FI884240A0 - Process for the preparation of a topical pharmaceutical product - Google Patents

Process for the preparation of a topical pharmaceutical product

Info

Publication number
FI884240A0
FI884240A0 FI884240A FI884240A FI884240A0 FI 884240 A0 FI884240 A0 FI 884240A0 FI 884240 A FI884240 A FI 884240A FI 884240 A FI884240 A FI 884240A FI 884240 A0 FI884240 A0 FI 884240A0
Authority
FI
Finland
Prior art keywords
preparation
pharmaceutical product
topical pharmaceutical
proteins
stabilised
Prior art date
Application number
FI884240A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI95770C (en
FI884240A (en
FI95770B (en
Inventor
Traute Mundorf
Kurt Schnecker
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of FI884240A0 publication Critical patent/FI884240A0/en
Publication of FI884240A publication Critical patent/FI884240A/en
Application granted granted Critical
Publication of FI95770B publication Critical patent/FI95770B/en
Publication of FI95770C publication Critical patent/FI95770C/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/217IFN-gamma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The pharmaceutical preparations are for topical use, contain one or more stabilised therapeutically active proteins and, where appropriate, customary auxiliaries, vehicles and additives, and are prepared as described using physiologically tolerated hydrophobic substances for stabilising proteins.
FI884240A 1987-09-17 1988-09-15 A process for the preparation of a pharmaceutical preparation for topical use FI95770C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873731255 DE3731255A1 (en) 1987-09-17 1987-09-17 Stabilization of therapeutically active proteins in pharmaceutical preparations
DE3731255 1987-09-17

Publications (4)

Publication Number Publication Date
FI884240A0 true FI884240A0 (en) 1988-09-15
FI884240A FI884240A (en) 1989-03-18
FI95770B FI95770B (en) 1995-12-15
FI95770C FI95770C (en) 1996-03-25

Family

ID=6336244

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884240A FI95770C (en) 1987-09-17 1988-09-15 A process for the preparation of a pharmaceutical preparation for topical use

Country Status (20)

Country Link
EP (1) EP0307857B1 (en)
JP (1) JP2783552B2 (en)
KR (1) KR970008112B1 (en)
AT (1) ATE126063T1 (en)
AU (1) AU615473B2 (en)
CA (1) CA1329121C (en)
DD (1) DD274562A5 (en)
DE (2) DE3731255A1 (en)
DK (1) DK516288A (en)
ES (1) ES2077559T3 (en)
FI (1) FI95770C (en)
GR (1) GR3017432T3 (en)
HU (1) HU203045B (en)
IE (1) IE70908B1 (en)
IL (1) IL87778A (en)
NO (1) NO179436C (en)
NZ (1) NZ226209A (en)
PT (1) PT88539B (en)
RU (1) RU2093145C1 (en)
ZA (1) ZA886903B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
JPH0776527A (en) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc Semi-solid preparation and production thereof
ITMI20031640A1 (en) * 2003-08-08 2005-02-09 Mipharm S P A BASE FOR BIOADHESIVE GEL.
CU23432B6 (en) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech STABILIZED FORMULATIONS CONTAINING GAMMA AND ALFA INTERFERONS IN POTENTIAL PROPORTIONS
MX2012012776A (en) 2010-05-04 2013-04-19 Viscogel Ab Chitosan composition.
DK3638251T3 (en) * 2017-06-12 2024-05-13 Lakewood Amedex Inc BISPHOSPHOCINE GEL FORMULATIONS AND USES THEREOF

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5413223A (en) * 1977-07-01 1979-01-31 Ricoh Co Ltd Printer unit
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
FR2513124B1 (en) * 1981-07-21 1989-11-17 Hayashibara Biochem Lab PRODUCTION AND APPLICATIONS OF THE TARGET CELL LYSE FACTOR
CA1190148A (en) * 1981-10-13 1985-07-09 Samuel S. Asculai Interferon-containing compositions
JPS5892622A (en) * 1981-11-28 1983-06-02 Sunstar Inc Pharmaceutical preparation containing stably compounded interferon
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
JPS5910524A (en) * 1982-07-08 1984-01-20 Toray Ind Inc Interferon composition and its preparation
JPS6061535A (en) * 1983-08-24 1985-04-09 エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト Pharmaceutical composition
EP0177342A3 (en) * 1984-10-04 1987-12-02 Genentech, Inc. Oral formulation of therapeutic proteins
DE3603444A1 (en) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K PHARMACEUTICAL PREPARATIONS FOR STABILIZING INTERFERON ALPHA
US4822605A (en) * 1986-02-18 1989-04-18 Exovir, Inc. Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like

Also Published As

Publication number Publication date
IE70908B1 (en) 1997-01-15
ES2077559T3 (en) 1995-12-01
IL87778A0 (en) 1989-03-31
IL87778A (en) 1993-05-13
ZA886903B (en) 1990-05-30
JPH01102029A (en) 1989-04-19
FI95770C (en) 1996-03-25
EP0307857A1 (en) 1989-03-22
DE3731255A1 (en) 1989-04-06
EP0307857B1 (en) 1995-08-09
FI884240A (en) 1989-03-18
HUT47436A (en) 1989-03-28
RU2093145C1 (en) 1997-10-20
GR3017432T3 (en) 1995-12-31
AU2231688A (en) 1989-03-23
NO884123L (en) 1989-03-20
FI95770B (en) 1995-12-15
NO179436B (en) 1996-07-01
IE882812L (en) 1989-03-17
PT88539A (en) 1988-10-01
KR890004719A (en) 1989-05-09
DK516288D0 (en) 1988-09-16
JP2783552B2 (en) 1998-08-06
PT88539B (en) 1992-11-30
AU615473B2 (en) 1991-10-03
NO884123D0 (en) 1988-09-16
NO179436C (en) 1996-10-09
HU203045B (en) 1991-05-28
DE3854290D1 (en) 1995-09-14
DD274562A5 (en) 1989-12-27
DK516288A (en) 1989-03-18
NZ226209A (en) 1991-06-25
CA1329121C (en) 1994-05-03
KR970008112B1 (en) 1997-05-21
ATE126063T1 (en) 1995-08-15

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH

MA Patent expired