HUT77222A - Antivirális hatású (1S,4R)-cisz-4-[2-amino-6-(ciklopropil-amino)-9H-purin-9-il]-2-ciklopentén-1-metanol borostyánkősavsó, eljárás előállítására és az azt tartalmazó gyógyszerkészítmény - Google Patents

Antivirális hatású (1S,4R)-cisz-4-[2-amino-6-(ciklopropil-amino)-9H-purin-9-il]-2-ciklopentén-1-metanol borostyánkősavsó, eljárás előállítására és az azt tartalmazó gyógyszerkészítmény

Info

Publication number
HUT77222A
HUT77222A HU9701756A HU9701756A HUT77222A HU T77222 A HUT77222 A HU T77222A HU 9701756 A HU9701756 A HU 9701756A HU 9701756 A HU9701756 A HU 9701756A HU T77222 A HUT77222 A HU T77222A
Authority
HU
Hungary
Prior art keywords
purin
cyclopropylamino
cyclopentene
amino
production
Prior art date
Application number
HU9701756A
Other languages
English (en)
Other versions
HU221302B1 (en
Inventor
Susan Mary Daluge
Jeffrey Douglas Wilson
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of HUT77222A publication Critical patent/HUT77222A/hu
Publication of HU221302B1 publication Critical patent/HU221302B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Seasonings (AREA)
HU9701756A 1994-08-26 1995-08-25 4-(2-amino-6-(cyclopropylamino)-9h-purin-9-yl)-2-cyclopentene-1-methanol succinate as antiviral agent, process for its production and pharmaceutical composition containing the same HU221302B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9417249A GB9417249D0 (en) 1994-08-26 1994-08-26 A novel salt
PCT/GB1995/002014 WO1996006844A1 (en) 1994-08-26 1995-08-25 4-(2-amino-6-(cyclopropylamino)-9h-purin-9-yl)-2-cyclopentene-1-methanol succinate as antiviral agent

Publications (2)

Publication Number Publication Date
HUT77222A true HUT77222A (hu) 1998-03-02
HU221302B1 HU221302B1 (en) 2002-09-28

Family

ID=10760434

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9701756A HU221302B1 (en) 1994-08-26 1995-08-25 4-(2-amino-6-(cyclopropylamino)-9h-purin-9-yl)-2-cyclopentene-1-methanol succinate as antiviral agent, process for its production and pharmaceutical composition containing the same

Country Status (23)

Country Link
EP (1) EP0777669B1 (hu)
JP (1) JPH10505593A (hu)
KR (1) KR100376240B1 (hu)
CN (1) CN1051550C (hu)
AT (1) ATE220067T1 (hu)
AU (1) AU702618B2 (hu)
BR (1) BR9508629A (hu)
CA (1) CA2198010C (hu)
DE (1) DE69527294T2 (hu)
DK (1) DK0777669T3 (hu)
ES (1) ES2179110T3 (hu)
FI (1) FI120403B (hu)
GB (1) GB9417249D0 (hu)
HU (1) HU221302B1 (hu)
IL (1) IL115074A (hu)
MX (1) MX9701273A (hu)
NO (1) NO315200B1 (hu)
NZ (1) NZ291862A (hu)
PT (1) PT777669E (hu)
RU (1) RU2145324C1 (hu)
SI (1) SI0777669T1 (hu)
WO (1) WO1996006844A1 (hu)
ZA (1) ZA957166B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY115461A (en) 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
JP2001525840A (ja) * 1997-05-17 2001-12-11 グラクソ、グループ、リミテッド 炭素環式ヌクレオシド１５９２ｕ８９を含有する抗ウイルス的組合せ
AU7912398A (en) * 1997-05-17 1998-12-11 Glaxo Group Limited Antiviral combinations containing the carbocyclic nucleoside 1592u89
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
SK284594B6 (sk) * 1997-11-27 2005-07-01 Lonza Ag Spôsob výroby derivátov aminoalkoholov a ich soli
GB9802472D0 (en) 1998-02-06 1998-04-01 Glaxo Group Ltd Pharmaceutical compositions
GB9903091D0 (en) 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
US7462733B2 (en) 2001-07-30 2008-12-09 University Of Southern California Preparation and use of α-keto phosphonates
AU2004287416C1 (en) * 2003-10-27 2010-09-09 Merck Sharp & Dohme Corp. CCR-2 antagonist salt
EP2305680A3 (en) * 2009-09-30 2011-05-18 Aurobindo Pharma Limited Novel salts of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
CN103282369A (zh) 2011-04-08 2013-09-04 劳乐斯实验室私营有限公司 抗逆转录病毒化合物与抗氧化酸的固体形式、其制备方法以及其药物组合物
WO2014133085A1 (ja) 2013-02-27 2014-09-04 国立大学法人京都大学 がんの予防または治療用医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3025492A1 (de) * 1980-07-04 1982-02-04 Siemens AG, 1000 Berlin und 8000 München Filterelement fuer die optische nachrichtentechnik
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
IL104283A (en) * 1992-12-30 1996-12-05 Agis Ind 1983 Ltd Non-emulsion antiviral topical pharmaceutical composition comprising acyclovir an aqueous gel agent and an alkali oleate

Also Published As

Publication number Publication date
ZA957166B (en) 1997-02-25
NO315200B1 (no) 2003-07-28
KR100376240B1 (ko) 2003-06-11
JPH10505593A (ja) 1998-06-02
NZ291862A (en) 1998-02-26
CN1156456A (zh) 1997-08-06
BR9508629A (pt) 1997-11-25
EP0777669B1 (en) 2002-07-03
CA2198010C (en) 2006-05-02
ES2179110T3 (es) 2003-01-16
MX9701273A (es) 1997-05-31
CN1051550C (zh) 2000-04-19
NO970847D0 (no) 1997-02-25
HU221302B1 (en) 2002-09-28
KR970705563A (ko) 1997-10-09
FI120403B (fi) 2009-10-15
CA2198010A1 (en) 1996-03-07
NO970847L (no) 1997-02-25
FI970786A0 (fi) 1997-02-25
DE69527294T2 (de) 2003-02-13
EP0777669A1 (en) 1997-06-11
IL115074A0 (en) 1995-12-08
WO1996006844A1 (en) 1996-03-07
IL115074A (en) 1998-10-30
DK0777669T3 (da) 2002-10-28
AU3350995A (en) 1996-03-22
ATE220067T1 (de) 2002-07-15
FI970786A (fi) 1997-02-25
AU702618B2 (en) 1999-02-25
DE69527294D1 (en) 2002-08-08
RU2145324C1 (ru) 2000-02-10
SI0777669T1 (en) 2002-12-31
GB9417249D0 (en) 1994-10-19
PT777669E (pt) 2002-11-29

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