IL115074A - New salt of) S1, R4 (cis-] 2-amino-6-) cyclopropylamino (H9 purine 9 ile [2-cyclopentane-1-methanol and its solvates, their preparation and pharmaceutical preparations containing or - Google Patents

New salt of) S1, R4 (cis-] 2-amino-6-) cyclopropylamino (H9 purine 9 ile [2-cyclopentane-1-methanol and its solvates, their preparation and pharmaceutical preparations containing or

Info

Publication number
IL115074A
IL115074A IL11507495A IL11507495A IL115074A IL 115074 A IL115074 A IL 115074A IL 11507495 A IL11507495 A IL 11507495A IL 11507495 A IL11507495 A IL 11507495A IL 115074 A IL115074 A IL 115074A
Authority
IL
Israel
Prior art keywords
compound
purin
methanol
cyclopentene
cyclopropylamino
Prior art date
Application number
IL11507495A
Other languages
English (en)
Hebrew (he)
Other versions
IL115074A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL115074A0 publication Critical patent/IL115074A0/xx
Publication of IL115074A publication Critical patent/IL115074A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Seasonings (AREA)
IL11507495A 1994-08-26 1995-08-25 New salt of) S1, R4 (cis-] 2-amino-6-) cyclopropylamino (H9 purine 9 ile [2-cyclopentane-1-methanol and its solvates, their preparation and pharmaceutical preparations containing or IL115074A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417249A GB9417249D0 (en) 1994-08-26 1994-08-26 A novel salt

Publications (2)

Publication Number Publication Date
IL115074A0 IL115074A0 (en) 1995-12-08
IL115074A true IL115074A (en) 1998-10-30

Family

ID=10760434

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11507495A IL115074A (en) 1994-08-26 1995-08-25 New salt of) S1, R4 (cis-] 2-amino-6-) cyclopropylamino (H9 purine 9 ile [2-cyclopentane-1-methanol and its solvates, their preparation and pharmaceutical preparations containing or

Country Status (23)

Country Link
EP (1) EP0777669B1 (fi)
JP (1) JPH10505593A (fi)
KR (1) KR100376240B1 (fi)
CN (1) CN1051550C (fi)
AT (1) ATE220067T1 (fi)
AU (1) AU702618B2 (fi)
BR (1) BR9508629A (fi)
CA (1) CA2198010C (fi)
DE (1) DE69527294T2 (fi)
DK (1) DK0777669T3 (fi)
ES (1) ES2179110T3 (fi)
FI (1) FI120403B (fi)
GB (1) GB9417249D0 (fi)
HU (1) HU221302B1 (fi)
IL (1) IL115074A (fi)
MX (1) MX9701273A (fi)
NO (1) NO315200B1 (fi)
NZ (1) NZ291862A (fi)
PT (1) PT777669E (fi)
RU (1) RU2145324C1 (fi)
SI (1) SI0777669T1 (fi)
WO (1) WO1996006844A1 (fi)
ZA (1) ZA957166B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY115461A (en) 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
GB9709945D0 (en) 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
AU7912398A (en) * 1997-05-17 1998-12-11 Glaxo Group Limited Antiviral combinations containing the carbocyclic nucleoside 1592u89
NZ500868A (en) * 1997-05-17 2001-08-31 Glaxo Group Ltd Antiviral combinations comprising 1592U89 and HIV protease inhibitors
SK284595B6 (sk) * 1997-11-27 2005-07-01 Lonza Ag Spôsob výroby (1S,4R)-4-(2-amino-6-chlór-9H-purín-9-yl)-2- cyklopentén-1-metanolu alebo jeho solí
GB9802472D0 (en) * 1998-02-06 1998-04-01 Glaxo Group Ltd Pharmaceutical compositions
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
AU2002355739A1 (en) 2001-07-30 2003-02-17 University Of Southern California Preparation and use of alpha-keto phosphonates
JP4542550B2 (ja) * 2003-10-27 2010-09-15 メルク・シャープ・エンド・ドーム・コーポレイション Ｃｃｒ−２アンタゴニスト塩
EP2305680A3 (en) * 2009-09-30 2011-05-18 Aurobindo Pharma Limited Novel salts of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
EP2697238B1 (en) 2011-04-08 2019-03-20 Laurus Labs Limited Solid forms of antiretroviral compounds, process for the preparation and their pharmaceutical composition thereof
US9457028B2 (en) 2013-02-27 2016-10-04 Kyoto University Pharmaceutical composition for use in prevention or treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3025492A1 (de) * 1980-07-04 1982-02-04 Siemens AG, 1000 Berlin und 8000 München Filterelement fuer die optische nachrichtentechnik
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
IL104283A (en) * 1992-12-30 1996-12-05 Agis Ind 1983 Ltd Non-emulsion antiviral topical pharmaceutical composition comprising acyclovir an aqueous gel agent and an alkali oleate

Also Published As

Publication number Publication date
ZA957166B (en) 1997-02-25
IL115074A0 (en) 1995-12-08
SI0777669T1 (en) 2002-12-31
GB9417249D0 (en) 1994-10-19
PT777669E (pt) 2002-11-29
CA2198010C (en) 2006-05-02
CA2198010A1 (en) 1996-03-07
DE69527294D1 (en) 2002-08-08
RU2145324C1 (ru) 2000-02-10
BR9508629A (pt) 1997-11-25
DK0777669T3 (da) 2002-10-28
AU702618B2 (en) 1999-02-25
DE69527294T2 (de) 2003-02-13
CN1051550C (zh) 2000-04-19
HU221302B1 (en) 2002-09-28
NO970847L (no) 1997-02-25
CN1156456A (zh) 1997-08-06
NO315200B1 (no) 2003-07-28
EP0777669A1 (en) 1997-06-11
AU3350995A (en) 1996-03-22
NO970847D0 (no) 1997-02-25
FI970786A0 (fi) 1997-02-25
ATE220067T1 (de) 2002-07-15
FI120403B (fi) 2009-10-15
JPH10505593A (ja) 1998-06-02
KR970705563A (ko) 1997-10-09
FI970786A (fi) 1997-02-25
NZ291862A (en) 1998-02-26
ES2179110T3 (es) 2003-01-16
HUT77222A (hu) 1998-03-02
WO1996006844A1 (en) 1996-03-07
EP0777669B1 (en) 2002-07-03
MX9701273A (es) 1997-05-31
KR100376240B1 (ko) 2003-06-11

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