IL87778A - Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation - Google Patents

Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation

Info

Publication number
IL87778A
IL87778A IL87778A IL8777888A IL87778A IL 87778 A IL87778 A IL 87778A IL 87778 A IL87778 A IL 87778A IL 8777888 A IL8777888 A IL 8777888A IL 87778 A IL87778 A IL 87778A
Authority
IL
Israel
Prior art keywords
therapeutically active
preparation
pharmaceutical compositions
active proteins
topical pharmaceutical
Prior art date
Application number
IL87778A
Other versions
IL87778A0 (en
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IL87778A0 publication Critical patent/IL87778A0/en
Publication of IL87778A publication Critical patent/IL87778A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Abstract

The pharmaceutical preparations are for topical use, contain one or more stabilised therapeutically active proteins and, where appropriate, customary auxiliaries, vehicles and additives, and are prepared as described using physiologically tolerated hydrophobic substances for stabilising proteins.
IL87778A 1987-09-17 1988-09-16 Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation IL87778A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731255 DE3731255A1 (en) 1987-09-17 1987-09-17 Stabilization of therapeutically active proteins in pharmaceutical preparations

Publications (2)

Publication Number Publication Date
IL87778A0 IL87778A0 (en) 1989-03-31
IL87778A true IL87778A (en) 1993-05-13

Family

ID=6336244

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87778A IL87778A (en) 1987-09-17 1988-09-16 Topical pharmaceutical compositions in the form of a hydrogel containing stabilized therapeutically active proteins and their preparation

Country Status (20)

Country Link
EP (1) EP0307857B1 (en)
JP (1) JP2783552B2 (en)
KR (1) KR970008112B1 (en)
AT (1) ATE126063T1 (en)
AU (1) AU615473B2 (en)
CA (1) CA1329121C (en)
DD (1) DD274562A5 (en)
DE (2) DE3731255A1 (en)
DK (1) DK516288A (en)
ES (1) ES2077559T3 (en)
FI (1) FI95770C (en)
GR (1) GR3017432T3 (en)
HU (1) HU203045B (en)
IE (1) IE70908B1 (en)
IL (1) IL87778A (en)
NO (1) NO179436C (en)
NZ (1) NZ226209A (en)
PT (1) PT88539B (en)
RU (1) RU2093145C1 (en)
ZA (1) ZA886903B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
JPH0776527A (en) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc Semi-solid preparation and production thereof
ITMI20031640A1 (en) * 2003-08-08 2005-02-09 Mipharm S P A BASE FOR BIOADHESIVE GEL.
CU23432B6 (en) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech STABILIZED FORMULATIONS CONTAINING GAMMA AND ALFA INTERFERONS IN POTENTIAL PROPORTIONS
ES2454776T3 (en) * 2010-05-04 2014-04-11 Viscogel Ab Chitosan composition
BR122021011439B1 (en) * 2017-06-12 2022-03-29 Lakewood Amedex, Inc Bisphosphocine gel formulation and uses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5413223A (en) * 1977-07-01 1979-01-31 Ricoh Co Ltd Printer unit
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
FR2513124B1 (en) * 1981-07-21 1989-11-17 Hayashibara Biochem Lab PRODUCTION AND APPLICATIONS OF THE TARGET CELL LYSE FACTOR
CA1190148A (en) * 1981-10-13 1985-07-09 Samuel S. Asculai Interferon-containing compositions
JPS5892622A (en) * 1981-11-28 1983-06-02 Sunstar Inc Pharmaceutical preparation containing stably compounded interferon
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
JPS5910524A (en) * 1982-07-08 1984-01-20 Toray Ind Inc Interferon composition and its preparation
JPS6061535A (en) * 1983-08-24 1985-04-09 エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト Pharmaceutical composition
EP0177342A3 (en) * 1984-10-04 1987-12-02 Genentech, Inc. Oral formulation of therapeutic proteins
DE3603444A1 (en) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K PHARMACEUTICAL PREPARATIONS FOR STABILIZING INTERFERON ALPHA
US4822605A (en) * 1986-02-18 1989-04-18 Exovir, Inc. Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like

Also Published As

Publication number Publication date
PT88539A (en) 1988-10-01
JP2783552B2 (en) 1998-08-06
NO884123L (en) 1989-03-20
ES2077559T3 (en) 1995-12-01
FI95770B (en) 1995-12-15
KR890004719A (en) 1989-05-09
EP0307857B1 (en) 1995-08-09
RU2093145C1 (en) 1997-10-20
ATE126063T1 (en) 1995-08-15
KR970008112B1 (en) 1997-05-21
JPH01102029A (en) 1989-04-19
DK516288A (en) 1989-03-18
FI884240A (en) 1989-03-18
GR3017432T3 (en) 1995-12-31
DK516288D0 (en) 1988-09-16
ZA886903B (en) 1990-05-30
AU2231688A (en) 1989-03-23
AU615473B2 (en) 1991-10-03
DE3854290D1 (en) 1995-09-14
NO179436C (en) 1996-10-09
DE3731255A1 (en) 1989-04-06
IL87778A0 (en) 1989-03-31
EP0307857A1 (en) 1989-03-22
FI884240A0 (en) 1988-09-15
PT88539B (en) 1992-11-30
IE882812L (en) 1989-03-17
NO884123D0 (en) 1988-09-16
HU203045B (en) 1991-05-28
IE70908B1 (en) 1997-01-15
FI95770C (en) 1996-03-25
DD274562A5 (en) 1989-12-27
NO179436B (en) 1996-07-01
CA1329121C (en) 1994-05-03
NZ226209A (en) 1991-06-25
HUT47436A (en) 1989-03-28

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Legal Events

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KB Patent renewed
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