IL112514A0 - Macrocyclic difluorostatone derivatives useful as antiviral agents - Google Patents

Macrocyclic difluorostatone derivatives useful as antiviral agents

Info

Publication number
IL112514A0
IL112514A0 IL11251495A IL11251495A IL112514A0 IL 112514 A0 IL112514 A0 IL 112514A0 IL 11251495 A IL11251495 A IL 11251495A IL 11251495 A IL11251495 A IL 11251495A IL 112514 A0 IL112514 A0 IL 112514A0
Authority
IL
Israel
Prior art keywords
pct
hiv
antiviral agents
macrocyclic
useful
Prior art date
Application number
IL11251495A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL112514A0 publication Critical patent/IL112514A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11251495A 1994-02-04 1995-02-01 Macrocyclic difluorostatone derivatives useful as antiviral agents IL112514A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19208094A 1994-02-04 1994-02-04

Publications (1)

Publication Number Publication Date
IL112514A0 true IL112514A0 (en) 1995-05-26

Family

ID=22708156

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11251495A IL112514A0 (en) 1994-02-04 1995-02-01 Macrocyclic difluorostatone derivatives useful as antiviral agents

Country Status (20)

Country Link
US (1) US5969132A (zh)
EP (1) EP0742791B1 (zh)
JP (1) JP3574455B2 (zh)
KR (1) KR100367379B1 (zh)
CN (1) CN1142830A (zh)
AT (1) ATE198602T1 (zh)
AU (1) AU684875B2 (zh)
CA (1) CA2182476C (zh)
DE (1) DE69426574T2 (zh)
DK (1) DK0742791T3 (zh)
ES (1) ES2155515T3 (zh)
FI (1) FI963073A0 (zh)
GR (1) GR3035623T3 (zh)
HU (1) HUT74384A (zh)
IL (1) IL112514A0 (zh)
NO (1) NO963254D0 (zh)
NZ (1) NZ277410A (zh)
PT (1) PT742791E (zh)
WO (1) WO1995021186A1 (zh)
ZA (1) ZA95756B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672792A5 (zh) * 1985-02-19 1989-12-29 Sandoz Ag
WO1986006379A1 (en) * 1985-04-19 1986-11-06 The Upjohn Company Dihalo-statine substituted renin inhibitors
AU3964489A (en) * 1988-07-08 1990-02-05 Smithkline Beckman Corporation Retroviral protease binding peptides
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
ATE143025T1 (de) * 1991-01-02 1996-10-15 Merrell Pharma Inc Antivirale verbindungen
CA2195125C (en) * 1994-07-15 2003-12-16 Robert A. Farr Difluorostatone antiviral agents

Also Published As

Publication number Publication date
ZA95756B (en) 1995-10-05
ATE198602T1 (de) 2001-01-15
ES2155515T3 (es) 2001-05-16
CN1142830A (zh) 1997-02-12
GR3035623T3 (en) 2001-06-29
WO1995021186A1 (en) 1995-08-10
US5969132A (en) 1999-10-19
EP0742791A1 (en) 1996-11-20
NO963254L (no) 1996-08-02
DE69426574D1 (de) 2001-02-15
AU1262295A (en) 1995-08-21
CA2182476C (en) 2000-12-26
DK0742791T3 (da) 2001-04-02
DE69426574T2 (de) 2001-08-09
KR100367379B1 (ko) 2003-04-11
NZ277410A (en) 1997-02-24
FI963073A (fi) 1996-08-02
EP0742791B1 (en) 2001-01-10
JP3574455B2 (ja) 2004-10-06
NO963254D0 (no) 1996-08-02
JPH09508417A (ja) 1997-08-26
FI963073A0 (fi) 1996-08-02
HUT74384A (en) 1996-12-30
AU684875B2 (en) 1998-01-08
HU9602158D0 (en) 1996-09-30
PT742791E (pt) 2001-06-29

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.