IL87778A - Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation - Google Patents

Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation

Info

Publication number
IL87778A
IL87778A IL87778A IL8777888A IL87778A IL 87778 A IL87778 A IL 87778A IL 87778 A IL87778 A IL 87778A IL 8777888 A IL8777888 A IL 8777888A IL 87778 A IL87778 A IL 87778A
Authority
IL
Israel
Prior art keywords
therapeutically active
preparation
pharmaceutical compositions
active proteins
topical pharmaceutical
Prior art date
Application number
IL87778A
Other versions
IL87778A0 (en
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IL87778A0 publication Critical patent/IL87778A0/en
Publication of IL87778A publication Critical patent/IL87778A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The pharmaceutical preparations are for topical use, contain one or more stabilised therapeutically active proteins and, where appropriate, customary auxiliaries, vehicles and additives, and are prepared as described using physiologically tolerated hydrophobic substances for stabilising proteins.
IL87778A 1987-09-17 1988-09-16 Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation IL87778A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731255 DE3731255A1 (en) 1987-09-17 1987-09-17 Stabilization of therapeutically active proteins in pharmaceutical preparations

Publications (2)

Publication Number Publication Date
IL87778A0 IL87778A0 (en) 1989-03-31
IL87778A true IL87778A (en) 1993-05-13

Family

ID=6336244

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87778A IL87778A (en) 1987-09-17 1988-09-16 Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation

Country Status (20)

Country Link
EP (1) EP0307857B1 (en)
JP (1) JP2783552B2 (en)
KR (1) KR970008112B1 (en)
AT (1) ATE126063T1 (en)
AU (1) AU615473B2 (en)
CA (1) CA1329121C (en)
DD (1) DD274562A5 (en)
DE (2) DE3731255A1 (en)
DK (1) DK516288A (en)
ES (1) ES2077559T3 (en)
FI (1) FI95770C (en)
GR (1) GR3017432T3 (en)
HU (1) HU203045B (en)
IE (1) IE70908B1 (en)
IL (1) IL87778A (en)
NO (1) NO179436C (en)
NZ (1) NZ226209A (en)
PT (1) PT88539B (en)
RU (1) RU2093145C1 (en)
ZA (1) ZA886903B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
JPH0776527A (en) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc Semi-solid preparation and method for producing the same
RU2132184C1 (en) * 1998-12-16 1999-06-27 Краснодарская научно-исследовательская ветеринарная станция Method of preparing composition "zhiroform-plus" for treatment and prophylaxis of endometritis in cows
HU230383B1 (en) * 2000-07-14 2016-03-29 Allergan, Inc Use of solubility enhancing component in an aqueous composition comprising brimodinine-tartarte
RU2216313C2 (en) * 2000-12-25 2003-11-20 Савченков Сергей Николаевич Curative-prophylactic cosmetic agent
RU2188665C1 (en) * 2001-04-09 2002-09-10 Щербакова Элеонора Григорьевна Antiviral and antibacterial agent "interlisin"
ITMI20031640A1 (en) * 2003-08-08 2005-02-09 Mipharm S P A BASE FOR BIOADHESIVE GEL.
CU23432B6 (en) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech STABILIZED FORMULATIONS CONTAINING GAMMA AND ALFA INTERFERONS IN POTENTIAL PROPORTIONS
BR112012028194A2 (en) * 2010-05-04 2017-08-08 Viscogel Ab composition and process for preparing the composition
RU2431489C1 (en) * 2010-05-25 2011-10-20 Федеральное государственное учреждение "Российский научный центр рентгенорадиологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "РНЦРР Росмедтехнологий") Method of treating chronic inflammatory bowel diseases
AU2018282905B2 (en) 2017-06-12 2022-06-02 Lakewood Amedex, Inc Bisphosphocin gel formulations and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5413223A (en) * 1977-07-01 1979-01-31 Ricoh Co Ltd Printer unit
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
FR2513124B1 (en) * 1981-07-21 1989-11-17 Hayashibara Biochem Lab PRODUCTION AND APPLICATIONS OF THE TARGET CELL LYSE FACTOR
CA1190148A (en) * 1981-10-13 1985-07-09 Samuel S. Asculai Interferon-containing compositions
JPS5892622A (en) * 1981-11-28 1983-06-02 Sunstar Inc Pharmaceutical preparation containing stably compounded interferon
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
JPS5910524A (en) * 1982-07-08 1984-01-20 Toray Ind Inc Interferon composition and its preparation
JPS6061535A (en) * 1983-08-24 1985-04-09 エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト Pharmaceutical composition
EP0177342A3 (en) * 1984-10-04 1987-12-02 Genentech, Inc. Oral formulation of therapeutic proteins
DE3603444A1 (en) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K PHARMACEUTICAL PREPARATIONS FOR STABILIZING INTERFERON ALPHA
US4822605A (en) * 1986-02-18 1989-04-18 Exovir, Inc. Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like

Also Published As

Publication number Publication date
PT88539B (en) 1992-11-30
IE882812L (en) 1989-03-17
DE3731255A1 (en) 1989-04-06
FI884240A0 (en) 1988-09-15
HUT47436A (en) 1989-03-28
JP2783552B2 (en) 1998-08-06
JPH01102029A (en) 1989-04-19
CA1329121C (en) 1994-05-03
AU615473B2 (en) 1991-10-03
ZA886903B (en) 1990-05-30
FI95770B (en) 1995-12-15
HU203045B (en) 1991-05-28
DK516288D0 (en) 1988-09-16
NO884123D0 (en) 1988-09-16
ES2077559T3 (en) 1995-12-01
KR970008112B1 (en) 1997-05-21
IL87778A0 (en) 1989-03-31
DK516288A (en) 1989-03-18
FI95770C (en) 1996-03-25
EP0307857A1 (en) 1989-03-22
KR890004719A (en) 1989-05-09
GR3017432T3 (en) 1995-12-31
NO884123L (en) 1989-03-20
AU2231688A (en) 1989-03-23
EP0307857B1 (en) 1995-08-09
ATE126063T1 (en) 1995-08-15
IE70908B1 (en) 1997-01-15
NZ226209A (en) 1991-06-25
NO179436C (en) 1996-10-09
PT88539A (en) 1988-10-01
RU2093145C1 (en) 1997-10-20
NO179436B (en) 1996-07-01
DE3854290D1 (en) 1995-09-14
FI884240L (en) 1989-03-18
DD274562A5 (en) 1989-12-27

Similar Documents

Publication Publication Date Title
EP0275005A3 (en) Complex compounds of bioflavonoids with phospholipids, their preparation and use, and pharmaceutical and cosmetic compositions containing them
ZA896287B (en) Pharmaceutical combination preparations for use in anti-neoplastic therapy
ZA885192B (en) Pharmaceutical preparations
EP0283713A3 (en) Complexes of saponins with phospholipids and pharmaceutical and cosmetic compositions containing them
CA2005143A1 (en) Stabilized hydrophobic protein formulations of g-csf
IL87778A (en) Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation
WO1987003480A3 (en) Medicament with anti-tumoral action containing hexadecylphosphocholine
AU1099288A (en) Drug delivery system and method of making the same
MY105121A (en) Pharmaceutical composition for systemic transdermal administration.
DK642587A (en) INSULIN PREPARATION
PT97160A (en) Process for the preparation of stable compositions for parenteral administration containing a biologically active protein, polypeptide or polypeptide
ATE148630T1 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING STABILIZED DERIVATIVES OF VITAMIN D2 AND D3
PT996462E (en) PREPARATIONS OF PHARMACEUTICAL COMBINATIONS CONTAINING ERYTHROPOIETIN AND MODIFIED HEMOGLOBINS
TW290455B (en)
AU563762B2 (en) S-adenosyl-l-methionine salts preparation
AU1518492A (en) Pharmaceutical compositions for transcutaneous administration
AU4150489A (en) Micronised drug formulation
AU536582B2 (en) Plenylpiperazine derivatives of 1,3,4-oxiadiazolylphends
EP0351876A3 (en) Composition for potentiating vaccination effect
IL85651A0 (en) Optically active oxo-isoindolinyl derivatives,their preparation and pharmaceutical compositions containing them
AU2506188A (en) Azelastine embonate, processes for its preparation and pharmaceutical formulations which contain azelastine embonate as active substance

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXTN Extension order renewed