IL118385A0 - Styryl benzimidazole derivatives and pharmaceutical compositions containing them - Google Patents

Styryl benzimidazole derivatives and pharmaceutical compositions containing them

Info

Publication number
IL118385A0
IL118385A0 IL11838596A IL11838596A IL118385A0 IL 118385 A0 IL118385 A0 IL 118385A0 IL 11838596 A IL11838596 A IL 11838596A IL 11838596 A IL11838596 A IL 11838596A IL 118385 A0 IL118385 A0 IL 118385A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
benzimidazole derivatives
styryl
styryl benzimidazole
Prior art date
Application number
IL11838596A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL118385A0 publication Critical patent/IL118385A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL11838596A 1995-06-06 1996-05-22 Styryl benzimidazole derivatives and pharmaceutical compositions containing them IL118385A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/468,271 US6444694B1 (en) 1995-06-06 1995-06-06 Styryl benzimidazole derivatives

Publications (1)

Publication Number Publication Date
IL118385A0 true IL118385A0 (en) 1996-09-12

Family

ID=23859136

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11838596A IL118385A0 (en) 1995-06-06 1996-05-22 Styryl benzimidazole derivatives and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US6444694B1 (da)
EP (1) EP0830345B1 (da)
JP (1) JPH11506753A (da)
KR (1) KR19990022266A (da)
CN (1) CN1192206A (da)
AR (1) AR002749A1 (da)
AT (1) ATE205196T1 (da)
AU (1) AU711965B2 (da)
BR (1) BR9609153A (da)
CA (1) CA2223585A1 (da)
DE (1) DE69615023T2 (da)
DK (1) DK0830345T3 (da)
ES (1) ES2162063T3 (da)
HU (2) HUP9900679A3 (da)
IL (1) IL118385A0 (da)
NZ (1) NZ309499A (da)
PT (1) PT830345E (da)
WO (1) WO1996039391A1 (da)
ZA (1) ZA964693B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448281B1 (en) 2000-07-06 2002-09-10 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
DK1718608T3 (da) 2004-02-20 2013-10-14 Boehringer Ingelheim Int Virale polymeraseinhibitorer
US8076365B2 (en) 2005-08-12 2011-12-13 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
MX352516B (es) 2006-07-05 2017-04-06 Fibrotech Therapeutics Pty Ltd Compuestos terapeuticos.
CN102574843B (zh) * 2009-10-22 2015-06-17 法博太科制药有限公司 抗纤维化剂的稠环类似物
EP3577103A1 (en) 2017-02-03 2019-12-11 Certa Therapeutics Pty Ltd. Anti-fibrotic compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3575956A (en) * 1967-07-24 1971-04-20 Sterling Drug Inc 2-substituted-benz-x-azol-6-ylazo-aminonaphthalene compounds
DE1670908A1 (de) * 1967-08-16 1971-04-29 Hoechst Ag Neue Benzimidazolverbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung als optische Aufhellungsmittel
FR2104717A1 (en) * 1970-09-28 1972-04-21 Dynachim Sarl Organophosphorus pesticides stabilised with benzimidazole derivs - - for controlling insects and internal parasites of animals
DE3505609A1 (de) 1985-02-19 1986-08-21 Merck Patent Gmbh, 6100 Darmstadt Benzimidazolyl-pyridazinone
WO1991016305A1 (en) 1990-04-16 1991-10-31 Rhone-Poulenc Rorer International (Holdings), Inc. Heterocyclicethenediyl compounds which inhibit egf receptor tyrosine kinase
US5196446A (en) 1990-04-16 1993-03-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem Certain indole compounds which inhibit EGF receptor tyrosine kinase
DE4212748A1 (de) 1992-04-16 1993-10-21 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5387600A (en) 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions

Also Published As

Publication number Publication date
DE69615023D1 (de) 2001-10-11
WO1996039391A1 (en) 1996-12-12
MX9709647A (es) 1998-07-31
NZ309499A (en) 2000-08-25
HUP9900914A2 (hu) 1999-07-28
EP0830345B1 (en) 2001-09-05
HUP9900679A2 (hu) 1999-09-28
BR9609153A (pt) 1999-05-04
EP0830345A1 (en) 1998-03-25
DK0830345T3 (da) 2001-11-19
ZA964693B (en) 1997-12-05
AU5968496A (en) 1996-12-24
AR002749A1 (es) 1998-04-29
US6444694B1 (en) 2002-09-03
JPH11506753A (ja) 1999-06-15
CA2223585A1 (en) 1996-12-12
AU711965B2 (en) 1999-10-28
HUP9900679A3 (en) 2001-07-30
CN1192206A (zh) 1998-09-02
PT830345E (pt) 2002-01-30
KR19990022266A (ko) 1999-03-25
DE69615023T2 (de) 2002-06-06
ATE205196T1 (de) 2001-09-15
ES2162063T3 (es) 2001-12-16

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