IL109904A0 - Secondary amines as antidiabetic and antiobesity agents - Google Patents
Secondary amines as antidiabetic and antiobesity agentsInfo
- Publication number
- IL109904A0 IL109904A0 IL10990494A IL10990494A IL109904A0 IL 109904 A0 IL109904 A0 IL 109904A0 IL 10990494 A IL10990494 A IL 10990494A IL 10990494 A IL10990494 A IL 10990494A IL 109904 A0 IL109904 A0 IL 109904A0
- Authority
- IL
- Israel
- Prior art keywords
- pct
- antiobesity agents
- antidiabetic
- date dec
- secondary amines
- Prior art date
Links
- 239000000883 anti-obesity agent Substances 0.000 title abstract 2
- 239000003472 antidiabetic agent Substances 0.000 title abstract 2
- 229940125710 antiobesity agent Drugs 0.000 title abstract 2
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 229940125708 antidiabetic agent Drugs 0.000 title 1
- 150000003335 secondary amines Chemical class 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 235000020997 lean meat Nutrition 0.000 abstract 2
- 230000008021 deposition Effects 0.000 abstract 1
- 229940126904 hypoglycaemic agent Drugs 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7602693A | 1993-06-14 | 1993-06-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL109904A0 true IL109904A0 (en) | 1994-10-07 |
Family
ID=22129472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10990494A IL109904A0 (en) | 1993-06-14 | 1994-06-06 | Secondary amines as antidiabetic and antiobesity agents |
Country Status (22)
Country | Link |
---|---|
US (1) | US5767133A (es) |
EP (1) | EP0703911B1 (es) |
JP (1) | JPH08506348A (es) |
KR (1) | KR960703120A (es) |
CN (1) | CN1129443A (es) |
AT (1) | ATE154935T1 (es) |
AU (1) | AU675536B2 (es) |
BR (1) | BR9406823A (es) |
CA (1) | CA2164009A1 (es) |
CZ (1) | CZ327795A3 (es) |
DE (1) | DE69404039T2 (es) |
DK (1) | DK0703911T3 (es) |
ES (1) | ES2104383T3 (es) |
FI (1) | FI942791A (es) |
GR (1) | GR3024134T3 (es) |
HU (1) | HUT70844A (es) |
IL (1) | IL109904A0 (es) |
NO (1) | NO955047L (es) |
NZ (1) | NZ265692A (es) |
PL (1) | PL312005A1 (es) |
WO (1) | WO1994029290A1 (es) |
ZA (1) | ZA944139B (es) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
CA2171702A1 (en) * | 1995-03-14 | 1996-09-15 | Takashi Sohda | Benzofuran compounds and their use |
WO1996035670A1 (en) * | 1995-05-10 | 1996-11-14 | Pfizer Inc. | β-ADRENERGIC AGONISTS |
WO1996035671A1 (en) * | 1995-05-10 | 1996-11-14 | Pfizer Inc. | β-ADRENERGIC AGONISTS |
US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
GB2305665A (en) * | 1995-09-26 | 1997-04-16 | Merck & Co Inc | Selective ß3 agonists for the treatment of diabetes aand obesity |
TR199800710T2 (xx) * | 1995-10-31 | 1998-08-21 | Pfizer Inc. | 1-(2(2-izoksazol-3-ilbenzofuran-5-iloksi) ethilamino)-3-fenoksi-2(S)-ol haz�rlanmas� i�in i�lem ve ara maddeler. |
AU715233B2 (en) | 1996-01-10 | 2000-01-20 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel tricyclic compounds and drug compositions containing the same |
US6008361A (en) * | 1996-04-09 | 1999-12-28 | Pfizer Inc. | Substituted pyridines |
EP0801060A1 (en) * | 1996-04-09 | 1997-10-15 | Pfizer Inc. | Heterocyclic Beta-3 Adrenergenic Agonists |
US6031105A (en) * | 1996-04-09 | 2000-02-29 | Pfizer Inc | Substituted pyridines |
US5859044A (en) * | 1996-07-31 | 1999-01-12 | Pfizer Inc. | β-adrenergic agonists |
ATE215369T1 (de) | 1996-09-05 | 2002-04-15 | Lilly Co Eli | Carbazolanaloge als selektive beta3-adrenergische agonisten |
ATE247641T1 (de) * | 1996-11-14 | 2003-09-15 | Pfizer | Pyridin-zwischenprodukte, verwendbar zur herstellung von beta-adrenergischen rezeptor- agonisten |
TR199901063T2 (xx) | 1996-11-14 | 1999-08-23 | Pfizer Inc. | �kame edilmi� piridinler i�in i�lem. |
AU6852898A (en) * | 1997-04-17 | 1998-11-11 | Takeda Chemical Industries Ltd. | Thermogenic composition and benzazepine thermogenics |
CA2296104A1 (en) * | 1997-07-03 | 1999-01-14 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel tricyclic compounds having saturated rings and medicinal compositions containing the same |
CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
US6051586A (en) * | 1997-12-19 | 2000-04-18 | Bayer Corporation | Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
US6469031B1 (en) | 1998-12-18 | 2002-10-22 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
ATE222901T1 (de) * | 1997-12-19 | 2002-09-15 | Bayer Ag | Carboxylsubstituierte chromanderivate zur verwendung als beta 3 adrenorezeptor-agonisten |
US6121271A (en) * | 1998-05-12 | 2000-09-19 | American Home Products Corporation | Naphtho[2,3-B]heteroar-4-yl derivatives |
WO1999058522A1 (en) * | 1998-05-12 | 1999-11-18 | American Home Products Corporation | Naphtho[2,3-b]heteroar-4-yl derivatives |
AU2619800A (en) * | 1999-01-27 | 2000-08-18 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-ht(2c)) agonists |
US7045545B1 (en) | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
DE19932314A1 (de) | 1999-07-10 | 2001-01-11 | Merck Patent Gmbh | Benzofuranderivate |
WO2001044187A1 (fr) * | 1999-12-16 | 2001-06-21 | Asahi Kasei Kabushiki Kaisha | Nouveaux composes tricycliques substitues |
AU5257401A (en) * | 2000-04-28 | 2001-11-12 | Asahi Chemical Ind | Novel bicyclic compounds |
AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
WO2002100850A1 (fr) * | 2001-06-08 | 2002-12-19 | Kuraray Co., Ltd. | Procedes de preparation de composes heterocycliques |
KR100816527B1 (ko) * | 2001-09-12 | 2008-04-10 | 한국화학연구원 | 페닐테트라졸 유도체로 치환된 β-아미노알코올 화합물 |
DE60228990D1 (de) * | 2001-10-25 | 2008-10-30 | Asahi Kasei Pharma Corp | Bicyclische verbindung |
AU2003209527A1 (en) * | 2002-02-27 | 2003-09-09 | Pfizer Products Inc. | Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol |
WO2003072547A1 (en) * | 2002-02-27 | 2003-09-04 | Pfizer Products Inc. | PROCESSES AND INTERMEDIATES USEFUL IN PREPARING β3-ADRENERGIC RECEPTOR AGONISTS |
US6864268B2 (en) | 2002-02-27 | 2005-03-08 | Pfizer Inc. | β3 adrenergic receptor agonists |
KR20050047552A (ko) * | 2002-10-11 | 2005-05-20 | 화이자 인코포레이티드 | 베타-2 작용제로서의 인돌 유도체 |
EP1407769A1 (en) * | 2002-10-11 | 2004-04-14 | Pfizer Limited | Indole derivatives as beta-2 agonists |
US6844362B2 (en) | 2002-10-11 | 2005-01-18 | Pfizer Inc | Indole derivatives useful for the treatment of diseases |
AU2003300131A1 (en) * | 2003-01-06 | 2004-11-04 | Eli Lilly And Company | Indole derivatives as ppar modulators |
EP1460064A1 (en) * | 2003-03-14 | 2004-09-22 | Pfizer Limited | Indole-2-carboxamide derivatives useful as beta-2 agonists |
EP1660484B1 (en) | 2003-05-09 | 2008-08-27 | F. Hoffmann-La Roche Ag | Methyl indoles and methyl pyrrolopyridines as alpha-1 adrenergic agonists |
JP2008100916A (ja) * | 2005-01-24 | 2008-05-01 | Dainippon Sumitomo Pharma Co Ltd | インドール類およびそれを含む医薬組成物 |
GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
KR20160129109A (ko) | 2008-05-23 | 2016-11-08 | 아미라 파마슈티칼스 인코포레이티드 | 5-리폭시게나아제 활성화 단백질 억제제 |
CA2740772A1 (en) | 2008-10-09 | 2010-04-15 | Asahi Kasei Pharma Corporation | Indazole compounds |
AU2009301797B2 (en) * | 2008-10-09 | 2012-03-01 | Asahi Kasei Pharma Corporation | Indazole derivative |
US20100222404A1 (en) * | 2008-11-04 | 2010-09-02 | Asahi Kasei Pharma Corporation | Indazole derivative dihydrochloride |
US20100173829A1 (en) * | 2008-11-07 | 2010-07-08 | Aston University | Glycoproteins Having Lipid Mobilizing Properties and Therapeutic Uses Thereof |
EP2563123B1 (en) * | 2010-04-30 | 2018-04-25 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
AU2021289434A1 (en) | 2020-06-08 | 2023-01-19 | Tactogen Inc | Advantageous benzofuran compositions for mental disorders or enhancement |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1268960A (en) * | 1969-09-18 | 1972-03-29 | Sandoz Ltd | Indole derivatives |
US3699123A (en) * | 1970-03-24 | 1972-10-17 | Sandoz Ltd | 4-(3-amino-2-hydroxy-propoxy) indole derivatives |
DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
EP0021636B1 (en) * | 1979-06-16 | 1982-12-01 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
EP0025331B1 (en) * | 1979-09-06 | 1983-03-02 | Beecham Group Plc | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them |
EP0029320B1 (en) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions |
CA1175851A (en) * | 1980-09-26 | 1984-10-09 | Beecham Group Limited | Secondary amines |
GR75101B (es) * | 1980-10-23 | 1984-07-13 | Pfizer | |
EP0052963B1 (en) * | 1980-11-20 | 1985-02-20 | Beecham Group Plc | Secondary amines |
FR2523964B1 (fr) * | 1982-03-23 | 1985-09-27 | Sanofi Sa | Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation |
JPS60202872A (ja) * | 1984-03-27 | 1985-10-14 | Kaken Pharmaceut Co Ltd | ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤 |
US4882433A (en) * | 1985-10-30 | 1989-11-21 | The Upjohn Company | 3'-pyridinylalkylinden- and 3'-pyridinylalkylindol-2-carboxylic acids and analogs |
GB8528633D0 (en) * | 1985-11-21 | 1985-12-24 | Beecham Group Plc | Compounds |
US4886814A (en) * | 1986-03-13 | 1989-12-12 | Dr. Karl Thomas Gmbh | Substituted thiazoles and oxazoles and 2-hydroxy-morpholines |
GB8714901D0 (en) * | 1986-07-23 | 1987-07-29 | Ici Plc | Amide derivatives |
GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
US5061727A (en) * | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
JPH08165276A (ja) * | 1994-12-14 | 1996-06-25 | Dainippon Pharmaceut Co Ltd | 2−アルキルアミノ−1−フェニルエタノール誘導体 |
-
1994
- 1994-05-20 PL PL94312005A patent/PL312005A1/xx unknown
- 1994-05-20 WO PCT/IB1994/000117 patent/WO1994029290A1/en not_active Application Discontinuation
- 1994-05-20 CZ CZ953277A patent/CZ327795A3/cs unknown
- 1994-05-20 EP EP94914531A patent/EP0703911B1/en not_active Expired - Lifetime
- 1994-05-20 AT AT94914531T patent/ATE154935T1/de not_active IP Right Cessation
- 1994-05-20 CN CN94193087A patent/CN1129443A/zh active Pending
- 1994-05-20 BR BR9406823A patent/BR9406823A/pt not_active Application Discontinuation
- 1994-05-20 AU AU66870/94A patent/AU675536B2/en not_active Ceased
- 1994-05-20 ES ES94914531T patent/ES2104383T3/es not_active Expired - Lifetime
- 1994-05-20 DK DK94914531.2T patent/DK0703911T3/da active
- 1994-05-20 US US08/569,152 patent/US5767133A/en not_active Expired - Fee Related
- 1994-05-20 KR KR1019950705694A patent/KR960703120A/ko not_active Application Discontinuation
- 1994-05-20 DE DE69404039T patent/DE69404039T2/de not_active Expired - Fee Related
- 1994-05-20 JP JP6520401A patent/JPH08506348A/ja active Pending
- 1994-05-20 CA CA002164009A patent/CA2164009A1/en not_active Abandoned
- 1994-05-20 NZ NZ265692A patent/NZ265692A/en unknown
- 1994-06-06 IL IL10990494A patent/IL109904A0/xx unknown
- 1994-06-13 FI FI942791A patent/FI942791A/fi not_active Application Discontinuation
- 1994-06-13 HU HU9401761A patent/HUT70844A/hu unknown
- 1994-06-13 ZA ZA944139A patent/ZA944139B/xx unknown
-
1995
- 1995-12-13 NO NO955047A patent/NO955047L/no unknown
-
1997
- 1997-07-16 GR GR970401784T patent/GR3024134T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0703911T3 (da) | 1997-10-06 |
US5767133A (en) | 1998-06-16 |
KR960703120A (ko) | 1996-06-19 |
ZA944139B (en) | 1995-12-13 |
DE69404039D1 (de) | 1997-08-07 |
EP0703911A1 (en) | 1996-04-03 |
CZ327795A3 (en) | 1996-08-14 |
DE69404039T2 (de) | 1997-10-16 |
ATE154935T1 (de) | 1997-07-15 |
AU675536B2 (en) | 1997-02-06 |
NO955047D0 (no) | 1995-12-13 |
EP0703911B1 (en) | 1997-07-02 |
CN1129443A (zh) | 1996-08-21 |
FI942791A (fi) | 1994-12-15 |
ES2104383T3 (es) | 1997-10-01 |
NO955047L (no) | 1995-12-13 |
JPH08506348A (ja) | 1996-07-09 |
PL312005A1 (en) | 1996-04-01 |
AU6687094A (en) | 1995-01-03 |
BR9406823A (pt) | 1996-03-26 |
HU9401761D0 (en) | 1994-09-28 |
FI942791A0 (fi) | 1994-06-13 |
GR3024134T3 (en) | 1997-10-31 |
HUT70844A (en) | 1995-11-28 |
CA2164009A1 (en) | 1994-12-22 |
WO1994029290A1 (en) | 1994-12-22 |
NZ265692A (en) | 1997-02-24 |
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