IL118385A0 - Styryl benzimidazole derivatives and pharmaceutical compositions containing them - Google Patents
Styryl benzimidazole derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL118385A0 IL118385A0 IL11838596A IL11838596A IL118385A0 IL 118385 A0 IL118385 A0 IL 118385A0 IL 11838596 A IL11838596 A IL 11838596A IL 11838596 A IL11838596 A IL 11838596A IL 118385 A0 IL118385 A0 IL 118385A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- benzimidazole derivatives
- styryl
- styryl benzimidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/468,271 US6444694B1 (en) | 1995-06-06 | 1995-06-06 | Styryl benzimidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL118385A0 true IL118385A0 (en) | 1996-09-12 |
Family
ID=23859136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11838596A IL118385A0 (en) | 1995-06-06 | 1996-05-22 | Styryl benzimidazole derivatives and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6444694B1 (es) |
| EP (1) | EP0830345B1 (es) |
| JP (1) | JPH11506753A (es) |
| KR (1) | KR19990022266A (es) |
| CN (1) | CN1192206A (es) |
| AR (1) | AR002749A1 (es) |
| AT (1) | ATE205196T1 (es) |
| AU (1) | AU711965B2 (es) |
| BR (1) | BR9609153A (es) |
| CA (1) | CA2223585A1 (es) |
| DE (1) | DE69615023T2 (es) |
| DK (1) | DK0830345T3 (es) |
| ES (1) | ES2162063T3 (es) |
| HU (2) | HUP9900679A3 (es) |
| IL (1) | IL118385A0 (es) |
| NZ (1) | NZ309499A (es) |
| PT (1) | PT830345E (es) |
| WO (1) | WO1996039391A1 (es) |
| ZA (1) | ZA964693B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| US7098231B2 (en) | 2003-01-22 | 2006-08-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| EA200901463A1 (ru) | 2004-02-20 | 2010-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Ингибиторы вирусной полимеразы |
| WO2007019674A1 (en) | 2005-08-12 | 2007-02-22 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| KR101565271B1 (ko) | 2006-07-05 | 2015-11-02 | 피브로테크 세라퓨틱 피티와이 엘티디 | 치료 화합물 |
| EP2491030B1 (en) * | 2009-10-22 | 2015-07-15 | Fibrotech Therapeutics PTY LTD | Fused ring analogues of anti-fibrotic agents |
| WO2018144620A1 (en) | 2017-02-03 | 2018-08-09 | Shire Human Genetic Therapies, Inc. | Anti-fibrotic compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3575956A (en) * | 1967-07-24 | 1971-04-20 | Sterling Drug Inc | 2-substituted-benz-x-azol-6-ylazo-aminonaphthalene compounds |
| DE1670908A1 (de) * | 1967-08-16 | 1971-04-29 | Hoechst Ag | Neue Benzimidazolverbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung als optische Aufhellungsmittel |
| FR2104717A1 (en) * | 1970-09-28 | 1972-04-21 | Dynachim Sarl | Organophosphorus pesticides stabilised with benzimidazole derivs - - for controlling insects and internal parasites of animals |
| DE3505609A1 (de) | 1985-02-19 | 1986-08-21 | Merck Patent Gmbh, 6100 Darmstadt | Benzimidazolyl-pyridazinone |
| CA2080582A1 (en) | 1990-04-16 | 1991-10-17 | Alfred P. Spada | Heterocyclicethenediyl compounds which inhibit egf receptor tyrosine kinase |
| US5196446A (en) | 1990-04-16 | 1993-03-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Certain indole compounds which inhibit EGF receptor tyrosine kinase |
| DE4212748A1 (de) | 1992-04-16 | 1993-10-21 | Thomae Gmbh Dr K | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5387600A (en) | 1992-07-30 | 1995-02-07 | Fuji Photo Film Co., Ltd. | Treating arteriosclerosis using benzimidazole compositions |
-
1995
- 1995-06-06 US US08/468,271 patent/US6444694B1/en not_active Expired - Fee Related
-
1996
- 1996-05-22 IL IL11838596A patent/IL118385A0/xx unknown
- 1996-05-30 AR ARP960102799A patent/AR002749A1/es unknown
- 1996-06-03 KR KR1019970708745A patent/KR19990022266A/ko not_active Application Discontinuation
- 1996-06-03 DE DE69615023T patent/DE69615023T2/de not_active Expired - Fee Related
- 1996-06-03 CN CN96195860A patent/CN1192206A/zh active Pending
- 1996-06-03 PT PT96916978T patent/PT830345E/pt unknown
- 1996-06-03 EP EP96916978A patent/EP0830345B1/en not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/008375 patent/WO1996039391A1/en not_active Application Discontinuation
- 1996-06-03 AU AU59684/96A patent/AU711965B2/en not_active Ceased
- 1996-06-03 BR BR9609153A patent/BR9609153A/pt unknown
- 1996-06-03 HU HU9900679A patent/HUP9900679A3/hu unknown
- 1996-06-03 DK DK96916978T patent/DK0830345T3/da active
- 1996-06-03 ES ES96916978T patent/ES2162063T3/es not_active Expired - Lifetime
- 1996-06-03 JP JP9500994A patent/JPH11506753A/ja active Pending
- 1996-06-03 NZ NZ309499A patent/NZ309499A/xx unknown
- 1996-06-03 AT AT96916978T patent/ATE205196T1/de not_active IP Right Cessation
- 1996-06-03 HU HU9900914A patent/HUP9900914A2/hu unknown
- 1996-06-03 CA CA002223585A patent/CA2223585A1/en not_active Abandoned
- 1996-06-05 ZA ZA9604693A patent/ZA964693B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0830345T3 (da) | 2001-11-19 |
| ES2162063T3 (es) | 2001-12-16 |
| MX9709647A (es) | 1998-07-31 |
| HUP9900914A2 (hu) | 1999-07-28 |
| EP0830345B1 (en) | 2001-09-05 |
| CN1192206A (zh) | 1998-09-02 |
| US6444694B1 (en) | 2002-09-03 |
| HUP9900679A3 (en) | 2001-07-30 |
| WO1996039391A1 (en) | 1996-12-12 |
| ZA964693B (en) | 1997-12-05 |
| AR002749A1 (es) | 1998-04-29 |
| NZ309499A (en) | 2000-08-25 |
| AU711965B2 (en) | 1999-10-28 |
| HUP9900679A2 (hu) | 1999-09-28 |
| BR9609153A (pt) | 1999-05-04 |
| DE69615023D1 (de) | 2001-10-11 |
| KR19990022266A (ko) | 1999-03-25 |
| DE69615023T2 (de) | 2002-06-06 |
| EP0830345A1 (en) | 1998-03-25 |
| PT830345E (pt) | 2002-01-30 |
| JPH11506753A (ja) | 1999-06-15 |
| AU5968496A (en) | 1996-12-24 |
| CA2223585A1 (en) | 1996-12-12 |
| ATE205196T1 (de) | 2001-09-15 |
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