IL125974A0 - 2-thioxotetrahydropyrimidin-4-one derivatives - Google Patents
2-thioxotetrahydropyrimidin-4-one derivativesInfo
- Publication number
- IL125974A0 IL125974A0 IL12597497A IL12597497A IL125974A0 IL 125974 A0 IL125974 A0 IL 125974A0 IL 12597497 A IL12597497 A IL 12597497A IL 12597497 A IL12597497 A IL 12597497A IL 125974 A0 IL125974 A0 IL 125974A0
- Authority
- IL
- Israel
- Prior art keywords
- thioxotetrahydropyrimidin
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1299396P | 1996-03-07 | 1996-03-07 | |
| PCT/US1997/002281 WO1997032855A1 (fr) | 1996-03-07 | 1997-02-12 | Derives de la 2-thioxotetrahydropyrimidin-4-one |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL125974A0 true IL125974A0 (en) | 1999-04-11 |
Family
ID=21757747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12597497A IL125974A0 (en) | 1996-03-07 | 1997-02-12 | 2-thioxotetrahydropyrimidin-4-one derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5807864A (fr) |
| EP (1) | EP0885197A1 (fr) |
| JP (1) | JP2000507926A (fr) |
| KR (1) | KR19990087582A (fr) |
| CN (1) | CN1217715A (fr) |
| AR (1) | AR005986A1 (fr) |
| AU (1) | AU707732B2 (fr) |
| BR (1) | BR9708310A (fr) |
| CA (1) | CA2247933A1 (fr) |
| HU (1) | HUP9901968A3 (fr) |
| IL (1) | IL125974A0 (fr) |
| NZ (1) | NZ332199A (fr) |
| TW (1) | TW422840B (fr) |
| WO (1) | WO1997032855A1 (fr) |
| ZA (1) | ZA971911B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001503769A (ja) * | 1996-11-14 | 2001-03-21 | アメリカン・ホーム・プロダクツ・コーポレイション | 抗アテローム性動脈硬化症薬としての置換テトラヒドロ―１，３，５―トリアジン―２［１ｈ］―チオン |
| AU2001294910A1 (en) | 2000-10-02 | 2002-04-15 | American Home Products Corporation | 3-thioxo-(1,2,4)-oxadiazinan-5-one and their use as anti-antherosclerotic agents |
| US20050096319A1 (en) * | 2003-02-21 | 2005-05-05 | Balzarini Jan M.R. | Identification of compounds that inhibit replication of human immunodeficiency virus |
| CN102423314A (zh) * | 2011-11-26 | 2012-04-25 | 济南环肽医药科技有限公司 | 一种治疗免疫性肝损伤或免疫性肝纤维化的药物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55108858A (en) * | 1979-02-14 | 1980-08-21 | Kyowa Hakko Kogyo Co Ltd | Novel dihydrouracil derivative and herbicide |
| JPS5939875A (ja) * | 1982-08-31 | 1984-03-05 | Sagami Chem Res Center | ５−トリフルオロメチルジヒドロウラシル類の製造方法 |
| JPS60243017A (ja) * | 1984-05-16 | 1985-12-03 | Kyowa Hakko Kogyo Co Ltd | 抗けいれん組成物 |
| JPH0651682B2 (ja) * | 1986-09-05 | 1994-07-06 | 株式会社上野製薬応用研究所 | ウラシル誘導体の製造方法 |
| US4927451A (en) * | 1988-12-30 | 1990-05-22 | Uniroyal Chemical Company, Inc. | 3-aryldihydrouracils |
| DE4318550A1 (de) * | 1993-06-04 | 1994-12-08 | Boehringer Mannheim Gmbh | Aryliden-4-oxo-2-thioxo-3- thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US5554607A (en) * | 1995-11-28 | 1996-09-10 | American Home Products Corporation | Use of 2-thioxo-imidazolin-4-one derivatives in the treatment of atherosclerosis |
-
1997
- 1997-02-12 AU AU21237/97A patent/AU707732B2/en not_active Ceased
- 1997-02-12 CA CA002247933A patent/CA2247933A1/fr not_active Abandoned
- 1997-02-12 IL IL12597497A patent/IL125974A0/xx unknown
- 1997-02-12 KR KR1019980707023A patent/KR19990087582A/ko not_active Application Discontinuation
- 1997-02-12 JP JP9531771A patent/JP2000507926A/ja active Pending
- 1997-02-12 CN CN97194335A patent/CN1217715A/zh active Pending
- 1997-02-12 EP EP97906583A patent/EP0885197A1/fr not_active Withdrawn
- 1997-02-12 HU HU9901968A patent/HUP9901968A3/hu unknown
- 1997-02-12 WO PCT/US1997/002281 patent/WO1997032855A1/fr not_active Application Discontinuation
- 1997-02-12 NZ NZ332199A patent/NZ332199A/en unknown
- 1997-02-12 BR BR9708310A patent/BR9708310A/pt not_active Application Discontinuation
- 1997-02-20 TW TW086102010A patent/TW422840B/zh active
- 1997-02-24 AR ARP970100745A patent/AR005986A1/es unknown
- 1997-02-27 US US08/807,164 patent/US5807864A/en not_active Expired - Lifetime
- 1997-03-05 ZA ZA971911A patent/ZA971911B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ332199A (en) | 1999-03-29 |
| AU707732B2 (en) | 1999-07-15 |
| BR9708310A (pt) | 1999-08-03 |
| ZA971911B (en) | 1998-09-07 |
| CN1217715A (zh) | 1999-05-26 |
| JP2000507926A (ja) | 2000-06-27 |
| AU2123797A (en) | 1997-09-22 |
| KR19990087582A (ko) | 1999-12-27 |
| WO1997032855A1 (fr) | 1997-09-12 |
| AR005986A1 (es) | 1999-07-21 |
| EP0885197A1 (fr) | 1998-12-23 |
| HUP9901968A2 (hu) | 1999-10-28 |
| CA2247933A1 (fr) | 1997-09-12 |
| HUP9901968A3 (en) | 2000-01-28 |
| TW422840B (en) | 2001-02-21 |
| US5807864A (en) | 1998-09-15 |
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