IL116433A - INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS - Google Patents

INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS

Info

Publication number
IL116433A
IL116433A IL11643395A IL11643395A IL116433A IL 116433 A IL116433 A IL 116433A IL 11643395 A IL11643395 A IL 11643395A IL 11643395 A IL11643395 A IL 11643395A IL 116433 A IL116433 A IL 116433A
Authority
IL
Israel
Prior art keywords
oestradiol
precursor
moiety
group
drug delivery
Prior art date
Application number
IL11643395A
Other languages
English (en)
Other versions
IL116433A0 (en
Original Assignee
Galen Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galen Chemicals Ltd filed Critical Galen Chemicals Ltd
Publication of IL116433A0 publication Critical patent/IL116433A0/xx
Publication of IL116433A publication Critical patent/IL116433A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL11643395A 1994-12-19 1995-12-18 INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS IL116433A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IES940976 1994-12-19
IES950247 1995-04-05

Publications (2)

Publication Number Publication Date
IL116433A0 IL116433A0 (en) 1996-03-31
IL116433A true IL116433A (en) 2002-02-10

Family

ID=26319777

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11643395A IL116433A (en) 1994-12-19 1995-12-18 INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS

Country Status (19)

Country Link
US (1) US5855906A (xx)
EP (1) EP0799025B1 (xx)
JP (1) JPH10510825A (xx)
CN (1) CN1138526C (xx)
AR (1) AR002010A1 (xx)
AT (1) ATE178204T1 (xx)
AU (1) AU692659B2 (xx)
CA (1) CA2207622C (xx)
DE (1) DE69508791T2 (xx)
DK (1) DK0799025T3 (xx)
ES (1) ES2133841T3 (xx)
FI (1) FI119414B (xx)
GR (1) GR3030614T3 (xx)
IL (1) IL116433A (xx)
NO (1) NO316707B1 (xx)
NZ (1) NZ298490A (xx)
PE (1) PE62796A1 (xx)
TR (1) TR199501599A2 (xx)
WO (1) WO1996019196A1 (xx)

Families Citing this family (45)

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US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
ES2187024T3 (es) * 1997-05-07 2003-05-16 Galen Chemicals Ltd Dispositivo intravaginales de liberacion de farmacos para la adimistracion testosterona y de precursores de testosterona.
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6811549B2 (en) 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US6962908B2 (en) * 2001-12-21 2005-11-08 Warner Chilcott Company Inc. Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
WO2003080019A1 (en) * 2002-03-27 2003-10-02 Galen (Chemicals) Limited Intravaginal reservoir drug delivery devices
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
AU2004233997C1 (en) * 2003-04-29 2014-01-30 Massachusetts Institiute Of Technology Methods and devices for the sustained release of multiple drugs
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
CA2596933A1 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Devices for delivering agents to a vaginal tract
CA2601773A1 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Compositions of unconjugated estrogens and methods for their use
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
CA2625264C (en) 2005-10-13 2015-12-15 Synthes (U.S.A.) Drug-impregnated sleeve for a medical implant
GB0613333D0 (en) * 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) * 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
US20080160065A1 (en) * 2006-07-12 2008-07-03 Janet Anne Halliday Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) * 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
CA2698143C (en) * 2007-06-26 2016-01-19 Warner Chilcott Company, Llc Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs
NZ585449A (en) 2007-12-11 2012-07-27 Massachusetts Inst Technology Implantable drug delivery device and methods for treatment of the bladder and other body vestcles or lumens
JP5908279B2 (ja) * 2008-08-09 2016-04-26 マサチューセッツ インスチテュート オブ テクノロジーＭａｓｓａｃｈｕｓｅｔｔｓ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ 移植可能な薬物送達デバイス並びに男性の尿生殖器及び周囲組織を治療する方法
EP2437684B1 (en) 2009-06-03 2022-06-15 ForSight Vision5, Inc. Anterior segment drug delivery
SG177360A1 (en) 2009-06-26 2012-02-28 Taris Biomedical Inc Implantable drug delivery devices and methods of making the same
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
CA2823783C (en) 2011-01-10 2023-03-21 Taris Biomedical, Inc. Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding
CN103379902B (zh) 2011-02-04 2015-11-25 塔里斯生物医药公司 用于低溶解度药物的控制释放的可植入装置
KR102071083B1 (ko) 2011-09-14 2020-01-29 포사이트 비젼5, 인크. 안내 삽입물 장치 및 방법
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
RU2652063C2 (ru) 2012-10-26 2018-04-24 Форсайт Вижн5, Инк. Офтальмологическая система для замедленного высвобождения лекарственного средства в глазу
BR112015022433B1 (pt) 2013-03-15 2022-06-21 Taris Biomedical Llc Dispositivo de liberação de droga intravesical
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
IL299897B2 (en) 2013-08-19 2024-02-01 Taris Biomedical Llc Devices and methods for administering multiple units of drug
CN104546668B (zh) * 2013-10-23 2019-03-05 国家卫生计生委科学技术研究所 液体硅橡胶为载体的药物缓控释系统的制备及应用
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
CA2944436C (en) * 2014-04-01 2023-08-22 Poly-Med, Inc. Contraceptive and related device
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
US10894150B2 (en) 2015-04-23 2021-01-19 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4291014A (en) * 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
SE8602666D0 (sv) * 1986-06-16 1986-06-16 Leo Ab Intravaginal devices

Also Published As

Publication number Publication date
PE62796A1 (es) 1996-12-28
NO972798D0 (no) 1997-06-17
FI972579A (fi) 1997-06-17
CN1138526C (zh) 2004-02-18
AU692659B2 (en) 1998-06-11
EP0799025A1 (en) 1997-10-08
AU4399196A (en) 1996-07-10
DE69508791T2 (de) 1999-12-02
CA2207622A1 (en) 1996-06-27
AR002010A1 (es) 1998-01-07
ATE178204T1 (de) 1999-04-15
JPH10510825A (ja) 1998-10-20
DE69508791D1 (de) 1999-05-06
TR199501599A2 (tr) 1996-07-21
IL116433A0 (en) 1996-03-31
DK0799025T3 (da) 1999-10-18
FI119414B (fi) 2008-11-14
GR3030614T3 (en) 1999-10-29
NZ298490A (en) 1999-11-29
FI972579A0 (fi) 1997-06-17
NO316707B1 (no) 2004-04-13
CN1170353A (zh) 1998-01-14
EP0799025B1 (en) 1999-03-31
CA2207622C (en) 2006-10-17
WO1996019196A1 (en) 1996-06-27
US5855906A (en) 1999-01-05
NO972798L (no) 1997-08-19
ES2133841T3 (es) 1999-09-16

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