic resonance imaging
US6284222B1 (en) 1998-11-03 2001-09-04 Medi--Physics, Inc. Hyperpolarized helium-3 microbubble gas entrapment methods
US6288261B1 (en) 1998-12-18 2001-09-11 Abbott Laboratories Inhibitors of matrix metalloproteinases
DE19910102B4 (de) 1999-03-08 2006-06-01 Fischer, Markus, Dr.rer.nat. Proteinkonjugate, Verfahren, Vektoren, Proteine und DNA zu deren Herstellung, deren Verwendung, sowie Arzneimittel und Impfstoffe mit einem Gehalt derselben

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US7385395B2 (en) 2008-06-10
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US20050030026A1 (en) 2005-02-10
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US6818202B2 (en) 2004-11-16
IL126347A0 (en) 1999-05-09
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FI982069A0 (fi) 1998-09-25
US6426058B1 (en) 2002-07-30
WO1997037239A1 (en) 1997-10-09
US20020094317A1 (en) 2002-07-18
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