DE69417748D1 - Carbo-acyclische nukleosidderivate als antivirale und antineoplastische mittel - Google Patents
Carbo-acyclische nukleosidderivate als antivirale und antineoplastische mittelInfo
- Publication number
- DE69417748D1 DE69417748D1 DE69417748T DE69417748T DE69417748D1 DE 69417748 D1 DE69417748 D1 DE 69417748D1 DE 69417748 T DE69417748 T DE 69417748T DE 69417748 T DE69417748 T DE 69417748T DE 69417748 D1 DE69417748 D1 DE 69417748D1
- Authority
- DE
- Germany
- Prior art keywords
- group
- hydrogen
- carbo
- antiviral
- antineoplastic agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8172793A | 1993-06-23 | 1993-06-23 | |
| PCT/US1994/006119 WO1995000515A1 (en) | 1993-06-23 | 1994-05-31 | Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69417748D1 true DE69417748D1 (de) | 1999-05-12 |
| DE69417748T2 DE69417748T2 (de) | 1999-08-19 |
Family
ID=22166006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69417748T Expired - Fee Related DE69417748T2 (de) | 1993-06-23 | 1994-05-31 | Carbo-acyclische nukleosidderivate als antivirale und antineoplastische mittel |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6017923A (de) |
| EP (1) | EP0705264B1 (de) |
| JP (1) | JP3468423B2 (de) |
| CN (1) | CN1040759C (de) |
| AT (1) | ATE178605T1 (de) |
| AU (1) | AU679763B2 (de) |
| CA (1) | CA2165419C (de) |
| DE (1) | DE69417748T2 (de) |
| DK (1) | DK0705264T3 (de) |
| ES (1) | ES2132411T3 (de) |
| FI (1) | FI956246A0 (de) |
| GR (1) | GR3030003T3 (de) |
| HU (1) | HUT73410A (de) |
| IL (1) | IL110051A (de) |
| NO (1) | NO955254L (de) |
| NZ (1) | NZ268479A (de) |
| TW (1) | TW269690B (de) |
| WO (1) | WO1995000515A1 (de) |
| ZA (1) | ZA944344B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6620977B1 (en) | 1998-01-30 | 2003-09-16 | Daiso Co., Ltd. | Process for producing butanetriol derivative |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199575A (en) * | 1978-03-27 | 1980-04-22 | Gunther Roland E | Method of treating dermatitis venenata |
| US4221794A (en) * | 1979-06-21 | 1980-09-09 | Newport Pharmaceuticals International, Inc. | Method of imparting immunomodulating and antiviral activity |
| US4355032B2 (en) * | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
| IL73682A (en) * | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
| US4935427A (en) * | 1987-12-31 | 1990-06-19 | The United States Of America As Represented By The Department Of Health And Human Services | Pyrimidine and purine 1,2-butadiene-4-ols as anti-retroviral agents |
| CA2005815C (en) * | 1988-12-19 | 1999-08-03 | Wellcome Foundation Limited (The) | Antiviral acyclic nucleoside derivatives |
-
1994
- 1994-05-31 AT AT94920695T patent/ATE178605T1/de not_active IP Right Cessation
- 1994-05-31 NZ NZ268479A patent/NZ268479A/en unknown
- 1994-05-31 DE DE69417748T patent/DE69417748T2/de not_active Expired - Fee Related
- 1994-05-31 JP JP50283795A patent/JP3468423B2/ja not_active Expired - Fee Related
- 1994-05-31 AU AU71394/94A patent/AU679763B2/en not_active Ceased
- 1994-05-31 ES ES94920695T patent/ES2132411T3/es not_active Expired - Lifetime
- 1994-05-31 EP EP94920695A patent/EP0705264B1/de not_active Expired - Lifetime
- 1994-05-31 CA CA002165419A patent/CA2165419C/en not_active Expired - Fee Related
- 1994-05-31 WO PCT/US1994/006119 patent/WO1995000515A1/en active IP Right Grant
- 1994-05-31 DK DK94920695T patent/DK0705264T3/da active
- 1994-05-31 CN CN94192562A patent/CN1040759C/zh not_active Expired - Fee Related
- 1994-05-31 HU HU9503707A patent/HUT73410A/hu unknown
- 1994-06-17 ZA ZA944344A patent/ZA944344B/xx unknown
- 1994-06-20 IL IL11005194A patent/IL110051A/xx not_active IP Right Cessation
- 1994-06-20 TW TW083105566A patent/TW269690B/zh active
-
1995
- 1995-12-22 FI FI956246A patent/FI956246A0/fi not_active IP Right Cessation
- 1995-12-22 NO NO955254A patent/NO955254L/no unknown
-
1996
- 1996-05-31 US US08/564,296 patent/US6017923A/en not_active Expired - Fee Related
-
1999
- 1999-04-20 GR GR990401082T patent/GR3030003T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ268479A (en) | 1997-07-27 |
| AU7139494A (en) | 1995-01-17 |
| HU9503707D0 (en) | 1996-02-28 |
| DE69417748T2 (de) | 1999-08-19 |
| IL110051A (en) | 2000-01-31 |
| EP0705264A1 (de) | 1996-04-10 |
| CA2165419C (en) | 1999-03-02 |
| CN1125947A (zh) | 1996-07-03 |
| AU679763B2 (en) | 1997-07-10 |
| TW269690B (de) | 1996-02-01 |
| JP3468423B2 (ja) | 2003-11-17 |
| EP0705264B1 (de) | 1999-04-07 |
| US6017923A (en) | 2000-01-25 |
| GR3030003T3 (en) | 1999-07-30 |
| WO1995000515A1 (en) | 1995-01-05 |
| HUT73410A (en) | 1996-07-29 |
| NO955254L (no) | 1996-02-21 |
| ES2132411T3 (es) | 1999-08-16 |
| DK0705264T3 (da) | 1999-10-18 |
| CN1040759C (zh) | 1998-11-18 |
| ATE178605T1 (de) | 1999-04-15 |
| FI956246A (fi) | 1995-12-22 |
| JPH08512030A (ja) | 1996-12-17 |
| FI956246A0 (fi) | 1995-12-22 |
| IL110051A0 (en) | 1994-10-07 |
| NO955254D0 (no) | 1995-12-22 |
| ZA944344B (en) | 1995-02-15 |
| CA2165419A1 (en) | 1994-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |