IL111170A - Stable pharmaceutical protein phospholipid compositions and method for their preparation - Google Patents

Stable pharmaceutical protein phospholipid compositions and method for their preparation

Info

Publication number
IL111170A
IL111170A IL11117094A IL11117094A IL111170A IL 111170 A IL111170 A IL 111170A IL 11117094 A IL11117094 A IL 11117094A IL 11117094 A IL11117094 A IL 11117094A IL 111170 A IL111170 A IL 111170A
Authority
IL
Israel
Prior art keywords
protein
preparation
stable pharmaceutical
compositions
pharmaceutical protein
Prior art date
Application number
IL11117094A
Other languages
English (en)
Other versions
IL111170A0 (en
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL111170A0 publication Critical patent/IL111170A0/xx
Publication of IL111170A publication Critical patent/IL111170A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL11117094A 1993-10-06 1994-10-04 Stable pharmaceutical protein phospholipid compositions and method for their preparation IL111170A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13241393A 1993-10-06 1993-10-06

Publications (2)

Publication Number Publication Date
IL111170A0 IL111170A0 (en) 1994-12-29
IL111170A true IL111170A (en) 1999-11-30

Family

ID=22453938

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11117094A IL111170A (en) 1993-10-06 1994-10-04 Stable pharmaceutical protein phospholipid compositions and method for their preparation

Country Status (20)

Country Link
EP (1) EP0671905B1 (es)
JP (1) JP2852127B2 (es)
KR (1) KR100372006B1 (es)
CN (1) CN1206982C (es)
AT (1) ATE222752T1 (es)
AU (1) AU683698B2 (es)
CA (1) CA2150939C (es)
CZ (1) CZ290029B6 (es)
DE (1) DE69431236T2 (es)
DK (1) DK0671905T3 (es)
ES (1) ES2184768T3 (es)
FI (1) FI116271B (es)
HU (1) HUT72326A (es)
IL (1) IL111170A (es)
NO (1) NO314064B1 (es)
NZ (1) NZ274705A (es)
PT (1) PT671905E (es)
RU (1) RU2119791C1 (es)
WO (1) WO1995009611A2 (es)
ZA (1) ZA947782B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874075A (en) * 1993-10-06 1999-02-23 Amgen Inc. Stable protein: phospholipid compositions and methods
EP0937456B1 (en) * 1998-02-23 2004-07-21 Cilag AG International Erythropoietin liposomal dispersion
CA2333162C (en) * 1998-05-25 2011-07-26 Nippon Shinyaku Co., Ltd. Process for producing composite preparation containing nucleic acid
GB0118517D0 (en) * 2001-07-30 2001-09-19 Mitsubishi Tokyo Pharm Inc Compound
US7972593B2 (en) 2004-06-10 2011-07-05 Saint Louis University Delivery of therapeutic agents to the bone
US7863238B2 (en) 2004-06-10 2011-01-04 Saint Louis University Proteins with an attached short peptide of acidic amino acids
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
CN101990425B (zh) 2008-04-08 2016-01-20 默克专利股份有限公司 包含环肽的组合物和使用方法
JP2015519361A (ja) * 2012-05-31 2015-07-09 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ 正電荷有機添加剤での処理によるタンパク質製剤におけるタンパク質−不純物複合体及び凝集体のレベルを低下させるための方法
CA2946275A1 (en) * 2014-04-04 2015-10-08 Osaka University Drug delivery enhancer comprising substance for activating lysophospholipid receptors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2046324A1 (en) * 1989-01-26 1990-07-27 Wen-Ghih Tsang Stabilization of aqueous-based hydrophobic protein solutions and sustained release vehicle
WO1991008754A1 (fr) * 1989-12-13 1991-06-27 Otsuka Pharmaceutical Co., Ltd. Application medicinale de m-csf
DE4208527A1 (de) 1992-03-17 1993-09-23 Max Planck Gesellschaft Liposomen mit negativer ueberschussladung
JPH06247842A (ja) * 1993-02-23 1994-09-06 Green Cross Corp:The リポソーム組成物の製造方法

Also Published As

Publication number Publication date
IL111170A0 (en) 1994-12-29
CA2150939C (en) 2001-05-01
AU7923994A (en) 1995-05-01
KR100372006B1 (ko) 2003-07-18
FI952738L (fi) 1995-07-31
AU683698B2 (en) 1997-11-20
ATE222752T1 (de) 2002-09-15
EP0671905A1 (en) 1995-09-20
WO1995009611A3 (en) 1995-06-22
EP0671905B1 (en) 2002-08-28
HU9502053D0 (en) 1995-10-30
CN1206982C (zh) 2005-06-22
NO314064B1 (no) 2003-01-27
DE69431236D1 (de) 2002-10-02
RU2119791C1 (ru) 1998-10-10
FI952738A0 (fi) 1995-06-05
NO952210L (no) 1995-08-04
NO952210D0 (no) 1995-06-02
NZ274705A (en) 1997-12-19
ES2184768T3 (es) 2003-04-16
JP2852127B2 (ja) 1999-01-27
CZ290029B6 (cs) 2002-05-15
DK0671905T3 (da) 2002-10-07
CN1117266A (zh) 1996-02-21
JPH08505403A (ja) 1996-06-11
ZA947782B (en) 1995-05-17
WO1995009611A2 (en) 1995-04-13
CZ143895A3 (en) 1996-01-17
HK1010341A1 (en) 1999-06-17
DE69431236T2 (de) 2003-01-02
FI116271B (fi) 2005-10-31
CA2150939A1 (en) 1995-04-13
KR960700042A (ko) 1996-01-19
HUT72326A (en) 1996-04-29
PT671905E (pt) 2002-12-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees