NO179436C - Process for the manufacture of pharmaceutical products for topical use - Google Patents

Process for the manufacture of pharmaceutical products for topical use

Info

Publication number
NO179436C
NO179436C NO884123A NO884123A NO179436C NO 179436 C NO179436 C NO 179436C NO 884123 A NO884123 A NO 884123A NO 884123 A NO884123 A NO 884123A NO 179436 C NO179436 C NO 179436C
Authority
NO
Norway
Prior art keywords
topical use
manufacture
pharmaceutical products
proteins
stabilised
Prior art date
Application number
NO884123A
Other languages
Norwegian (no)
Other versions
NO884123L (en
NO884123D0 (en
NO179436B (en
Inventor
Traute Mundorf
Kurt Schnecker
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO884123D0 publication Critical patent/NO884123D0/en
Publication of NO884123L publication Critical patent/NO884123L/en
Publication of NO179436B publication Critical patent/NO179436B/en
Publication of NO179436C publication Critical patent/NO179436C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Abstract

The pharmaceutical preparations are for topical use, contain one or more stabilised therapeutically active proteins and, where appropriate, customary auxiliaries, vehicles and additives, and are prepared as described using physiologically tolerated hydrophobic substances for stabilising proteins.
NO884123A 1987-09-17 1988-09-16 Process for the manufacture of pharmaceutical products for topical use NO179436C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731255 DE3731255A1 (en) 1987-09-17 1987-09-17 Stabilization of therapeutically active proteins in pharmaceutical preparations

Publications (4)

Publication Number Publication Date
NO884123D0 NO884123D0 (en) 1988-09-16
NO884123L NO884123L (en) 1989-03-20
NO179436B NO179436B (en) 1996-07-01
NO179436C true NO179436C (en) 1996-10-09

Family

ID=6336244

Family Applications (1)

Application Number Title Priority Date Filing Date
NO884123A NO179436C (en) 1987-09-17 1988-09-16 Process for the manufacture of pharmaceutical products for topical use

Country Status (20)

Country Link
EP (1) EP0307857B1 (en)
JP (1) JP2783552B2 (en)
KR (1) KR970008112B1 (en)
AT (1) ATE126063T1 (en)
AU (1) AU615473B2 (en)
CA (1) CA1329121C (en)
DD (1) DD274562A5 (en)
DE (2) DE3731255A1 (en)
DK (1) DK516288A (en)
ES (1) ES2077559T3 (en)
FI (1) FI95770C (en)
GR (1) GR3017432T3 (en)
HU (1) HU203045B (en)
IE (1) IE70908B1 (en)
IL (1) IL87778A (en)
NO (1) NO179436C (en)
NZ (1) NZ226209A (en)
PT (1) PT88539B (en)
RU (1) RU2093145C1 (en)
ZA (1) ZA886903B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
JPH0776527A (en) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc Semi-solid preparation and production thereof
ITMI20031640A1 (en) * 2003-08-08 2005-02-09 Mipharm S P A BASE FOR BIOADHESIVE GEL.
CU23432B6 (en) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech STABILIZED FORMULATIONS CONTAINING GAMMA AND ALFA INTERFERONS IN POTENTIAL PROPORTIONS
MX2012012776A (en) * 2010-05-04 2013-04-19 Viscogel Ab Chitosan composition.
JP7148994B2 (en) * 2017-06-12 2022-10-06 レイクウッド アメディックス、インコーポレイテッド Bisphosphosingel preparation and its use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5413223A (en) * 1977-07-01 1979-01-31 Ricoh Co Ltd Printer unit
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
SE8204382L (en) * 1981-07-21 1983-01-22 Hayashibara Biochem Lab PUT TO MAKE MALCELLY FACTOR AND USE THEREOF
CA1190148A (en) * 1981-10-13 1985-07-09 Samuel S. Asculai Interferon-containing compositions
JPS5892622A (en) * 1981-11-28 1983-06-02 Sunstar Inc Pharmaceutical preparation containing stably compounded interferon
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
JPS5910524A (en) * 1982-07-08 1984-01-20 Toray Ind Inc Interferon composition and its preparation
JPS6061535A (en) * 1983-08-24 1985-04-09 エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト Pharmaceutical composition
EP0177342A3 (en) * 1984-10-04 1987-12-02 Genentech, Inc. Oral formulation of therapeutic proteins
DE3603444A1 (en) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K PHARMACEUTICAL PREPARATIONS FOR STABILIZING INTERFERON ALPHA
US4822605A (en) * 1986-02-18 1989-04-18 Exovir, Inc. Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like

Also Published As

Publication number Publication date
HU203045B (en) 1991-05-28
DE3731255A1 (en) 1989-04-06
IE70908B1 (en) 1997-01-15
IL87778A0 (en) 1989-03-31
DE3854290D1 (en) 1995-09-14
NZ226209A (en) 1991-06-25
ZA886903B (en) 1990-05-30
NO884123L (en) 1989-03-20
CA1329121C (en) 1994-05-03
RU2093145C1 (en) 1997-10-20
FI95770B (en) 1995-12-15
DK516288A (en) 1989-03-18
KR890004719A (en) 1989-05-09
ATE126063T1 (en) 1995-08-15
DK516288D0 (en) 1988-09-16
PT88539A (en) 1988-10-01
PT88539B (en) 1992-11-30
GR3017432T3 (en) 1995-12-31
EP0307857B1 (en) 1995-08-09
JPH01102029A (en) 1989-04-19
AU615473B2 (en) 1991-10-03
IL87778A (en) 1993-05-13
FI95770C (en) 1996-03-25
IE882812L (en) 1989-03-17
EP0307857A1 (en) 1989-03-22
NO884123D0 (en) 1988-09-16
DD274562A5 (en) 1989-12-27
FI884240A0 (en) 1988-09-15
JP2783552B2 (en) 1998-08-06
FI884240A (en) 1989-03-18
NO179436B (en) 1996-07-01
KR970008112B1 (en) 1997-05-21
AU2231688A (en) 1989-03-23
HUT47436A (en) 1989-03-28
ES2077559T3 (en) 1995-12-01

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Legal Events

Date Code Title Description
MK1K Patent expired