IL118410A0 - Substituted camptothecin derivatives their preparation and pharmaceutical compositions containing them - Google Patents

Substituted camptothecin derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL118410A0
IL118410A0 IL11841096A IL11841096A IL118410A0 IL 118410 A0 IL118410 A0 IL 118410A0 IL 11841096 A IL11841096 A IL 11841096A IL 11841096 A IL11841096 A IL 11841096A IL 118410 A0 IL118410 A0 IL 118410A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
camptothecin derivatives
substituted camptothecin
Prior art date
Application number
IL11841096A
Other languages
English (en)
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of IL118410A0 publication Critical patent/IL118410A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
IL11841096A 1995-05-26 1996-05-23 Substituted camptothecin derivatives their preparation and pharmaceutical compositions containing them IL118410A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9510716.5A GB9510716D0 (en) 1995-05-26 1995-05-26 Substituted camptothecin derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
IL118410A0 true IL118410A0 (en) 1996-09-12

Family

ID=10775098

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11841096A IL118410A0 (en) 1995-05-26 1996-05-23 Substituted camptothecin derivatives their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US5856333A (xx)
EP (1) EP0777670B1 (xx)
JP (1) JPH10503220A (xx)
CN (1) CN1159192A (xx)
AR (1) AR003126A1 (xx)
AT (1) ATE262532T1 (xx)
AU (1) AU5817996A (xx)
BR (1) BR9606396A (xx)
CA (1) CA2194700A1 (xx)
DE (1) DE69631943D1 (xx)
GB (1) GB9510716D0 (xx)
HU (1) HUP9702400A3 (xx)
IL (1) IL118410A0 (xx)
NO (1) NO970293L (xx)
NZ (1) NZ308514A (xx)
PL (1) PL318279A1 (xx)
WO (1) WO1996037496A1 (xx)
ZA (1) ZA964138B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096336A (en) * 1996-01-30 2000-08-01 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
GB9702807D0 (en) 1997-02-12 1997-04-02 Pharmacia & Upjohn Spa Alkynyl-substituted camptothecins and process for their preparation
WO1998035940A1 (en) * 1997-02-14 1998-08-20 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
WO1998051684A1 (en) 1997-05-15 1998-11-19 Eli Lilly And Company Antithrombotic compound
HUP9701554D0 (en) * 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins
US6352996B1 (en) 1999-08-03 2002-03-05 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
US6228855B1 (en) 1999-08-03 2001-05-08 The Stehlin Foundation For Cancer Research Aromatic esters of camptothecins and methods to treat cancers
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US6288072B1 (en) * 1999-12-29 2001-09-11 Monroe E. Wall Camptothecin β-alanine esters with topoisomerase I inhibition
MXPA02008355A (es) 2000-02-28 2002-12-13 Aventis Pharma Sa Composicion que comprende camptotecina y derivado de pirimidina para tratamiento del cancer.
US6545010B2 (en) 2000-03-17 2003-04-08 Aventis Pharma S.A. Composition comprising camptothecin or a camptothecin derivative and a platin derivative for the treatment of cancer
US6548488B2 (en) 2000-03-17 2003-04-15 Aventis Pharma S.A. Composition comprising camptothecin or a camptothecin derivative and an alkylating agent for the treatment of cancer
US6486320B2 (en) 2000-09-15 2002-11-26 Aventis Pharma S.A. Preparation of camptothecin and of its derivatives
EE200300184A (et) 2000-10-27 2003-08-15 Aventis Pharma S.A. Farmatseutiline kompositsioon, mis sisaldab kamptotetsiini kombinatsioonis stilbeeni derivaadiga, ning selle kasutamine vähktõve raviks
RU2004132721A (ru) 2002-04-08 2005-06-27 Глэксо Груп Лимитед (GB) (2-алкокси)фенил)циклопент-1-енил)ароматическая карбо- и гетероциклическая карбоновая кислота и ее производные
GB0225548D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Compounds
CN100406460C (zh) * 2003-11-10 2008-07-30 中国科学院上海药物研究所 喜树碱的新衍生物、制备方法和用途
US20090104254A1 (en) 2004-12-22 2009-04-23 Rutgers, The State University Of New Jersey Controlled Release Hydrogels
US8410045B2 (en) 2006-03-30 2013-04-02 Drais Pharmaceuticals, Inc. Camptothecin-peptide conjugates and pharmaceutical compositions containing the same
CN101880285B (zh) * 2010-06-24 2012-07-04 华东师范大学 一种烯丙基取代喜树碱化合物的合成方法
US20140086975A1 (en) 2010-10-15 2014-03-27 Rutgers, The State University Of New Jersey Hydrogel formulation for dermal and ocular delivery
CN104774209B (zh) * 2014-01-15 2018-06-19 上海海和药物研究开发有限公司 一种9-烯丙基喜树碱衍生物的合成方法
AR125473A1 (es) 2021-04-29 2023-07-19 Abbvie Inc Conjugados de anticuerpo anti-c-met y fármaco

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364858A (en) * 1987-03-31 1994-11-15 Research Triangle Institute Camptothecin analogs as potent inhibitors of topoisomerase I
US5122606A (en) * 1987-04-14 1992-06-16 Research Triangle Institute 10,11-methylenedioxy camptothecins
US5340817A (en) * 1987-04-14 1994-08-23 Research Triangle Institute Method of treating tumors with anti-tumor effective camptothecin compounds
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JPH0615547B2 (ja) * 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
WO1991004260A2 (en) * 1989-09-15 1991-04-04 Research Triangle Institute 10,11-methylenedioxy-20(rs)-camptothecin and 10,11-methylenedioxy-20(s)-camptothecin analogs
GB9319944D0 (en) * 1993-09-28 1993-11-17 Erba Carlo Spa Process for the preparation of 9-amino camptothecin
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation

Also Published As

Publication number Publication date
AU5817996A (en) 1996-12-11
AR003126A1 (es) 1998-07-08
EP0777670A1 (en) 1997-06-11
NO970293L (no) 1997-03-06
HUP9702400A2 (hu) 1998-06-29
PL318279A1 (en) 1997-06-09
ZA964138B (en) 1996-11-27
GB9510716D0 (en) 1995-07-19
WO1996037496A1 (en) 1996-11-28
CA2194700A1 (en) 1996-11-28
HUP9702400A3 (en) 1998-07-28
EP0777670B1 (en) 2004-03-24
JPH10503220A (ja) 1998-03-24
NO970293D0 (no) 1997-01-23
BR9606396A (pt) 1997-10-14
US5856333A (en) 1999-01-05
NZ308514A (en) 1998-06-26
DE69631943D1 (de) 2004-04-29
CN1159192A (zh) 1997-09-10
ATE262532T1 (de) 2004-04-15

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