IL116971A - 2R, 3R-epoxyhex-5-en-1-ol useful as an intermediate in the asymmetric synthesis of 3-substituted furanoside compounds - Google Patents
2R, 3R-epoxyhex-5-en-1-ol useful as an intermediate in the asymmetric synthesis of 3-substituted furanoside compoundsInfo
- Publication number
- IL116971A IL116971A IL11697192A IL11697192A IL116971A IL 116971 A IL116971 A IL 116971A IL 11697192 A IL11697192 A IL 11697192A IL 11697192 A IL11697192 A IL 11697192A IL 116971 A IL116971 A IL 116971A
- Authority
- IL
- Israel
- Prior art keywords
- epoxyhex
- useful
- compounds
- asymmetric synthesis
- substituted furanoside
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000011914 asymmetric synthesis Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000002243 furanoses Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
- C07C247/04—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
- C07C247/08—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/42—Halogenated unsaturated alcohols acyclic
- C07C33/423—Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/698,042 US5216145A (en) | 1991-05-10 | 1991-05-10 | Asymmetric synthesis of 3-substituted furanoside compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL116971A true IL116971A (en) | 1999-03-12 |
Family
ID=24803685
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11697192A IL116971A (en) | 1991-05-10 | 1992-05-06 | 2R, 3R-epoxyhex-5-en-1-ol useful as an intermediate in the asymmetric synthesis of 3-substituted furanoside compounds |
| IL101799A IL101799A (en) | 1991-05-10 | 1992-05-06 | Asymmetric Synthesis of 3-Transformed Furanocide Compounds |
| IL11697196A IL116971A0 (en) | 1991-05-10 | 1996-01-30 | 2r, 3r-epixyhex-5-en-1-ol useful as an intermediate in the asymmetric synthesis of 3-substituted furanoside compounds |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL101799A IL101799A (en) | 1991-05-10 | 1992-05-06 | Asymmetric Synthesis of 3-Transformed Furanocide Compounds |
| IL11697196A IL116971A0 (en) | 1991-05-10 | 1996-01-30 | 2r, 3r-epixyhex-5-en-1-ol useful as an intermediate in the asymmetric synthesis of 3-substituted furanoside compounds |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5216145A (ja) |
| EP (1) | EP0540807B1 (ja) |
| JP (1) | JPH05170782A (ja) |
| KR (1) | KR920021526A (ja) |
| CN (1) | CN1032062C (ja) |
| AT (1) | ATE132125T1 (ja) |
| AU (1) | AU657129B2 (ja) |
| CA (1) | CA2068226A1 (ja) |
| CZ (1) | CZ283306B6 (ja) |
| DE (1) | DE69207154T2 (ja) |
| DK (1) | DK0540807T3 (ja) |
| ES (1) | ES2083608T3 (ja) |
| FI (1) | FI922097A (ja) |
| GR (1) | GR3018671T3 (ja) |
| HU (1) | HU209838B (ja) |
| IE (1) | IE75888B1 (ja) |
| IL (3) | IL116971A (ja) |
| NO (1) | NO178113C (ja) |
| NZ (1) | NZ242639A (ja) |
| PH (1) | PH31630A (ja) |
| PL (1) | PL168588B1 (ja) |
| SK (1) | SK279311B6 (ja) |
| TW (1) | TW223068B (ja) |
| ZA (1) | ZA923350B (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216145A (en) * | 1991-05-10 | 1993-06-01 | American Cyanamid Company | Asymmetric synthesis of 3-substituted furanoside compounds |
| US5521294A (en) * | 1995-01-18 | 1996-05-28 | Eli Lilly And Company | 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides |
| EP1812457A1 (en) * | 2004-07-30 | 2007-08-01 | Pharmaessentia Corp. | STEREOSELECTIVE SYNTHESIS OF ß-NUCLEOSIDES |
| WO2006119347A1 (en) * | 2005-05-02 | 2006-11-09 | Pharmaessentia Corp. | STEREOSELECTIVE SYNTHESIS OF β-NUCLEOSIDES |
| US8193339B2 (en) * | 2007-11-06 | 2012-06-05 | Pharmaessentia Corp. | Synthesis of β-nucleosides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216145A (en) * | 1991-05-10 | 1993-06-01 | American Cyanamid Company | Asymmetric synthesis of 3-substituted furanoside compounds |
-
1991
- 1991-05-10 US US07/698,042 patent/US5216145A/en not_active Expired - Fee Related
-
1992
- 1992-03-16 DE DE69207154T patent/DE69207154T2/de not_active Expired - Fee Related
- 1992-03-16 AT AT92104485T patent/ATE132125T1/de not_active IP Right Cessation
- 1992-03-16 ES ES92104485T patent/ES2083608T3/es not_active Expired - Lifetime
- 1992-03-16 DK DK92104485.5T patent/DK0540807T3/da active
- 1992-03-16 EP EP92104485A patent/EP0540807B1/en not_active Expired - Lifetime
- 1992-03-17 TW TW081102018A patent/TW223068B/zh active
- 1992-04-11 CN CN92102690A patent/CN1032062C/zh not_active Expired - Fee Related
- 1992-05-06 JP JP4139628A patent/JPH05170782A/ja active Pending
- 1992-05-06 IL IL11697192A patent/IL116971A/xx not_active IP Right Cessation
- 1992-05-06 IL IL101799A patent/IL101799A/en not_active IP Right Cessation
- 1992-05-07 NZ NZ242639A patent/NZ242639A/en unknown
- 1992-05-07 CZ CS921386A patent/CZ283306B6/cs not_active IP Right Cessation
- 1992-05-07 SK SK1386-92A patent/SK279311B6/sk unknown
- 1992-05-08 FI FI922097A patent/FI922097A/fi unknown
- 1992-05-08 ZA ZA923350A patent/ZA923350B/xx unknown
- 1992-05-08 NO NO921837A patent/NO178113C/no not_active IP Right Cessation
- 1992-05-08 CA CA002068226A patent/CA2068226A1/en not_active Abandoned
- 1992-05-08 AU AU16132/92A patent/AU657129B2/en not_active Ceased
- 1992-05-08 HU HU9201546A patent/HU209838B/hu not_active IP Right Cessation
- 1992-05-08 PL PL92294479A patent/PL168588B1/pl unknown
- 1992-05-09 KR KR1019920007889A patent/KR920021526A/ko not_active Application Discontinuation
- 1992-07-01 IE IE921483A patent/IE75888B1/en not_active IP Right Cessation
-
1993
- 1993-03-12 US US08/031,304 patent/US5296620A/en not_active Expired - Lifetime
-
1995
- 1995-01-10 PH PH49766A patent/PH31630A/en unknown
-
1996
- 1996-01-16 GR GR950402590T patent/GR3018671T3/el unknown
- 1996-01-30 IL IL11697196A patent/IL116971A0/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |