IL112655A - Substituted cyclohexanol esters, their use in the preparation of medicaments, and pharmaceutical compositions containing them - Google Patents

Substituted cyclohexanol esters, their use in the preparation of medicaments, and pharmaceutical compositions containing them

Info

Publication number
IL112655A
IL112655A IL11265595A IL11265595A IL112655A IL 112655 A IL112655 A IL 112655A IL 11265595 A IL11265595 A IL 11265595A IL 11265595 A IL11265595 A IL 11265595A IL 112655 A IL112655 A IL 112655A
Authority
IL
Israel
Prior art keywords
opt
medicaments
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11265595A
Other languages
English (en)
Other versions
IL112655A0 (en
Original Assignee
Hmr Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hmr Deutschland Gmbh filed Critical Hmr Deutschland Gmbh
Publication of IL112655A0 publication Critical patent/IL112655A0/xx
Publication of IL112655A publication Critical patent/IL112655A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL11265595A 1994-02-16 1995-02-15 Substituted cyclohexanol esters, their use in the preparation of medicaments, and pharmaceutical compositions containing them IL112655A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4404848A DE4404848A1 (de) 1994-02-16 1994-02-16 Substituierte Cyclohexanolester, ihre Verwendung zur Behandlung von Krankheiten und pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
IL112655A0 IL112655A0 (en) 1995-05-26
IL112655A true IL112655A (en) 2003-05-29

Family

ID=6510346

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11265595A IL112655A (en) 1994-02-16 1995-02-15 Substituted cyclohexanol esters, their use in the preparation of medicaments, and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (3) US5567725A (cs)
EP (1) EP0672660B1 (cs)
JP (1) JPH07258220A (cs)
KR (1) KR100360128B1 (cs)
CN (1) CN1051298C (cs)
AT (1) ATE309222T1 (cs)
AU (1) AU679305B2 (cs)
CA (1) CA2142556A1 (cs)
CZ (1) CZ290065B6 (cs)
DE (2) DE4404848A1 (cs)
ES (1) ES2250966T3 (cs)
FI (1) FI950649L (cs)
HU (1) HUT73631A (cs)
IL (1) IL112655A (cs)
NO (1) NO305754B1 (cs)
NZ (1) NZ270490A (cs)
PL (1) PL178970B1 (cs)
RU (1) RU2135465C1 (cs)
SG (1) SG46690A1 (cs)
TW (1) TW295578B (cs)
ZA (1) ZA951220B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL361783A1 (en) * 2000-08-16 2004-10-04 F.Hoffmann-La Roche Ag Novel aminocyclohexane derivatives
CA2447475A1 (en) * 2001-05-25 2002-12-05 Chu-Biao Xue Hydantion derivatives as inhibitors of matrix metalloproteinases
EP2822931B1 (en) 2012-03-09 2017-05-03 Inception 2, Inc. Triazolone compounds and uses thereof
PE20151521A1 (es) 2012-12-20 2015-11-25 Inception 2 Inc Compuestos de triazolona y usos de los mismos
CA2921420A1 (en) 2013-09-06 2015-03-12 Inception 2, Inc. Triazolone compounds and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440117A1 (de) * 1984-11-02 1986-05-15 Bayer Ag, 5090 Leverkusen Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate
GB8512163D0 (en) * 1985-05-14 1985-06-19 Fujisawa Pharmaceutical Co Oxothiazolidine compound
HUT53607A (en) * 1989-01-17 1990-11-28 Hoffmann La Roche Process for production of derivatives of cyclohexan-acetamid
US5015653A (en) * 1989-07-10 1991-05-14 Hoffmann-La Roche Inc. [(5-oxo)-2-pyrrolidinyl)methyl]cyclohexaneacetamides, compositions and use
DE4202184A1 (de) * 1992-01-28 1993-07-29 Hoechst Ag Substituierte salicylaldehyde zur behandlung von krankheiten
TW255880B (cs) * 1992-09-09 1995-09-01 Hoechst Ag
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases

Also Published As

Publication number Publication date
US5567725A (en) 1996-10-22
HUT73631A (en) 1996-08-28
SG46690A1 (en) 1998-02-20
NO950564L (no) 1995-08-17
AU679305B2 (en) 1997-06-26
EP0672660A2 (de) 1995-09-20
RU95101840A (ru) 1996-12-10
CA2142556A1 (en) 1995-08-17
TW295578B (cs) 1997-01-11
ATE309222T1 (de) 2005-11-15
FI950649A7 (fi) 1995-08-17
RU2135465C1 (ru) 1999-08-27
DE4404848A1 (de) 1995-08-17
KR100360128B1 (ko) 2003-04-26
FI950649L (fi) 1995-08-17
PL307284A1 (en) 1995-08-21
PL178970B1 (pl) 2000-07-31
ZA951220B (en) 1995-10-11
CZ290065B6 (cs) 2002-05-15
US5719170A (en) 1998-02-17
CN1126198A (zh) 1996-07-10
EP0672660A3 (de) 1997-05-28
KR950032136A (ko) 1995-12-20
NZ270490A (en) 1996-02-27
JPH07258220A (ja) 1995-10-09
NO305754B1 (no) 1999-07-19
FI950649A0 (fi) 1995-02-14
EP0672660B1 (de) 2005-11-09
DE59511025D1 (de) 2005-12-15
IL112655A0 (en) 1995-05-26
HU9500456D0 (en) 1995-03-28
ES2250966T3 (es) 2006-04-16
NO950564D0 (no) 1995-02-15
CZ37995A3 (en) 1995-09-13
AU1225595A (en) 1995-08-24
US5629311A (en) 1997-05-13
CN1051298C (zh) 2000-04-12

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees