IL116126A0 - Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them - Google Patents
Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising themInfo
- Publication number
- IL116126A0 IL116126A0 IL11612695A IL11612695A IL116126A0 IL 116126 A0 IL116126 A0 IL 116126A0 IL 11612695 A IL11612695 A IL 11612695A IL 11612695 A IL11612695 A IL 11612695A IL 116126 A0 IL116126 A0 IL 116126A0
- Authority
- IL
- Israel
- Prior art keywords
- bchl
- bacterio
- preparation
- metallated
- recovering
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052751 metal Inorganic materials 0.000 abstract 5
- 239000002184 metal Substances 0.000 abstract 5
- 150000002739 metals Chemical class 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- DSJXIQQMORJERS-AGGZHOMASA-M bacteriochlorophyll a Chemical class C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC([C@H](CC)[C@H]3C)=[N+]4C3=CC3=C(C(C)=O)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 DSJXIQQMORJERS-AGGZHOMASA-M 0.000 abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- POILWHVDKZOXJZ-ARJAWSKDSA-M (z)-4-oxopent-2-en-2-olate Chemical compound C\C([O-])=C\C(C)=O POILWHVDKZOXJZ-ARJAWSKDSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 abstract 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- KWOZSBGNAHVCKG-WFDCHTCOSA-N bacteriopheophytin a Chemical class N1C(C=C2[C@H]([C@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=N2)C2=C3NC(=C4)C(C)=C3C(=O)[C@@H]2C(=O)OC)C)=C(C)C(C(C)=O)=C1C=C1[C@H](C)[C@@H](CC)C4=N1 KWOZSBGNAHVCKG-WFDCHTCOSA-N 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 229910052804 chromium Inorganic materials 0.000 abstract 1
- 239000011651 chromium Substances 0.000 abstract 1
- 229910017052 cobalt Inorganic materials 0.000 abstract 1
- 239000010941 cobalt Substances 0.000 abstract 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 229910052748 manganese Inorganic materials 0.000 abstract 1
- 239000011572 manganese Substances 0.000 abstract 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL11612695A IL116126A0 (en) | 1995-11-24 | 1995-11-24 | Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them |
NZ501912A NZ501912A (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use for killing viruses and microorganisms |
DE69637149T DE69637149T2 (de) | 1995-11-24 | 1996-11-24 | Synthetische metall-substituierte bacteriochloropyllderivate und ihre verwendung |
US09/077,208 US6333319B1 (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
JP9519568A JP2000500763A (ja) | 1995-11-24 | 1996-11-24 | 合成の金属置換されたバクテリオクロロフィル誘導体およびその使用 |
RU98111943/04A RU2193038C2 (ru) | 1995-11-24 | 1996-11-24 | Способ получения металлсодержащих производных бактериохлорофилла, новые металлированные производные бактериохлорофилла, фармацевтическая композиция |
EP96938445A EP0863903B1 (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
CN96199752A CN1085211C (zh) | 1995-11-24 | 1996-11-24 | 合成金属取代的细菌叶绿素衍生物及其应用 |
IL12450296A IL124502A0 (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
BR9611452A BR9611452A (pt) | 1995-11-24 | 1996-11-24 | Derivados sinteticos de bacterioclorofila substituida c/metal e o uso dos mesmos |
AU75857/96A AU718961B2 (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
SI9630757T SI0863903T1 (sl) | 1995-11-24 | 1996-11-24 | Sintetični, s kovino substituirani bakterioklorofilni derivati in njihova uporaba |
CA 2237056 CA2237056C (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
DK96938445T DK0863903T3 (da) | 1995-11-24 | 1996-11-24 | Syntetiske metalsubstituerede bacteriochlorophylderivat og anvendelse deraf |
PCT/IL1996/000161 WO1997019081A1 (en) | 1995-11-24 | 1996-11-24 | Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof |
HU9903582A HU223379B1 (hu) | 1995-11-24 | 1996-11-24 | Eljárás szintetikus fém-szubsztituált bakterio-klorofill-származékok előállítására, a vegyületek alkalmazása és a vegyületeket tartalmazó gyógyszerkészítmények |
PT96938445T PT863903E (pt) | 1995-11-24 | 1996-11-24 | Derivados sintéticos de bacterioclorofila substituídos por metal e a sua utilização |
ES96938445T ES2288757T3 (es) | 1995-11-24 | 1996-11-24 | Derivados sinteticos de bacterioclorofila sustituidos con metales y uso de los mismos. |
PL96326745A PL188811B1 (pl) | 1995-11-24 | 1996-11-24 | Metalowane syntetyczne pochodne bakteriochlorofilu, sposób ich wytwarzania, kompozycja farmaceutyczna i jej zastosowanie |
AT96938445T ATE365741T1 (de) | 1995-11-24 | 1996-11-24 | Synthetische metall-substituierte bacteriochloropyllderivate und ihre verwendung |
NO19982348A NO323478B1 (no) | 1995-11-24 | 1998-05-22 | Syntetiske metall-substituerte bakterioklorofyllderivater samt anvendelse derav |
MX9804143A MX9804143A (es) | 1995-11-24 | 1998-05-25 | Derivados sinteticos de bacterioclorofila substituidos con metal, y uso de los mismos. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL11612695A IL116126A0 (en) | 1995-11-24 | 1995-11-24 | Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them |
Publications (1)
Publication Number | Publication Date |
---|---|
IL116126A0 true IL116126A0 (en) | 1996-01-31 |
Family
ID=11068225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11612695A IL116126A0 (en) | 1995-11-24 | 1995-11-24 | Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them |
Country Status (18)
Country | Link |
---|---|
US (1) | US6333319B1 (ru) |
EP (1) | EP0863903B1 (ru) |
JP (1) | JP2000500763A (ru) |
CN (1) | CN1085211C (ru) |
AT (1) | ATE365741T1 (ru) |
AU (1) | AU718961B2 (ru) |
BR (1) | BR9611452A (ru) |
DE (1) | DE69637149T2 (ru) |
DK (1) | DK0863903T3 (ru) |
ES (1) | ES2288757T3 (ru) |
HU (1) | HU223379B1 (ru) |
IL (1) | IL116126A0 (ru) |
MX (1) | MX9804143A (ru) |
NO (1) | NO323478B1 (ru) |
PL (1) | PL188811B1 (ru) |
PT (1) | PT863903E (ru) |
RU (1) | RU2193038C2 (ru) |
WO (1) | WO1997019081A1 (ru) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6413436B1 (en) * | 1999-01-27 | 2002-07-02 | Semitool, Inc. | Selective treatment of the surface of a microelectronic workpiece |
EP1137411B1 (en) * | 1998-12-09 | 2006-12-06 | YEDA RESEARCH AND DEVELOPMENT Co. LTD. | Palladium-substituted bacteriochlorophyll derivatives and use thereof |
US7045117B2 (en) * | 1999-12-01 | 2006-05-16 | Yeda Research And Development Co. Ltd. | Method for tumor diagnosis comprising administering of palladium-substituted bacteriochlorophyll derivatives |
IL133253A0 (en) * | 1999-12-01 | 2001-04-30 | Yeda Res & Dev | Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them |
WO2002013820A1 (en) * | 2000-08-11 | 2002-02-21 | Ceramoptec Industries, Inc. | Photosensitizing ointment |
RU2183956C1 (ru) * | 2001-03-30 | 2002-06-27 | Общество с ограниченной ответственностью "РАДА-ФАРМА" | Фотосенсибилизатор и способ его получения |
EP1277470A1 (fr) * | 2001-07-17 | 2003-01-22 | Steba Biotech N.V. | Formulation galénique injectable pour utilisation dans un diagnostic ou une thérapie photodynamique et son procédé de préparation |
IL148921A0 (en) * | 2002-03-26 | 2002-09-12 | Peptor Ltd | Photo active backbone cyclized somatostatin analogs for optical imaging and photodynamic therapy |
AU2003230164B2 (en) | 2002-05-08 | 2008-05-01 | Yeda Research And Development Co. Ltd. | Sensitized online BOLD-MRI imaging method |
CN2595398Y (zh) | 2002-09-25 | 2003-12-31 | 王健 | 动态加静态磁脉冲理疗仪 |
IL152900A0 (en) | 2002-11-17 | 2003-06-24 | Yeda Res & Dev | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
CA2437638A1 (en) | 2003-08-20 | 2005-02-20 | John Robert North | Photodynamic therapy |
CA2457214A1 (en) | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
EP2322173B1 (en) * | 2004-06-07 | 2016-08-10 | Yeda Research And Development Co., Ltd. | Cationic bacteriochlorophyll derivatives and uses thereof |
CA2568744A1 (en) | 2004-06-09 | 2005-12-22 | Qlt Inc. | Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins |
WO2008018063A2 (en) * | 2006-08-07 | 2008-02-14 | Kodesh S.A | Tetraarylporphine derivatives and uses thereof |
DK2061512T3 (da) * | 2006-08-23 | 2020-01-20 | Yeda Res & Dev | Konjugater af rgd-peptider og (bakterie)chlorophylfotosensibilisatorer samt anvendelser deraf |
EP2155691B1 (en) * | 2007-02-23 | 2016-01-13 | Yeda Research and Development Co. Ltd. | Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins |
US20090036952A1 (en) | 2007-07-30 | 2009-02-05 | National Yang-Ming University | Induction driven light module and use thereof |
US20110040170A1 (en) * | 2008-01-28 | 2011-02-17 | Yeda Research And Development Co., Ltd. | Endoscopic imaging photodynamic therapy system and methods of use |
AU2009219682B2 (en) | 2008-02-27 | 2015-06-18 | Yeda Research & Development Co. Ltd | RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors |
RU2415868C1 (ru) | 2009-09-10 | 2011-04-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные гемина, обладающие антимикробной активностью, или их фармацевтически приемлемые соли, способ получения, фармкомпозиция и применение |
CN102584837A (zh) * | 2012-01-18 | 2012-07-18 | 河北联合大学 | 天然叶绿素铁铬盐及制备方法 |
CN103405769A (zh) * | 2013-03-07 | 2013-11-27 | 北京亿仁赛博医疗科技研发中心有限公司 | 光敏剂在制备治疗疾病的病毒灭活药物中的应用 |
CA2905109C (en) | 2013-03-11 | 2021-03-16 | Tookad Ip Sarl | Method for producing bacteriochlorophyll a |
CN109679110B (zh) * | 2018-12-25 | 2020-10-09 | 北京科技大学 | 一种基于菌绿素的纳米金属-有机框架光敏剂及制备方法 |
CN114005684B (zh) * | 2021-11-05 | 2023-05-05 | 吉林大学 | 不饱和叶绿素的电化学聚合薄膜及其在超级电容器上的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5171741A (en) * | 1989-04-21 | 1992-12-15 | Health Research, Inc. | Bacteriochlorophyll-a derivatives useful in photodynamic therapy |
DE4121876A1 (de) | 1991-07-02 | 1993-01-14 | Scheer Hugo | Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung |
IL102645A (en) | 1992-07-26 | 1998-02-22 | Yeda Res & Dev | Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them |
US5591847A (en) * | 1994-05-23 | 1997-01-07 | Health Research, Inc. | Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages |
-
1995
- 1995-11-24 IL IL11612695A patent/IL116126A0/xx unknown
-
1996
- 1996-11-24 US US09/077,208 patent/US6333319B1/en not_active Expired - Fee Related
- 1996-11-24 ES ES96938445T patent/ES2288757T3/es not_active Expired - Lifetime
- 1996-11-24 BR BR9611452A patent/BR9611452A/pt not_active Application Discontinuation
- 1996-11-24 CN CN96199752A patent/CN1085211C/zh not_active Expired - Fee Related
- 1996-11-24 DE DE69637149T patent/DE69637149T2/de not_active Expired - Fee Related
- 1996-11-24 EP EP96938445A patent/EP0863903B1/en not_active Expired - Lifetime
- 1996-11-24 PL PL96326745A patent/PL188811B1/pl not_active IP Right Cessation
- 1996-11-24 JP JP9519568A patent/JP2000500763A/ja not_active Ceased
- 1996-11-24 DK DK96938445T patent/DK0863903T3/da active
- 1996-11-24 HU HU9903582A patent/HU223379B1/hu not_active IP Right Cessation
- 1996-11-24 WO PCT/IL1996/000161 patent/WO1997019081A1/en active IP Right Grant
- 1996-11-24 AU AU75857/96A patent/AU718961B2/en not_active Ceased
- 1996-11-24 PT PT96938445T patent/PT863903E/pt unknown
- 1996-11-24 AT AT96938445T patent/ATE365741T1/de not_active IP Right Cessation
- 1996-11-24 RU RU98111943/04A patent/RU2193038C2/ru not_active IP Right Cessation
-
1998
- 1998-05-22 NO NO19982348A patent/NO323478B1/no unknown
- 1998-05-25 MX MX9804143A patent/MX9804143A/es unknown
Also Published As
Publication number | Publication date |
---|---|
ATE365741T1 (de) | 2007-07-15 |
CN1207741A (zh) | 1999-02-10 |
US6333319B1 (en) | 2001-12-25 |
NO323478B1 (no) | 2007-05-21 |
DE69637149T2 (de) | 2008-02-28 |
BR9611452A (pt) | 1999-02-17 |
NO982348L (no) | 1998-07-23 |
JP2000500763A (ja) | 2000-01-25 |
CN1085211C (zh) | 2002-05-22 |
ES2288757T3 (es) | 2008-01-16 |
PL326745A1 (en) | 1998-10-26 |
DK0863903T3 (da) | 2007-09-24 |
AU718961B2 (en) | 2000-05-04 |
EP0863903B1 (en) | 2007-06-27 |
RU2193038C2 (ru) | 2002-11-20 |
MX9804143A (es) | 1998-09-30 |
NO982348D0 (no) | 1998-05-22 |
AU7585796A (en) | 1997-06-11 |
DE69637149D1 (de) | 2007-08-09 |
HU223379B1 (hu) | 2004-06-28 |
EP0863903A1 (en) | 1998-09-16 |
PT863903E (pt) | 2007-09-07 |
WO1997019081A1 (en) | 1997-05-29 |
PL188811B1 (pl) | 2005-04-29 |
HUP9903582A2 (hu) | 2000-02-28 |
HUP9903582A3 (en) | 2002-02-28 |
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