IL110051A - Derivatives of nucleoside based attached to beta-substituted butanols and pharmaceutical compositions containing them - Google Patents

Derivatives of nucleoside based attached to beta-substituted butanols and pharmaceutical compositions containing them

Info

Publication number
IL110051A
IL110051A IL11005194A IL11005194A IL110051A IL 110051 A IL110051 A IL 110051A IL 11005194 A IL11005194 A IL 11005194A IL 11005194 A IL11005194 A IL 11005194A IL 110051 A IL110051 A IL 110051A
Authority
IL
Israel
Prior art keywords
group
hydrogen
derivatives
butanols
beta
Prior art date
Application number
IL11005194A
Other languages
English (en)
Other versions
IL110051A0 (en
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL110051A0 publication Critical patent/IL110051A0/xx
Publication of IL110051A publication Critical patent/IL110051A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11005194A 1993-06-23 1994-06-20 Derivatives of nucleoside based attached to beta-substituted butanols and pharmaceutical compositions containing them IL110051A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8172793A 1993-06-23 1993-06-23

Publications (2)

Publication Number Publication Date
IL110051A0 IL110051A0 (en) 1994-10-07
IL110051A true IL110051A (en) 2000-01-31

Family

ID=22166006

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11005194A IL110051A (en) 1993-06-23 1994-06-20 Derivatives of nucleoside based attached to beta-substituted butanols and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US6017923A (ja)
EP (1) EP0705264B1 (ja)
JP (1) JP3468423B2 (ja)
CN (1) CN1040759C (ja)
AT (1) ATE178605T1 (ja)
AU (1) AU679763B2 (ja)
CA (1) CA2165419C (ja)
DE (1) DE69417748T2 (ja)
DK (1) DK0705264T3 (ja)
ES (1) ES2132411T3 (ja)
FI (1) FI956246A0 (ja)
GR (1) GR3030003T3 (ja)
HU (1) HUT73410A (ja)
IL (1) IL110051A (ja)
NO (1) NO955254L (ja)
NZ (1) NZ268479A (ja)
TW (1) TW269690B (ja)
WO (1) WO1995000515A1 (ja)
ZA (1) ZA944344B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69940423D1 (de) 1998-01-30 2009-04-02 Daiso Co Ltd Verfahren zur herstellung von butantriol-derivaten

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199575A (en) * 1978-03-27 1980-04-22 Gunther Roland E Method of treating dermatitis venenata
US4221794A (en) * 1979-06-21 1980-09-09 Newport Pharmaceuticals International, Inc. Method of imparting immunomodulating and antiviral activity
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4935427A (en) * 1987-12-31 1990-06-19 The United States Of America As Represented By The Department Of Health And Human Services Pyrimidine and purine 1,2-butadiene-4-ols as anti-retroviral agents
US5043339A (en) * 1988-12-19 1991-08-27 Burroughs Wellcome Co. Antiviral compounds

Also Published As

Publication number Publication date
CA2165419C (en) 1999-03-02
AU7139494A (en) 1995-01-17
FI956246A (fi) 1995-12-22
CA2165419A1 (en) 1994-12-24
EP0705264A1 (en) 1996-04-10
HUT73410A (en) 1996-07-29
CN1040759C (zh) 1998-11-18
TW269690B (ja) 1996-02-01
CN1125947A (zh) 1996-07-03
ZA944344B (en) 1995-02-15
DK0705264T3 (da) 1999-10-18
GR3030003T3 (en) 1999-07-30
NO955254L (no) 1996-02-21
FI956246A0 (fi) 1995-12-22
US6017923A (en) 2000-01-25
AU679763B2 (en) 1997-07-10
ATE178605T1 (de) 1999-04-15
JPH08512030A (ja) 1996-12-17
DE69417748D1 (de) 1999-05-12
NZ268479A (en) 1997-07-27
DE69417748T2 (de) 1999-08-19
IL110051A0 (en) 1994-10-07
JP3468423B2 (ja) 2003-11-17
EP0705264B1 (en) 1999-04-07
ES2132411T3 (es) 1999-08-16
HU9503707D0 (en) 1996-02-28
WO1995000515A1 (en) 1995-01-05
NO955254D0 (no) 1995-12-22

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Legal Events

Date Code Title Description
FF Patent granted
RH Patent void