GB2340490A - Diphenylacetic acid derivatives and their use as antiviral agents - Google Patents
Diphenylacetic acid derivatives and their use as antiviral agentsInfo
- Publication number
- GB2340490A GB2340490A GB9926138A GB9926138A GB2340490A GB 2340490 A GB2340490 A GB 2340490A GB 9926138 A GB9926138 A GB 9926138A GB 9926138 A GB9926138 A GB 9926138A GB 2340490 A GB2340490 A GB 2340490A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- acid derivatives
- antiviral agents
- diphenylacetic acid
- diphenylvalerate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/10—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to an acyclic carbon atom of a carbon skeleton containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A new broad-spectrum anti-viral compound for the treatment of viral infections, such as human immune deficiency virus. The compound has general formula (I). Ar<SP>1</SP> and Ar<SP>2</SP> are each either a phenyl group or substituted aromatic group; R<SP>1</SP> is a primary, secondary or tertiary alkyl or alkenyl group, a phenyl or hydrogen; R<SP>2</SP> is an alkyl group, a primary, secondary or tertiary alkyl amino group or hydrogen; and X is C, O, N or S. Preferred compounds include diethylamino-ethyl-2,2-diphenylvalerate and aminoethyl-2,2-diphenylvalerate.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9709073.2A GB9709073D0 (en) | 1997-05-07 | 1997-05-07 | Broad-spectrum anti-viral |
GBGB9720837.5A GB9720837D0 (en) | 1997-05-07 | 1997-10-02 | Anti-viral compounds |
GBGB9804337.5A GB9804337D0 (en) | 1998-03-03 | 1998-03-03 | Anti-viral compounds |
PCT/GB1998/001313 WO1998050022A1 (en) | 1997-05-07 | 1998-05-06 | Diphenylacetic acid derivatives and their use as antiviral agents |
Publications (2)
Publication Number | Publication Date |
---|---|
GB9926138D0 GB9926138D0 (en) | 2000-01-12 |
GB2340490A true GB2340490A (en) | 2000-02-23 |
Family
ID=27268832
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9926138A Withdrawn GB2340490A (en) | 1997-05-07 | 1998-05-06 | Diphenylacetic acid derivatives and their use as antiviral agents |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU7343398A (en) |
GB (1) | GB2340490A (en) |
WO (1) | WO1998050022A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2347858A (en) * | 1999-03-18 | 2000-09-20 | Lovesgrove Res Ltd | Anti-viral compounds |
BR112016028081A2 (en) | 2014-05-30 | 2017-08-22 | Sphaera Pharma Private Ltd | NEW COMPOUNDS AS ANTITUBERCULAR AGENTS |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2714376A1 (en) * | 1993-12-29 | 1995-06-30 | Khimbio | Di:methyl amino ethyl phenyl propionate(s) |
-
1998
- 1998-05-06 AU AU73433/98A patent/AU7343398A/en not_active Abandoned
- 1998-05-06 GB GB9926138A patent/GB2340490A/en not_active Withdrawn
- 1998-05-06 WO PCT/GB1998/001313 patent/WO1998050022A1/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2714376A1 (en) * | 1993-12-29 | 1995-06-30 | Khimbio | Di:methyl amino ethyl phenyl propionate(s) |
Non-Patent Citations (9)
Title |
---|
A KREUTZBERGER ET AL: ARCHIV DER PHARMAZIE vol. 307, no.10 1974 pgs 766-774 XP002075775 * |
BIOCHEM PHARMACOL vol29 no19, 1980 pgs 2577-2582 * |
CHEMICAL ABSTRACTS vol68 no15, 1968 abstract 66647b S AARON SON ET AL pg 6420 XP002075779 * |
CHEMICAL ABSTRACTS vol73 no5, 1970 US abstract 23655p H SESAME ET AL pg 213 XP002075781 * |
CHEMICAL ABSTRACTS vol84 no5, Feb 1976, abstract no. 0682a G TSUCHIHASHI pg 425, XP002075778 * |
CHEMICAL ABSTRACTS vol94 no9, 1981 US abstract 57860a P J BARBER ET AL pg 12 XP002075782 * |
CHEMICLA ABSTRACTS vol112 no15, 1990 US abstract 131959y E MALVOISIN ET AL pg 24 XP002075780 * |
MC LU ET AL "Molecular modification.." JOURNAL OF MEDICINAL CHEMISTRY vol30. no2, pgs 273-278 1987 * |
T UEDA ET AL - CHEMICAL & PHARMACEUTICAL BULLETIN vol16 no121968 pgs 2355-2361 XP002075777 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998050022A1 (en) | 1998-11-12 |
AU7343398A (en) | 1998-11-27 |
GB9926138D0 (en) | 2000-01-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |