FI956246A0 - Hiili-asykliset nukleosidijohdannaiset antiviraalisina ja antineoplastisina aineina - Google Patents

Hiili-asykliset nukleosidijohdannaiset antiviraalisina ja antineoplastisina aineina

Info

Publication number
FI956246A0
FI956246A0 FI956246A FI956246A FI956246A0 FI 956246 A0 FI956246 A0 FI 956246A0 FI 956246 A FI956246 A FI 956246A FI 956246 A FI956246 A FI 956246A FI 956246 A0 FI956246 A0 FI 956246A0
Authority
FI
Finland
Prior art keywords
group
hydrogen
antiviral
antineoplastic agents
nucleoside derivatives
Prior art date
Application number
FI956246A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI956246A (fi
Inventor
Jeffrey Stephen Sabol
Sai Prasad Sunkara
Shawn Christopher Miller
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI956246A publication Critical patent/FI956246A/fi
Publication of FI956246A0 publication Critical patent/FI956246A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI956246A 1993-06-23 1995-12-22 Hiili-asykliset nukleosidijohdannaiset antiviraalisina ja antineoplastisina aineina FI956246A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8172793A 1993-06-23 1993-06-23
PCT/US1994/006119 WO1995000515A1 (en) 1993-06-23 1994-05-31 Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents

Publications (2)

Publication Number Publication Date
FI956246A FI956246A (fi) 1995-12-22
FI956246A0 true FI956246A0 (fi) 1995-12-22

Family

ID=22166006

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956246A FI956246A0 (fi) 1993-06-23 1995-12-22 Hiili-asykliset nukleosidijohdannaiset antiviraalisina ja antineoplastisina aineina

Country Status (19)

Country Link
US (1) US6017923A (ja)
EP (1) EP0705264B1 (ja)
JP (1) JP3468423B2 (ja)
CN (1) CN1040759C (ja)
AT (1) ATE178605T1 (ja)
AU (1) AU679763B2 (ja)
CA (1) CA2165419C (ja)
DE (1) DE69417748T2 (ja)
DK (1) DK0705264T3 (ja)
ES (1) ES2132411T3 (ja)
FI (1) FI956246A0 (ja)
GR (1) GR3030003T3 (ja)
HU (1) HUT73410A (ja)
IL (1) IL110051A (ja)
NO (1) NO955254L (ja)
NZ (1) NZ268479A (ja)
TW (1) TW269690B (ja)
WO (1) WO1995000515A1 (ja)
ZA (1) ZA944344B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620977B1 (en) 1998-01-30 2003-09-16 Daiso Co., Ltd. Process for producing butanetriol derivative

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199575A (en) * 1978-03-27 1980-04-22 Gunther Roland E Method of treating dermatitis venenata
US4221794A (en) * 1979-06-21 1980-09-09 Newport Pharmaceuticals International, Inc. Method of imparting immunomodulating and antiviral activity
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4935427A (en) * 1987-12-31 1990-06-19 The United States Of America As Represented By The Department Of Health And Human Services Pyrimidine and purine 1,2-butadiene-4-ols as anti-retroviral agents
CA2005815C (en) * 1988-12-19 1999-08-03 Wellcome Foundation Limited (The) Antiviral acyclic nucleoside derivatives

Also Published As

Publication number Publication date
NZ268479A (en) 1997-07-27
AU7139494A (en) 1995-01-17
HU9503707D0 (en) 1996-02-28
DE69417748T2 (de) 1999-08-19
IL110051A (en) 2000-01-31
EP0705264A1 (en) 1996-04-10
CA2165419C (en) 1999-03-02
CN1125947A (zh) 1996-07-03
AU679763B2 (en) 1997-07-10
TW269690B (ja) 1996-02-01
JP3468423B2 (ja) 2003-11-17
EP0705264B1 (en) 1999-04-07
US6017923A (en) 2000-01-25
GR3030003T3 (en) 1999-07-30
WO1995000515A1 (en) 1995-01-05
HUT73410A (en) 1996-07-29
NO955254L (no) 1996-02-21
ES2132411T3 (es) 1999-08-16
DK0705264T3 (da) 1999-10-18
CN1040759C (zh) 1998-11-18
DE69417748D1 (de) 1999-05-12
ATE178605T1 (de) 1999-04-15
FI956246A (fi) 1995-12-22
JPH08512030A (ja) 1996-12-17
IL110051A0 (en) 1994-10-07
NO955254D0 (no) 1995-12-22
ZA944344B (en) 1995-02-15
CA2165419A1 (en) 1994-12-24

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Legal Events

Date Code Title Description
MA Patent expired