IL113430A - In vivo gene expression system - Google Patents
In vivo gene expression systemInfo
- Publication number
- IL113430A IL113430A IL11343095A IL11343095A IL113430A IL 113430 A IL113430 A IL 113430A IL 11343095 A IL11343095 A IL 11343095A IL 11343095 A IL11343095 A IL 11343095A IL 113430 A IL113430 A IL 113430A
- Authority
- IL
- Israel
- Prior art keywords
- pct
- target
- altering
- inhibiting
- sec
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 4
- 238000001727 in vivo Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000994 Catalytic RNA Proteins 0.000 abstract 1
- 102000053642 Catalytic RNA Human genes 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108091092562 ribozyme Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPM5169A AUPM516994A0 (en) | 1994-04-20 | 1994-04-20 | An in vivo gene expression system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL113430A0 IL113430A0 (en) | 1995-07-31 |
| IL113430A true IL113430A (en) | 1999-07-14 |
Family
ID=3779748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11343095A IL113430A (en) | 1994-04-20 | 1995-04-20 | In vivo gene expression system |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5932435A (fr) |
| EP (1) | EP0756634B1 (fr) |
| JP (1) | JPH09511911A (fr) |
| AT (1) | ATE222959T1 (fr) |
| AU (1) | AUPM516994A0 (fr) |
| CA (1) | CA2185550A1 (fr) |
| DE (1) | DE69527951T2 (fr) |
| FI (1) | FI964172A0 (fr) |
| IL (1) | IL113430A (fr) |
| NO (1) | NO964427D0 (fr) |
| WO (1) | WO1995029254A1 (fr) |
| ZA (1) | ZA953208B (fr) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002515730A (ja) * | 1995-10-16 | 2002-05-28 | カイロン コーポレイション | 遺伝子発現を変調する因子のスクリーニング方法 |
| US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
| CA2277414A1 (fr) | 1997-11-07 | 1999-05-20 | Georges Natsoulis | Procede de caracterisation de cibles genetiques de remplacement |
| AU1009499A (en) * | 1999-01-08 | 2000-11-16 | Johnson & Johnson Research Pty. Limited | Eukaryotic cell-based system for identifying gene modulators |
| US6720139B1 (en) | 1999-01-27 | 2004-04-13 | Elitra Pharmaceuticals, Inc. | Genes identified as required for proliferation in Escherichia coli |
| GB9912965D0 (en) * | 1999-06-03 | 1999-08-04 | Oxford Biomedica Ltd | In vivo selection method |
| EP1203016A2 (fr) * | 1999-08-09 | 2002-05-08 | Incyte Genomics, Inc. | Proteases et inhibiteurs de proteases |
| EP1210429A2 (fr) * | 1999-09-10 | 2002-06-05 | Incyte Genomics, Inc. | Proteines apoptotiques |
| JP2003523756A (ja) * | 2000-02-24 | 2003-08-12 | フィロス インク． | 触媒蛋白質の生成のための改良された方法 |
| AU2001240019A1 (en) * | 2000-03-03 | 2001-09-17 | Incyte Genomics, Inc. | G-protein coupled receptors |
| AU2001266975A1 (en) | 2000-06-16 | 2002-01-02 | Incyte Genomics, Inc. | G-protein coupled receptors |
| US7608704B2 (en) | 2000-11-08 | 2009-10-27 | Incyte Corporation | Secreted proteins |
| AU2003202376B2 (en) | 2002-02-01 | 2008-10-30 | Mcgill University | Oligonucleotides comprising alternating segments and uses thereof |
| WO2003070902A2 (fr) * | 2002-02-20 | 2003-08-28 | Incyte Corporation | Recepteurs et proteines associees aux membranes |
| DE10210284A1 (de) * | 2002-03-08 | 2003-10-02 | Medigene Ag | Verfahren zum Identifizieren von spezifischen RNA-Inhibitoren |
| WO2004012755A1 (fr) * | 2002-08-05 | 2004-02-12 | The Wistar Institute | Methodes de regulation de l'activite d'un complexe renfermant brca1-brca2 |
| AU2003265431A1 (en) * | 2002-08-13 | 2004-02-25 | Incyte Corporation | Cell adhesion and extracellular matrix proteins |
| DE60330468D1 (de) | 2002-08-21 | 2010-01-21 | Revivicor Inc | Schweine ohne jegliche expression funktioneller alpha-1,3-galactosyltransferase |
| US20070219353A1 (en) * | 2002-09-03 | 2007-09-20 | Incyte Corporation | Immune Response Associated Proteins |
| AU2003279829A1 (en) * | 2002-10-04 | 2004-05-04 | Incyte Corp | Protein modification and maintenance molecules |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| US20050164275A1 (en) * | 2002-10-18 | 2005-07-28 | Incyte Corporation | Phosphodiesterases |
| WO2004044166A2 (fr) * | 2002-11-12 | 2004-05-27 | Incyte Corporation | Proteines associees aux glucides |
| WO2004044165A2 (fr) * | 2002-11-13 | 2004-05-27 | Incyte Corporation | Proteines associees aux lipides |
| US20070009516A1 (en) * | 2002-11-26 | 2007-01-11 | Tran Uyen K | Immune response-associated proteins |
| US7635560B2 (en) * | 2003-04-17 | 2009-12-22 | Genesis Group Inc. | Pygopus in diagnosis and treatment of cancer |
| WO2004098539A2 (fr) | 2003-04-30 | 2004-11-18 | Incyte Corporation | Kinases et phosphatases |
| DK1624936T3 (da) * | 2003-05-16 | 2010-03-15 | Univ Laval | CNS-chloridmodulering og anvendelser deraf |
| WO2005110490A1 (fr) * | 2004-05-14 | 2005-11-24 | Universite Laval | Modulation de la phospholipase c gamma et ses utilisations pour la gestion de la douleur et de la nociception |
| JP2008509681A (ja) * | 2004-06-09 | 2008-04-03 | マクギル・ユニバーシテイ | セノラブディティスエレガンス（ｃａｅｎｏｒｈａｂｄｉｔｉｓｅｌｅｇａｎｓ）のアセチルコリン依存性クロライドチャンネルサブユニットをコードするポリヌクレオチド |
| CN101031655A (zh) | 2004-07-26 | 2007-09-05 | 陶氏环球技术公司 | 通过株工程改进蛋白表达的方法 |
| EP1924686A4 (fr) | 2005-08-09 | 2009-11-11 | Revivicor Inc | Ongules transgéniques exprimant la ctla4-ig et leurs utilisations |
| WO2008134461A2 (fr) | 2007-04-27 | 2008-11-06 | Dow Global Technologies, Inc. | Procédé pour rapidement cribler des hôtes microbiens et identifier certaines souches ayant un rendement et/ou une qualité d'expression des protéines hétérologues améliorés |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| GB0806803D0 (en) * | 2008-04-15 | 2008-05-14 | Scottish Biomedical Ltd | Reverse reporter assay |
| ES2865488T3 (es) | 2014-09-05 | 2021-10-15 | Rsem Lp | Composiciones y métodos para el tratamiento y la prevención de la inflamación |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3618638A1 (de) * | 1986-06-03 | 1987-12-10 | Behringwerke Ag | Verfahren zur sekretion von proteinen aus hefen |
| WO1991016456A1 (fr) * | 1990-04-19 | 1991-10-31 | The General Hospital Corporation | Techniques de triage de composes inhibant la liaison de c-myc a l'adn |
| WO1992012635A1 (fr) * | 1991-01-18 | 1992-08-06 | Oncogene Science, Inc. | Procedes de modulation transcriptionnelle de l'expression genetique de genes viraux et d'autres genes |
| JPH07502891A (ja) * | 1991-10-25 | 1995-03-30 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 菌類の二形性遺伝子 |
| IT1255697B (it) * | 1992-09-29 | 1995-11-10 | Enichem Spa | Metodo per l'espressione nel lievito schizosaccharomyces pombe di recettori del sistema nervoso umano |
| AU677834B2 (en) * | 1993-04-07 | 1997-05-08 | Cancer Research Ventures Limited | Methods for screening of substances for therapeutic activityand yeast for use therein |
| US5443962A (en) * | 1993-06-04 | 1995-08-22 | Mitotix, Inc. | Methods of identifying inhibitors of cdc25 phosphatase |
-
1994
- 1994-04-20 AU AUPM5169A patent/AUPM516994A0/en not_active Abandoned
-
1995
- 1995-04-20 WO PCT/AU1995/000235 patent/WO1995029254A1/fr active IP Right Grant
- 1995-04-20 AT AT95916501T patent/ATE222959T1/de not_active IP Right Cessation
- 1995-04-20 CA CA002185550A patent/CA2185550A1/fr not_active Abandoned
- 1995-04-20 US US08/727,449 patent/US5932435A/en not_active Expired - Fee Related
- 1995-04-20 IL IL11343095A patent/IL113430A/xx not_active IP Right Cessation
- 1995-04-20 EP EP95916501A patent/EP0756634B1/fr not_active Expired - Lifetime
- 1995-04-20 ZA ZA953208A patent/ZA953208B/xx unknown
- 1995-04-20 DE DE69527951T patent/DE69527951T2/de not_active Expired - Fee Related
- 1995-04-20 JP JP7527227A patent/JPH09511911A/ja not_active Ceased
-
1996
- 1996-10-17 FI FI964172A patent/FI964172A0/fi not_active Application Discontinuation
- 1996-10-18 NO NO964427A patent/NO964427D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5932435A (en) | 1999-08-03 |
| JPH09511911A (ja) | 1997-12-02 |
| NO964427D0 (no) | 1996-10-18 |
| ZA953208B (en) | 1996-01-03 |
| EP0756634A1 (fr) | 1997-02-05 |
| FI964172A (fi) | 1996-10-17 |
| EP0756634A4 (fr) | 1999-09-01 |
| AUPM516994A0 (en) | 1994-05-12 |
| IL113430A0 (en) | 1995-07-31 |
| ATE222959T1 (de) | 2002-09-15 |
| EP0756634B1 (fr) | 2002-08-28 |
| FI964172A0 (fi) | 1996-10-17 |
| WO1995029254A1 (fr) | 1995-11-02 |
| DE69527951T2 (de) | 2003-04-24 |
| DE69527951D1 (de) | 2002-10-02 |
| CA2185550A1 (fr) | 1995-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |