IL126082A0 - Compositions for alleviating neuropathic pain comprising prosaposin-derived peptides - Google Patents
Compositions for alleviating neuropathic pain comprising prosaposin-derived peptidesInfo
- Publication number
- IL126082A0 IL126082A0 IL12608297A IL12608297A IL126082A0 IL 126082 A0 IL126082 A0 IL 126082A0 IL 12608297 A IL12608297 A IL 12608297A IL 12608297 A IL12608297 A IL 12608297A IL 126082 A0 IL126082 A0 IL 126082A0
- Authority
- IL
- Israel
- Prior art keywords
- prosaposin
- neuropathic pain
- compositions
- derived peptides
- alleviating neuropathic
- Prior art date
Links
- 102100036197 Prosaposin Human genes 0.000 title abstract 3
- 101710152403 Prosaposin Proteins 0.000 title abstract 3
- 208000004296 neuralgia Diseases 0.000 title abstract 3
- 208000021722 neuropathic pain Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/611,307 US6271196B1 (en) | 1996-03-05 | 1996-03-05 | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
| PCT/US1997/004143 WO1997032895A1 (en) | 1996-03-05 | 1997-03-05 | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL126082A0 true IL126082A0 (en) | 1999-05-09 |
Family
ID=24448513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12608297A IL126082A0 (en) | 1996-03-05 | 1997-03-05 | Compositions for alleviating neuropathic pain comprising prosaposin-derived peptides |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6271196B1 (enExample) |
| EP (1) | EP0929569B1 (enExample) |
| JP (1) | JP4138006B2 (enExample) |
| KR (1) | KR100507715B1 (enExample) |
| AT (1) | ATE340187T1 (enExample) |
| AU (1) | AU734566B2 (enExample) |
| CA (1) | CA2248139C (enExample) |
| CZ (1) | CZ297384B6 (enExample) |
| DE (1) | DE69736712T2 (enExample) |
| IL (1) | IL126082A0 (enExample) |
| NO (1) | NO984093L (enExample) |
| NZ (1) | NZ331757A (enExample) |
| PL (1) | PL187917B1 (enExample) |
| RU (2) | RU2266129C2 (enExample) |
| SK (1) | SK122898A3 (enExample) |
| WO (1) | WO1997032895A1 (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571787A (en) * | 1993-07-30 | 1996-11-05 | Myelos Corporation | Prosaposin as a neurotrophic factor |
| US6849602B1 (en) * | 1996-03-05 | 2005-02-01 | The Regents Of The University Of California | Compositions for alleviating neuropathic pain with prosaposin receptor agonists |
| JP2001524944A (ja) * | 1997-03-05 | 2001-12-04 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 神経障害性疼痛の緩和方法 |
| WO1998039357A1 (en) * | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Method of alleviating neuropathic pain |
| CA2284105A1 (en) * | 1997-03-24 | 1998-10-01 | John S. O'brien | Synthetic saposin c-derived neurotrophic peptides |
| CA2304108A1 (en) * | 1997-09-09 | 1999-03-18 | The Regents Of The University Of California | Inhibition of apoptotis using prosaposin receptor agonists |
| US6458357B1 (en) * | 1997-09-09 | 2002-10-01 | Myelos Corporation | Retro-inverso neurotrophic and analgesic peptides |
| CZ2001655A3 (cs) * | 1998-08-28 | 2001-11-14 | Myelos Corporation | Cyklický peptid, prostředek, způsob indukce myelinizace, způsob potlačení degenerace neuronů a způsob léčby |
| US20020028783A1 (en) * | 1999-09-09 | 2002-03-07 | O'brien John S. | Method of stimulating prosaposin receptor activity |
| USRE45976E1 (en) * | 1999-02-24 | 2016-04-19 | Tact Ip, Llc | Methods of inhibiting the action of TNF for neurological conditions by administering etanercept intrathecally |
| WO2000058359A1 (en) * | 1999-03-30 | 2000-10-05 | Myelos Corporation | Retro-inverso prosaposin-derived peptides and use thereof |
| US7345019B1 (en) | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7309687B1 (en) | 1999-04-13 | 2007-12-18 | The Kenneth S. Warren Institute, Inc. | Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin |
| US7109168B1 (en) | 2000-06-16 | 2006-09-19 | Myelos Corporation | Retro-inverso peptides derived from leukemia inhibitory factor |
| US7135461B1 (en) | 2000-06-16 | 2006-11-14 | Myelos Corporation | Retro-inverso peptides derived from interleukin-6 |
| AU5496500A (en) * | 1999-06-16 | 2001-01-02 | Myelos Corporation | Retro-inverso peptides derived from interleukin-3 |
| IL147095A0 (en) * | 1999-06-16 | 2002-08-14 | Myelos Corp | Retro-inverso peptides derived from leukemia inhibitory factor |
| CA2376479A1 (en) * | 1999-06-16 | 2000-12-21 | David E. Wright | Retro-inverso peptides derived from interleukin-6 |
| US20050074747A1 (en) * | 2000-09-08 | 2005-04-07 | Wadih Arap | Biopanning and rapid analysis of selective interactive ligands (brasil) |
| US7420030B2 (en) | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
| US20040170955A1 (en) * | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
| US7452964B2 (en) | 2001-09-07 | 2008-11-18 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides against placenta and adipose tissues |
| US6531121B2 (en) | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20060287240A1 (en) * | 2001-03-09 | 2006-12-21 | O'brien John S | Method of stimulating prosaposin receptor activity |
| US20040176290A1 (en) * | 2001-07-18 | 2004-09-09 | Renata Pasqualini | Anti-angiogenic state in mice and humans with retinal photorecptor cell degeneration |
| US8507445B2 (en) * | 2001-09-07 | 2013-08-13 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| US20040048243A1 (en) * | 2001-09-07 | 2004-03-11 | Wadih Arap | Methods and compositions for in vitro targeting |
| US7671010B2 (en) * | 2002-08-30 | 2010-03-02 | The Board Of Regents Of The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| AU2003259846A1 (en) * | 2002-08-16 | 2004-03-03 | The General Hospital Corporation | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US7166691B2 (en) * | 2002-12-20 | 2007-01-23 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Saposin C and receptors as targets for treatment of benign and malignant disorders |
| WO2004084930A1 (en) * | 2003-03-26 | 2004-10-07 | Develogen Aktiengesellschaft | Use of saposin-related proteins for preventing and treating obesity, diabetes and/or metabolic syndrome |
| EP1613321A2 (en) * | 2003-03-28 | 2006-01-11 | Acadia Pharmaceuticals Inc. | Muscarinic m1 receptor agonists for pain management |
| US7834147B2 (en) * | 2003-04-28 | 2010-11-16 | Childrens Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
| CN100366286C (zh) * | 2003-04-28 | 2008-02-06 | 常州南云科技有限公司 | Saposin C-DOPS:一种抗癌新药 |
| US9345745B2 (en) * | 2005-04-29 | 2016-05-24 | Bo Wang | Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides |
| EP1736481A1 (en) * | 2005-05-13 | 2006-12-27 | Charite Universitätsmedizin-Berlin | Erythropoietin variants |
| RU2317829C2 (ru) * | 2005-10-05 | 2008-02-27 | Федеральное государственное учреждение науки "Екатеринбургский медицинский научный центр профилактики и охраны здоровья рабочих промпредприятий" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Способ лечения мононевропатий верхних конечностей |
| US7964585B2 (en) * | 2006-03-14 | 2011-06-21 | Case Western Reserve University | Composition and method of treating peripheral neuropathy |
| RU2345786C2 (ru) * | 2007-02-27 | 2009-02-10 | Андрей Евгеньевич Кульчиков | Способ лечения непрерывно-прогредиентных дегенеративных и демиелинизирующих заболеваний |
| KR20180123731A (ko) | 2008-01-22 | 2018-11-19 | 아라임 파마슈티칼즈, 인크. | 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체 |
| RU2561582C2 (ru) * | 2010-11-19 | 2015-08-27 | Российская Федерация в лице Министерства промышленности и торговли Российской Федерации | Инъекционная лекарственная форма олигопептидного препарата для лечения рассеянного склероза и способ ее получения |
| WO2012115185A1 (ja) * | 2011-02-23 | 2012-08-30 | 北海道公立大学法人札幌医科大学 | 疼痛を治療、改善、または予防するための組成物 |
| RU2669692C1 (ru) * | 2017-08-14 | 2018-10-15 | Павел Андреевич Канаев | Способ получения комплекса биологически активных пептидов обладающих нейротропной активностью |
| BR112020018334A2 (pt) | 2018-03-23 | 2021-02-17 | Bexion Pharmaceuticals Inc. | composições farmacêuticas de saposina c e métodos de tratamento de câncer |
| SG11202007887VA (en) | 2018-03-29 | 2020-09-29 | Lateral IP Pty Ltd | Cyclic peptides and uses thereof |
| EP4274657A4 (en) * | 2021-01-09 | 2024-12-11 | Bexion Pharmaceuticals, Inc. | METHODS FOR REDUCING NEUROPATHY AND NEUROPATHIC SYMPTOMS AND TREATING CANCER |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3750197D1 (de) | 1986-04-22 | 1994-08-18 | Salk Inst For Biological Studi | Antagonisten des Fibroblasten-Wachstumsfaktors. |
| DD298412A5 (de) * | 1989-04-28 | 1992-02-20 | ������@���Kk�� | Verfahren zur herstellung von polypeptiden, die geeignet sind als antagonisten exzitatorischer aminosaeure-neurotransmitter und/oder blocker der calciumkanaele |
| US5169764A (en) * | 1990-08-08 | 1992-12-08 | Regeneron Pharmaceuticals, Inc. | Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| RU2007417C1 (ru) * | 1991-06-21 | 1994-02-15 | Российский государственный медицинский университет | Способ получения плацентарного протеина |
| WO1993015722A1 (en) | 1992-02-07 | 1993-08-19 | Syntex (Usa) Inc. | Controlled delivery of pharmaceuticals from preformed porous microparticles |
| US5534495A (en) * | 1993-05-25 | 1996-07-09 | Advanced Peptides And Biotechnology Sciences | Treatment of non-HIV neuropathic pain syndromes |
| US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
| US5571787A (en) | 1993-07-30 | 1996-11-05 | Myelos Corporation | Prosaposin as a neurotrophic factor |
| CA2176708A1 (en) * | 1993-11-15 | 1995-05-26 | Christopher A. Maack | Method of treating neurological disorders |
| WO1998039357A1 (en) * | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Method of alleviating neuropathic pain |
| CA2284105A1 (en) * | 1997-03-24 | 1998-10-01 | John S. O'brien | Synthetic saposin c-derived neurotrophic peptides |
-
1996
- 1996-03-05 US US08/611,307 patent/US6271196B1/en not_active Expired - Fee Related
-
1997
- 1997-03-05 CZ CZ0283998A patent/CZ297384B6/cs not_active IP Right Cessation
- 1997-03-05 JP JP53205097A patent/JP4138006B2/ja not_active Expired - Fee Related
- 1997-03-05 PL PL32870197A patent/PL187917B1/pl not_active IP Right Cessation
- 1997-03-05 NZ NZ331757A patent/NZ331757A/en active IP Right Revival
- 1997-03-05 IL IL12608297A patent/IL126082A0/xx unknown
- 1997-03-05 AU AU23286/97A patent/AU734566B2/en not_active Ceased
- 1997-03-05 DE DE69736712T patent/DE69736712T2/de not_active Expired - Fee Related
- 1997-03-05 EP EP97916005A patent/EP0929569B1/en not_active Expired - Lifetime
- 1997-03-05 KR KR1019980707151A patent/KR100507715B1/ko not_active Expired - Fee Related
- 1997-03-05 AT AT97916005T patent/ATE340187T1/de not_active IP Right Cessation
- 1997-03-05 SK SK1228-98A patent/SK122898A3/sk unknown
- 1997-03-05 RU RU2003131695/14A patent/RU2266129C2/ru not_active IP Right Cessation
- 1997-03-05 WO PCT/US1997/004143 patent/WO1997032895A1/en not_active Ceased
- 1997-03-05 CA CA002248139A patent/CA2248139C/en not_active Expired - Fee Related
- 1997-03-05 RU RU98118091/04A patent/RU2223969C2/ru not_active IP Right Cessation
-
1998
- 1998-09-04 NO NO984093A patent/NO984093L/no not_active Application Discontinuation
-
1999
- 1999-01-15 US US09/231,159 patent/US6268347B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE340187T1 (de) | 2006-10-15 |
| RU2003131695A (ru) | 2005-04-10 |
| SK122898A3 (en) | 2000-02-14 |
| WO1997032895A1 (en) | 1997-09-12 |
| CA2248139C (en) | 2004-05-18 |
| NZ331757A (en) | 1999-10-28 |
| PL328701A1 (en) | 1999-02-15 |
| KR19990087686A (ko) | 1999-12-27 |
| DE69736712D1 (de) | 2006-11-02 |
| US6268347B1 (en) | 2001-07-31 |
| AU734566B2 (en) | 2001-06-14 |
| RU2223969C2 (ru) | 2004-02-20 |
| PL187917B1 (pl) | 2004-11-30 |
| CA2248139A1 (en) | 1997-09-12 |
| CZ297384B6 (cs) | 2006-11-15 |
| KR100507715B1 (ko) | 2006-05-26 |
| RU2266129C2 (ru) | 2005-12-20 |
| CZ283998A3 (cs) | 1999-05-12 |
| JP2000506853A (ja) | 2000-06-06 |
| DE69736712T2 (de) | 2007-09-13 |
| EP0929569A1 (en) | 1999-07-21 |
| EP0929569B1 (en) | 2006-09-20 |
| NO984093D0 (no) | 1998-09-04 |
| US6271196B1 (en) | 2001-08-07 |
| EP0929569A4 (en) | 2000-08-23 |
| JP4138006B2 (ja) | 2008-08-20 |
| NO984093L (no) | 1998-11-04 |
| AU2328697A (en) | 1997-09-22 |
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