IL107158A0 - Quaternary basic amides,their preparation and pharmaceuticcal compositions containing them - Google Patents

Quaternary basic amides,their preparation and pharmaceuticcal compositions containing them

Info

Publication number
IL107158A0
IL107158A0 IL107158A IL10715893A IL107158A0 IL 107158 A0 IL107158 A0 IL 107158A0 IL 107158 A IL107158 A IL 107158A IL 10715893 A IL10715893 A IL 10715893A IL 107158 A0 IL107158 A0 IL 107158A0
Authority
IL
Israel
Prior art keywords
group
alkyl
preparation
pharmaceuticcal
omega
Prior art date
Application number
IL107158A
Other languages
English (en)
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of IL107158A0 publication Critical patent/IL107158A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
IL107158A 1992-09-30 1993-09-29 Quaternary basic amides,their preparation and pharmaceuticcal compositions containing them IL107158A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9212083A FR2696178B1 (fr) 1992-09-30 1992-09-30 Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.

Publications (1)

Publication Number Publication Date
IL107158A0 true IL107158A0 (en) 1993-12-28

Family

ID=9434374

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107158A IL107158A0 (en) 1992-09-30 1993-09-29 Quaternary basic amides,their preparation and pharmaceuticcal compositions containing them

Country Status (27)

Country Link
EP (1) EP0591040B1 (xx)
JP (2) JP2857041B2 (xx)
KR (1) KR100279084B1 (xx)
CN (1) CN1036652C (xx)
AT (1) ATE176469T1 (xx)
AU (1) AU674875B2 (xx)
BR (1) BR9303982A (xx)
CA (1) CA2107432C (xx)
CZ (1) CZ287272B6 (xx)
DE (1) DE69323375T2 (xx)
DK (1) DK0591040T3 (xx)
ES (1) ES2130238T3 (xx)
FI (1) FI114474B (xx)
FR (1) FR2696178B1 (xx)
GR (1) GR3030000T3 (xx)
HU (2) HU215848B (xx)
IL (1) IL107158A0 (xx)
MX (1) MX9306024A (xx)
MY (1) MY108881A (xx)
NO (1) NO304888B1 (xx)
NZ (1) NZ248821A (xx)
OA (1) OA09869A (xx)
RU (1) RU2120436C1 (xx)
SG (1) SG47807A1 (xx)
SI (1) SI9300513B (xx)
TW (1) TW242625B (xx)
ZA (1) ZA937276B (xx)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
FR2717802B1 (fr) * 1994-03-25 1996-06-21 Sanofi Sa Nouveaux composés aromatiques, procédé pour leur préparation et compositions pharmaceutiques en contenant.
FR2717804B1 (fr) * 1994-03-25 1996-06-21 Sanofi Sa Sels de composés hétéroaromatiques azotés substitués, procédé pour leur préparation et compositions pharmaceutiques en contenant.
PE27997A1 (es) 1994-04-29 1997-09-20 Lilly Co Eli Antagonistas de receptores de taquicininas
JPH10502640A (ja) 1994-07-12 1998-03-10 イーライ・リリー・アンド・カンパニー 異項環タキキニン受容体拮抗物質
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
GB9421709D0 (en) * 1994-10-27 1994-12-14 Zeneca Ltd Therapeutic compounds
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
EP0714891A1 (en) * 1994-11-22 1996-06-05 Eli Lilly And Company Heterocyclic tachykinin receptor antagonists
FR2729954B1 (fr) * 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2729951B1 (fr) * 1995-01-30 1997-04-18 Sanofi Sa Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
FR2751654B1 (fr) * 1996-07-26 1998-10-23 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2729952B1 (fr) * 1995-01-30 1997-04-18 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
US5654316A (en) * 1995-06-06 1997-08-05 Schering Corporation Piperidine derivatives as neurokinin antagonists
AU5951196A (en) * 1995-06-06 1996-12-24 Schering Corporation Substituted benzene-fused hetero- and carbocyclics as neurok inin antagonists
FR2745811B1 (fr) * 1996-03-07 1998-05-22 Sanofi Sa Glutarimide disubstitue procede pour sa preparation, et son utilisation
EP0912178A4 (en) * 1996-05-24 2000-08-16 Lilly Co Eli METHOD FOR TREATING THE HIGH PRESSURE
US5691362A (en) * 1996-06-05 1997-11-25 Schering-Plough Corporation Substituted benzene-fused hetero- and carbocyclics as nuerokinin antagonists
GB9617730D0 (en) * 1996-08-23 1996-10-02 Pfizer Ltd Quarternary ammonium compounds
FR2759584B1 (fr) * 1997-02-17 1999-06-11 Sanofi Sa Composition pharmaceutique pour l'administration orale de composes heterocycliques sous forme ammonium quaternaire
FR2759585B1 (fr) * 1997-02-17 1999-06-11 Sanofi Sa Formulations pharmaceutiques presentees sous forme seche pour l'administration orale d'un compose ammonium quaternaire cyclique
EP0977572A1 (en) * 1997-04-24 2000-02-09 Merck Sharp & Dohme Ltd. Use of nk-1 receptor antagonists for treating eating disorders
GB9712882D0 (en) * 1997-06-18 1997-08-20 Pfizer Ltd Quaternary ammonium compounds
GB9716457D0 (en) * 1997-08-04 1997-10-08 Merck Sharp & Dohme Therapeutic agents
AU738047B2 (en) * 1997-08-04 2001-09-06 Merck Sharp & Dohme Limited Use of NK-1 receptor antagonists for treating mania
AU737019B2 (en) * 1997-08-04 2001-08-09 Merck Sharp & Dohme Limited Use of NK-1 receptor antagonists for treating aggressive behaviour disorders
GB9716463D0 (en) * 1997-08-04 1997-10-08 Merck Sharp & Dohme Therapeutic agents
GB9816897D0 (en) * 1998-08-04 1998-09-30 Merck Sharp & Dohme Therapeutic use
GB9927125D0 (en) 1999-11-16 2000-01-12 Univ Reading The Placental human neurokinin B precursor
US7560549B2 (en) 2004-02-25 2009-07-14 Sankyo Company, Limited Sulfonyloxy derivatives
US9597314B2 (en) 2005-03-22 2017-03-21 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
CA2615813C (en) 2005-07-19 2015-12-15 Azevan Pharmaceuticals, Inc. Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists
CN101641099A (zh) 2007-01-24 2010-02-03 葛兰素集团有限公司 包含3,5-二氨基-6-(2,3-二氯苯基)-1,2,4-三嗪或r(-)-2,4-二氨基-5-(2,3-二氯苯基)-6-氟甲基嘧啶和nk1的药物组合物
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
EP2587919B1 (en) 2010-07-01 2017-12-13 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
SG10202001065SA (en) 2014-03-28 2020-04-29 Azevan Pharmaceuticals Inc Compositions and methods for treating neurodegenerative diseases
RU2722720C1 (ru) * 2016-12-14 2020-06-03 Бейджинг Шоубай Фармасьютикэл Ко., Лтд. Класс бифункциональных соединений со структурой соли четвертичного аммония
WO2019055913A1 (en) 2017-09-15 2019-03-21 Azevan Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN INJURY

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
FR2666185B1 (fr) * 1990-08-21 1992-12-04 Sgs Thomson Microelectronics Convertisseur analogique/numerique a interpolation.
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
DE69323375D1 (de) 1999-03-18
EP0591040A1 (fr) 1994-04-06
MY108881A (en) 1996-11-30
NO304888B1 (no) 1999-03-01
JPH06211850A (ja) 1994-08-02
SG47807A1 (en) 1998-04-17
NO933481L (no) 1994-04-05
HU211889A9 (en) 1995-12-28
EP0591040B1 (fr) 1999-02-03
ATE176469T1 (de) 1999-02-15
JPH10175976A (ja) 1998-06-30
CA2107432C (en) 2000-04-04
FI114474B (fi) 2004-10-29
AU4870893A (en) 1994-04-14
CN1036652C (zh) 1997-12-10
JP2857041B2 (ja) 1999-02-10
CN1088582A (zh) 1994-06-29
FR2696178B1 (fr) 1994-12-30
JP3243212B2 (ja) 2002-01-07
SI9300513B (sl) 2002-02-28
AU674875B2 (en) 1997-01-16
RU2120436C1 (ru) 1998-10-20
KR940007026A (ko) 1994-04-26
NZ248821A (en) 1995-10-26
DK0591040T3 (da) 1999-09-20
HU9302770D0 (en) 1993-12-28
CA2107432A1 (en) 1994-03-31
CZ287272B6 (en) 2000-10-11
SI9300513A (en) 1994-06-30
ES2130238T3 (es) 1999-07-01
KR100279084B1 (ko) 2001-01-15
TW242625B (xx) 1995-03-11
NO933481D0 (no) 1993-09-29
MX9306024A (es) 1994-03-31
OA09869A (fr) 1994-08-15
HUT65759A (en) 1994-07-28
DE69323375T2 (de) 1999-06-24
ZA937276B (en) 1994-04-25
CZ203593A3 (en) 1994-04-13
BR9303982A (pt) 1994-10-25
FR2696178A1 (fr) 1994-04-01
FI934273A0 (fi) 1993-09-29
HU215848B (hu) 1999-04-28
FI934273A (fi) 1994-03-31
GR3030000T3 (en) 1999-07-30

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
HP Change in proprietorship
KB Patent renewed
HC Change of name of proprietor(s)
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees