IL122296A0 - Quinolizinone type compounds - Google Patents
Quinolizinone type compoundsInfo
- Publication number
- IL122296A0 IL122296A0 IL12229696A IL12229696A IL122296A0 IL 122296 A0 IL122296 A0 IL 122296A0 IL 12229696 A IL12229696 A IL 12229696A IL 12229696 A IL12229696 A IL 12229696A IL 122296 A0 IL122296 A0 IL 122296A0
- Authority
- IL
- Israel
- Prior art keywords
- type compounds
- quinolizinone
- quinolizinone type
- compounds
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46915995A | 1995-06-06 | 1995-06-06 | |
| US63811296A | 1996-05-29 | 1996-05-29 | |
| PCT/US1996/008991 WO1996039407A1 (fr) | 1995-06-06 | 1996-06-05 | Composes de type quinolizinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL122296A0 true IL122296A0 (en) | 1998-04-05 |
Family
ID=27042662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12229696A IL122296A0 (en) | 1995-06-06 | 1996-06-05 | Quinolizinone type compounds |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0871628A1 (fr) |
| JP (1) | JPH11510478A (fr) |
| KR (1) | KR19990022524A (fr) |
| AU (1) | AU6153096A (fr) |
| CA (1) | CA2222322A1 (fr) |
| IL (1) | IL122296A0 (fr) |
| MX (1) | MX9709416A (fr) |
| WO (1) | WO1996039407A1 (fr) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000516210A (ja) | 1996-07-12 | 2000-12-05 | ロイコサイト，インコーポレーテッド | ケモカインレセプターアンタゴニストとその使用方法 |
| US5693813A (en) * | 1997-02-26 | 1997-12-02 | Abbott Laboratories | Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid |
| KR100241673B1 (ko) * | 1997-08-09 | 2000-03-02 | 김충섭 | 퀴놀리진 카르복실산 유도체 |
| HUP0100051A3 (en) | 1997-09-15 | 2002-08-28 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
| WO2000017197A1 (fr) * | 1998-09-21 | 2000-03-30 | Biochem Pharma Inc. | Quinolizinones inhibiteurs de l'integrine |
| EP1134219B1 (fr) | 1998-11-24 | 2005-06-15 | Daiichi Pharmaceutical Co., Ltd. | Derives d'aminomethylpyrrolidine substitues par des cycloalkyles |
| EP2275141A1 (fr) | 1999-03-17 | 2011-01-19 | Daiichi Pharmaceutical Co., Ltd. | Compositions pharmaceutiques au gout camoufle |
| MXPA02005884A (es) * | 1999-12-14 | 2002-10-23 | Neurosearch As | Heteroaril-diazabicicloalcanos novedosos. |
| DE19962470A1 (de) * | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Verwendung von Chemotherapeutika |
| SE0100326D0 (sv) * | 2001-02-02 | 2001-02-02 | Astrazeneca Ab | New compounds |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP4101754B2 (ja) * | 2001-09-28 | 2008-06-18 | 佐藤製薬株式会社 | ２−ピリドン骨格を部分構造として有する４−オキソキノリジン抗菌剤 |
| US6900224B2 (en) * | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| AU2004278320B2 (en) * | 2003-09-22 | 2010-06-24 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| EP1693364B1 (fr) | 2003-12-12 | 2015-05-20 | Daiichi Sankyo Company, Limited | Intermediaires destines a la production de derives de cyclopropylamine optiquement actifs et processus de production de ces intermediaires |
| US7977346B2 (en) | 2006-01-17 | 2011-07-12 | Guoqing Paul Chen | Spiro compounds and methods of use |
| MX2008012328A (es) | 2006-03-28 | 2008-10-09 | Procter & Gamble | Sales de malato, y polimorfos de acido (3s,5s)-7-[3-amino-5-metil- piperidinil]-1-ciclopropil-1,4-dihidro-8-metoxi-4-oxo-3-quinolinc arboxilico. |
| KR101084521B1 (ko) | 2006-03-28 | 2011-11-18 | 워너 칠콧 컴퍼니 엘엘씨 | 퀴놀론 중간체를 제조하기 위한 커플링 방법 |
| ES2428344T3 (es) * | 2007-01-05 | 2013-11-07 | Daiichi Sankyo Company, Limited | Derivado de aminopirrolidina sustituido fusionado |
| CN101622240B (zh) * | 2007-01-05 | 2014-07-23 | 第一三共株式会社 | 稠合取代氨基吡咯烷衍生物 |
| WO2009081789A1 (fr) | 2007-12-26 | 2009-07-02 | Banyu Pharmaceutical Co., Ltd. | Dérivé de noyau à six chaînons à substitution sulphonyle |
| JP5433992B2 (ja) * | 2008-06-26 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロクロマノール誘導体の製造方法 |
| JP5433996B2 (ja) * | 2008-07-10 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロフェノール誘導体の製造方法 |
| EP2423211B1 (fr) * | 2009-04-20 | 2014-04-16 | Kaneka Corporation | Procédés de production de (1s,6s)- ou (1r,6r)-cis-2,8-diazabicyclo[4.3.0]nonane et leur intermédiaire |
| US8796297B2 (en) | 2009-06-30 | 2014-08-05 | Abbvie Inc. | 4-substituted-2-amino-pyrimidine derivatives |
| WO2011031745A1 (fr) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Analogues de fluoroquinolone antibactériens |
| JP5487425B2 (ja) * | 2009-09-11 | 2014-05-07 | 毅 野田 | 光学活性２−置換−３−アミノピペリジン誘導体および製造方法 |
| TR201910327T4 (tr) | 2009-10-23 | 2019-07-22 | Janssen Pharmaceutica Nv | Oreksin reseptör modülatörleri olarak di-ornatılmış oktahidropirrolo [3,4-c]pirroller. |
| ES2697174T3 (es) | 2012-02-10 | 2019-01-22 | Ptc Therapeutics Inc | Compuestos para tratar atrofia muscular espinal |
| WO2016196386A1 (fr) | 2015-05-30 | 2016-12-08 | Ptc Therapeutics, Inc. | Procédés de modulation de l'épissage de l'arn |
| DK3386511T3 (da) | 2015-12-10 | 2021-07-05 | Ptc Therapeutics Inc | Fremgangsmåder til behandling af huntingtons sygdom |
| SI3426251T1 (sl) | 2016-03-10 | 2022-07-29 | Janssen Pharmaceutica Nv | Postopki za zdravljenje depresije z antagonisti receptorja oreksina-2 |
| CN106543170B (zh) * | 2016-10-27 | 2018-02-23 | 丹诺医药(苏州）有限公司 | 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其合成方法 |
| JP2019535789A (ja) | 2016-11-28 | 2019-12-12 | ピーティーシー セラピューティクス，インコーポレーテッド | Ｒｎａスプライシングを調節する方法 |
| EP3634953B1 (fr) | 2017-06-05 | 2024-01-03 | PTC Therapeutics, Inc. | Composés permettant de traiter la maladie de huntington |
| EA202090034A1 (ru) | 2017-06-14 | 2020-04-16 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Способы модификации сплайсинга рнк |
| EP3645121A4 (fr) | 2017-06-28 | 2021-03-17 | PTC Therapeutics, Inc. | Méthodes de traitement de la maladie de huntington |
| WO2019005980A1 (fr) | 2017-06-28 | 2019-01-03 | Ptc Therapeutics, Inc. | Procédés de traitement de la maladie de huntington |
| BR112020019373A2 (pt) | 2018-03-27 | 2020-12-29 | Ptc Therapeutics, Inc. | Compostos para o tratamento da doença de hutington |
| AU2019294478B2 (en) | 2018-06-27 | 2023-03-23 | Ptc Therapeutics, Inc. | Heterocyclic and heteroaryl compounds for treating Huntington's disease |
| US11685746B2 (en) | 2018-06-27 | 2023-06-27 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating Huntington's disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE911472A1 (en) * | 1990-05-02 | 1991-11-06 | Abbott Lab | Quinolizinone type compounds |
| DE69430581D1 (de) * | 1993-10-14 | 2002-06-13 | Abbott Lab | Verbindungen des chinolizinon-typs |
-
1996
- 1996-06-05 IL IL12229696A patent/IL122296A0/xx unknown
- 1996-06-05 EP EP96919103A patent/EP0871628A1/fr not_active Withdrawn
- 1996-06-05 CA CA002222322A patent/CA2222322A1/fr not_active Abandoned
- 1996-06-05 AU AU61530/96A patent/AU6153096A/en not_active Abandoned
- 1996-06-05 KR KR1019970709005A patent/KR19990022524A/ko not_active Application Discontinuation
- 1996-06-05 JP JP9501420A patent/JPH11510478A/ja active Pending
- 1996-06-05 WO PCT/US1996/008991 patent/WO1996039407A1/fr not_active Application Discontinuation
-
1997
- 1997-12-02 MX MX9709416A patent/MX9709416A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2222322A1 (fr) | 1996-12-12 |
| KR19990022524A (ko) | 1999-03-25 |
| EP0871628A1 (fr) | 1998-10-21 |
| WO1996039407A1 (fr) | 1996-12-12 |
| MX9709416A (es) | 1998-07-31 |
| JPH11510478A (ja) | 1999-09-14 |
| AU6153096A (en) | 1996-12-24 |
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