IL116126A0 - Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them - Google Patents

Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Info

Publication number
IL116126A0
IL116126A0 IL11612695A IL11612695A IL116126A0 IL 116126 A0 IL116126 A0 IL 116126A0 IL 11612695 A IL11612695 A IL 11612695A IL 11612695 A IL11612695 A IL 11612695A IL 116126 A0 IL116126 A0 IL 116126A0
Authority
IL
Israel
Prior art keywords
bchl
bacterio
preparation
metallated
recovering
Prior art date
Application number
IL11612695A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL11612695A priority Critical patent/IL116126A0/xx
Publication of IL116126A0 publication Critical patent/IL116126A0/xx
Priority to SI9630757T priority patent/SI0863903T1/sl
Priority to DK96938445T priority patent/DK0863903T3/da
Priority to JP9519568A priority patent/JP2000500763A/ja
Priority to RU98111943/04A priority patent/RU2193038C2/ru
Priority to EP96938445A priority patent/EP0863903B1/en
Priority to CN96199752A priority patent/CN1085211C/zh
Priority to IL12450296A priority patent/IL124502A0/xx
Priority to BR9611452A priority patent/BR9611452A/pt
Priority to AU75857/96A priority patent/AU718961B2/en
Priority to DE69637149T priority patent/DE69637149T2/de
Priority to CA 2237056 priority patent/CA2237056C/en
Priority to US09/077,208 priority patent/US6333319B1/en
Priority to PCT/IL1996/000161 priority patent/WO1997019081A1/en
Priority to HU9903582A priority patent/HU223379B1/hu
Priority to PT96938445T priority patent/PT863903E/pt
Priority to ES96938445T priority patent/ES2288757T3/es
Priority to PL96326745A priority patent/PL188811B1/pl
Priority to AT96938445T priority patent/ATE365741T1/de
Priority to NZ501912A priority patent/NZ501912A/en
Priority to NO19982348A priority patent/NO323478B1/no
Priority to MX9804143A priority patent/MX9804143A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11612695A 1995-11-24 1995-11-24 Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them IL116126A0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
IL11612695A IL116126A0 (en) 1995-11-24 1995-11-24 Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them
NZ501912A NZ501912A (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use for killing viruses and microorganisms
DE69637149T DE69637149T2 (de) 1995-11-24 1996-11-24 Synthetische metall-substituierte bacteriochloropyllderivate und ihre verwendung
US09/077,208 US6333319B1 (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
JP9519568A JP2000500763A (ja) 1995-11-24 1996-11-24 合成の金属置換されたバクテリオクロロフィル誘導体およびその使用
RU98111943/04A RU2193038C2 (ru) 1995-11-24 1996-11-24 Способ получения металлсодержащих производных бактериохлорофилла, новые металлированные производные бактериохлорофилла, фармацевтическая композиция
EP96938445A EP0863903B1 (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
CN96199752A CN1085211C (zh) 1995-11-24 1996-11-24 合成金属取代的细菌叶绿素衍生物及其应用
IL12450296A IL124502A0 (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
BR9611452A BR9611452A (pt) 1995-11-24 1996-11-24 Derivados sinteticos de bacterioclorofila substituida c/metal e o uso dos mesmos
AU75857/96A AU718961B2 (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
SI9630757T SI0863903T1 (sl) 1995-11-24 1996-11-24 Sintetični, s kovino substituirani bakterioklorofilni derivati in njihova uporaba
CA 2237056 CA2237056C (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
DK96938445T DK0863903T3 (da) 1995-11-24 1996-11-24 Syntetiske metalsubstituerede bacteriochlorophylderivat og anvendelse deraf
PCT/IL1996/000161 WO1997019081A1 (en) 1995-11-24 1996-11-24 Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
HU9903582A HU223379B1 (hu) 1995-11-24 1996-11-24 Eljárás szintetikus fém-szubsztituált bakterio-klorofill-származékok előállítására, a vegyületek alkalmazása és a vegyületeket tartalmazó gyógyszerkészítmények
PT96938445T PT863903E (pt) 1995-11-24 1996-11-24 Derivados sintéticos de bacterioclorofila substituídos por metal e a sua utilização
ES96938445T ES2288757T3 (es) 1995-11-24 1996-11-24 Derivados sinteticos de bacterioclorofila sustituidos con metales y uso de los mismos.
PL96326745A PL188811B1 (pl) 1995-11-24 1996-11-24 Metalowane syntetyczne pochodne bakteriochlorofilu, sposób ich wytwarzania, kompozycja farmaceutyczna i jej zastosowanie
AT96938445T ATE365741T1 (de) 1995-11-24 1996-11-24 Synthetische metall-substituierte bacteriochloropyllderivate und ihre verwendung
NO19982348A NO323478B1 (no) 1995-11-24 1998-05-22 Syntetiske metall-substituerte bakterioklorofyllderivater samt anvendelse derav
MX9804143A MX9804143A (es) 1995-11-24 1998-05-25 Derivados sinteticos de bacterioclorofila substituidos con metal, y uso de los mismos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11612695A IL116126A0 (en) 1995-11-24 1995-11-24 Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Publications (1)

Publication Number Publication Date
IL116126A0 true IL116126A0 (en) 1996-01-31

Family

ID=11068225

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11612695A IL116126A0 (en) 1995-11-24 1995-11-24 Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Country Status (18)

Country Link
US (1) US6333319B1 (ru)
EP (1) EP0863903B1 (ru)
JP (1) JP2000500763A (ru)
CN (1) CN1085211C (ru)
AT (1) ATE365741T1 (ru)
AU (1) AU718961B2 (ru)
BR (1) BR9611452A (ru)
DE (1) DE69637149T2 (ru)
DK (1) DK0863903T3 (ru)
ES (1) ES2288757T3 (ru)
HU (1) HU223379B1 (ru)
IL (1) IL116126A0 (ru)
MX (1) MX9804143A (ru)
NO (1) NO323478B1 (ru)
PL (1) PL188811B1 (ru)
PT (1) PT863903E (ru)
RU (1) RU2193038C2 (ru)
WO (1) WO1997019081A1 (ru)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413436B1 (en) * 1999-01-27 2002-07-02 Semitool, Inc. Selective treatment of the surface of a microelectronic workpiece
EP1137411B1 (en) * 1998-12-09 2006-12-06 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Palladium-substituted bacteriochlorophyll derivatives and use thereof
US7045117B2 (en) * 1999-12-01 2006-05-16 Yeda Research And Development Co. Ltd. Method for tumor diagnosis comprising administering of palladium-substituted bacteriochlorophyll derivatives
IL133253A0 (en) * 1999-12-01 2001-04-30 Yeda Res & Dev Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
WO2002013820A1 (en) * 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Photosensitizing ointment
RU2183956C1 (ru) * 2001-03-30 2002-06-27 Общество с ограниченной ответственностью "РАДА-ФАРМА" Фотосенсибилизатор и способ его получения
EP1277470A1 (fr) * 2001-07-17 2003-01-22 Steba Biotech N.V. Formulation galénique injectable pour utilisation dans un diagnostic ou une thérapie photodynamique et son procédé de préparation
IL148921A0 (en) * 2002-03-26 2002-09-12 Peptor Ltd Photo active backbone cyclized somatostatin analogs for optical imaging and photodynamic therapy
AU2003230164B2 (en) 2002-05-08 2008-05-01 Yeda Research And Development Co. Ltd. Sensitized online BOLD-MRI imaging method
CN2595398Y (zh) 2002-09-25 2003-12-31 王健 动态加静态磁脉冲理疗仪
IL152900A0 (en) 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
EP2322173B1 (en) * 2004-06-07 2016-08-10 Yeda Research And Development Co., Ltd. Cationic bacteriochlorophyll derivatives and uses thereof
CA2568744A1 (en) 2004-06-09 2005-12-22 Qlt Inc. Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
WO2008018063A2 (en) * 2006-08-07 2008-02-14 Kodesh S.A Tetraarylporphine derivatives and uses thereof
DK2061512T3 (da) * 2006-08-23 2020-01-20 Yeda Res & Dev Konjugater af rgd-peptider og (bakterie)chlorophylfotosensibilisatorer samt anvendelser deraf
EP2155691B1 (en) * 2007-02-23 2016-01-13 Yeda Research and Development Co. Ltd. Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
US20110040170A1 (en) * 2008-01-28 2011-02-17 Yeda Research And Development Co., Ltd. Endoscopic imaging photodynamic therapy system and methods of use
AU2009219682B2 (en) 2008-02-27 2015-06-18 Yeda Research & Development Co. Ltd RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors
RU2415868C1 (ru) 2009-09-10 2011-04-10 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Производные гемина, обладающие антимикробной активностью, или их фармацевтически приемлемые соли, способ получения, фармкомпозиция и применение
CN102584837A (zh) * 2012-01-18 2012-07-18 河北联合大学 天然叶绿素铁铬盐及制备方法
CN103405769A (zh) * 2013-03-07 2013-11-27 北京亿仁赛博医疗科技研发中心有限公司 光敏剂在制备治疗疾病的病毒灭活药物中的应用
CA2905109C (en) 2013-03-11 2021-03-16 Tookad Ip Sarl Method for producing bacteriochlorophyll a
CN109679110B (zh) * 2018-12-25 2020-10-09 北京科技大学 一种基于菌绿素的纳米金属-有机框架光敏剂及制备方法
CN114005684B (zh) * 2021-11-05 2023-05-05 吉林大学 不饱和叶绿素的电化学聚合薄膜及其在超级电容器上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121876A1 (de) 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
IL102645A (en) 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
US5591847A (en) * 1994-05-23 1997-01-07 Health Research, Inc. Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages

Also Published As

Publication number Publication date
ATE365741T1 (de) 2007-07-15
CN1207741A (zh) 1999-02-10
US6333319B1 (en) 2001-12-25
NO323478B1 (no) 2007-05-21
DE69637149T2 (de) 2008-02-28
BR9611452A (pt) 1999-02-17
NO982348L (no) 1998-07-23
JP2000500763A (ja) 2000-01-25
CN1085211C (zh) 2002-05-22
ES2288757T3 (es) 2008-01-16
PL326745A1 (en) 1998-10-26
DK0863903T3 (da) 2007-09-24
AU718961B2 (en) 2000-05-04
EP0863903B1 (en) 2007-06-27
RU2193038C2 (ru) 2002-11-20
MX9804143A (es) 1998-09-30
NO982348D0 (no) 1998-05-22
AU7585796A (en) 1997-06-11
DE69637149D1 (de) 2007-08-09
HU223379B1 (hu) 2004-06-28
EP0863903A1 (en) 1998-09-16
PT863903E (pt) 2007-09-07
WO1997019081A1 (en) 1997-05-29
PL188811B1 (pl) 2005-04-29
HUP9903582A2 (hu) 2000-02-28
HUP9903582A3 (en) 2002-02-28

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