IL107708A0 - Proteins - Google Patents

Proteins

Info

Publication number
IL107708A0
IL107708A0 IL10770893A IL10770893A IL107708A0 IL 107708 A0 IL107708 A0 IL 107708A0 IL 10770893 A IL10770893 A IL 10770893A IL 10770893 A IL10770893 A IL 10770893A IL 107708 A0 IL107708 A0 IL 107708A0
Authority
IL
Israel
Prior art keywords
cdrs
barrel
cyclic permutation
central beta
ligand binding
Prior art date
Application number
IL10770893A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929224588A external-priority patent/GB9224588D0/en
Priority claimed from GB929227189A external-priority patent/GB9227189D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL107708A0 publication Critical patent/IL107708A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL10770893A 1992-11-23 1993-11-22 Proteins IL107708A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929224588A GB9224588D0 (en) 1992-11-23 1992-11-23 Proteins
GB929227189A GB9227189D0 (en) 1992-12-31 1992-12-31 Proteins

Publications (1)

Publication Number Publication Date
IL107708A0 true IL107708A0 (en) 1994-02-27

Family

ID=26302037

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10770893A IL107708A0 (en) 1992-11-23 1993-11-22 Proteins

Country Status (8)

Country Link
EP (1) EP0673417B1 (xx)
AT (1) ATE242804T1 (xx)
AU (1) AU5530394A (xx)
DE (1) DE69333044T2 (xx)
GB (2) GB9323648D0 (xx)
IL (1) IL107708A0 (xx)
MX (1) MX9307316A (xx)
WO (1) WO1994012625A2 (xx)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
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EP3443096B1 (en) 2016-04-15 2023-03-01 Novartis AG Compositions and methods for selective expression of chimeric antigen receptors
WO2017210617A2 (en) 2016-06-02 2017-12-07 Porter, David, L. Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
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EA202090104A1 (ru) 2017-06-22 2020-04-09 Новартис Аг Молекулы антител к cd73 и пути их применения
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US20210179709A1 (en) 2017-10-31 2021-06-17 Novartis Ag Anti-car compositions and methods
WO2019089753A2 (en) 2017-10-31 2019-05-09 Compass Therapeutics Llc Cd137 antibodies and pd-1 antagonists and uses thereof
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US20210147547A1 (en) 2018-04-13 2021-05-20 Novartis Ag Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
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US20200109195A1 (en) 2018-05-21 2020-04-09 Compass Therapeutics Llc Compositions and methods for enhancing the killing of target cells by nk cells
WO2019226658A1 (en) 2018-05-21 2019-11-28 Compass Therapeutics Llc Multispecific antigen-binding compositions and methods of use
WO2019227003A1 (en) 2018-05-25 2019-11-28 Novartis Ag Combination therapy with chimeric antigen receptor (car) therapies
WO2019232244A2 (en) 2018-05-31 2019-12-05 Novartis Ag Antibody molecules to cd73 and uses thereof
JP7438988B2 (ja) 2018-06-13 2024-02-27 ノバルティス アーゲー Bcmaキメラ抗原受容体及びその使用
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US20220088075A1 (en) 2019-02-22 2022-03-24 The Trustees Of The University Of Pennsylvania Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
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US20230057071A1 (en) 2019-12-20 2023-02-23 Novartis Ag Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
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Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules

Also Published As

Publication number Publication date
DE69333044T2 (de) 2004-04-29
EP0673417A1 (en) 1995-09-27
MX9307316A (es) 1994-06-30
AU5530394A (en) 1994-06-22
GB9323648D0 (en) 1994-01-05
GB2287247B (en) 1996-08-14
WO1994012625A2 (en) 1994-06-09
GB9509600D0 (en) 1995-07-05
EP0673417B1 (en) 2003-06-11
WO1994012625A3 (en) 1994-07-21
GB2287247A (en) 1995-09-13
DE69333044D1 (de) 2003-07-17
ATE242804T1 (de) 2003-06-15

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